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List of works by Juan A Asenjo

A mixed mechanistic-electrostatic model to explain pH dependence of glycosyl hydrolase enzyme activity.

scientific article published in June 2004

A population balance model of enzymatic lysis of microbial cells

scientific article published on 01 January 1990

A structured mechanistic model of the kinetics of enzymatic lysis and disruption of yeast cells.

scientific article

A theory of protein-resin interaction in hydrophobic interaction chromatography.

scientific article published in February 2005

An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma.

scientific article published on 26 June 2014

Analysis of metabolic networks of Streptomyces leeuwenhoekii C34 by means of a genome scale model: Prediction of modifications that enhance the production of specialized metabolites

scientific article published on 16 April 2018

Atacama Database: a platform of the microbiome of the Atacama Desert

scientific article published on 18 September 2019

Atacamycins A-C, 22-membered antitumor macrolactones produced by Streptomyces sp. C38. ⬇️

scientific article published on 19 October 2011

Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp.

scientific article

Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert

scientific article

Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique

scientific article

Cloning, expression and decoding of the cold adaptation of a new widely represented thermolabile subtilisin-like protease.

scientific article published on 27 December 2012

Cold adaptation, ca2+ dependency and autolytic stability are related features in a highly active cold-adapted trypsin resistant to autoproteolysis engineered for biotechnological applications

scientific article

Comparative transcriptional analysis of embryoid body versus two-dimensional differentiation of murine embryonic stem cells.

scientific article published on October 2008

Continuous modeling of metabolic networks with gene regulation in yeast and in vivo determination of rate parameters.

scientific article

Current insights on protein behaviour in hydrophobic interaction chromatography.

scientific article published on December 2006

Design and implementation of a high yield production system for recombinant expression of peptides

scientific article

Diversity of culturable actinomycetes in hyper-arid soils of the Atacama Desert, Chile.

scientific article

Dynamic flux balance analysis of biomass and lipid production by Antarctic thraustochytrid Oblongichytrium sp. RT2316-13

scientific article published on 18 June 2020

Effect of surface hydrophobicity distribution on retention of ribonucleases in hydrophobic interaction chromatography.

scientific article published in July 2004

Effect of the growth conditions on the synthesis of a recombinant beta-1,4-endoglucanase in continuous and fed-batch culture

scientific article published on 01 August 2000

Elution relationships to model affinity chromatography using a general rate model.

scientific article published in November 2012

Enzymatic lysis of microbial cells.

scientific article published on 27 April 2007

Extension of the selection of protein chromatography and the rate model to affinity chromatography

scientific article published on November 1, 2010

Extraction of lysozyme and ribonuclease-a using reverse micelles: Limits to protein solubilization.

scientific article published in September 1995

Factors affecting the esterification of lauric acid using an immobilized biocatalyst: Enzyme characterization and studies in a well-mixed reactor.

scientific article published in April 1995

Genome-scale reconstruction of Salinispora tropica CNB-440 metabolism to study strain-specific adaptation.

scientific article published on 27 August 2015

Hydrophobic interaction chromatography for purification of monoPEGylated RNase A

scientific article published on 01 April 2012

Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekii ⬇️

scientific article

Identification of lipase encoding genes from Antarctic seawater bacteria using degenerate primers: expression of a cold-active lipase with high specific activity

scientific article published on 25 October 2014

Improvement of the lytic properties of a beta-1,3-glucanase by directed evolution.

scientific article published in July 2006

Is it possible to predict the average surface hydrophobicity of a protein using only its amino acid composition?

scientific article

Is there a rational method to purify proteins? From expert systems to proteomics.

scientific article published on May 2004

Isolation, purification and preliminary characterization of cryophilic proteases of marine origin.

scientific article published in January 2001

Kinetic model of BiP- and PDI-mediated protein folding and assembly

scientific article published on 01 February 2002

Kinetics of phase separation for polyethylene glycol-phosphate two-phase systems

scientific article published on 01 November 1995

Mathematical correlations for predicting protein retention times in hydrophobic interaction chromatography.

scientific article published in November 2002

Mathematical modeling of elution curves for a protein mixture in ion exchange chromatography applied to high protein concentration.

scientific article published in October 2009

Metabolic analysis of the synthesis of high levels of intracellular human SOD in Saccharomyces cerevisiae rhSOD 2060 411 SGA122.

scientific article published in April 2003

Metabolic flux analysis of embryonic stem cells using three distinct differentiation protocols and comparison to gene expression patterns.

scientific article published on September 2010

Microbiology of hyper-arid environments: recent insights from the Atacama Desert, Chile.

scientific article published on 6 April 2013

Modeling heterocyst pattern formation in cyanobacteria.

scientific article published on 16 June 2009

Molecular characterisation of a thermoactive beta-1,3-glucanase from Oerskovia xanthineolytica.

scientific article published in September 1996

Molecular cloning of a lytic beta-1,3-glucanase gene from Oerskovia xanthineolytica LLG109. A beta-1,3-glucanase able to selectively permeabilize the yeast cell wall.

scientific article published on May 1996

Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins.

scientific article

Non-homogeneous biofilm modeling applied to bioleaching processes

scientific article published on 01 July 2010

Optimal design of protein production plants with time and size factor process models.

scientific article published in March 2000

Optimal operation conditions for protein separation in hydrophobic interaction chromatography

scientific article published on 05 October 2006

Optimal process synthesis for the production of multiple recombinant proteins.

scientific article published in July 2004

Optimization of a biotechnological multiproduct batch plant design for the manufacture of four different products: A real case scenario.

scientific article

Optimization of batch processes involving simultaneous enzymatic and microbial reactions

scientific article published on 01 May 1991

Optimization of enzymatic lysis of yeast.

scientific article published in October 1988

Phase separation rates of aqueous two-phase systems: correlation with system properties

scientific article published on 01 July 2002

Predicting the behaviour of proteins in hydrophobic interaction chromatography. 2. Using a statistical description of their surface amino acid distribution.

scientific article published on 27 December 2005

Prediction of protein retention in hydrophobic interaction chromatography.

scientific article

Prediction of retention times of proteins in hydrophobic interaction chromatography using only their amino acid composition.

scientific article published on 8 September 2005

Prediction of the partitioning behaviour of proteins in aqueous two-phase systems using only their amino acid composition.

scientific article

Production of cell-penetrating peptides in Escherichia coli using an intein-mediated system.

scientific article published on 14 January 2015

Protein partitioning equilibrium between the aqueous poly(ethylene glycol) and salt phases and the solid protein phase in poly(ethylene glycol)-salt two-phase systems.

scientific article published in October 1996

Protein purification using chromatography: selection of type, modelling and optimization of operating conditions.

scientific article published on March 2009

Rational design of purification processes for recombinant proteins

scientific article published on 01 December 1992

Reducing the allowable kinetic space by constructing ensemble of dynamic models with the same steady-state flux.

scientific article published on 12 November 2010

Selection of chromatographic protein purification operations based on physicochemical properties

scientific article published on 01 May 1994

Stoichiometric model and flux balance analysis for a mixed culture of Leptospirillum ferriphilum and Ferroplasma acidiphilum.

scientific article published on 23 December 2014

Streptomyces atacamensis sp. nov., isolated from an extreme hyper-arid soil of the Atacama Desert, Chile.

scientific article

Streptomyces bullii sp. nov., isolated from a hyper-arid Atacama Desert soil.

scientific article

Streptomyces deserti sp. nov., isolated from hyper-arid Atacama Desert soil.

scientific article

Studies on the purification of peroxidase from horseradish roots using reverse micelles

scientific article published on 01 April 1996

The Monod equation and mass transfer.

scientific article published in January 1995

The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2

scientific article

The application of aqueous two-phase systems to the purification of pharmaceutical proteins from transgenic sheep milk.

scientific article published in January 1997

The rational selection of purification processes for proteins: an expert system for downstream processing design.

scientific article published on May 1994

The surface exposed amino acid residues of monomeric proteins determine the partitioning in aqueous two-phase systems

scientific article published on 01 April 2002

Viral vectors for the treatment of alcoholism: use of metabolic flux analysis for cell cultivation and vector production.

scientific article published on 6 October 2009

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