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List of works by Meghan E McGee-Lawrence

Aberrant bone density in aging mice lacking the adenosine transporter ENT1.

scientific article

Alterations in vitamin D metabolite, parathyroid hormone and fibroblast growth factor-23 concentrations in sclerostin-deficient mice permit the maintenance of a high bone mass.

scientific article

Black bear parathyroid hormone has greater anabolic effects on trabecular bone in dystrophin-deficient mice than in wild type mice

scientific article published on 11 May 2012

Black bears with longer disuse (hibernation) periods have lower femoral osteon population density and greater mineralization and intracortical porosity.

scientific article

Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal stem cells.

scientific article

Commonly used adjuvants (liquid soap, foam sanitizer, or ultrasound gel) do not improve strength or curing time of fiberglass cast material.

scientific article

Conditional deletion of Hdac3 in osteoprogenitor cells attenuates diet-induced systemic metabolic dysfunction.

scientific article published on 7 February 2015

Decreased pericellular matrix production and selection for enhanced cell membrane repair may impair osteocyte responses to mechanical loading in the aging skeleton

scientific article published on 19 November 2019

Defining osteoblast and adipocyte lineages in the bone marrow

scientific article published on 18 May 2018

Deletion of Estrogen Receptor Beta in Osteoprogenitor Cells Increases Trabecular but Not Cortical Bone Mass in Female Mice.

scientific article published on 29 September 2015

Enhanced prostacyclin formation and Wnt signaling in sclerostin deficient osteocytes and bone.

scientific article

Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice

scientific article published on 10 October 2016

Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice

scientific article published on 13 June 2018

Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2

scientific article

Grizzly bears (Ursus arctos horribilis) and black bears (Ursus americanus) prevent trabecular bone loss during disuse (hibernation).

scientific article published on 21 August 2009

Hdac-mediated control of endochondral and intramembranous ossification

scientific article published on January 2011

Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells

scientific article published on 24 July 2015

Histone Deacetylases in Bone Development and Skeletal Disorders.

scientific article

Histone deacetylase 3 depletion in osteo/chondroprogenitor cells decreases bone density and increases marrow fat

scientific article (publication date: 2010)

Histone deacetylase 3 is required for maintenance of bone mass during aging

scientific article

Histone deacetylase inhibition destabilizes the multi-potent state of uncommitted adipose-derived mesenchymal stromal cells

scientific article

Histone deacetylase inhibition promotes osteoblast maturation by altering the histone H4 epigenome and reduces Akt phosphorylation.

scientific article published on 12 August 2013

Histone deacetylases in skeletal development and bone mass maintenance ⬇️

scientific article published on December 22, 2010

Induction of fully stabilized cortical bone defects to study intramembranous bone regeneration.

scientific article published on January 2015

Inhibition of Osteocyte Membrane Repair Activity via Dietary Vitamin E Deprivation Impairs Osteocyte Survival ⬇️

scientific article published on 24 October 2018

Kynurenine Promotes RANKL-Induced Osteoclastogenesis In Vitro by Activating the Aryl Hydrocarbon Receptor Pathway

scientific article published on 26 October 2020

Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity

scientific article published on 25 August 2017

Loss of histone methyltransferase Ezh2 stimulates an osteogenic transcriptional program in chondrocytes but does not affect cartilage development

scientific article published in Journal of Biological Chemistry

Mammalian hibernation as a model of disuse osteoporosis: the effects of physical inactivity on bone metabolism, structure, and strength.

scientific article published on 08 October 2008

Mechanical loading disrupts osteocyte plasma membranes which initiates mechanosensation events in bone

scientific article published on 29 July 2017

Osteoblasts protect AML cells from SDF-1-induced apoptosis.

scientific article

Phlpp1 facilitates post-traumatic osteoarthritis and is induced by inflammation and promoter demethylation in human osteoarthritis.

scientific article published on 30 December 2015

RUNX3 facilitates growth of Ewing sarcoma cells

scientific article published on December 2014

Reply to vorinostat induced bone loss in mice

article

Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice.

scientific article

Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice

scientific article published on 7 January 2013

Sclerostin alters serum vitamin D metabolite and fibroblast growth factor 23 concentrations and the urinary excretion of calcium

scientific article published on 25 March 2013

Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification

scientific article

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts.

scientific article

Suppressed bone remodeling in black bears conserves energy and bone mass during hibernation

scientific article published in July 2015

The Ewing's sarcoma fusion protein, EWS-FLI, binds Runx2 and blocks osteoblast differentiation.

scientific article published on November 2010

The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss

scientific article

Thirteen-lined ground squirrels (Ictidomys tridecemlineatus) show microstructural bone loss during hibernation but preserve bone macrostructural geometry and strength ⬇️

scientific article published on April 15, 2011

Transient Cell Membrane Disruptions induce Calcium Waves in Corneal Keratocytes

scientific article published on 18 February 2020

Update on Wnt signaling in bone cell biology and bone disease.

scientific article

Yellow-bellied marmots (Marmota flaviventris) preserve bone strength and microstructure during hibernation.

scientific article

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