List of works by Paul A Flecknell

A case of suspected ventricular pre-excitation in the cat

scientific article published on 01 January 1979

A cervical mass in a laboratory rhesus macaque (Macaca mulatta): Suspicion of air sacculitis

scientific article published on 10 November 2020

A combination of alfaxalone, medetomidine and midazolam for the chemical immobilization of Rhesus macaque (Macaca mulatta): Preliminary results.

scientific article

A comparison in neonatal piglets of model-dependent and model-independent methods for measuring glucose turnover

scientific article published on 01 November 1987

A comparison of abdominal and scrotal approach methods of vasectomy and the influence of analgesic treatment in laboratory mice.

scientific article

A comparison of medetomidine and its active enantiomer dexmedetomidine when administered with ketamine in mice

scientific article

A comparison of the effects of buprenorphine, carprofen and flunixin following laparotomy in rats

scientific article published on 01 August 1994

A new porcine model of reperfusion injury after lung transplantation.

scientific article published in April 1999

A preliminary investigation into the practicality of use and duration of action of slow-release preparations of morphine and hydromorphone in laboratory rats.

scientific article published on 26 October 2009

A preparation for the study of metabolism in the conscious, unrestrained, normal or intra-uterine growth-retarded piglet [proceedings]

scientific article published on 01 June 1979

A surgical approach in the treatment of preputial gland abscesses in mice

scientific article published on 19 January 2016

Accurate measurement of cerebral metabolism in the conscious, unrestrained neonatal piglet. I. Blood flow

scientific article published on 01 January 1982

Accurate measurement of cerebral metabolism in the conscious, unrestrained neonatal piglet. II. Glucose and oxygen utilization.

scientific article published in January 1982

Affective state and quality of life in mice

scientific article published on 02 February 2011

An alternative method of endotracheal intubation of common marmosets (Callithrix jacchus).

scientific article published on 2 November 2011

Anaesthesia and post-operative analgesia following experimental surgery in laboratory rodents: are we making progress?

scientific article

Anaesthesia in rabbits.

scientific article published in August 1982

Anaesthesia of animals for biomedical research.

scientific article

Anaesthesia of guinea pigs

Anaesthesia of laboratory rabbits using etorphine/methotrimeprazine and midazolam.

scientific article published in January 1995

Anaesthesia with a combination of ketamine and medetomidine in the rabbit: effect of premedication with buprenorphine.

scientific article published on 10 March 2010

Anaesthesia with ketamine/medetomidine in the rabbit: influence of route of administration and the effect of combination with butorphanol.

scientific article published in January 2002

Anaesthetic risks to staff ⬇️

scientific article published on February 14, 1981

Analgesia from a veterinary perspective.

scientific article published on 19 April 2008

Analgesics promote welfare and sustain tumour growth in orthotopic 4T1 and B16 mouse cancer models.

scientific article published in January 2017

Are we looking in the wrong place? Implications for behavioural-based pain assessment in rabbits (Oryctolagus cuniculi) and beyond?

scientific article

Assessing and managing pain and distress for ethics committees

scientific article published on 01 June 2004

Assessing animal health and welfare and recognising pain and distress.

scientific article published in January 2007

Assessing the welfare of genetically altered mice.

scientific article

Assessment of blood flow through the lung using laser Doppler flowmetry.

scientific article

Assessment of ketamine and medetomidine anaesthesia in the domestic rabbit

scientific article published in September 2005

Automated analysis of postoperative behaviour: assessment of HomeCageScan as a novel method to rapidly identify pain and analgesic effects in mice.

scientific article published on 17 November 2008

Behavioural effects of laparotomy and analgesic effects of ketoprofen and carprofen in rats.

scientific article

Behavioural effects of ovariohysterectomy and oral administration of meloxicam in laboratory housed rabbits.

scientific article published on 19 March 2009

Buprenorphine: a reappraisal of its antinociceptive effects and therapeutic use in alleviating post-operative pain in animals.

scientific article

Castration of horses and analgesia

scientific article published on 01 August 2001

Catheterization of the sagittal sinus in the neonatal pig

scientific article published on 01 January 1983

Cerebral blood flow and cerebral metabolism in normal and intrauterine growth retarded neonatal piglets

scientific article published on 01 February 1983

Chronic relapsing polyradiculoneuritis in a cat

scientific article published on 01 January 1978

Clinical, Biochemical and Haematological Reference Values in Normal Experimental Animals.

scientific article

Combining nitrous oxide with carbon dioxide decreases the time to loss of consciousness during euthanasia in mice--refinement of animal welfare?

scientific article

Comparative effects of vasectomy surgery and buprenorphine treatment on faecal corticosterone concentrations and behaviour assessed by manual and automated analysis methods in C57 and C3H mice

scientific article

Comparison of electroencephalogram activity and auditory evoked responses during isoflurane and halothane anaesthesia in the rat ⬇️

scientific article published on January 1, 2003

Comparison of emergence times and quality between isoflurane and sevoflurane in rhesus macaque ( Macaca mulatta) undergoing neurosurgical procedure

scientific article

Comparison of the effects of ketamine and fentanyl-midazolam-medetomidine for sedation of rhesus macaques (Macaca mulatta).

scientific article

Comparison of the effects of oral or subcutaneous carprofen or ketoprofen in rats undergoing laparotomy

scientific article published on 01 January 1999

Controlled reperfusion and pentoxifylline modulate reperfusion injury after single lung transplantation

scientific article published on 01 June 1998

Creation of porcine liver tumor using human hepatoma cell lines: experimental study.

scientific article

Do mice have a pain face?

scientific article published on 01 June 2010

Dose regimens of human growth hormone: effects of continuous infusion and of a gelatin vehicle on growth in rats and rate of absorption in rabbits

scientific article published on 01 November 1980

Effects of different propofol infusion rates on EEG activity and AEP responses in rats.

scientific article published in October 2003

Effects of repeated anaesthesia with ketamine/medetomidine and of pre-anaesthetic administration of buprenorphine in rats.

scientific article published in April 2000

Effects of vasectomy surgery and meloxicam treatment on faecal corticosterone levels and behaviour in two strains of laboratory mouse

scientific article published on 28 December 2006

Efficacy of Intrathecal Morphine in a Model of Surgical Pain in Rats

scientific article

Enhancing collaboration in the UK animal welfare research community

scientific article published in February 2016

Evaluation of EMLA cream for preventing pain during tattooing of rabbits: changes in physiological, behavioural and facial expression responses

scientific article

Evaluation of Using Behavioural Changes to Assess Post-Operative Pain in the Guinea Pig (Cavia porcellus).

scientific article published on September 2016

Evaluation of a short duration behaviour-based post-operative pain scoring system in rats.

scientific article published in January 2003

Evaluation of auditory evoked potentials to predict depth of anaesthesia during fentanyl/fluanisone-midazolam anaesthesia in rats.

scientific article published in October 2001

Evaluation of the efficacy of a novel electronic pain assessment device, the Pain Gauge, for measuring postoperative pain in rats.

scientific article published in January 2007

Facial expression: An under-utilised tool for the assessment of welfare in mammals.

scientific article published on 8 February 2017

Fentanyl and medetomidine anaesthesia in the rat and its reversal using atipamazole and either nalbuphine or butorphanol

scientific article published on January 1, 1992

Fetal development in relation to gestational age in the piglet

scientific article published on 01 January 1980

Functional assessment of non-heart-beating donor lungs: prediction of post-transplant function

scientific article published on 01 July 2001

Glucose homeostasis in the newborn: effects of an intravenous glucose infusion in normal and intra-uterine growth-retarded neonatal piglets

scientific article published on 01 January 1987

Haemodialysing babies weighing <8 kg with the Newcastle infant dialysis and ultrafiltration system (Nidus): comparison with peritoneal and conventional haemodialysis

scientific article

Handling method alters the hedonic value of reward in laboratory mice

scientific article

Hospice and palliative care

Immunological tolerance induced by in utero injection ⬇️

scientific article published on February 1, 1983

Impact of Stroke Therapy Academic Industry Roundtable (STAIR) Guidelines on Peri-Anesthesia Care for Rat Models of Stroke: A Meta-Analysis Comparing the Years 2005 and 2015.

scientific article

Improvements in lung compliance after pulmonary transplantation: correlation with interleukin 8 expression.

scientific article published in April 2003

Induction of anaesthesia with desflurane and isoflurane in the rabbit.

scientific article published in April 2001

Induction of anaesthesia with halothane and isoflurane in the rabbit: a comparison of the use of a face-mask or an anaesthetic chamber.

scientific article published in January 1996

Influence of early neonatal experience on nociceptive responses and analgesic effects in rats.

scientific article

Injectable anaesthetic techniques in 2 species of gerbil (Meriones libycus and Meriones unguiculatus).

scientific article published in April 1983

Ketamine and its use in the pig. Recommendations of the Consensus meeting on Ketamine Anaesthesia in Pigs, Bergen 1994. Ketamine Consensus Working Group.

scientific article published on July 1996

Long-term anaesthesia with alfentanil and midazolam for lung transplantation in the dog.

scientific article published in July 1989

Luxation of the patella in cats

scientific article published on June 18, 1977

MRI-guided stereotaxic brain surgery in the infant and adult common marmoset

scientific article published on 23 June 2016

Minimally invasive technique for intrathecal administration of morphine in rats: practicality and antinociceptive properties.

scientific article

Modulation of reperfusion injury after single lung transplantation by pentoxifylline, inositol polyanions, and sin-1.

scientific article

Neuroleptanalgesia in the rabbit.

scientific article published in April 1983

New evidence that the intra-uterine growth-retarded piglet is a member of a discrete subpopulation.

scientific article published in January 1982

Nitric oxide during perfusion improves posttransplantation function of non- heart-beating donor lungs

scientific article published on 01 June 2003

On the use of analgesia in experimental toxinology

scientific article published on 03 January 2013

Opportunities for improving animal welfare in rodent models of epilepsy and seizures

scientific article

Pain assessment and control in laboratory animals

scientific article published on 01 April 2003

Pain relief in experimental animals.

scientific article

Pansteatitis in the cat

scientific article published on 01 February 1978

Pathological features of intra-uterine growth retardation in the piglet: differential effects on organ weights

scientific article published on 01 October 1981

Pets in clinical trials

scientific article

Physiological, Behavioral, and Scientific Impact of Different Fluid Control Protocols in the Rhesus Macaque (Macaca mulatta)

scientific article published on July 2016

Plasma free fatty acid umbilical venous-arterial concentration differences and placental transfer of [14C]palmitic acid in pigs

scientific article published on 01 October 1980

Post-operative analgesia following thoracotomy in the dog: an evaluation of the effects of bupivacaine intercostal nerve block and nalbuphine on respiratory function ⬇️

scientific article published on October 1, 1991

Preliminary assessment of midazolam, fentanyl and fluanisone combination for the sedation of rhesus macaques ( Macaca mulatta).

scientific article published on 8 December 2016

Preservation of the lung. Comparison of topical cooling and cold crystalloid pulmonary perfusion

scientific article published on 01 November 1988

Preservation of the lung: comparison of flush perfusion with cold modified blood and core cooling by cardiopulmonary bypass

scientific article published on 01 January 1991

Production of acute and chronic itch with histamine and contact sensitizers in the mouse and guinea pig.

scientific article published in August 2002

Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes

scientific article published on 20 November 2014

Recommendations for euthanasia of experimental animals: Part 1. DGXI of the European Commission.

scientific article

Recommendations for euthanasia of experimental animals: Part 2. DGXT of the European Commission

scientific article published on 01 January 1997

Record-keeping requirements of the Animals (Scientific Procedures) Act 1986 and how to meet them

scientific article published on 01 July 1987

Refinement of animal use--assessment and alleviation of pain and distress.

scientific article published on July 1994

Refinement of the use of food and fluid control as motivational tools for macaques used in behavioural neuroscience research: report of a Working Group of the NC3Rs

scientific article published on 22 September 2010

Renal scarring caused by vesicoureteric reflux and urinary infection: a study in pigs.

scientific article

Replacement, reduction and refinement.

scientific article

Reported analgesic and anaesthetic administration to non-human primates undergoing experimental surgical procedure: 2010-2015

scientific article published on 19 April 2018

Respiratory disease associated with parainfluenza Type I (Sendai) virus in a colony of marmosets (Callithrix jacchus).

scientific article published in April 1983

Restraint, anaesthesia and treatment of children's pets.

scientific article published in May 1983

Rodent analgesia: Assessment and therapeutics.

scientific article published on 23 December 2017

Scalp blood flow measured by the xenon clearance technique and transcutaneous PO2 in the fetal lamb

scientific article published on 01 December 1983

Skin ulceration associated with herpesvirus infection in cats ⬇️

scientific article published on April 7, 1979

Steady state glucose kinetics and their relation to plasma glucose concentration in the premature and full term neonatal piglet

scientific article published on 01 October 1981

Study of apoptosis and heat shock protein (HSP) expression in hepatocytes following radiofrequency ablation (RFA)

scientific article published on 22 June 2005

Sufentanil and medetomidine anaesthesia in the rat and its reversal with atipamezole and butorphanol.

scientific article published in July 2000

Sufentanil-medetomidine anaesthesia compared with fentanyl/fluanisone-midazolam is associated with fewer ventricular arrhythmias and death during experimental myocardial infarction in rats and limits infarct size following reperfusion.

scientific article published in January 2017

Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation

scientific article

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments).

scientific article published on January 2017

The analgesic effects of oral paracetamol in two strains of mice undergoing vasectomy.

scientific article

The assessment of depth of anaesthesia in animals and man

scientific article published on July 1, 1992

The assessment of post-vasectomy pain in mice using behaviour and the Mouse Grimace Scale

scientific article published in 2012

The conditioned place preference test for assessing welfare consequences and potential refinements in a mouse bladder cancer model

scientific article

The effects of buprenorphine, nalbuphine and butorphanol alone or following halothane anaesthesia on food and water consumption and locomotor movement in rats

scientific article published on July 1, 1992

The effects of surgical stimulus on the rat and the influence of analgesic treatment

scientific article published on 01 November 1993

The influence of buprenorphine or bupivacaine on the post-operative effects of laparotomy and bile-duct ligation in rats.

scientific article published in October 1993

The influence of pre-anaesthetic administration of buprenorphine on the anaesthetic effects of ketamine/medetomidine and pentobarbitone in rats and the consequences of repeated anaesthesia.

scientific article published in July 1999

The prognosis and treatment related to the gross appearance and laboratory characteristics of pathological thoracic fluids in the cat

scientific article published on 01 June 1978

The tissue-blood partition coefficient of iodoantipyrine in pig brain and its change with age.

scientific article published in June 1983

The use of a prostacyclin analog, iloprost, as an adjunct to pulmonary preservation with Euro-Collins solution ⬇️

scientific article published on March 1, 1990

The use of desflurane for neurosurgical procedures in rhesus macaque ( Macaca mulatta).

scientific article published in January 2017

The use of lignocaine-prilocaine local anaesthetic cream for pain-free venepuncture in laboratory animals.

scientific article published in April 1990

The use of non-steroidal anti-inflammatory drugs for the relief of pain in laboratory rodents and rabbits

scientific article published on October 1, 1992

The use of propofol and sevoflurane for surgical anaesthesia in New Zealand White rabbits.

scientific article published on 13 January 2010

Total body-glucose turnover in normal and intra-uterine growth-retarded neonatal piglets

scientific article published on 01 March 1981

Towards the computerized animal house: the Newcastle University Animal House Management System

scientific article published on 01 April 1986

Translational pain assessment: could natural animal models be the missing link?

scientific article

Use of animals in research

scientific article published on 01 June 1991

Use of oral buprenorphine ('buprenorphine jello') for postoperative analgesia in rats--a clinical trial

scientific article published on 01 April 1999

Using the mouse grimace scale and behaviour to assess pain in CBA mice following vasectomy.

scientific article published on August 2016

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