List of works - Bart Roep

A randomised, single-blind, placebo-controlled, dose-finding safety and tolerability study of the anti-CD3 monoclonal antibody otelixizumab in new-onset type 1 diabetes

scientific article published on 04 November 2020

A viral link for type 1 diabetes

scientific article published on 01 December 2019

An increased frequency of NK cell receptor and HLA-C group 1 combinations in early-onset type 1 diabetes ⬇️

scientific article published on September 10, 2011

Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes.

scientific article published on 27 February 2017

Beta cells under attack: toward a better understanding of type 1 diabetes immunopathology ⬇️

scientific article published on December 18, 2010

Clinical and preclinical immunology of type 1 diabetes ⬇️

scientific article published on 01 September 1998

Cloned T Cells from a Recent Onset IDDM Patient Reactive with Insulin B-chain ⬇️

scientific article published on April 1, 1998

Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells.

scientific article

Genetic correlates of early accelerated infant growth associated with juvenile-onset type 1 diabetes ⬇️

scientific article published on September 20, 2011

HLA-DR binding analysis of peptides from islet antigens in IDDM ⬇️

scientific article published on 01 October 1998

Heterogeneity of circulating CD8 T-cells specific to islet, neo-antigen and virus in patients with type 1 diabetes mellitus

scientific article published in PLoS ONE

Immune Monitoring of Islet and Pancreas Transplant Recipients ⬇️

scientific article published on October 1, 2013

Immunotherapy for type 1 diabetes mellitus (DM1)

scientific article published on 01 January 2012

Islet antigen-specific T cell clones in autoimmune diabetes: from mice to men ⬇️

scientific article published on September 1, 1997

Islet stress, degradation and autoimmunity

scientific article published on 01 September 2018

Minimal information about T cell assays: the process of reaching the community of T cell immunologists in cancer and beyond ⬇️

scientific article published on November 16, 2010

Molecular mimicry in diabetes mellitus: the homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD 65 is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule ⬇️

scientific article published on January 1, 1998

New hope for immune intervention therapy in type 1 diabetes ⬇️

scientific article published on June 28, 2011

No extreme genetic risk for type 1 diabetes among DR3/4‐DQ8 siblings sharing both extended HLA haplotypes with their diabetic proband ⬇️

scientific article published on 01 April 2011

Persistent C-peptide is associated with reduced hypoglycaemia but not HbA1c in adults with longstanding Type 1 diabetes: evidence for lack of intensive treatment in UK clinical practice?

scientific article published on 27 June 2019

Regulatory Multitasking of Tolerogenic Dendritic Cells – Lessons Taken from Vitamin D3-Treated Tolerogenic Dendritic Cells ⬇️

scientific article published on May 14, 2013

Th1-like Cytokine Production Profile and Individual Specific Alterations in TCRBV-gene Usage of T Cells from Newly Diagnosed Type 1 Diabetes Patients after Stimulation with β-cell Antigens ⬇️

scientific article published on 01 December 1997

The identification of CD4 + T cell epitopes with dedicated synthetic peptide libraries ⬇️

scientific article published on September 16, 1997

Type 1 diabetes mellitus as a disease of the β-cell (do not blame the immune system?)

scientific article published on 08 December 2020

β-Cells, Autoimmunity, and the Innate Immune System: “un Ménage á Trois”? ⬇️

scientific article published on June 1, 2013

List of works by Bart Roep