List of works - Mark S Smeltzer

Antibiotic-loaded phosphatidylcholine inhibits staphylococcal bone infection.

scientific article published on 18 August 2016

Biofilm-Infected Intracerebroventricular Shunts Elicit Inflammation within the Central Nervous System ⬇️

scientific article published on July 2, 2012

Blended Chitosan Paste for Infection Prevention: Preliminary and Preclinical Evaluations

scientific article published on 17 January 2017

Characterization of Staphylococcus aureus SarA binding sites

scientific article

Characterization of a rabbit model of staphylococcal osteomyelitis

scientific article published on 01 May 1997

Characterization of local delivery with amphotericin B and vancomycin from modified chitosan sponges and functional biofilm prevention evaluation.

scientific article published on 20 November 2014

Characterization of the SarA virulence gene regulator of Staphylococcus aureus.

scientific article

Chitosan coating to enhance the therapeutic efficacy of calcium sulfate-based antibiotic therapy in the treatment of chronic osteomyelitis

scientific article

Ciprofloxacin and Rifampin Dual Antibiotic-Loaded Biopolymer Chitosan Sponge for Bacterial Inhibition.

scientific article published in March 2018

Comparative evaluation of use of cna, fnbA, fnbB, and hlb for genomic fingerprinting in the epidemiological typing of Staphylococcus aureus ⬇️

scientific article published on October 1, 1997

Comparative genomics of Staphylococcus aureus musculoskeletal isolates.

scientific article

Comparative impact of diverse regulatory loci on Staphylococcus aureus biofilm formation

scientific article published on 21 March 2015

Comparison of the enzyme-linked immunosorbent assay and complement fixation test for detecting Brucella ovis antibodies in sheep

scientific article published on 01 November 1983

Could targeted, antibiotic-loaded gold nanoconstructs be a new magic bullet to fight infection?

scientific article published on 16 August 2016

Detecting bacterial colonization of implanted orthopaedic devices by ultrasonication.

scientific article

Development of a novel, highly quantitative in vivo model for the study of biofilm-impaired cutaneous wound healing.

scientific article

Differential RNA regulation by staphylococcal enterotoxins A and B in murine macrophages

scientific article published on 01 April 1994

Ellagic acid derivatives from Rubus ulmifolius inhibit Staphylococcus aureus biofilm formation and improve response to antibiotics

scientific article

Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation

scientific article

Evaluation of Antibiotics Active against Methicillin-Resistant Staphylococcus aureus Based on Activity in an Established Biofilm

scientific article published on 11 July 2016

Evaluation of a chitosan-polyethylene glycol paste as a local antibiotic delivery device.

scientific article published on 18 February 2017

Evaluation of dynamic [18F]-FDG-PET imaging for the detection of acute post-surgical bone infection

scientific article

Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis

scientific article published on 26 November 2019

Factors affecting the collagen binding capacity of Staphylococcus aureus.

scientific article

Factors contributing to the biofilm-deficient phenotype of Staphylococcus aureus sarA mutants

scientific article

Functional analysis of the Staphylococcus aureus collagen adhesin B domain

scientific article

Genome-scale transcriptional profiling in Staphylococcus aureus : bringing order out of chaos.

scientific article published on May 2009

Global gene expression in Staphylococcus aureus biofilms.

scientific article

Hyaluronidase expression and biofilm involvement in Staphylococcus aureus UAMS-1 and its sarA, agr and sarA agr regulatory mutants ⬇️

scientific article published on 07 February 2013

Identification and characterization of msa (SA1233), a gene involved in expression of SarA and several virulence factors in Staphylococcus aureus

scientific article published on 01 September 2006

Impact of Staphylococcus aureus regulatory mutations that modulate biofilm formation in the USA300 strain LAC on virulence in a murine bacteremia model.

scientific article published on 14 September 2017

Impact of extracellular nuclease production on the biofilm phenotype of Staphylococcus aureus under in vitro and in vivo conditions.

scientific article

Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants.

scientific article

Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus.

scientific article published on 27 June 2016

Impact of sarA on antibiotic susceptibility of Staphylococcus aureus in a catheter-associated in vitro model of biofilm formation

scientific article published on 16 March 2009

Impact of sarA on daptomycin susceptibility of Staphylococcus aureus biofilms in vivo

scientific article published on 03 August 2009

Impact of the functional status of saeRS on in vivo phenotypes of Staphylococcus aureus sarA mutants

scientific article

In vivo magnetic enrichment, photoacoustic diagnosis, and photothermal purging of infected blood using multifunctional gold and magnetic nanoparticles

scientific article

Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections

scientific article published on January 2006

Introduction to the special issue on thermal therapy and infectious diseases.

scientific article published in March 2018

Investigation of biofilm formation in clinical isolates of Staphylococcus aureus

scientific article

Investigation of biofilm formation in clinical isolates of Staphylococcus aureus.

scientific article

Is aseptic loosening truly aseptic?

scientific article

Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome

scientific article published on 27 September 2018

Local Delivery of Amikacin and Vancomycin from Chitosan Sponges Prevent Polymicrobial Implant-Associated Biofilm

scientific article published on 01 March 2018

Localization of a chromosomal mutation affecting expression of extracellular lipase in Staphylococcus aureus ⬇️

scientific article published on June 1, 1992

Management of acute hematogenous osteomyelitis in children

scientific article published on February 2010

Modulation of eDNA release and degradation affects Staphylococcus aureus biofilm maturation

scientific article

Molecular pathogenesis of staphylcoccal osteomyelitis

scientific article

Multiplex PCR protocol for the diagnosis of staphylococcal infection.

scientific article

Mutation of traP in Staphylococcus aureus has no impact on expression of agr or biofilm formation

scientific article

Novel Antibiotic-loaded Point-of-care Implant Coating Inhibits Biofilm.

scientific article published on July 2015

Novel Bone-Targeting Agent for Enhanced Delivery of Vancomycin to Bone

scientific article published on 14 December 2015

Novel Linear Lipopeptide Paenipeptins with Potential for Eradicating Biofilms and Sensitizing Gram-Negative Bacteria to Rifampicin and Clarithromycin.

scientific article

Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus

scientific article

Optimized elution of daptomycin from polymethylmethacrylate beads.

scientific article published on 27 October 2008

Phenotypic characterization of xpr, a global regulator of extracellular virulence factors in Staphylococcus aureus.

scientific article

Phosphatidylcholine Coatings Deliver Local Antimicrobials and Reduce Infection in a Murine Model: A Preliminary Study.

scientific article published on 03 January 2017

Photothermal nanotherapeutics and nanodiagnostics for selective killing of bacteria targeted with gold nanoparticles

scientific article

Polymicrobial Biofilm Inhibition Effects of Acetate-Buffered Chitosan Sponge Delivery Device.

scientific article

Prevalence and chromosomal map location of Staphylococcus aureus adhesin genes

scientific article published on 01 September 1997

Quercus cerris extracts limit Staphylococcus aureus biofilm formation

scientific article

Regulatory Mutations Impacting Antibiotic Susceptibility in an Established Staphylococcus aureus Biofilm

scientific article published on 11 January 2016

Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis.

scientific article

SaeRS-dependent inhibition of biofilm formation in Staphylococcus aureus Newman

scientific article

Small molecule inhibitors of Staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis

scientific article

Staphylococcus aureus Pathogenesis: The Importance of Reduced Cytotoxicity

scientific article published on 19 July 2016

Staphylococcus aureus SarA is a regulatory protein responsive to redox and pH that can support bacteriophage lambda integrase-mediated excision/recombination

scientific article

Staphylococcus aureus biofilm metabolism and the influence of arginine on polysaccharide intercellular adhesin synthesis, biofilm formation, and pathogenesis.

scientific article

Staphylococcus aureus evades the extracellular antimicrobial activity of mast cells by promoting its own uptake

scientific article published on 8 June 2011

Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation

scientific article

Strain-dependent differences in the regulatory roles of sarA and agr in Staphylococcus aureus.

scientific article

Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs.

scientific article published on 10 February 2016

The Staphylococcal accessory regulator (sar) represses transcription of the Staphylococcus aureus collagen adhesin gene (cna) in an agr-independent manner

scientific article published on 01 July 1999

The Staphylococcus aureus collagen adhesin-encoding gene (cna) is within a discrete genetic element.

scientific article published in September 1997

The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus.

scholarly article

The effect of lysogeny on the genomic organization of Staphylococcus aureus

scientific article published on 01 January 1994

The staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates the mRNA turnover properties of late-exponential and stationary phase Staphylococcus aureus cells.

scientific article

The treatment of experimental osteomyelitis by surgical debridement and the implantation of calcium sulfate tobramycin pellets.

scientific article published in July 2002

Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390.

scientific article published in October 2006

Transcriptional regulation of the Staphylococcus aureus collagen adhesion gene, cna.

scientific article published on April 1997

Versatility of Targeted Antibiotic-loaded Gold Nanoconstructs for the Treatment of Biofilm-associated Bacterial Infections.

scientific article

XerC Contributes to Diverse Forms of Staphylococcus aureus Infection via agr-Dependent and agr-Independent Pathways

scientific article published on 8 February 2016

Xylitol and glycine fillers increase permeability of PMMA to enhance elution of daptomycin.

scientific article published in October 2006

saeRS and sarA act synergistically to repress protease production and promote biofilm formation in Staphylococcus aureus

scientific article

sarA-mediated repression of protease production plays a key role in the pathogenesis of Staphylococcus aureus USA300 isolates.

scientific article

List of works by Mark S Smeltzer

Antibiotic-loaded phosphatidylcholine inhibits staphylococcal bone infection.

Biofilm-Infected Intracerebroventricular Shunts Elicit Inflammation within the Central Nervous System ⬇️

Blended Chitosan Paste for Infection Prevention: Preliminary and Preclinical Evaluations

Characterization of Staphylococcus aureus SarA binding sites

Characterization of a rabbit model of staphylococcal osteomyelitis

Characterization of local delivery with amphotericin B and vancomycin from modified chitosan sponges and functional biofilm prevention evaluation.

Characterization of the SarA virulence gene regulator of Staphylococcus aureus.

Chitosan coating to enhance the therapeutic efficacy of calcium sulfate-based antibiotic therapy in the treatment of chronic osteomyelitis

Ciprofloxacin and Rifampin Dual Antibiotic-Loaded Biopolymer Chitosan Sponge for Bacterial Inhibition.

Comparative evaluation of use of cna, fnbA, fnbB, and hlb for genomic fingerprinting in the epidemiological typing of Staphylococcus aureus ⬇️

Comparative genomics of Staphylococcus aureus musculoskeletal isolates.

Comparative impact of diverse regulatory loci on Staphylococcus aureus biofilm formation

Comparison of the enzyme-linked immunosorbent assay and complement fixation test for detecting Brucella ovis antibodies in sheep

Could targeted, antibiotic-loaded gold nanoconstructs be a new magic bullet to fight infection?

Detecting bacterial colonization of implanted orthopaedic devices by ultrasonication.

Development of a novel, highly quantitative in vivo model for the study of biofilm-impaired cutaneous wound healing.

Differential RNA regulation by staphylococcal enterotoxins A and B in murine macrophages

Ellagic acid derivatives from Rubus ulmifolius inhibit Staphylococcus aureus biofilm formation and improve response to antibiotics

Epistatic relationships between sarA and agr in Staphylococcus aureus biofilm formation

Evaluation of Antibiotics Active against Methicillin-Resistant Staphylococcus aureus Based on Activity in an Established Biofilm

Evaluation of a chitosan-polyethylene glycol paste as a local antibiotic delivery device.

Evaluation of dynamic [18F]-FDG-PET imaging for the detection of acute post-surgical bone infection

Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphylococcus aureus Osteomyelitis

Factors affecting the collagen binding capacity of Staphylococcus aureus.

Factors contributing to the biofilm-deficient phenotype of Staphylococcus aureus sarA mutants

Functional analysis of the Staphylococcus aureus collagen adhesin B domain

Genome-scale transcriptional profiling in Staphylococcus aureus : bringing order out of chaos.

Global gene expression in Staphylococcus aureus biofilms.

Hyaluronidase expression and biofilm involvement in Staphylococcus aureus UAMS-1 and its sarA, agr and sarA agr regulatory mutants ⬇️

Identification and characterization of msa (SA1233), a gene involved in expression of SarA and several virulence factors in Staphylococcus aureus

Impact of Staphylococcus aureus regulatory mutations that modulate biofilm formation in the USA300 strain LAC on virulence in a murine bacteremia model.

Impact of extracellular nuclease production on the biofilm phenotype of Staphylococcus aureus under in vitro and in vivo conditions.

Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants.

Impact of sarA and Phenol-Soluble Modulins on the Pathogenesis of Osteomyelitis in Diverse Clinical Isolates of Staphylococcus aureus.

Impact of sarA on antibiotic susceptibility of Staphylococcus aureus in a catheter-associated in vitro model of biofilm formation

Impact of sarA on daptomycin susceptibility of Staphylococcus aureus biofilms in vivo

Impact of the functional status of saeRS on in vivo phenotypes of Staphylococcus aureus sarA mutants

In vivo magnetic enrichment, photoacoustic diagnosis, and photothermal purging of infected blood using multifunctional gold and magnetic nanoparticles

Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections

Introduction to the special issue on thermal therapy and infectious diseases.

Investigation of biofilm formation in clinical isolates of Staphylococcus aureus

Investigation of biofilm formation in clinical isolates of Staphylococcus aureus.

Is aseptic loosening truly aseptic?

Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome

Local Delivery of Amikacin and Vancomycin from Chitosan Sponges Prevent Polymicrobial Implant-Associated Biofilm

Localization of a chromosomal mutation affecting expression of extracellular lipase in Staphylococcus aureus ⬇️

Management of acute hematogenous osteomyelitis in children

Modulation of eDNA release and degradation affects Staphylococcus aureus biofilm maturation

Molecular pathogenesis of staphylcoccal osteomyelitis

Multiplex PCR protocol for the diagnosis of staphylococcal infection.

Mutation of traP in Staphylococcus aureus has no impact on expression of agr or biofilm formation

Novel Antibiotic-loaded Point-of-care Implant Coating Inhibits Biofilm.

Novel Bone-Targeting Agent for Enhanced Delivery of Vancomycin to Bone

Novel Linear Lipopeptide Paenipeptins with Potential for Eradicating Biofilms and Sensitizing Gram-Negative Bacteria to Rifampicin and Clarithromycin.

Nuclease modulates biofilm formation in community-associated methicillin-resistant Staphylococcus aureus

Optimized elution of daptomycin from polymethylmethacrylate beads.

Phenotypic characterization of xpr, a global regulator of extracellular virulence factors in Staphylococcus aureus.

Phosphatidylcholine Coatings Deliver Local Antimicrobials and Reduce Infection in a Murine Model: A Preliminary Study.

Photothermal nanotherapeutics and nanodiagnostics for selective killing of bacteria targeted with gold nanoparticles

Polymicrobial Biofilm Inhibition Effects of Acetate-Buffered Chitosan Sponge Delivery Device.

Prevalence and chromosomal map location of Staphylococcus aureus adhesin genes

Quercus cerris extracts limit Staphylococcus aureus biofilm formation

Regulatory Mutations Impacting Antibiotic Susceptibility in an Established Staphylococcus aureus Biofilm

Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis.

SaeRS-dependent inhibition of biofilm formation in Staphylococcus aureus Newman

Small molecule inhibitors of Staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis

Staphylococcus aureus Pathogenesis: The Importance of Reduced Cytotoxicity

Staphylococcus aureus SarA is a regulatory protein responsive to redox and pH that can support bacteriophage lambda integrase-mediated excision/recombination

Staphylococcus aureus biofilm metabolism and the influence of arginine on polysaccharide intercellular adhesin synthesis, biofilm formation, and pathogenesis.

Staphylococcus aureus evades the extracellular antimicrobial activity of mast cells by promoting its own uptake

Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation

Strain-dependent differences in the regulatory roles of sarA and agr in Staphylococcus aureus.

Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs.

The Staphylococcal accessory regulator (sar) represses transcription of the Staphylococcus aureus collagen adhesin gene (cna) in an agr-independent manner

The Staphylococcus aureus collagen adhesin-encoding gene (cna) is within a discrete genetic element.

The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus.

The effect of lysogeny on the genomic organization of Staphylococcus aureus

The staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates the mRNA turnover properties of late-exponential and stationary phase Staphylococcus aureus cells.

The treatment of experimental osteomyelitis by surgical debridement and the implantation of calcium sulfate tobramycin pellets.