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List of works by Gerald J Atkins

1,25-Dihydroxyvitamin D3 and extracellular calcium promote mineral deposition via NPP1 activity in a mature osteoblast cell line MLO-A5.

scientific article published on 6 June 2015

1α,25-dihydroxyvitamin D3 stimulates human SOST gene expression and sclerostin secretion

scientific article

A New Approach to Surgical Management of Tibial Plateau Fractures

scientific article published on 26 February 2020

A Role for the Calcitonin Receptor to Limit Bone Loss During Lactation in Female Mice by Inhibiting Osteocytic Osteolysis.

scientific article

Absence of vitamin D receptor in mature osteoclasts results in altered osteoclastic activity and bone loss.

scientific article published on 28 October 2017

Adoptive transfer of ex vivo expanded Vγ9Vδ2 T cells in combination with zoledronic acid inhibits cancer growth and limits osteolysis in a murine model of osteolytic breast cancer

scientific article published on 16 November 2016

An update on primary hip osteoarthritis including altered Wnt and TGF-β associated gene expression from the bony component of the disease

scientific article published on 08 October 2011

Analysis of vitamin D metabolism gene expression in human bone: evidence for autocrine control of bone remodelling

scientific article published on 10 October 2013

Anodized 3D-printed titanium implants with dual micro- and nano-scale topography promote interaction with human osteoblasts and osteocyte-like cells.

scientific article published on 7 December 2016

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide (TH-302) in osteolytic breast cancer murine models

scientific article published on 9 January 2016

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma

scientific article published on 10 August 2017

Assigning trabecular bone material properties in finite element models simulating the pelvis before and after the development of peri-prosthetic osteolytic lesions

scientific article published in 2022

Biocompatible polymer coating of titania nanotube arrays for improved drug elution and osteoblast adhesion

scientific article published on 08 September 2011

Biomimetic hydroxyapatite coating on glass coverslips for the assay of osteoclast activity in vitro

scientific article published on 4 March 2009

Both ligand and VDR expression levels critically determine the effect of 1α,25-dihydroxyvitamin-D3 on osteoblast differentiation.

scientific article published on 5 September 2017

Bril: a novel bone-specific modulator of mineralization

scientific journal article

Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice

scientific article

Changes in osteocyte density correspond with changes in osteoblast and osteoclast activity in an osteoporotic sheep model

scientific article published on 31 May 2011

Characterization of drug-release kinetics in trabecular bone from titania nanotube implants.

scientific article

Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis.

scientific article published on June 2002

Circulating levels of TWEAK correlate with bone erosion in multiple myeloma patients

scientific article published on 12 April 2010

Comparison of the biological effects of exogenous and endogenous 1,25-dihydroxyvitamin D3 on the mature osteoblast cell line MLO-A5.

scientific article published on 03 March 2016

Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation.

scientific article

Critical molecular regulators, histomorphometric indices and their correlations in the trabecular bone in primary hip osteoarthritis

scientific article published on 03 August 2010

Current concepts of osteomyelitis: from pathological mechanisms to advanced research methods

scientific article published on 16 March 2020

Does Apo2L/TRAIL play any physiologic role in osteoclastogenesis?

scientific article published on 01 June 2008

Drug diffusion, integration, and stability of nanoengineered drug-releasing implants in bone ex-vivo.

scientific article published on 20 October 2015

Drug-releasing nano-engineered titanium implants: therapeutic efficacy in 3D cell culture model, controlled release and stability

scientific article published on 21 July 2016

Early response of the human SOST gene to stimulation by 1α,25-dihydroxyvitamin D3.

scientific article published on 9 December 2015

Elevated Serum 25-Hydroxyvitamin D Levels Are Associated with Improved Bone Formation and Micro-Structural Measures in Elderly Hip Fracture Patients

scientific article published on 15 November 2019

Evidence for Gender-Specific Bone Loss Mechanisms in Periprosthetic Osteolysis

scientific article published on 24 December 2019

Evidence for altered osteoclastogenesis in splenocyte cultures from Cyp27b1 knockout mice

scientific article published on 27 November 2015

Evidence for altered osteoclastogenesis in splenocyte cultures from VDR knockout mice.

scientific article

Evidence that osteocyte perilacunar remodelling contributes to polyethylene wear particle induced osteolysis.

scientific article published on 18 January 2016

Expression of fibrillins and other microfibril-associated proteins in human bone and osteoblast-like cells

scientific article published on 01 July 2000

Expression of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor, fibroblast growth factor-inducible 14 protein (Fn14), in healthy tissues and in tissues affected by periodontitis

scientific article published on 10 June 2010

Extracellular phosphate modulates the effect of 1α,25-dihydroxy vitamin D3 (1,25D) on osteocyte like cells

scientific article published on 09 October 2012

First Australian report of vitamin D-dependent rickets type I

scientific article published on 01 October 2014

Human osteoblasts are resistant to Apo2L/TRAIL-mediated apoptosis

scientific article published on 01 October 2002

Human osteocyte expression of Nerve Growth Factor: The effect of Pentosan Polysulphate Sodium (PPS) and implications for pain associated with knee osteoarthritis

scientific article published on 26 September 2019

Human trabecular bone-derived osteoblasts support human osteoclast formation in vitro in a defined, serum-free medium.

scientific article

Hypoxia-activated pro-drug TH-302 exhibits potent tumor suppressive activity and cooperates with chemotherapy against osteosarcoma.

scientific article

Impaction bone grafting has potential as an adjunct to the surgical stabilisation of osteoporotic tibial plateau fractures: Early results of a case series.

scientific article

Isolation of osteocytes from human trabecular bone.

scientific article published on 22 April 2016

Metabolism of vitamin D3 in human osteoblasts: evidence for autocrine and paracrine activities of 1 alpha,25-dihydroxyvitamin D3.

scientific article published on 2 March 2007

Modulation of osteoclastic migration by metabolism of 25OH-vitamin D3.

scientific article published on 16 September 2012

Novel Insights into Staphylococcus aureus Deep Bone Infections: the Involvement of Osteocytes.

scientific article published on 24 April 2018

Novel targets of vitamin D activity in bone: action of the vitamin D receptor in osteoblasts, osteocytes and osteoclasts

scientific article published on December 2013

Osteoblast-chondrocyte interactions in osteoarthritis

scientific article

Osteoclastic metabolism of 25(OH)-vitamin D3: a potential mechanism for optimization of bone resorption

scientific article

Osteocyte regulation of bone mineral: a little give and take.

scientific article published on August 2012

Osteocytes respond to particles of clinically-relevant conventional and cross-linked polyethylene and metal alloys by up-regulation of resorptive and inflammatory pathways

scientific article published on 25 January 2019

Osteocytes: The master cells in bone remodelling

scientific article published on 26 February 2016

Osteoprotegerin (OPG) is localized to the Weibel-Palade bodies of human vascular endothelial cells and is physically associated with von Willebrand factor

scientific article published on 01 August 2005

Osteoprotegerin and receptor activator of nuclear factor kappaB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint.

scientific article

Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls.

scientific article published in January 2003

Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone

scientific article published on 01 April 2001

Periprosthetic osteolysis after total hip replacement: molecular pathology and clinical management.

scientific article published on 15 October 2013

Peroxidase Enzymes Regulate Collagen Biosynthesis and Matrix Mineralization by Cultured Human Osteoblasts

scientific article published on 7 December 2015

Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.

scientific article published on 8 November 2016

Pharmacologic inhibition of bone resorption prevents cancer-induced osteolysis but enhances soft tissue metastasis in a mouse model of osteolytic breast cancer

scientific article

Polyethylene particles stimulate expression of ITAM-related molecules in peri-implant tissues and when stimulating osteoclastogenesis in vitro

scientific article published on 30 April 2012

Postoperative weight bearing and patient reported outcomes at one year following tibial plateau fractures

scientific article published on 17 May 2017

Primary human osteoblasts grow into porous tantalum and maintain an osteoblastic phenotype.

scientific article

Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts

scientific article published on August 2009

RANK Expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone

scientific article published on 01 September 2006

RANKL expression is related to the differentiation state of human osteoblasts.

scientific article

Recombinant sclerostin antagonises effects of ex vivo mechanical loading in trabecular bone and increases osteocyte lacunar size

scientific article published on 4 October 2017

Regulation of FGF23 expression in IDG-SW3 osteocytes and human bone by pro-inflammatory stimuli.

scientific article

Relationship between serum RANKL and RANKL in bone

scientific article (publication date: October 2011)

Reversal of established bone pathology in MPS VII mice following lentiviral-mediated gene therapy

scientific article published on 24 September 2016

SaOS2 Osteosarcoma cells as an in vitro model for studying the transition of human osteoblasts to osteocytes.

scientific article

Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2.

scientific article published on December 2013

Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway

scientific article

Semaphorin-3a, neuropilin-1 and plexin-A1 in prosthetic-particle induced bone loss

scientific article published on 18 November 2015

Sex-related differences in the skeletal phenotype of aged vitamin D receptor global knockout mice

scientific article published on 9 December 2015

Skeletal characterization of an osteoblast-specific vitamin D receptor transgenic (ObVDR-B6) mouse model.

scientific article published on 4 September 2015

TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis.

scientific article

TWEAK and TNF regulation of sclerostin: a novel pathway for the regulation of bone remodelling

scientific article

TWEAK is a novel arthritogenic mediator

scientific article published on 01 August 2006

The Late Osteoblast/Preosteocyte Cell Line MLO-A5 Displays Mesenchymal Lineage Plasticity and

scientific article published on 17 January 2019

The local production of 1,25(OH)2D3 promotes osteoblast and osteocyte maturation

scientific article published on 12 October 2013

The metabolism of 25-(OH)vitamin D3 by osteoclasts and their precursors regulates the differentiation of osteoclasts.

scientific article published on 19 March 2010

The nitrogen-containing bisphosphonate, zoledronic acid, increases mineralisation of human bone-derived cells in vitro.

scientific article published on January 2004

The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation.

scientific article published on 29 August 2013

The pleiotropic effects of vitamin D in bone

scientific article published on 05 September 2012

The proliferation and phenotypic expression of human osteoblasts on tantalum metal.

scientific article published in May 2004

The ratio of messenger RNA levels of receptor activator of nuclear factor kappaB ligand to osteoprotegerin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis

scientific article published on 01 June 2001

The skeleton as an intracrine organ for vitamin D metabolism

scientific article published on 07 July 2008

Time dependent loss of trabecular bone in human tibial plateau fractures

scientific article published on 13 July 2018

Vitamin D metabolism within bone cells: effects on bone structure and strength

scientific article published on June 2011

Vitamin D receptor overexpression in osteoblasts and osteocytes prevents bone loss during vitamin D-deficiency.

scientific article published on 13 January 2014

Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms.

scientific article published on 12 August 2009

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