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List of works by Peter Leung

<i>TOX3</i> Promotes Ovarian Estrogen Synthesis: An RNA-Sequencing and Network Study

scientific article published on 01 January 2020

A mechanism for the intraovarian inhibitory action of estrogen on androgen production

scientific article published on 01 November 1979

A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.

scientific article published on 21 February 2012

ALK2/ALK3-BMPR2/ACVR2A Mediate BMP2-Induced Downregulation of Pentraxin 3 Expression in Human Granulosa-Lutein Cells.

scientific article

ALK4-SMAD2/3-SMAD4 signaling mediates the activin A-induced suppression of PTX3 in human granulosa-lutein cells

scientific article published on 08 June 2019

AP-1 Transcription Factors c-FOS and c-JUN Mediate GnRH-Induced Cadherin-11 Expression and Trophoblast Cell Invasion

scientific article

Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial

scientific article published in July 2018

Activin A Increases Human Trophoblast Invasion by Inducing SNAIL-Mediated MMP2 Up-Regulation Through ALK4.

scientific article published on 25 August 2015

Activin A increases human trophoblast invasion by upregulating integrin β1 through ALK4

scientific article published on 23 November 2020

Activin A promotes ovarian cancer cell migration by suppressing E-cadherin expression

scientific article published on 20 June 2019

Activin A upregulates PTGS2 expression and increases PGE2 production in human granulosa-lutein cells.

scientific article published on 13 September 2016

Activin A, B and AB decrease progesterone production by down-regulating StAR in human granulosa cells.

scientific article

Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin.

scientific article

Activin A-induced increase in LOX activity in human granulosa-lutein cells is mediated by CTGF.

scientific article

Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling

scientific article published on 28 August 2015

Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling.

scientific article published on 19 May 2016

Activin receptor signaling.

scientific article published in June 2004

Activin-A up-regulates type I activin receptor mRNA levels in human immortalized extravillous trophoblast cells

scientific article

Acute stimulation of human chorionic gonadotropin secretion by recombinant human activin-A in first trimester human trophoblast

scientific article published on 01 July 1993

Adenosine 5'-triphosphate activates nuclear translocation of mitogen-activated protein kinases leading to the induction of early growth response 1 and raf expression in human granulosa-luteal cells.

scientific article published in October 2004

Adenosine triphosphate activates mitogen-activated protein kinase in pre-neoplastic and neoplastic ovarian surface epithelial cells.

scientific article published on January 2003

Alternative splicing of the androgen receptor in polycystic ovary syndrome

scientific article

Amphiregulin induces human ovarian cancer cell invasion by down-regulating E-cadherin expression

scientific article published on 23 September 2014

An activator protein 1-like motif mediates 17beta-estradiol repression of gonadotropin-releasing hormone receptor promoter via an estrogen receptor alpha-dependent mechanism in ovarian and breast cancer cells.

scientific article published on 28 August 2003

An intraovarian inhibitory action of estrogen on androgen production in vivo

scientific article published on 01 October 1978

Androgenic alteration in pathways of C19-steroid metabolism by cultured rat granulosa cells.

scientific article published on June 1983

Antimüllerian hormone inhibits follicle-stimulating hormone-induced adenylyl cyclase activation, aromatase expression, and estradiol production in human granulosa-lutein cells ⬇️

scientific article published on May 10, 2013

Arachidonic acid and cell signalling in the ovary and placenta.

scientific article published on January 1993

Arachidonic acid as a stimulatory mediator of luteinizing hormone-releasing hormone action in the rat ovary.

scientific article published on April 1989

Autocrine role of gonadotropin-releasing hormone and its receptor in ovarian cancer cell growth

scientific article published on 01 December 2000

BMP15 suppresses progesterone production by down-regulating StAR via ALK3 in human granulosa cells.

scientific article

BMP4 and BMP7 Suppress StAR and Progesterone Production via ALK3 and SMAD1/5/8-SMAD4 in Human Granulosa-Lutein Cells

scientific article published on 24 August 2015

BMP6 down-regulates GDNF expression through SMAD1/5 and ERK1/2 signaling pathways in human granulosa-lutein cells.

scientific article

BMP6 increases TGF-β1 production by up-regulating furin expression in human granulosa-lutein cells

scientific article published on 08 January 2019

Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells.

scientific article published on 22 February 2016

Biology and physiology of Calbindin-D9k in female reproductive tissues: involvement of steroids and endocrine disruptors

scientific article

Bone Morphogenetic Protein 2 Promotes Human Trophoblast Cell Invasion by Inducing Activin A Production

scientific article published on 01 July 2018

Bone morphogenetic protein 2 increases lysyl oxidase activity via up-regulation of snail in human granulosa-lutein cells

scientific article published on 12 October 2018

Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling.

scientific article published on 7 February 2018

Bone morphogenetic protein 2 regulates cell-cell communication by down-regulating connexin43 expression in luteinized human granulosa cells

scientific article published on 16 December 2016

Bone morphogenetic protein 6 affects cell-cell communication by altering the expression of Connexin43 in human granulosa-lutein cells

scientific article published on 18 August 2019

CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells.

scientific article

COX2 and PGE2 mediate EGF-induced E-cadherin-independent human ovarian cancer cell invasion.

scientific article

Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer.

scientific article

Calbindin-D9k gene expression during pregnancy and lactation in the rat

scientific article published on 01 October 1992

Calbindin-D9k gene expression during the perinatal period in the rat: correlation to estrogen receptor expression in uterus

scientific article published on 01 November 1993

Calbindin-D9k mRNA is tightly regulated during the estrous cycle in the rat uterus

scientific article published on 01 July 1992

Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38.

scientific article

Cell motility and spreading are suppressed by HOXA4 in ovarian cancer cells: possible involvement of beta1 integrin.

scientific article

Cellular localization of gonadotropin-releasing hormone (GnRH) I and GnRH II in first-trimester human placenta and decidua

scientific article (publication date: March 2004)

Changes with age in aromatization of testosterone in immature female rats

scientific article published on December 1, 1978

Cloning of the porcine Calbindin-D9k complementary deoxyribonucleic acid by anchored polymerase chain reaction technique.

scientific article

Coexpression of hepatocyte growth factor-Met: an early step in ovarian carcinogenesis?

scientific article published on 01 March 2001

Complex regulation of Calbindin-D(9k) in the mouse placenta and extra-embryonic membrane during mid- and late pregnancy.

scientific article published in February 2004

Connective tissue growth factor mediates TGF-β1-induced low-grade serous ovarian tumor cell apoptosis

scientific article

Connective tissue growth factor mediates growth differentiation factor 8-induced increase of lysyl oxidase activity in human granulosa-lutein cells.

scientific article published on 5 July 2016

Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: influence of family history of ovarian cancer

scientific article published on 01 April 1999

Cytosolic free Ca2+ in human syncytiotrophoblast cells increased by gonadotropin-releasing hormone

scientific article published on 01 November 1993

Cytosolic free calcium increased by prostaglandin F2 alpha (PGF2 alpha), gonadotropin-releasing hormone, and angiotensin II in rat granulosa cells and PGF2 alpha in human granulosa cells.

scientific article published on April 1992

Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure.

scientific article published on 30 March 2018

Detection of mRNA expression of gonadotropin-releasing hormone and its receptor in normal and neoplastic rat prostates

scientific article published on 01 December 2001

Differential Role of PR-A and -B Isoforms in Transcription Regulation of Human GnRH Receptor Gene ⬇️

scientific article published on December 1, 2001

Differential activation of noncanonical SMAD2/SMAD3 signaling by bone morphogenetic proteins causes disproportionate induction of hyaluronan production in immortalized human granulosa cells

scientific article published on 15 March 2016

Differential effects of 8-bromo-cyclic AMP on human chorionic gonadotropin (hCG), progesterone and estrogen production by term placental cells.

scientific article

Differential effects of cellular fibronectin and plasma fibronectin on ovarian cancer cell adhesion, migration, and invasion ⬇️

scientific article published on March 1, 2003

Differential effects of central adrenoceptor agonists on luteinizing hormone release

scientific article published on 01 March 1982

Differential effects of interleukin-1β and transforming growth factor-β1 on the expression of the inflammation-associated protein, ADAMTS-1, in human decidual stromal cells in vitro

scientific article published on 04 May 2006

Differential expression of human gonadotropin-releasing hormone receptor gene in pituitary and ovarian cells.

scientific article published on April 2000

Differential regulation of two forms of gonadotropin-releasing hormone messenger ribonucleic acid by gonadotropins in human immortalized ovarian surface epithelium and ovarian cancer cells.

scientific article

Differential role of gonadotropin-releasing hormone on human ovarian epithelial cancer cell invasion.

scientific article

Differential role of progesterone receptor isoforms in the transcriptional regulation of human gonadotropin-releasing hormone I (GnRH I) receptor, GnRH I, and GnRH II

scientific article

Differential role of protein kinase C in the action of luteinizing hormone-releasing hormone on hormone production in rat ovarian cells

scientific article published on 01 April 1989

Divergent differentiation of rat adrenocortical cells is associated with an interruption of angiotensin II-mediated signal transduction

scientific article published on November 1, 1992

Dose-dependent effects of gonadotropin releasing hormone on matrix metalloproteinase (MMP)-2, and MMP-9 and tissue specific inhibitor of metalloproteinases-1 messenger ribonucleic acid levels in human decidual Stromal cells in vitro

scientific article published on 01 February 2003

Dysregulated BMP2 in the Placenta May Contribute to Early-Onset Preeclampsia by Regulating Human Trophoblast Expression of Extracellular Matrix and Adhesion Molecules

scientific article published on 14 December 2021

E-cadherin inhibits tumor cell growth by suppressing PI3K/Akt signaling via β-catenin-Egr1-mediated PTEN expression.

scientific article published on 7 February 2011

EGF-Induced Connexin43 Negatively Regulates Cell Proliferation in Human Ovarian Cancer.

scientific article published on 29 May 2015

EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells?

scientific article

EGF-like growth factors induce COX-2-derived PGE2 production through ERK1/2 in human granulosa cells.

scientific article published on 3 October 2013

Effect of an aromatase inhibitor (4-acetoxy-4-androstene-3,17-dione) on the stimulatory action of luteinizing hormone on estradiol-17 beta synthesis by rat preovulatory follicles in vitro.

scientific article published on September 1981

Effect of prostaglandin F2 alpha on cytosolic free calcium ion concentrations in rat luteal cells

scientific article published on 01 August 1991

Effects of adenosine 3',5'-cyclic monophosphate, forskolin, and cholera toxin on hormone production in human term placental cells

scientific article published on 01 February 1987

Effects of alterations in maternal thyroid metabolism on embryonic thyroid development in the chick

scientific article published on June 1, 1976

Effects of cyclic adenosine monophosphate on human chorionic gonadotropin and estradiol output by cultured human placental cells.

scientific article

Effects of endogenous growth differentiation factor 9 on activin A-induced inhibin B production in human granulosa-lutein cells.

scientific article published on 21 October 2009

Effects of growth differentiation factor 8 on steroidogenesis in human granulosa-lutein cells

scientific article published on 19 November 2015

Effects of intraventricular norepinephrine on preoptic-anterior hypothalamic electrical activity in the freely-moving rat: modulation by ovarian steroid hormones.

scientific article published in December 1981

Effects of prostaglandins and luteinizing hormone-releasing hormone on phosphatidic acid-phosphatidylinositol labeling in rat granulosa cells

scientific article published on 01 April 1985

Effects of recombinant activins on steroidogenesis in human granulosa-lutein cells.

scientific article published on 25 July 2014

Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells.

scientific article

Electrical stimulation of mesencephalic noradrenergic pathway: effects on luteinizing hormone levels in blood of ovariectomized and ovariectomized, steroid-primed rats

scientific article published on 01 September 1981

Electrical stimulation of ventral versus dorsal mesencephalic tegmental areas in the conscious rat: effects on luteinizing hormone release.

scientific article published in August 1987

Endocrine signaling in ovarian surface epithelium and cancer.

scientific article published on 27 October 2006

EpCAM is up-regulated by EGF via ERK1/2 signaling and suppresses human epithelial ovarian cancer cell migration.

scientific article

Estradiol regulates gonadotropin-releasing hormone (GnRH) and its receptor gene expression and antagonizes the growth inhibitory effects of GnRH in human ovarian surface epithelial and ovarian cancer cells.

scientific article

Estrogen Inhibits Porcine Thecal Androgen Production in vitro ⬇️

scientific article published on January 1, 1979

Estrogen Treatment of Immature Rats Inhibits Ovarian Androgen Production in Vitro* ⬇️

scientific article published on May 1, 1979

Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth.

scientific article published on 20 December 2010

Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha.

scientific article

Expression and antiproliferative effect of a second form of gonadotropin-releasing hormone in normal and neoplastic ovarian surface epithelial cells

scientific article published on 01 October 2001

Expression and function of HOXA genes in normal and neoplastic ovarian epithelial cells.

scientific article published on 25 October 2008

Expression of ADAMTS-5/implantin in human decidual stromal cells: regulatory effects of cytokines.

scientific article

Expression of calbindin-D28k and its regulation by estrogen in the human endometrium during the menstrual cycle ⬇️

scientific article published on March 2, 2011

Expression of calbindin-D9k in the early pregnant rat uterus: effects of RU 486 and correlation to estrogen receptor mRNA

scientific article published on 01 June 1994

Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells.

scientific article

Expression of the messenger RNA for gonadotropin-releasing hormone and its receptor in human cancer cell lines.

scientific article

FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors.

scientific article published on 8 December 2013

Fibroblast growth factor 2 induces E-cadherin down-regulation via PI3K/Akt/mTOR and MAPK/ERK signaling in ovarian cancer cells

scientific article

Follicle-stimulating hormone activates mitogen-activated protein kinase in preneoplastic and neoplastic ovarian surface epithelial cells

scientific article published on 01 May 2002

Follicular localization of GDF 8 and its receptors in normal and PCOS ovaries

scientific article published on 2 February 2018

Functional consequences of copy number variants in miscarriage.

scientific article

Further evidence in support of a short-loop feedback action of estrogen on ovarian androgen production

scientific article published on 01 August 1980

G546A polymorphism of growth differentiation factor-9 contributes to the poor outcome of ovarian stimulation in women with diminished ovarian reserve.

scientific article published on 7 May 2010

GDNF-Induced Downregulation of miR-145-5p Enhances Human Oocyte Maturation and Cumulus Cell Viability

scientific article published on 01 July 2018

Gain of OGP, an estrogen-regulated oviduct-specific glycoprotein, is associated with the development of endometrial hyperplasia and endometrial cancer.

scientific article

GnRH regulates trophoblast invasion via RUNX2-mediated MMP2/9 expression.

scientific article published on 11 December 2015

GnRH signaling in intrauterine tissues.

scientific article published on 10 February 2009

Gonadal steroids regulate the expression of aggrecanases in human endometrial stromal cells in vitro.

scientific article

Gonadotrophin-releasing hormone antagonist induces apoptosis in human decidual stromal cells: effect on GADD45α and MAPK signaling.

scientific article published on 16 January 2012

Gonadotropin-releasing hormone (GnRH) and cyclic AMP positively regulate inhibin subunit messenger RNA levels in human placental cells

scientific article published on 01 January 1994

Gonadotropin-releasing hormone (GnRH)-I and GnRH-II induce cell growth inhibition in human endometrial cancer cells: involvement of integrin beta3 and focal adhesion kinase.

scientific article published on 05 August 2009

Gonadotropin-releasing hormone activates mitogen-activated protein kinase in human ovarian and placental cells.

scientific article

Gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor are expressed at tubal ectopic pregnancy implantation sites.

scientific article published on 23 February 2016

Gonadotropin-releasing hormone and ovarian cancer: a functional and mechanistic overview.

scientific article

Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9.

scientific article published on November 2006

Gonadotropin-releasing hormone regulates human trophoblastic cell invasion via TWIST-induced N-cadherin expression

scientific article published on January 2015

Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2.

scientific article

Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the motility of human decidual endometrial stromal cells: possible effect on embryo implantation and pregnancy.

scientific article

Gonadotropin-releasing hormone type II induces apoptosis of human endometrial cancer cells by activating GADD45alpha.

scientific article published on 14 April 2009

Gonadotropin-releasing hormone-I or -II interacts with IGF-I/Akt but not connexin 43 in human granulosa cell apoptosis.

scientific article

Gonadotropin-releasing hormone-I-mediated activation of progesterone receptor contributes to gonadotropin alpha-subunit expression in mouse gonadotrophs.

scientific article

Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via beta-catenin signaling in ovarian cancer cells.

scientific article published on 14 January 2011

Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor-alpha contributes to fosB expression in mouse gonadotrophs.

scientific article

Gonadotropin-releasing hormones I and II induce apoptosis in human granulosa cells.

scientific article published on 13 May 2008

Gonadotropin-stimulated epidermal growth factor receptor expression in human ovarian surface epithelial cells: involvement of cyclic AMP-dependent exchange protein activated by cAMP pathway.

scientific article published on 20 November 2008

Gonadotropins activate proteolysis and increase invasion through protein kinase A and phosphatidylinositol 3-kinase pathways in human epithelial ovarian cancer cells.

scientific article published on April 2006

Growth Differentiation Factor-8 Decreases StAR Expression Through ALK5-Mediated Smad3 and ERK1/2 Signaling Pathways in Luteinized Human Granulosa Cells

scientific article published on 22 September 2015

Growth differentiation factor 8 down-regulates pentraxin 3 in human granulosa cells

scientific article

Growth differentiation factor 8 induces SKOV3 ovarian cancer cell migration and E-cadherin down-regulation.

scientific article published on 29 July 2016

Growth differentiation factor 8 suppresses cell proliferation by up-regulating CTGF expression in human granulosa cells.

scientific article published on 11 November 2015

Growth differentiation factor 9 enhances activin a-induced inhibin B production in human granulosa cells.

scientific article published on 7 May 2009

Growth differentiation factor 9 reverses activin A suppression of steroidogenic acute regulatory protein expression and progesterone production in human granulosa-lutein cells

scientific article

Growth hormone-releasing hormone antagonist induces apoptosis of human endometrial cancer cells through PKCδ-mediated activation of p53/p21.

scientific article published on 13 July 2010

HER2 mediates epidermal growth factor-induced down-regulation of E-cadherin in human ovarian cancer cells.

scientific article published on 29 March 2013

HOXA7 in epithelial ovarian cancer: interrelationships between differentiation and clinical features.

scientific article

HOXB4 Immunoreactivity in Endometrial Tissues From Women With or Without Endometriosis

scientific article

Hepatocyte growth factor promotes in vitro scattering and morphogenesis of human cervical carcinoma cells.

scientific article published on August 2000

Homeobox A7 stimulates breast cancer cell proliferation by up-regulating estrogen receptor-alpha

scientific article published on 04 October 2013

Homologous and heterologous regulation of gonadotropin-releasing hormone receptor gene expression in preovulatory rat granulosa cells

article

Human ovary and placenta express messenger RNA for multiple activin receptors.

scientific article published in January 1999

Human peripheral blood mononuclear cells express gonadotropin-releasing hormone (GnRH), GnRH receptor, and interleukin-2 receptor gamma-chain messenger ribonucleic acids that are regulated by GnRH in vitro

scientific article published on 01 February 1999

Hydrogen peroxide mediates EGF-induced down-regulation of E-cadherin expression via p38 MAPK and snail in human ovarian cancer cells.

scientific article

Hypoxia-inducible factor 1 alpha mediates epidermal growth factor-induced down-regulation of E-cadherin expression and cell invasion in human ovarian cancer cells.

scientific article

ID3 mediates the TGF-β1-induced suppression of matrix metalloproteinase-1 in human granulosa cells

scientific article published on 28 June 2019

Identification of an upstream promoter in the human gonadotropin-releasing hormone receptor gene

scientific article published on 01 April 2000

Identification of estrogen response element in the aquaporin-2 gene that mediates estrogen-induced cell migration and invasion in human endometrial carcinoma.

scientific article published on 29 June 2011

Identification of novel isoforms of activin receptor-like kinase 7 (ALK7) generated by alternative splicing and expression of ALK7 and its ligand, Nodal, in human placenta

scientific article (publication date: May 2003)

Identification of potential metabolic biomarkers of polycystic ovary syndrome in follicular fluid by SWATH mass spectrometry

scientific article published on 11 June 2019

Immunolocalization of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and type I GnRH receptor during follicular development in the human ovary.

scientific article published on 5 September 2006

Impact of Axis of GHRH and GHRH Receptor on Cell Viability and Apoptosis of the Placental Choriocarcinoma Cell Line.

scientific article published on 25 February 2016

Increased AIF-1-mediated TNF-α expression during implantation phase in IVF cycles with GnRH antagonist protocol

scientific article published on 01 July 2018

Induction of polyphosphoinositide breakdown in rat corpus luteum by prostaglandin F2 alpha

scientific article published on 01 July 1986

Influence of the prodrugs 5-fluorocytosine and CPT-11 on ovarian cancer cells using genetically engineered stem cells: tumor-tropic potential and inhibition of ovarian cancer cell growth.

scientific article published on April 2010

Inhibition by estradiol-17β of porcine thecal androgen production in vitro ⬇️

scientific article published on May 1, 1979

Inhibition of aromatase activity by 8-bromo-cyclic adenosine monophosphate in cultured first-trimester human trophoblast.

scientific article

Inhibition of follicle-stimulating hormone- and adenosine-3',5'-cyclic monophosphate-induced progesterone production by calcium and protein kinase C in the rat ovary

scientific article published on 01 February 1988

Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin ⬇️

scientific article published on October 25, 2010

Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells ⬇️

scientific article published on April 11, 2011

Inhibition of progestin accumulation by activin-A in human granulosa cells

scientific article published on July 1, 1992

Inositol lipids and LHRH action in the rat ovary

scientific article published on 01 January 1989

Integrin β1 mediates epithelial growth factor-induced invasion in human ovarian cancer cells.

scientific article

Interaction of prostaglandin F2alpha and gonadotropin-releasing hormone on progesterone and estradiol production in human granulosa-luteal cells

scientific article published on 01 December 1997

Interactions of estrogen and androgen with gonadotropins on ovarian progesterone production.

scientific article published on May 1979

Interactions of steroids and gonadotropins in the control of steroidogenesis in the ovarian follicle.

scientific article published on January 1980

Interplay of pituitary adenylate cyclase-activating polypeptide with a silencer element to regulate the upstream promoter of the human gonadotropin-releasing hormone receptor gene.

scientific article

Intracellular calcium and the signaling mechanism of luteinizing hormone-releasing hormone in rat granulosa cells

scientific article published on 01 August 1992

Intracellular signaling in the gonads

scientific article published on August 1, 1992

Intragonadal signalling mechanisms in the control of steroid hormone production

scientific article (publication date: March 1992)

Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell.

scientific article

Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma

scientific article

Kisspeptin regulation of human decidual stromal cells motility via FAK-Src intracellular tyrosine kinases

scientific article published on 01 July 2019

LHRH- and (hydroxyproline9) LHRH-stimulated hCG secretion from perifused first-trimester placental cells

scientific article published on 01 January 1993

Lapatinib Inhibits Amphiregulin-induced BeWo Choriocarcinoma Cell Proliferation by Reducing ERK1/2 and AKT Signaling Pathways

scientific article published on 01 May 2019

Leptin receptor is induced in endometriosis and leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways

scientific article published on 25 November 2012

Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway

scientific article

Lithium chloride inhibits StAR and progesterone production through GSK-3β and ERK1/2 signaling pathways in human granulosa-lutein cells.

scientific article published on 31 August 2017

Loss of Sprouty2 in human high-grade serous ovarian carcinomas promotes EGF-induced E-cadherin down-regulation and cell invasion

scientific article published on 20 December 2014

Low Thyroid Hormone in Early Pregnancy Is Associated With an Increased Risk of Gestational Diabetes Mellitus.

scientific article

Luteinizing hormone-releasing hormone (LHRH)-induced arachidonic acid release in rat granulosa cells. Role of calcium and protein kinase C

scientific article published on 01 April 1987

Luteinizing hormone-releasing hormone stimulates arachidonic acid release in rat granulosa cells

scientific article published on 01 November 1985

Mapping of the gonadotropin-releasing hormone (GnRH) receptor gene to human chromosome 4q21.2 by fluorescence in situ hybridization.

scientific article

Mechanism of action of TRH: involvement of the phosphatidylinositol (PI) response in the action of TRH in rat anterior pituitary cells.

scientific article published in December 1982

Mechanism of action of luteinizing hormone-releasing hormone in rat ovarian cells.

scientific article published on August 1989

Mechanism of gonadotropin-releasing hormone (GnRH)-I and -II-induced cell growth inhibition in ovarian cancer cells: role of the GnRH-I receptor and protein kinase C pathway

scientific article published on 01 March 2006

Mechanisms involved in ATP-evoked Ca2+ oscillations in isolated human granulosa-luteal cells.

scientific article published on May 1997

Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer.

scientific article published on 12 February 2008

Metaplastic changes in cultured human ovarian surface epithelium

scientific article published on 01 October 1998

MiR-106a increases granulosa cell viability and is down-regulated in women with diminished ovarian reserve.

scientific article

Mitogen-activated protein kinases in normal and (pre)neoplastic ovarian surface epithelium

scientific article

Molecular biology of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and their receptors in humans

scientific article

Molecular cloning of the full-length cDNA encoding the human calbindin-D9k

scientific article published on July 28, 1992

Molecular mechanism(s) of endocrine-disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors

scientific article published on 20 December 2012

Multi-factorial role of GnRH-I and GnRH-II in the human ovary

scientific article (publication date: 28 April 2003)

Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression.

scientific article published on May 2007

Neurotrophins and glial cell line-derived neurotrophic factor in the ovary: physiological and pathophysiological implications

scientific article published on 01 March 2019

Neutrophil apoptosis in preeclampsia, do steroids confound the relationship?

scientific article

Nitric oxide and cGMP induce COX-2 expression and PGE2 production in human granulosa cells through CREB signaling pathway.

scientific article

Norepinephrine inhibition of pulsatile LH release: receptor specificity.

scientific article published on February 1986

Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite

scientific article published on 29 October 2019

Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells

scientific article published on 10 January 2014

Oocyte-somatic cell interactions in the human ovary-novel role of bone morphogenetic proteins and growth differentiation factors

scientific article

Overexpression of follicle-stimulating hormone receptor activates oncogenic pathways in preneoplastic ovarian surface epithelial cells.

scientific article

Overexpression of wild-type but not C134W mutant FOXL2 enhances GnRH-induced cell apoptosis by increasing GnRH receptor expression in human granulosa cell tumors.

scientific article

Oviductal glycoprotein (OVGP1, MUC9): a differentiation-based mucin present in serum of women with ovarian cancer

scientific article published on 01 January 2010

Oviductal glycoprotein, a new differentiation-based indicator present in early ovarian epithelial neoplasia and cortical inclusion cysts.

scientific article published in May 2004

P-cadherin cooperates with insulin-like growth factor-1 receptor to promote metastatic signaling of gonadotropin-releasing hormone in ovarian cancer via p120 catenin

scientific article published on 14 February 2011

P2-purinoreceptor evoked changes in intracellular calcium oscillations in single isolated human granulosa-lutein cells

scientific article published on 01 September 1996

Palmitic acid causes insulin resistance in granulosa cells via activation of JNK

scientific article published on 01 May 2019

Perturbation of intracellular calcium ion concentration in single rat granulosa cells by angiotensin II.

scientific article published in February 1989

Phoenixin-14 concentrations are increased in association with luteinizing hormone and nesfatin-1 concentrations in women with polycystic ovary syndrome.

scientific article published on 14 June 2017

Porcine calbindin-D9k gene: expression in endometrium, myometrium, and placenta in the absence of a functional estrogen response element in intron A.

scientific article published in January 1995

Potential role of gonadotrophin-releasing hormone (GnRH)-I and GnRH-II in the ovary and ovarian cancer.

scientific article

Presence of activin signal transduction in normal ovarian cells and epithelial ovarian carcinoma.

scientific article published on April 2000

Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism

scientific article

Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation.

scientific article published on September 2004

Rapid effect of GNRH1 on follicle-stimulating hormone beta gene expression in LbetaT2 mouse pituitary cells requires the progesterone receptor.

scientific article

Recombinant BMP4 and BMP7 downregulate pentraxin 3 in human granulosa cells

scientific article published on 16 December 2014

Recombinant BMP4 and BMP7 increase activin A production by up-regulating inhibin βA subunit and furin expression in human granulosa-lutein cells.

scientific article

Regulated expression of ADAMTS-12 in human trophoblastic cells: a role for ADAMTS-12 in epithelial cell invasion?

scientific article

Regulation of A Disintegrin And Metalloproteinase with ThromboSpondin repeats-1 expression in human endometrial stromal cells by gonadal steroids involves progestins, androgens, and estrogens.

scientific article published on 3 October 2006

Regulation of prostaglandin F2alpha-receptor mRNA in human granulosa-luteal cells by human chorionic gonadotrophin and prostaglandin F2alpha

scientific article published on 01 June 1998

Role of endocrine and growth factors on the ovarian surface epithelium.

scientific article published on February 2007

Role of gonadotropin-releasing hormone as an autocrine growth factor in human ovarian surface epithelium

scientific article published on 01 January 2000

Role of mitogen-activated protein kinase in prostaglandin f(2alpha) action in human granulosa-luteal cells.

scientific article

Role of protein kinase C in luteinizing hormone-releasing hormone (LHRH)-stimulated progesterone production in rat granulosa cells.

scientific article published on August 1987

SMAD-dependent signaling mediates morphogenetic protein 6-induced stimulation of connective tissue growth factor in luteinized human granulosa cells†

scientific article published on 01 August 2019

SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells

scientific article published on 31 May 2017

SNAIL mediates TGF-β1-induced down-regulation of pentraxin 3 expression in human granulosa cells.

scientific article published on 16 February 2018

SV40 early genes induce neoplastic properties in serous borderline ovarian tumor cells.

scientific article published on 3 August 2008

Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas.

scientific article published on 23 January 2008

Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling.

scientific article published on 16 March 2016

Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling

scientific article published on April 2017

Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

scientific article

Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

scientific article published on 14 January 2016

Stepwise activation of the gonadotropic signal transduction pathway, and the ability of prostaglandin F2alpha to inhibit this activated pathway

scientific article published on 01 June 1998

Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells.

scientific article published on 24 May 2006

Stimulation by prostaglandin F2 alpha of phosphatidic acid-phosphatidylinositol turnover in rat luteal cells

scientific article published on 01 October 1983

Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone in human granulosa-luteal cells.

scientific article

Stimulation of phosphatidic acid and phosphatidylinositol labeling in luteal cells by luteinizing hormone releasing hormone

scientific article published on 01 March 1983

Stimulation of progesterone secretion by recombinant follistatin-288 in human granulosa cells.

scientific article

Stimulatory Action of Androgen Administration in Vivo on Ovarian Responsiveness to Gonadotropins* ⬇️

scientific article published on April 1, 1979

Stimulatory Action of Follicle-Stimulating Hormone and Androgens on the Responsiveness of Rat Granulosa Cells to Gonadotropins in Vitro** ⬇️

scientific article published on April 1, 1979

Suppression of luteinizing hormone secretion by atrial and brain natriuretic peptides in ovariectomized rats.

scientific article published in August 1991

Sustained endoplasmic reticulum stress as a cofactor of oxidative stress in decidual cells from patients with early pregnancy loss

scientific article published on 22 December 2010

TGF-beta induces serous borderline ovarian tumor cell invasion by activating EMT but triggers apoptosis in low-grade serous ovarian carcinoma cells.

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TGF-β1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells

scientific article published on 10 January 2020

TGF-β1 Inhibits Human Trophoblast Cell Invasion by Upregulating Connective Tissue Growth Factor Expression.

scientific article published in October 2017

TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways.

scientific article published on 8 May 2015

TGF-β1 downregulates StAR expression and decreases progesterone production through Smad3 and ERK1/2 signaling pathways in human granulosa cells

scientific article published on 20 August 2014

TGF-β1 induces COX-2 expression and PGE2 production in human granulosa cells through Smad signaling pathways.

scientific article published on 8 April 2014

TGF-β1 inhibits human trophoblast cell invasion by upregulating cyclooxygenase-2

scientific article published on 30 June 2018

TGF-β1 promotes hyaluronan synthesis by upregulating hyaluronan synthase 2 expression in human granulosa-lutein cells

scientific article published on 19 August 2019

TGF-β1 promotes vitamin D-induced prostaglandin E2 synthesis by upregulating vitamin D receptor expression in human granulosa-lutein cells

scientific article published on 21 January 2020

TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways.

scientific article published on 16 August 2016

TGF-β1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation.

scientific article published on 18 December 2017

TGF-β1 up-regulates connexin43 expression: a potential mechanism for human trophoblast cell differentiation.

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TGFβ1 induces endometrial cancer cell adhesion and migration by up-regulating integrin αvβ3 via SMAD-independent MEK-ERK1/2 signaling

scientific article published on 21 March 2017

Targeting gonadotropin-releasing hormone receptor inhibits the early step of ovarian cancer metastasis by modulating tumor-mesothelial adhesion.

scientific article published on 20 November 2012

Testosterone restores ovarian aromatase activity in rats treated with a 17,20-lyase inhibitor

scientific article published on April 1, 1979

The HMGA2-IMP2 Pathway Promotes Granulosa Cell Proliferation in Polycystic Ovary Syndrome

scientific article published on 01 April 2019

The Human Gonadotropin-Inhibitory Hormone Ortholog RFamide-Related Peptide-3 Suppresses Gonadotropin-Induced Progesterone Production in Human Granulosa Cells ⬇️

scientific article published on June 12, 2012

The PI3K/Akt/mTOR signaling pathway mediates insulin-like growth factor 1-induced E-cadherin down-regulation and cell proliferation in ovarian cancer cells.

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The baboon expresses the calbindin-D9k gene in intestine but not in uterus and placenta: implication for conservation of the gene in primates

scientific article published on 01 April 1995

The human gonadotropin-releasing hormone receptor gene: complete structure including multiple promoters, transcription initiation sites, and polyadenylation signals.

scientific article

The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors

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The thyroidal response to chronic goitrogenic stimulation and the persistence of effects of early goitrogenic stimulation

scientific article published on 01 August 1976

Theca-Derived BMP4 and BMP7 Down-Regulate Connexin43 Expression and Decrease Gap Junction Intercellular Communication Activity in Immortalized Human Granulosa Cells ⬇️

scientific article published on February 5, 2013

Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia

scientific article published on 01 January 2010

Transcriptional down-regulation of human gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: role of protein kinase C and activating protein 1.

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Transcriptional regulation of the mouse calbindin-D9k gene by the ovarian sex hormone.

scientific article published on August 2003

Transcripts of testicular gonadotropin-releasing hormone, steroidogenic enzymes, and intratesticular testosterone levels in infertile men.

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Transfer of maternally injected endocrine disruptors through breast milk during lactation induces neonatal Calbindin-D9k in the rat model.

scientific article

Transforming growth factor-α induces human ovarian cancer cell invasion by down-regulating E-cadherin in a Snail-independent manner

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Transforming growth factor-β stimulates human ovarian cancer cell migration by up-regulating connexin43 expression via Smad2/3 signaling

scientific article published on 14 July 2015

Transforming growth factor-β1 increases lysyl oxidase expression by downregulating MIR29A in human granulosa lutein cells.

scientific article

Transforming growth factor-β1 inhibits trophoblast cell invasion by inducing Snail-mediated down-regulation of vascular endothelial-cadherin protein.

scientific article published on 08 October 2013

Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cells

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Transgenerational Glucose Intolerance With Igf2/H19 Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia ⬇️

scientific article published on March 23, 2012

Twist modulates human trophoblastic cell invasion via regulation of N-cadherin.

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Twist regulates cadherin-mediated differentiation and fusion of human trophoblastic cells.

scientific article published on 12 October 2011

Type I collagen down-regulates E-cadherin expression by increasing PI3KCA in cancer cells ⬇️

scientific article published on March 4, 2011

Type II gonadotropin-releasing hormone stimulates p38 mitogen-activated protein kinase and apoptosis in ovarian cancer cells.

scientific article published on June 2004

Uterotrophic effects of testosterone and 5alpha-dihydrotestosterone in intact and ovariectomized immature female rats.

scientific article published on August 1976

Vascular Endothelial Growth Factor-A (VEGF-A) Mediates Activin A-Induced Human Trophoblast Endothelial-Like Tube Formation.

scientific article published on 20 August 2015

Vasopressin rapidly stimulates phosphatidic acid-phosphatidylinositol turnover in rat anterior pituitary cells.

scientific article published in March 1985

Whole exome sequencing in recurrent early pregnancy loss

scientific article published on 28 January 2016

Wild-type p53 attenuates cancer cell motility by inducing growth differentiation factor-15 expression.

scientific article published on 17 May 2011

beta-Adrenergic suppression of progesterone-induced luteinizing hormone surge in ovariectomized, estrogen-primed rats

scientific article published on 01 February 1982

hCG-induced Sprouty2 mediates amphiregulin-stimulated COX-2/PGE2 up-regulation in human granulosa cells: a potential mechanism for the OHSS.

scientific article published on 19 August 2016

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