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List of works by Anang A. Shelat

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.

scientific article

A critical evaluation of methods to interpret drug combinations

scientific article published on 20 March 2020

A high-content screen identifies inhibitors of nuclear export of forkhead transcription factors.

scientific article

A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML

scientific article published on 16 May 2019

A high-throughput screen reveals new small-molecule activators and inhibitors of pantothenate kinases.

scientific article published on 21 January 2015

A high-throughput screening method to identify small molecule inhibitors of thyroid hormone receptor coactivator binding

scientific article published on 27 June 2006

A road less traveled by: exploring a decade of Ellman chemistry.

scientific article

A screening-based approach to circumvent tumor microenvironment-driven intrinsic resistance to BCR-ABL+ inhibitors in Ph+ acute lymphoblastic leukemia

scientific article

A solid-phase approach to the phallotoxins: total synthesis of [Ala7]-phalloidin.

scientific article published in June 2005

ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy.

scientific article published on 21 July 2015

ABCG2 requires a single aromatic amino acid to "clamp" substrates and inhibitors into the binding pocket

scientific article published on 17 February 2020

Abstracts

article by L. Bie et al published 1 April 2013 in Neuro-Oncology

Alteration of RNA Splicing by Small-Molecule Inhibitors of the Interaction between NHP2L1 and U4

scientific article published on 06 October 2017

An automated approach to efficiently reformat a large collection of compounds.

scientific article

An integrated in vitro and in vivo high-throughput screen identifies treatment leads for ependymoma.

scientific article

Assay Optimization and Screening of RNA-Protein Interactions by AlphaScreen.

scientific article published in October 2007

Automated high-throughput system to fractionate plant natural products for drug discovery

scientific article

BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action.

scientific article

Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain

scientific article published in September 2003

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

scientific article

Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer

scientific article published on 10 July 2020

Chemical genetics of Plasmodium falciparum

scientific article (publication date: 20 May 2010)

Cheminformatics aspects of high throughput screening: from robots to models: symposium summary

scientific article

Combinatorial Screening Using Orthotopic Patient Derived Xenograft-Expanded Early Phase Cultures of Osteosarcoma Identify Novel Therapeutic Drug Combinations

article

DIPG-05. A RATIONAL COMBINATION STRATEGY TARGETING ATM KINASE IN PEDIATRIC HIGH-GRADE GLIOMA

scientific article published on 23 April 2019

Design of a selective chemical probe for class I PDZ domains

scientific article published on 17 October 2006

Development and characterization of a human orthotopic neuroblastoma xenograft

scientific article

Development of a cell-based, high-throughput screening assay for ATM kinase inhibitors.

scientific article published on 24 January 2014

Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

scientific article published on 4 January 2008

Discovery of Small Molecules that Inhibit the Disordered Protein, p27(Kip1).

scientific article published on 28 October 2015

Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening.

scientific article published on 29 December 2017

Discovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylase

scientific article

Discovery of small molecule inhibitors of the interaction of the thyroid hormone receptor with transcriptional coregulators

scientific article published on 31 October 2005

Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei

scientific article published in May 2006

Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB

scientific article published on 8 April 2008

Diversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparum

scientific article (publication date: 10 May 2016)

Erratum: BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action.

scientific article published on 17 May 2018

Establishing A Preclinical Multidisciplinary Board for Brain Tumors.

scientific article published on 4 January 2018

Evaluating and evolving a screening library in academia: the St Jude approach

scientific article

Evaluation of artemisinins for the treatment of acute myeloid leukemia.

scientific article published on 28 April 2016

Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors.

scientific article published on 4 November 2017

Global phenotypic screening for antimalarials

scientific article

High-throughput assays for promiscuous inhibitors.

scientific article published on 3 July 2005

Identification and characterization of the first small molecule inhibitor of MDMX

scientific article

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses

scientific article published on 23 August 2018

Identification of small molecule activators of BMP signaling

scientific article

Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents

scientific article published on 24 December 2018

Ligand binding mode prediction by docking: mdm2/mdmx inhibitors as a case study

scientific article published on 21 January 2014

MAIP: A Prediction Platform for Predicting Blood-Stage Malaria Inhibitors

scientific article

MAIP: A web service for predicting blood-stage malaria inhibitors

scientific article

MEDULLOBLASTOMA

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

scientific article published on 14 February 2020

Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group.

scientific article published on 22 November 2013

Metabolic Activation of CaMKII by Coenzyme A

scholarly article by Francis McCoy published in November 2013

Metabolic activation of CaMKII by coenzyme A.

scientific article published on 03 October 2013

Modeling and targeting of erythroleukemia by hematopoietic genome editing

scientific article

Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating.

scientific article published on 27 June 2003

Novel vitexin-inspired scaffold against leukemia

scientific article published on 30 January 2018

Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1

scientific article

Optimization of a non-radioactive high-throughput assay for decarboxylase enzymes.

scientific article

Orthotopic patient-derived xenografts of paediatric solid tumours

scientific article published on 30 August 2017

PCM-22A NEW APPROACH OF PRECLINICAL TESTING OF CHEMOTHERAPIES - AN EXAMPLE OF BRAIN TUMOUR THERAPY.

scientific article

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

scientific article published on 02 July 2021

Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma

scientific article

Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors

scientific article

Robust Classification of Small-Molecule Mechanism of Action Using a Minimalist High-Content Microscopy Screen and Multidimensional Phenotypic Trajectory Analysis

scientific article

SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents

scientific article published on 19 August 2021

Scaffold composition and biological relevance of screening libraries.

scientific article

Searching for new antimalarial therapeutics amongst known drugs

scientific article

Shared Consensus Machine Learning Models for Predicting Blood Stage Malaria Inhibition

scientific article

Structure-guided development of selective TbcatB inhibitors

scientific article published on October 2009

Synthesis and evaluation of colletoic acid core derivatives.

scientific article published on 20 January 2016

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma

scientific article published on 10 April 2015

Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox

scientific article published on 6 July 2017

Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention

scientific article published on May 2017

Targeting oxidative stress in embryonal rhabdomyosarcoma.

scientific article published on December 2013

Targeting the DNA repair pathway in Ewing sarcoma

scientific article published on 23 October 2014

The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities

scientific article published on 9 June 2015

The interdependence between screening methods and screening libraries.

scientific article

The role of ZA channel water-mediated interactions in the design of bromodomain-selective BET inhibitors

scientific article published on 22 March 2018

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease

scientific article

UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries

scientific article

Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway

scientific article

Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway

scientific article published on 28 June 2019

Virtual-screening workflow tutorials and prospective results from the Teach-Discover-Treat competition 2014 against malaria

scientific article published on 17 July 2017

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