List of works - Benjamin J Hackel

A Gradient of Sitewise Diversity Promotes Evolutionary Fitness for Binder Discovery in a Three-Helix Bundle Protein Scaffold.

scientific article

Affibody-Indocyanine Green Based Contrast Agent for Photoacoustic and Fluorescence Molecular Imaging of B7-H3 Expression in Breast Cancer

scientific article published on 24 May 2019

Biophysical Characterization Platform Informs Protein Scaffold Evolvability

scientific article published on 18 February 2019

Cellular-Based Selections Aid Yeast-Display Discovery of Genuine Cell-Binding Ligands: Targeting Oncology Vascular Biomarker CD276

scientific article published on 24 January 2019

Chemical End Group Modified Diblock Copolymers Elucidate Anchor and Chain Mechanism of Membrane Stabilization

scientific article published on 24 May 2017

Computationally Aided Discovery of LysEFm5 Variants with Improved Catalytic Activity and Stability

scientific article published on 03 February 2020

Constrained Combinatorial Libraries of Gp2 Proteins Enhance Discovery of PD-L1 Binders

scientific article published on 05 June 2018

Engineered Charge Redistribution of Gp2 Proteins through Guided Diversity for Improved PET Imaging of Epidermal Growth Factor Receptor

scientific article published on 05 April 2018

Engineering Reversible Cell-Cell Interactions with Lipid Anchored Prosthetic Receptors

scientific article published on 23 March 2018

Engineering an EGFR-binding Gp2 domain for increased hydrophilicity

scientific article published on 30 December 2018

Evaluation of affibody charge modification identified by synthetic consensus design in molecular PET imaging of epidermal growth factor receptor

scientific article published on 09 November 2017

Fine Epitope Mapping of the CD19 Extracellular Domain Promotes Design

scientific article published on 21 November 2019

Identification and elucidation of proline-rich antimicrobial peptides with enhanced potency and delivery

scientific article published on 21 July 2019

Influence of Cholesterol and Bilayer Curvature on the Interaction of PPO-PEO Block Copolymers with Liposomes

scientific article published on 22 May 2019

Influence of the Headgroup on the Interaction of Poly(ethylene oxide)-Poly(propylene oxide) Block Copolymers with Lipid Bilayers

scientific article published on 16 March 2020

Mining and statistical modeling of natural and variant class IIa bacteriocins elucidates activity and selectivity profiles across species

scientific article published on 11 September 2020

Multispecies activity screening of microcin J25 mutants yields antimicrobials with increased specificity toward pathogenic Salmonella species relative to human commensal Escherichia coli

scientific article published on 20 July 2018

Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density

scientific article published on 17 December 2018

PEO-PPO Diblock Copolymers Protect Myoblasts from Hypo-Osmotic Stress In Vitro Dependent on Copolymer Size, Composition, and Architecture.

scientific article published on 23 May 2017

PyMOL360: Multi-user gamepad control of molecular visualization software.

scientific article published on 20 September 2016

Quantifying Binding of Ethylene Oxide-Propylene Oxide Block Copolymers with Lipid Bilayers

scientific article published on 25 October 2017

Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins

scientific article published on 15 July 2019

Spatial Distribution of PEO-PPO-PEO Block Copolymer and PEO Homopolymer in Lipid Bilayers

scientific article published on 27 March 2020

Surface Plasmon Resonance Study of the Binding of PEO-PPO-PEO Triblock Copolymer and PEO Homopolymer to Supported Lipid Bilayers

scientific article published on 01 June 2018

Systematic Mutagenesis of Oncocin Reveals Enhanced Activity and Insights into the Mechanisms of Antimicrobial Activity

scientific article published on 08 October 2018

Titratable Avidity Reduction Enhances Affinity Discrimination in Mammalian Cellular Selections of Yeast-Displayed Ligands