List of works - David G Russell

2-N-Arylthiazole inhibitors of Mycobacterium tuberculosis

scientific article published on 27 July 2017

A novel, sensitive dual-indicator cell line for detection and quantification of inducible, replication-competent latent HIV-1 from reservoir cells

scientific article published on 18 December 2019

Adherent and invasive Escherichia coli is associated with granulomatous colitis in boxer dogs

scientific article

Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults

scientific article published on 29 November 2017

Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis

scientific article

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

scientific article

Cell wall lipids from Mycobacterium bovis BCG are inflammatory when inoculated within a gel matrix: characterization of a new model of the granulomatous response to mycobacterial components

scientific article published in May 2005

Cellular Microbiology: The metabolic interface between host cell and pathogen

scientific article published on 07 July 2019

Correction: Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection.

scientific article published on 14 July 2017

Decreased outer membrane permeability protects mycobacteria from killing by ubiquitin-derived peptides

scientific article published on 06 August 2009

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations

scientific article published on 17 May 2013

Detection and quantification of microbial manipulation of phagosomal function

scientific article

Development of a novel, cell-based chemical screen to identify inhibitors of intraphagosomal lipolysis in macrophages.

scientific article

Dynamic quantitative assays of phagosomal function

scientific article published on October 2013

Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis ⬇️

scientific journal article

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models

scientific article published on 15 August 2018

Equine bronchial epithelial cells differentiate into ciliated and mucus producing cells in vitro

scientific article published on 14 November 2009

Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection

scientific article published in September 2014

Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo

scientific article published on 12 December 2018

Expression of the filarial nematode phosphorylcholine-containing glycoprotein, ES62, is stage specific.

scientific article published in August 2002

Fibrinogen regulates the cytotoxicity of mycobacterial trehalose dimycolate but is not required for cell recruitment, cytokine response, or control of mycobacterial infection ⬇️

scientific article

Foamy macrophages and the progression of the human tuberculosis granuloma

scientific article

Functional Analysis of Phagocyte Activity in Whole Blood from HIV/Tuberculosis-Infected Individuals Using a Novel Flow Cytometry-Based Assay

scientific article published on 28 September 2017

Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival

scientific article

Genetic toggling of alkaline phosphatase folding reveals signal peptides for all major modes of transport across the inner membrane of bacteria

scientific article

Growing and Handling of Mycobacterium tuberculosis for Macrophage Infection Assays.

scientific article published on January 2017

Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny.

scientific article published on 2 March 2018

Host transcriptional responses following ex vivo re-challenge with Mycobacterium tuberculosis vary with disease status

scientific article published on 4 October 2017

Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages

scientific article published in May 2015

Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo.

scientific article published on 25 April 2016

Immunometabolism at the interface between macrophages and pathogens

scientific article published on 01 May 2019

Induction of ER stress in macrophages of tuberculosis granulomas

scientific article

Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts

scientific article

Infection of macrophages with Mycobacterium tuberculosis induces global modifications to phagosomal function

scientific article

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1-infected human macrophages

article

Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress

scientific article published on 10 January 2013

Intraphagosomal measurement of the magnitude and duration of the oxidative burst.

scientific article published on April 2009

Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study

scientific article published on 2 July 2015

Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection

scientific article

Lysosomal ubiquitin and the demise of Mycobacterium tuberculosis

scientific article published on 21 August 2007

M. tuberculosis Rv2252 encodes a diacylglycerol kinase involved in the biosynthesis of phosphatidylinositol mannosides (PIMs)

scientific journal article

MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage

scientific article published on 17 November 2016

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis

scientific article

Macrophage Activation Downregulates the Degradative Capacity of the Phagosome

scientific article published on 01 March 2007

Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis.

scientific article published on 26 April 2018

Mycobacterial trehalose dimycolate reprograms macrophage global gene expression and activates matrix metalloproteinases

scientific article

Mycobacterium and the coat of many lipids

scientific article

Mycobacterium tuberculosis Invasion of Macrophages: Linking Bacterial Gene Expression to Environmental Cues

article

Mycobacterium tuberculosis and the intimate discourse of a chronic infection

scientific article

Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection

scientific article

Mycobacterium tuberculosis responds to chloride and pH as synergistic cues to the immune status of its host cell

scientific article (publication date: 2013)

Mycobacterium tuberculosis wears what it eats

scientific article

Mycobacterium tuberculosis: Readouts of Bacterial Fitness and the Environment Within the Phagosome

scientific article published on January 2017

New ways to arrest phagosome maturation

scientific article published on 01 April 2007

Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment

scientific article (publication date: February 2015)

Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis

scientific article

Nutrition and the Gut Microbiota in 10- to 18-Month-Old Children Living in Urban Slums of Mumbai, India

scientific article published on 23 September 2020

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway

scientific article

Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism

scientific journal article

Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria

scientific article

Perspective: Graduation time

scientific article published in Nature

Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4.

scientific article

Phagosomes, fatty acids and tuberculosis

scientific article

Protective immunity against tuberculosis: what does it look like and how do we find it?

scientific article published on 18 August 2017

Quantification of Mycobacterium avium subsp. paratuberculosis (MAP) survival in monocyte-derived macrophages

scientific article published on 14 August 2010

Rv3723/LucA coordinates fatty acid and cholesterol uptake in Mycobacterium tuberculosis

scientific article

Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung

scientific article published on 22 July 2021

Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function

scientific article

Staphylococcus and the Healing Power of Pus

scientific article published on 01 March 2008

Structural characterization of cardiolipin by tandem quadrupole and multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization

scientific article published in April 2005

Structural characterization of phosphatidyl-myo-inositol mannosides from Mycobacterium bovis Bacillus Calmette Guérin by multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization. I. PIMs and lyso-PIMs

scientific article published on 30 November 2006

Structural characterization of phosphatidyl-myo-inositol mannosides from Mycobacterium bovis Bacillus Calmette Gúerin by multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization. II. Monoacyl- and diacyl-PIMs

scientific article published on 30 November 2006

TLR signalling and phagosome maturation: an alternative viewpoint

scientific article published on 08 March 2007

TZM-gfp cells: a tractable fluorescent tool for analysis of rare and early HIV-1 infection

scientific article published on 16 November 2020

The Galvanizing of Mycobacterium tuberculosis: An Antimicrobial Mechanism ⬇️

scientific article published on September 15, 2011

The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking

scientific article

The Minimal Unit of Infection: Mycobacterium tuberculosis in the Macrophage

scientific article published on December 2016

The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence

scientific journal article

The evolutionary pressures that have molded Mycobacterium tuberculosis into an infectious adjuvant

scientific article published on 3 January 2013

The genetic requirements of fatty acid import by within macrophages

scientific article published on 08 February 2019

The ins and outs of the Mycobacterium tuberculosis-containing vacuole

scientific article published on 31 May 2016

The kinetics of phagosome maturation as a function of phagosome/lysosome fusion and acquisition of hydrolytic activity

scientific article published in May 2005

The macrophage marches on its phagosome: dynamic assays of phagosome function.

scientific article published on 10 July 2009

Toll-like receptors and phagosome maturation

scientific article published on 01 March 2007

Trans-species communication in the Mycobacterium tuberculosis-infected macrophage

scientific article

Transcriptional responses of Mycobacterium tuberculosis to lung surfactant

scientific article published on 14 January 2009

Trp'ing tuberculosis

scientific article

Tuberculosis Progression Does Not Necessarily Equate with a Failure of Immune Control

scientific article published on 27 June 2019

Tuberculosis: what we don't know can, and does, hurt us.

scientific article

Who puts the tubercle in tuberculosis?

scientific article published on 11 December 2006

aprABC: a Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome

scientific article published on 14 March 2011

List of works by David G Russell

2-N-Arylthiazole inhibitors of Mycobacterium tuberculosis

A novel, sensitive dual-indicator cell line for detection and quantification of inducible, replication-competent latent HIV-1 from reservoir cells

Adherent and invasive Escherichia coli is associated with granulomatous colitis in boxer dogs

Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults

Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

Cell wall lipids from Mycobacterium bovis BCG are inflammatory when inoculated within a gel matrix: characterization of a new model of the granulomatous response to mycobacterial components

Cellular Microbiology: The metabolic interface between host cell and pathogen

Correction: Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection.

Decreased outer membrane permeability protects mycobacteria from killing by ubiquitin-derived peptides

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations

Detection and quantification of microbial manipulation of phagosomal function

Development of a novel, cell-based chemical screen to identify inhibitors of intraphagosomal lipolysis in macrophages.

Dynamic quantitative assays of phagosomal function

Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis ⬇️

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models

Equine bronchial epithelial cells differentiate into ciliated and mucus producing cells in vitro

Exploitation of Mycobacterium tuberculosis reporter strains to probe the impact of vaccination at sites of infection

Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo

Expression of the filarial nematode phosphorylcholine-containing glycoprotein, ES62, is stage specific.

Fibrinogen regulates the cytotoxicity of mycobacterial trehalose dimycolate but is not required for cell recruitment, cytokine response, or control of mycobacterial infection ⬇️

Foamy macrophages and the progression of the human tuberculosis granuloma

Functional Analysis of Phagocyte Activity in Whole Blood from HIV/Tuberculosis-Infected Individuals Using a Novel Flow Cytometry-Based Assay

Functional genetic diversity among Mycobacterium tuberculosis complex clinical isolates: delineation of conserved core and lineage-specific transcriptomes during intracellular survival

Genetic toggling of alkaline phosphatase folding reveals signal peptides for all major modes of transport across the inner membrane of bacteria

Growing and Handling of Mycobacterium tuberculosis for Macrophage Infection Assays.

Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogeny.

Host transcriptional responses following ex vivo re-challenge with Mycobacterium tuberculosis vary with disease status

Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages

Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo.

Immunometabolism at the interface between macrophages and pathogens

Induction of ER stress in macrophages of tuberculosis granulomas

Infection by tubercular mycobacteria is spread by nonlytic ejection from their amoeba hosts

Infection of macrophages with Mycobacterium tuberculosis induces global modifications to phagosomal function

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1-infected human macrophages

Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress

Intraphagosomal measurement of the magnitude and duration of the oxidative burst.

Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study

Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection

Lysosomal ubiquitin and the demise of Mycobacterium tuberculosis

M. tuberculosis Rv2252 encodes a diacylglycerol kinase involved in the biosynthesis of phosphatidylinositol mannosides (PIMs)

MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage

MARCO, TLR2, and CD14 are required for macrophage cytokine responses to mycobacterial trehalose dimycolate and Mycobacterium tuberculosis

Macrophage Activation Downregulates the Degradative Capacity of the Phagosome

Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis.

Mycobacterial trehalose dimycolate reprograms macrophage global gene expression and activates matrix metalloproteinases

Mycobacterium and the coat of many lipids

Mycobacterium tuberculosis Invasion of Macrophages: Linking Bacterial Gene Expression to Environmental Cues

Mycobacterium tuberculosis and the intimate discourse of a chronic infection

Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection

Mycobacterium tuberculosis responds to chloride and pH as synergistic cues to the immune status of its host cell

Mycobacterium tuberculosis wears what it eats

Mycobacterium tuberculosis: Readouts of Bacterial Fitness and the Environment Within the Phagosome

New ways to arrest phagosome maturation

Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment

Novel protein acetyltransferase, Rv2170, modulates carbon and energy metabolism in Mycobacterium tuberculosis

Nutrition and the Gut Microbiota in 10- to 18-Month-Old Children Living in Urban Slums of Mumbai, India

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway

Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism

Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria

Perspective: Graduation time

Phagosome maturation proceeds independently of stimulation of toll-like receptors 2 and 4.

Phagosomes, fatty acids and tuberculosis

Protective immunity against tuberculosis: what does it look like and how do we find it?

Quantification of Mycobacterium avium subsp. paratuberculosis (MAP) survival in monocyte-derived macrophages

Rv3723/LucA coordinates fatty acid and cholesterol uptake in Mycobacterium tuberculosis

Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung

Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function

Staphylococcus and the Healing Power of Pus

Structural characterization of cardiolipin by tandem quadrupole and multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization

Structural characterization of phosphatidyl-myo-inositol mannosides from Mycobacterium bovis Bacillus Calmette Guérin by multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization. I. PIMs and lyso-PIMs

Structural characterization of phosphatidyl-myo-inositol mannosides from Mycobacterium bovis Bacillus Calmette Gúerin by multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization. II. Monoacyl- and diacyl-PIMs

TLR signalling and phagosome maturation: an alternative viewpoint

TZM-gfp cells: a tractable fluorescent tool for analysis of rare and early HIV-1 infection

The Galvanizing of Mycobacterium tuberculosis: An Antimicrobial Mechanism ⬇️

The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking

The Minimal Unit of Infection: Mycobacterium tuberculosis in the Macrophage

The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence

The evolutionary pressures that have molded Mycobacterium tuberculosis into an infectious adjuvant