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List of works by Paula Bickford

A high-fat/high-cholesterol diet inhibits growth of fetal hippocampal transplants via increased inflammation.

scientific article published on 7 March 2011

A single administration of human umbilical cord blood T cells produces long-lasting effects in the aging hippocampus

scientific article

A spirulina-enhanced diet provides neuroprotection in an α-synuclein model of Parkinson's disease.

scientific article

Acquisition of a runway motor learning task is impaired by a beta adrenergic antagonist in F344 rats.

scientific article published in August 1996

Acute peroxide treatment of rat hippocampal slices induces adenosine-mediated inhibition of excitatory transmission in area CA1

scientific article published on 01 October 1999

Age-related changes in cerebellar noradrenergic function.

scientific article published in January 1988

Age-related neurodegeneration and oxidative stress: putative nutritional intervention.

scientific article published on August 1998

Age-related reduction in responses of rat hippocampal neurons to locally applied monoamines ⬇️

scientific article published on March 1, 1988

Aging and motor learning: a possible role for norepinephrine in cerebellar plasticity.

scientific article published in January 1995

Aging leads to altered microglial function that reduces brain resiliency increasing vulnerability to neurodegenerative diseases

scientific article published on 2 February 2017

Alpha-MSH and MCH are functional antagonists in a CNS auditory gating paradigm.

scientific article

Amelioration of age-related deficits in the stimulation of synapsin phosphorylation

scientific article published on 01 March 1997

Anti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat model of Parkinson's disease

scientific article

Antioxidant protection of cerebellar β-adrenergic receptor function in aged F344 rats ⬇️

scientific article published on July 10, 1998

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

scientific article published on 25 September 2008

Astaxanthin supplementation modulates cognitive function and synaptic plasticity in young and aged mice

scientific article published on 09 February 2019

Auditory sensory gating in hippocampal neurons: a model system in the rat.

scientific article published in January 1990

Auditory sensory gating in the rat hippocampus: modulation by brainstem activity.

scientific article

Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer's disease.

scientific article

Beneficial effects of intraventricularly administered BMP-7 following a striatal 6-hydroxydopamine lesion.

scientific article

Benzodiazepine modulation of GABAergic responses is intact in the cerebellum of aged F344 rats.

scientific article published in September 2000

Beta-adrenergic modulation of GABAergic inhibition in the deep cerebellar nuclei of F344 rats

scientific article published on 01 January 1997

Blockade of caspase-1 increases neurogenesis in the aged hippocampus.

scientific article published in November 2007

Blueberry extract enhances survival of intraocular hippocampal transplants.

scientific article

Blueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinase

scientific article published on October 2008

Blueberry- and spirulina-enriched diets enhance striatal dopamine recovery and induce a rapid, transient microglia activation after injury of the rat nigrostriatal dopamine system.

scientific article published on 19 September 2005

Blueberry-enriched diet ameliorates age-related declines in NMDA receptor-dependent LTP

scientific article published on 10 August 2008

Brain-derived neurotrophic factor is required for the establishment of the proper number of dopaminergic neurons in the substantia nigra pars compacta.

scientific article published in June 2005

CD45 Deficiency Drives Amyloid-β Peptide Oligomers and Neuronal Loss in Alzheimer's Disease Mice ⬇️

scientific article published on January 26, 2011

CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation

scientific article

CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease.

scientific article

Caloric restriction enhances evoked DA overflow in striatum and nucleus accumbens of aged Fischer 344 rats.

scientific article published in July 1997

Caloric restriction prevents age-related deficits in LTP and in NMDA receptor expression.

scientific article published in May 2000

Cerebellar noradrenergic systems in aging: studies in situ and in in oculo grafts

scientific article published on 01 September 1988

Cholinergic gating of response to auditory stimuli in rat hippocampus

scientific article published on July 31, 1992

Decline in striatal dopamine D1 and D2 receptor activation in aged F344 rats.

scientific article

Desipramine and noradrenergic neurotransmission in aging: failure to respond in aged laboratory animals

scientific article published on 01 June 1987

Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease.

scientific article

Dietary blueberry supplementation affects growth but not vascularization of neural transplants.

scientific article published on 20 February 2008

Dietary supplementation exerts neuroprotective effects in ischemic stroke model.

scientific article published in February 2008

Dietary supplementations as neuroprotective therapies: focus on NT-020 diet benefits in a rat model of stroke

scientific article

Do hematopoietic cells exposed to a neurogenic environment mimic properties of endogenous neural precursors?

scientific article

Early inhibition of TNFalpha increases 6-hydroxydopamine-induced striatal degeneration.

scientific article published on 7 February 2007

Effect of normobaric hyperoxia on two indexes of synaptic function in Fisher 344 rats.

scientific article published in April 1999

Effects of NGF and BDNF on baseline glutamate and dopamine release in the hippocampal formation of the adult rat.

scientific article published on 12 January 2007

Effects of dietary restriction on motor learning and cerebellar noradrenergic dysfunction in aged F344 rats ⬇️

scientific article published on July 3, 1995

Effects of locally applied D1 and D2 agonists on striatal neurons with 6-OHDA and pertussis toxin lesions.

scientific article

Effects of the selective noradrenergic neurotoxin DSP4 on cerebellar Purkinje neuron electrophysiology

scientific article published on 01 February 1984

Electrophysiological and biochemical sequelae of the destruction of hippocampal noradrenergic afferents by DSP4.

scientific article

Electrophysiological effects of locally applied noradrenergic agents at cerebellar Purkinje neurons: receptor specificity

scientific article published on 01 October 1988

Electrophysiological effects of phencyclidine and the sigma agonist ditolylguanidine in the cerebellum of the rat

scientific article published on January 1, 1992

Electrophysiological effects of phencyclidine on rat hippocampal pyramidal neurons

scientific article published on 01 August 1981

Elementary neuronal dysfunctions in schizophrenia ⬇️

scientific article published on March 1, 1991

Erratum to: NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats.

scientific article published on 5 September 2016

Ethanol inhibits the uptake of exogenous norepinephrine from the extracellular space of the rat cerebellum

scientific article published on 01 December 1993

Exogenous NGF restores endogenous NGF distribution in the brain of the cognitively impaired aged rat.

scientific article published in March 2003

Fractalkine over expression suppresses α-synuclein-mediated neurodegeneration

scientific article published on 8 September 2014

Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy.

scientific article published on 16 January 2013

Free radical-dependent changes in constitutive Nuclear factor kappa B in the aged hippocampus.

scientific article published in October 2002

Free radical-dependent nuclear localization of Bcl-2 in the central nervous system of aged rats is not associated with Bcl-2-mediated protection from apoptosis.

scientific article published in November 2003

Frontiers in Neural Transplantation and Repair: A Special Issue Based on the 11th ASNTR Meeting.

scientific article published in April 2005

GABAB antagonists diminish the inhibitory gating of auditory response in the rat hippocampus.

scientific article published on May 1995

Glial cell line-derived neurotrophic factor reverses motor impairment in 16-17 month old rats.

scientific article published on June 1996

Grafted dopamine neurons: Morphology, neurochemistry, and electrophysiology.

scientific article published on 21 October 2009

Green fluorescent protein bone marrow cells express hematopoietic and neural antigens in culture and migrate within the neonatal rat brain.

scientific article published on April 2004

Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

scientific article published on 30 July 2020

Human and Rat Monoaminergic Neuroblasts Grafted to Rats with Unilateral Dopamine Depletions.

scientific article published in October 1992

Human umbilical cord blood treatment in a mouse model of ALS: optimization of cell dose

scientific article

Immunomodulators as Therapeutic Agents in Mitigating the Progression of Parkinson's Disease

scientific article

Impaired acquisition of novel locomotor tasks in aged and norepinephrine-depleted F344 rats

scientific article published on July 1, 1992

Improvement of memory for context by inhibition of caspase-1 in aged rats

scientific journal article

In vivo electrochemical measurements and electrophysiological studies of rat striatum following neonatal 6-hydroxydopamine treatment.

scientific article published in February 1993

Increased responsiveness of hippocampal pyramidal neurons to nicotine in aged, learning-impaired rats.

scientific article

Inhibition of Purkinje cell firing by systemic administration of phenylisopropyl adenosine: effect of central noradrenaline depletion by DSP4.

scientific article published in July 1985

Inosine reduces ischemic brain injury in rats.

scientific article published on 3 February 2005

Insulin promotes neuronal survival via the alternatively spliced protein kinase CδII isoform.

scientific article published on 24 January 2012

Interactions between phencyclidine and cholinergic excitation of hippocampal pyramidal neurons.

scientific article published in August 1982

Intracerebroventricular glial cell line-derived neurotrophic factor improves motor function and supports nigrostriatal dopamine neurons in bilaterally 6-hydroxydopamine lesioned rats

scientific article published on May 1997

Intracranial cerebellar grafts: intermediate filament immunohistochemistry and electrophysiology

scientific article published on 01 January 1984

Intravenous transplants of human adipose-derived stem cell protect the brain from traumatic brain injury-induced neurodegeneration and motor and cognitive impairments: cell graft biodistribution and soluble factors in young and aged rats

scientific article published on January 2014

Long noncoding RNA MALAT1 in exosomes drives regenerative function and modulates inflammation-linked networks following traumatic brain injury

scientific article published on 12 July 2018

Long-Term Treatment of Male F344 Rats with Deprenyl: Assessment of Effects on Longevity, Behavior, and Brain Function ⬇️

scientific article published on May 1, 1997

Long-term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model

scientific article

MALAT1 in Human Adipose Stem Cells Modulates Survival and Alternative Splicing of PKCδII in HT22 Cells

scientific article published on 14 November 2016

Membrane and receptor modifications of oxidative stress vulnerability in aging. Nutritional considerations

scientific article published on 01 November 1998

Motor learning deficits in aged rats are correlated with loss of cerebellar noradrenergic function.

scientific article published in August 1993

Multiple single units and population responses during inhibitory gating of hippocampal auditory response in freely-moving rats.

scientific article published in April 1999

NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats

scientific article published on 17 September 2015

NT-020, a natural therapeutic approach to optimize spatial memory performance and increase neural progenitor cell proliferation and decrease inflammation in the aged rat.

scientific article

Nanolipidic particles improve the bioavailability and alpha-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease.

scientific article

Neuronal nicotinic receptor agonists improve gait and balance in olivocerebellar ataxia

scientific article published on 24 May 2013

Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration.

scientific article published on 13 February 2017

Neurotransmitter release during delay eyeblink classical conditioning: role of norepinephrine in consolidation and effect of age.

scientific article published on 21 October 2008

Nicotine's oxidative and antioxidant properties in CNS.

scientific article

Novel Molecular Insights into Classical and Alternative Activation States of Microglia as Revealed by Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Proteomics

scientific article published on 30 September 2015

Nutraceutical intervention improves older adults' cognitive functioning

scientific article

Nutraceutical intervention reverses the negative effects of blood from aged rats on stem cells.

scientific article published on 26 September 2015

Oxidative stress of neural, hematopoietic, and stem cells: protection by natural compounds.

scientific article

Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain

scientific article

Pertussis toxin lesioning of the nucleus caudate-putamen attenuates adenylate cyclase inhibition and alters neuronal electrophysiological activity.

scientific article published in August 1989

Phencyclidine and auditory sensory gating in the hippocampus of the rat

scientific article published on October 1, 1992

Proteomic anaysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response

scientific article

Rapid differentiation of NT2 cells in Sertoli-NT2 cell tissue constructs grown in the rotating wall bioreactor.

scientific article

Restoration of sensory gating of auditory evoked response by nicotine in fimbria-fornix lesioned rats

scientific article published on 01 December 1995

Rosiglitazone improves contextual fear conditioning in aged rats.

scientific article published in October 2004

Schizophrenia and nicotinic receptors.

scientific article published on November 1994

Sensory gating in a computer model of the CA3 neural network of the hippocampus.

scientific article published in December 1996

Spirulina promotes stem cell genesis and protects against LPS induced declines in neural stem cell proliferation

scientific article (publication date: 5 May 2010)

Sulindac improves memory and increases NMDA receptor subunits in aged Fischer 344 rats.

scientific article

T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson's disease

scientific article published on 15 August 2020

The effects of beta-noradrenergic receptor blockade on acquisition of eyeblink conditioning in 3-month-old F344 rats.

scientific article published in September 2002

The effects of chronic treatment with N-tert-butyl-alpha-phenylnitrone on cerebellar noradrenergic receptor function in aged F344 rats

scientific article published on 01 October 1994

The promise and perils of an Alzheimer disease vaccine: a video debate.

scientific article

The soluble isoform of CX3CL1 is necessary for neuroprotection in a mouse model of Parkinson's disease.

scientific article

Time course of degenerative alterations in nigral dopaminergic neurons following a 6-hydroxydopamine lesion

scientific article published on 01 November 2000

Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning.

scientific article

Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice

scientific article published on 14 May 2020

Umbilical cord blood-derived stem cells and brain repair.

scientific article

α-Synuclein is a pathological link and therapeutic target for Parkinson's disease and traumatic brain injury.

scientific article published on 6 August 2013

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