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List of works by Isaiah J. Fidler

22 morphometric investigation of immunostained blood vessels in brain metastasis in nude mice

scientific article published on 01 December 1999

A necropsy study of canine malignant mammary neoplasms

scientific article published on 01 September 1967

A rapid colorimetric in situ mRNA hybridization technique using hyperbiotinylated oligonucleotide probes for analysis of mdr1 in mouse colon carcinoma cells.

scientific article

A rapid colorimetric in situ messenger RNA hybridization technique for analysis of epidermal growth factor receptor in paraffin-embedded surgical specimens of human colon carcinomas

scientific article published on March 1993

Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene: possible role of nitric oxide.

scientific article published in December 1997

Accelerated growth of human colon cancer cells in nude mice undergoing liver regeneration

scientific article published on 01 January 1994

Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells

scientific article published on 01 August 2000

Activation of rat alveolar macrophages to the tumoricidal state in the presence of progressively growing pulmonary metastases

scientific article published on 01 June 1981

Activation of the platelet-derived growth factor-receptor enhances survival of murine bone endothelial cells

scientific article

Activation of tumoricidal properties in human blood monocytes by liposomes containing lipophilic muramyl tripeptide

scientific article published on 01 May 1983

Activation of tumoricidal properties in macrophages by lymphokines encapsulated in liposomes

scientific article published on 01 January 1982

Activation of tumoricidal properties in peripheral blood monocytes of patients with colorectal carcinoma

scientific article published in February 1986

Active specific immunotherapy against occult brain metastasis.

scientific article published in March 2003

Amplification of telomeric DNA directly correlates with metastatic potential of human and murine cancers of various histological origin

scientific article

An orthotopic nude mouse model of oral tongue squamous cell carcinoma.

scientific article published on January 2002

Angiogenesis and growth of murine colon carcinoma are dependent on infiltrating leukocytes.

scientific article

Angiogenesis and lung cancer: potential for therapy

scientific article published on 01 December 2000

Antiproliferative activity of liposome-encapsulated transforming growth factor-beta against MDA-MB-435 human breast carcinoma cells

scientific article published on 01 January 1989

Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors

scientific article published on July 2005

Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation

scientific article published on June 2005

Arrest and retention of multilamellar liposomes in the brain of normal mice or mice bearing experimental brain metastases

scientific article published on 01 January 1989

Augmentation of antiproliferative activity of interferon alfa against human bladder tumor cell lines by encapsulation of interferon alfa within liposomes

scientific article

Binding of liposomes to human bladder tumor epithelial cell lines: implications for an intravesical drug delivery system for the treatment of bladder cancer

scientific article published on 01 January 1989

Bioassay using epidermal keratinocytes to determine phosphorylation status of the epidermal growth factor receptor in distant neoplasms

scientific article published on January 2004

Biochemical, morphological, and ultrastructural studies on the uptake of liposomes by murine macrophages

scientific article published on 01 February 1981

Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice.

scientific article published in March 2003

Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice.

scientific article published on June 2003

Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas

scientific article published on September 2002

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma

scientific article published on 01 June 2000

Blockade of the epidermal growth factor receptor signaling inhibits angiogenesis leading to regression of human renal cell carcinoma growing orthotopically in nude mice

scientific article published in November 2002

Cell density-dependent regulation of basic fibroblast growth factor expression in human renal cell carcinoma cells

scientific article published on 01 March 1996

Cell surface properties of B16 melanoma variants with differing metastatic potential

scientific article published on 01 May 1980

Chemosensitization of cancer cells by the staurosporine derivative CGP 41251 in association with decreased P-glycoprotein phosphorylation

scientific article published on 01 January 1997

Circulating monocytes expressing CD31: implications for acute and chronic angiogenesis

scientific article published on 06 April 2009

Clonal stimulation or inhibition of human colon carcinomas and human renal carcinomas mediated by transforming growth factor-beta 1.

scientific article

Consistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouse

scientific article

Constitutive and inducible interleukin 8 expression by hypoxia and acidosis renders human pancreatic cancer cells more tumorigenic and metastatic.

scientific article

Constitutive expression of interferon beta in differentiated epithelial cells exposed to environmental stimuli

scientific article published on 01 October 1998

Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma

scientific article

Construction of a novel constitutively active chimeric EGFR to identify new targets for therapy

scientific article

Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice

scientific article published on August 2002

Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites

scientific article published on 01 September 1989

Cytostatic and cytolytic effects of human recombinant tumor necrosis factor on human renal cell carcinoma cell lines derived from a single surgical specimen.

scientific article

Delivery of macrophage-augmenting factors encapsulated in liposomes for destruction of tumor metastases

scientific article published on 01 January 1982

Design of liposomes to improve delivery of macrophage-augmenting agents to alveolar macrophages

scientific article published on 01 December 1980

Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase gene

scientific article published on 01 March 1997

Differential expression of E-cadherin and type IV collagenase genes predicts outcome in patients with stage I non-small cell lung carcinoma

scientific article published on March 2000

Differential regulation of metalloelastase activity in murine peritoneal macrophages by granulocyte-macrophage colony-stimulating factor and macrophage colony-stimulating factor

scientific article published on 01 December 1996

Differential regulation of type IV collagenases and metalloelastase in murine macrophages by the synthetic bacterial lipopeptide JBT 3002

scientific article published on 01 June 2000

Differential release of TNF-alpha, IL 1, and PGE2 by human blood monocytes subsequent to interaction with different bacterial derived agents

scientific article published on 01 January 1990

Direct antiproliferative effects of recombinant human interferon-alpha B/D hybrids on human tumor cell lines

scientific article published on 01 April 1987

Direct correlation between expression of endogenous inducible nitric oxide synthase and regression of M5076 reticulum cell sarcoma hepatic metastases in mice treated with liposomes containing lipopeptide CGP 31362

scientific article published on 01 July 1995

Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model

scientific article published in May 2005

Editor's Note: Inhibition of Platelet-derived Growth Factor-mediated Proliferation of Osteosarcoma Cells by the Novel Tyrosine Kinase Inhibitor STI571

scientific article published on 01 May 2019

Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases

scientific article published on March 2003

Effects of liposome structure and lipid composition on the activation of the tumoricidal properties of macrophages by liposomes containing muramyl dipeptide

scientific article published on 01 January 1982

Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes

scientific article published in June 1991

Enhancement of murine tumor cell sensitivity to adriamycin by presentation of the drug in phosphatidylcholine-phosphatidylserine liposomes.

scientific article published in June 1990

Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer

scientific article published in August 2003

Evidence for metastatic heterogeneity of human renal cell carcinoma

scientific article published on 01 November 1988

Evidence for the causal role of endogenous interferon-alpha/beta in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms

scientific article published on 01 January 2002

Evidence that the process of murine melanoma metastasis is sequential and selective and contains stochastic elements

scientific article

Expression level of the nm23 gene in clonal populations of metastatic murine and human neoplasms

scientific article published on October 15, 1992

Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential.

scientific article published on December 2006

Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice

scientific article published on 01 March 1998

Expression of inflammatory cytokines by murine macrophages activated with a new synthetic lipopeptide JT3002

scientific article published on 01 October 1997

Expression of interferon-beta is associated with growth arrest of murine and human epidermal cells

scientific article published on 01 May 1999

Expression of interleukin 8 correlates with the metastatic potential of human melanoma cells in nude mice

scientific article published on 01 June 1994

Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage

scientific article published on 01 June 2005

Expression of interleukin-8 in human metastatic endometrial carcinoma cells and its regulation by inflammatory cytokines

scientific article published on 01 January 2001

Expression of metastasis-related genes in human epithelial ovarian tumors

scientific article published on January 2002

Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines

scientific article published on April 2004

Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells

scientific article published on 01 October 1994

Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis.

scientific article published in September 2000

Formation of solid tumors by a single multinucleated cancer cell

scientific article

Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain

scientific article

Gene expression profile of metastatic human pancreatic cancer cells depends on the organ microenvironment

scientific article published on January 2007

Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis

scientific article

Genetic control of cancer metastasis

scientific article published on 01 February 1990

Heterogeneous response of human colon cancer cells to the cytostatic and cytotoxic effects of recombinant human cytokines: interferon-alpha, interferon-gamma, tumor necrosis factor, and interleukin-1.

scientific article

Highly metastatic human prostate cancer growing within the prostate of athymic mice overexpresses vascular endothelial growth factor

scientific article published on April 1999

Human lymphokine preparations which generate tumoricidal properties of human monocytes in vitro may be distinct from gamma interferon

scientific article published on 01 January 1985

Human recombinant interferons-beta and -gamma decrease gelatinase production and invasion by human KG-2 renal-carcinoma cells

scientific article published on 01 August 1994

Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine

scientific article published on April 2004

Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells

scientific article published on 01 November 1999

Identification and validation of SRC and phospho-SRC family proteins in circulating mononuclear cells as novel biomarkers for pancreatic cancer

scientific article

Immunotherapy of murine renal adenocarcinoma by systemic administration of liposomes containing the synthetic macrophage activator CGP 31362 or CGP 19835A in combination with interleukin 2 or gamma-interferon

scientific article published on 01 March 1992

Impact of sentinel lymphadenectomy on survival in a murine model of melanoma

article

In situ activation of mouse lung macrophages by coadministration of liposomes containing the lipopeptide CGP 31362 and interleukin 2 involves interaction with T lymphocytes and natural killer cells

scientific article published on 01 December 1991

In situ activation of mouse macrophages and therapy of spontaneous renal cell cancer metastasis by liposomes containing the lipopeptide CGP 31362

scientific article published on 01 January 1991

In vitro activation of murine Kupffer cells by lymphokines or endotoxins to lyse syngeneic tumor cells.

scientific article published in December 1984

In vivo modulation of macrophage tumoricidal activity by oral administration of the liposome-encapsulated macrophage activator CGP 19835A

scientific article published on 01 November 1994

In vivo selection of highly metastatic cells from surgical specimens of different primary human colon carcinomas implanted into nude mice.

scientific article published in April 1988

Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice

scientific article

Induction of chemokine secretion and enhancement of contact-dependent macrophage cytotoxicity by engineered expression of granulocyte-macrophage colony-stimulating factor in human colon cancer cells

scientific article published on 01 March 2000

Induction of ductal and stromal hyperplasia by basic fibroblast growth factor produced by human pancreatic carcinoma

scientific article published on 01 October 2001

Induction of nitric oxide production and tumoricidal properties in murine macrophages by a new synthetic lipopeptide JBT3002 encapsulated in liposomes

scientific article published on 01 September 1998

Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells

scientific article published on 01 December 1990

Influence of organ environment on the growth, selection, and metastasis of human colon carcinoma cells in nude mice.

scientific article published on December 1988

Influence of organ microenvironment on pigmentation of a metastatic murine melanoma

scientific article published in April 1988

Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice.

scientific article published on July 2006

Inhibition of basic fibroblast growth factor expression, angiogenesis, and growth of human bladder carcinoma in mice by systemic interferon-alpha administration

scientific article published on 01 February 1998

Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice

scientific article

Inhibition of growth and metastasis of orthotopic human prostate cancer in athymic mice by combination therapy with pegylated interferon-alpha-2b and docetaxel

scientific article published in October 2002

Inhibition of murine melanoma experimental metastasis by recombinant desulfatohirudin, a highly specific thrombin inhibitor

scientific article published on 01 September 1991

Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model.

scientific article published on December 2003

Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571.

scientific article published on November 2002

Intensified regression of colon cancer liver metastases in mice treated with irinotecan and the immunomodulator JBT 3002

scientific article published on 01 May 2000

Interferon-alpha prevents selection of doxorubicin-resistant undifferentiated-androgen-insensitive metastatic human prostate cancer cells.

scientific article published in September 2001

Interferon-beta prevents the upregulation of interleukin-8 expression in human melanoma cells

scientific article published on 01 August 1996

Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas

scientific article

Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine

scientific article

Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas

scientific article published on 01 May 1996

Intratumoral heterogeneity for and epigenetic modulation of mdr-1 expression in murine melanoma

scientific article published on 01 August 1997

Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors.

scientific article published on 17 January 2008

Intravesical liposomal muramyl tripeptide phosphatidylethanolamine treatment of human bladder carcinoma growing in nude mice

scientific article published on June 1995

Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells

scientific article published on 01 February 1994

Isolation and Characterization of Metastatic Variants from Human Transitional Cell Carcinoma Passaged by Orthotopic Implantation in Athymic Nude Mice

scientific article published on October 1, 1995

Isolation of human colon carcinoma cells for resistance to a single interferon associated with cross-resistance to multiple recombinant interferons: alpha, beta, and gamma

scientific article published on March 1990

Isolation of tumoricidal macrophages from lung melanoma metastases of mice treated systemically with liposomes containing a lipophilic derivative of muramyl dipeptide

scientific article published on 01 November 1982

Lack of comparability between binding of monoclonal antibodies to melanoma cells in vitro and localization in vivo

scientific article published on 01 May 1989

Leukocyte-induced angiogenesis and subcutaneous growth of B16 melanoma.

scientific article

Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells

scientific article published on 01 January 1995

Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-kappaB activity

scientific article published on 01 March 2000

Level of protein kinase C activity correlates directly with resistance to adriamycin in murine fibrosarcoma cells.

scientific article

Liposome encapsulation of muramyl peptides for activation of macrophage cytotoxic properties

scientific article published on 01 January 1986

Loss of adhesion in the circulation converts amelanotic metastatic melanoma cells to melanotic by inhibition of AKT

scientific article

Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice

scientific article published on 23 June 2015

Macrophage content of metastatic and nonmetastatic rodent neoplasms

scientific article published on 01 June 1981

Macrophage recognition of self from nonself: implications for the interaction of macrophages with neoplastic cells

scientific article published on 01 January 1986

Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma

scientific article published on 01 March 1997

Maintenance of intestinal epithelium structural integrity and mucosal leukocytes during chemotherapy by oral administration of muramyl tripeptide phosphatidylethanolamine

scientific article published in December 1996

Mechanisms of Cancer Invasion and Metastasis / Isaiah J. Fidler . - (1975)

article

Mechanisms of combined effects of gamma-interferon and 5-fluorouracil on human colon cancers implanted into nude mice.

scientific article

Metastatic potential of cloned murine melanoma cells transfected with activated c-Ha-ras.

scientific article

Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model

scientific article published on July 2008

Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer

scientific article

Modulation of the cancer cell transcriptome by culture media formulations and cell density

scientific article

Molecular regulation of UVB-induced cutaneous angiogenesis

scientific article published on 01 November 1998

Multiparametric in situ mRNA hybridization analysis of gastric biopsies predicts lymph node metastasis in patients with gastric carcinoma.

scientific article published in November 2002

Multiparametric in situ messenger RNA hybridization analysis to detect metastasis-related genes in surgical specimens of human colon carcinomas.

scientific article

Neoadjuvant platelet derived growth factor receptor inhibitor therapy combined with docetaxel and androgen ablation for high risk localized prostate cancer

scientific article published on 13 November 2008

Neoplastic angiogenesis--not all blood vessels are created equal

scientific article published on 01 July 2004

Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2

scientific article published on August 14, 1997

Nitric oxide-mediated tumoricidal activity of murine microglial cells

scientific article

Nonselective destruction of murine neoplastic cells by syngeneic tumoricidal macrophages.

scientific article

Nuclear factor-kappaB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice

scientific article published on 01 June 2000

Optimization of the liposomes encapsulating a new lipopeptide CGP 31362 for efficient activation of tumoricidal properties in monocytes and macrophages

scientific article published on 01 August 1991

Organ site-dependent expression of basic fibroblast growth factor in human renal cell carcinoma cells.

scientific article published in August 1994

Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells.

scientific article

Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluorouracil.

scientific article published in August 1992

Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells.

scientific article

Phase I and pharmacologic study of PKI166, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies

scientific article

Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells in human renal cell carcinoma is a primary target for therapy by tyrosine kinase inhibitors

scientific article

Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors

scientific article

Plasma membrane-associated tumor necrosis factor. A non-integral membrane protein possibly bound to its own receptor

scientific article published on 01 February 1988

Plasma protein profiling for diagnosis of pancreatic cancer reveals the presence of host response proteins

scientific article

Platelet-derived growth factor receptor inhibition and chemotherapy for castration-resistant prostate cancer with bone metastases

scientific article published in October 2007

Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer

scientific article

Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers

scientific article published on 18 September 2012

Prevention of chemotherapy- or X-irradiation-induced monocytopenia by oral administration of lipophilic muramyl tripeptide

scientific article published on 01 January 1994

Prevention of intestinal toxic effects and intensification of irinotecan's therapeutic efficacy against murine colon cancer liver metastases by oral administration of the lipopeptide JBT 3002

scientific article published on 01 September 1998

Production and utilization of human lymphokines containing macrophage-activating factor (MAF) activity

scientific article published on 01 January 1983

Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis

scientific journal article

Progressive growth of infantile cutaneous hemangiomas is directly correlated with hyperplasia and angiogenesis of adjacent epidermis and inversely correlated with expression of the endogenous angiogenesis inhibitor, IFN-beta

scientific article published on 01 March 1999

Progressive upregulation of metastasis-related genes in human colon cancer cells implanted into the cecum of nude mice

scientific article published on 01 January 1996

Prostaglandin E2 does not inhibit tumoricidal activity of mouse macrophages against adherent tumor cells

scientific article published on 01 March 1991

Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages

scientific article published on 01 September 1993

Quantitative and qualitative in vivo angiogenesis assay.

scientific article

Quantitative fluorescent microassay for identification of antiproliferative compounds

scientific article published in December 1986

Rat alveolar macrophages are susceptible to activation by free and liposome-encapsulated lymphokines

scientific article published on 01 May 1980

Reactive Astrocytes Protect Melanoma Cells from Chemotherapy by Sequestering Intracellular Calcium through Gap Junction Communication Channels

scientific article published on September 1, 2010

Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta.

scientific article published on May 2003

Regulation of disease-progression genes in human gastric carcinoma cells by interleukin 8

scientific article published on 01 July 2000

Regulation of distinct steps of angiogenesis by different angiogenic molecules

scientific article published on 01 April 1998

Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts.

scientific article published in February 1994

Regulation of interleukin-8 expression in human melanoma cells by the organ environment

scientific article published on 01 June 1995

Regulatory mechanisms for the expression of type IV collagenases/gelatinases in murine macrophages

scientific article published on 01 April 1994

Relationship of estrous irregularity, pseudopregnancy, and pregnancy to canine pyometra

scientific article published on 01 October 1966

Relative expression of E-cadherin and type IV collagenase genes predicts disease outcome in patients with resectable pancreatic carcinoma

scientific article published on January 1999

Relative expression of type IV collagenase, E-cadherin, and vascular endothelial growth factor/vascular permeability factor in prostatectomy specimens distinguishes organ-confined from pathologically advanced prostate cancers

scientific article published on June 2000

Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells.

scientific article

Search for genes that suppress cancer metastasis

scientific article published on 01 December 1996

Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar

scientific article

Selection of highly metastatic variants of different human prostatic carcinomas using orthotopic implantation in nude mice

scientific article published on September 1996

Selective delivery of drugs encapsulated in liposomes: natural targeting to macrophages involved in various disease states

scientific article published on 01 January 1983

Selective growth of human melanoma cells in the brain parenchyma of nude mice

scientific article published in October 1996

Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer.

scientific article

Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice

scientific article

Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model.

scientific article

Site-dependent differences in response of the UV-2237 murine fibrosarcoma to systemic therapy with adriamycin

scientific article published on December 1990

Site-specific expression of transferrin receptor by human colon cancer cells directly correlates with eradication by antitransferrin recombinant immunotoxin

scientific article published on 01 October 2000

Spatial and temporal expression of angiogenic molecules during tumor growth and progression

scientific article published on 01 January 1998

Specific immunotherapy against occult cancer metastases.

scientific article published in August 2002

Specific keynote: molecular determinants of angiogenesis in ovarian cancer

scientific article published on 01 January 2003

Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells

scientific article published on 01 April 2002

Stromal metalloproteinase-9 is essential to angiogenesis and progressive growth of orthotopic human pancreatic cancer in parabiont nude mice

scientific article

Superior antiproliferative effects mediated by interferon-alpha entrapped in liposomes against a newly established human lung cancer cell line

scientific article published on August 1990

Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha

Suppression of angiogenesis, tumorigenicity, and metastasis by human prostate cancer cells engineered to produce interferon-beta

scientific article published on 01 February 1999

Synergism between human recombinant gamma-interferon and muramyl dipeptide encapsulated in liposomes for activation of antitumor properties in human blood monocytes

scientific article published on 01 December 1985

Synergism between human recombinant monocyte chemotactic and activating factor and lipopolysaccharide for activation of antitumor properties in human blood monocytes

scientific article published on 01 October 1993

Synergism between lymphokines and muramyl dipeptide encapsulated in liposomes: in situ activation of macrophages and therapy of spontaneous cancer metastases

scientific article published on 01 July 1984

Synergistic activation by recombinant mouse interferon-gamma and muramyl dipeptide of tumoricidal properties in mouse macrophages

scientific article published on 01 July 1985

Synergistic therapy of human ovarian carcinoma implanted orthotopically in nude mice by optimal biological dose of pegylated interferon alpha combined with paclitaxel

scientific article published on 01 July 2002

Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse

scientific article

Targeted molecular therapy for oral cancer with epidermal growth factor receptor blockade: a preliminary report

scientific article published on 01 August 2002

Targeting platelet-derived growth factor receptor on endothelial cells of multidrug-resistant prostate cancer.

scientific article

Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis

scientific article

Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy.

scientific article

Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma.

scientific article published on December 2006

Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma

scientific article published on February 2004

Terminal differentiation and apoptosis in experimental lung metastases of human osteogenic sarcoma cells by wild type p53

scientific article published on 01 July 1994

The Brain Microenvironment and Cancer Metastasis

scientific article published on August 19, 2010

The activation of tumoricidal properties in human blood monocytes by muramyl dipeptide requires specific intracellular interaction

scientific article published on 01 March 1986

The activation of tumoricidal properties in macrophages of endotoxin responder and nonresponder mice by liposome-encapsulated immunomodulators

scientific article published on 01 March 1983

The antitumor activity of doxorubicin against drug-resistant murine carcinoma is enhanced by oral administration of a synthetic staurosporine analogue, CGP 41251.

scientific article published on January 1995

The biological behavior of canine mammary neoplasms

scientific article published on 01 November 1967

The biology of cancer metastasis and implications for therapy

scientific article published on 01 March 1987

The development of liposomes containing interferon alpha for the intravesical therapy of human superficial bladder cancer

scientific article published on June 1990

The immunogenic properties of drug-resistant murine tumor cells do not correlate with expression of the MDR phenotype

scientific article published on 01 June 1993

The relationship of estrous irregularity, pseudopregnancy, and pregnancy to the development of canine mammary neoplasms

scientific article published on 01 October 1966

The relative mRNA expression levels of matrix metalloproteinase to E-cadherin in prostate biopsy specimens distinguishes organ-confined from advanced prostate cancer at radical prostatectomy.

scientific article

The role of plasma membrane receptors and the kinetics of macrophage activation by lymphokines encapsulated in liposomes

scientific article published on 01 February 1981

The role of the organ microenvironment in the biology and therapy of cancer metastasis

scientific article published on July 2007

The seed and soil hypothesis revisited--the role of tumor-stroma interactions in metastasis to different organs

scientific article

Therapy of cancer metastasis by tumoricidal activation of tissue macrophages using liposome-encapsulated immunomodulators

scientific article published on 01 June 1998

Therapy of human pancreatic carcinoma implants by irinotecan and the oral immunomodulator JBT 3002 is associated with enhanced expression of inducible nitric oxide synthase in tumor-infiltrating macrophages

scientific article published on 01 January 2000

Therapy of multidrug resistant human prostate tumors in the prostate of nude mice by simultaneous targeting of the epidermal growth factor receptor and vascular endothelial growth factor receptor on tumor-associated endothelial cells

scientific article published on 01 December 2006

Therapy of spontaneous lung metastasis of murine renal adenocarcinoma by systemic administration of liposomes containing the macrophage activator CGP 31362

scientific article published on 01 July 1991

Tissue-specific microvascular endothelial cell lines from H-2K(b)-tsA58 mice for studies of angiogenesis and metastasis.

scientific article published on June 2003

Transcriptional induction of the melanocyte-stimulating hormone receptor in brain metastases of murine K-1735 melanoma

scientific article published on 01 January 1995

Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain

scientific article published on 13 January 2009

Transient inhibition of liver regeneration in mice by transforming growth factor-beta 1 encapsulated in liposomes

scientific article published on 01 January 1990

Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation.

scientific article

Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel

scientific article published on April 2016

Treatment of nude mice with 4-amidinoindan-1-one2???-amidinohydrazone, a new S-adenosylmethionine decarboxylase inhibitor, delays growth and inhibits metastasis of human melanoma cells

scientific article published on 01 June 1995

Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade

scientific article

Tumor cytotoxicity of rat alveolar macrophages activated in vitro by endotoxin

scientific article published on 01 March 1980

Tumor necrosis factor and IL-1 associated with plasma membranes of activated human monocytes lyse monokine-sensitive but not monokine-resistant tumor cells whereas viable activated monocytes lyse both.

scientific article published in July 1988

Type-1 transforming growth factor-beta differentially modulates tumoricidal activity of murine peritoneal macrophages against metastatic variants of the B16 murine melanoma

scientific article published on 01 September 2002

Ultrastructural studies of the interaction between liposome-activated human blood monocytes and allogeneic tumor cells in vitro

scientific article published in July 1983

Unique histological changes in lung metastases of osteosarcoma patients following therapy with liposomal muramyl tripeptide (CGP 19835A lipid)

scientific article published on 01 January 1992

Use of retroviral vectors encoding murine inducible nitric oxide synthase gene to suppress tumorigenicity and cancer metastasis of murine melanoma

scientific article published on 01 June 1997

Zonal heterogeneity for gene expression in human pancreatic carcinoma

scientific article