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List of works by Gustav Gaudernack

A K-ras 13Gly-->Asp mutation is recognized by HLA-DQ7 restricted T cells in a patient with colorectal cancer. Modifying effect of DQ7 on established cancers harbouring this mutation?

scientific article published on 01 August 1994

A TCR-based Chimeric Antigen Receptor

scientific article published on 6 September 2017

A TGF betaRII frameshift-mutation-derived CTL epitope recognised by HLA-A2-restricted CD8+ T cells

scientific article

A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines

scientific article

A human melanoma cell line, recognized by both HLA class I and class II restricted T cells, is capable of initiating both primary and secondary immune responses

scientific article published on April 1995

A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines

scientific article published in November 2003

A simple and sensitive bioassay for the detection of IL-2 activity

scientific article published on 01 November 1988

Ability of pure resting CD8+ human T cells to respond to alloantigen

scientific article published on May 1989

Accessory cell-dependent T-cell activation via Ti-CD3. Involvement of CD2-LFA-3 interactions

scientific article published in September 1988

Activation of resting, pure CD4+, and CD8+ cells via CD3. Requirements for second signals

scientific article published on 01 August 1987

Allogenic induction of thromboplastin synthesis in monocytes and endothelial cells. Biphasic effect of cyclosporin A

Analysis of infiltrating lymphocytes from fine needle aspiration biopsies in kidney transplant patients by a rapid and sensitive immunomagnetic method

scientific article published on 01 February 1989

Analysis of the autoantibody repertoire in Burkitt's lymphoma patients: frequent response against the transcription factor ATF-2.

scientific article published in December 2004

Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity

scientific article published on 11 January 2019

Antigen-presenting function of human peritoneum mesothelial cells isolated from a pancreatic carcinoma patient after mutant Ras peptide vaccination

scientific article published on 01 December 1996

Antigen-specific T cell clones restricted by DR, DRw53 (MT), or DP (SB) Class II HLA molecules. Inhibition studies with monoclonal HLA-specific antibodies

scientific article published on December 1984

Approach to analysis of single nucleotide polymorphisms by automated constant denaturant capillary electrophoresis ⬇️

scientific article published on May 15, 2003

Automated constant denaturant capillary electrophoresis applied for detection of KRAS exon 1 mutations

scientific article

Awareness and understanding of cancer immunotherapy in Europe

scientific article

Binding of ras oncogene peptides to purified HLA-DQ (alpha 1*0102, beta 1*0602) and -DR (alpha, beta 1*0101) molecules

scientific article published on 01 October 1994

Binding of ras oncogene peptides to purified HLA-DQ(alpha 1*0102,beta 1*0602) and -DR(alpha,beta 1*0101) molecules

scientific article published on June 1994

CD8+ T cells from a patient with colon carcinoma, specific for a mutant p21-Ras-derived peptide (Gly13-->Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation

scientific article published on March 1995

CD8+ T cells inhibit HIV replication in naturally infected CD4+ T cells. Evidence for a soluble inhibitor

scientific article

CDw78--a determinant on a major histocompatibility complex class II subpopulation that can be induced to associate with the cytoskeleton

scientific article

Carcinogenesis and natural selection: a new perspective to the genetics and epigenetics of colorectal cancer

scientific article

Characterisation of immune responses in pancreatic carcinoma patients after mutant p21 ras peptide vaccination

scientific article

Characterization and epitope mapping of four HLA class II reactive mouse monoclonal antibodies using transfected L cells and human cells transfected with mutants of DQB1*0302 ⬇️

scientific article published on April 1, 1995

Characterization of a monoclonal antibody recognizing a polymorphic epitope mainly on HLA-DPw2 and DPw4 molecules

scientific article published on 01 October 1989

Characterization of an HLA-DQ2-specific monoclonal antibody. Influence of amino acid substitutions in DQ beta 1*0202.

scientific article published on April 1995

Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues

scientific article

Combination of GM-CSF with antitumour vaccine strategies

scientific article

Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy

scientific article published on 01 January 2020

Cross-linking of a sequential epitope within the beta-chain of HLA-DR/DP molecules suppressing B lymphocyte growth and inducing homotypic cell aggregation

scientific article published on February 1994

Culture characterization of differentiated high endothelial venule cells from human tonsils

scientific article published on 01 March 1999

Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12Val) peptide vaccination of a patient, recognize 12Val-dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation

scientific article published on 01 September 1997

Dendritic cells engineered to express defined allo-HLA peptide complexes induce antigen-specific cytotoxic T cells efficiently killing tumour cells.

scientific article published on April 2009

Depletion of T lymphocytes from human bone marrow. Use of magnetic monosized polymer microspheres coated with T-lymphocyte-specific monoclonal antibodies.

scientific article

Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34(+) blood progenitor cells

scientific article

Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors

scientific article published in December 1997

Direct identification of all oncogenic mutants in KRAS exon 1 by cycling temperature capillary electrophoresis.

scientific article

Direct immunomagnetic quantification of lymphocyte subsets in blood

scientific article

EBV infection renders B cells resistant to growth inhibition via adenylyl cyclase

scientific article

Effect of vaccination with mutant KRAS peptides on rat colon carcinogenesis induced by azoxymethane

scientific article published on 01 January 2002

Effects of endotoxins from Bacteroides intermedius and Escherichia coli on human monocytes in vitro.

scientific article

Evaluation of dendritic cells loaded with apoptotic cancer cells or expressing tumour mRNA as potential cancer vaccines against leukemia

scientific article

Ex vivo expansion protocol for human tumor specific T cells for adoptive T cell therapy

scientific article published on 19 February 2010

Ex vivo ras peptide vaccination in patients with advanced pancreatic cancer: results of a phase I/II study

scientific article

Formation of biocompatible nanocapsules with emulsion core and pegylated shell by polyelectrolyte multilayer adsorption

scientific article published on August 2010

Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer

scientific article

Generation and characterization of gp100 peptide-specific NK-T cell clones

scientific article

Genomic instability, DNA methylation, and natural selection in colorectal carcinogenesis

scientific article

Growth inhibition of a colonic adenocarcinoma cell line (HT29) by T cells specific for mutant p21 ras.

scientific article published on February 1994

HLA class I and II typing using cells positively selected from blood by immunomagnetic isolation--a fast and reliable technique.

scientific article

HLA class II profile of a human carcinoma cell line: detection on genomic level and after exposure to gamma-interferon

scientific article published on 01 February 1987

HLA restriction fine-specificity and T-cell receptor usage of T cells recognizing DQ7

scientific article published on 01 April 1994

HLA-A3 restricted mutant ras specific cytotoxic T-lymphocytes induced by vaccination with T-helper epitopes

scientific article published on 13 November 2002

HLA-DQ antigens and DQ beta amino acid 57 of Japanese patients with insulin-dependent diabetes mellitus: detection of a DRw8DQw8 haplotype

scientific article

HLA-DQw3.1 and DQw3.2 associated exon polymorphisms detected by oligonucleotide probes ⬇️

scientific article published on 01 April 1988

Heterogeneity of T cells specific for a particular peptide/HLA-DQ complex

scientific article published in January 1994

Human T lymphocyte clones: influence of culture conditions and optimization of proliferative assays

scientific article published on 01 July 1989

Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3.

scientific article

Identification of nucleolar protein No55 as a tumour-associated autoantigen in patients with prostate cancer

scientific article

Identification of prostate cancer antigens by automated high-throughput filter immunoscreening

scientific article

Identification, at the genomic level, of an HLA-DR restriction element for cloned antigen-specific T4 cells

scientific article

Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma

scientific article published on 16 July 2013

Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells

scientific article published on 18 October 2016

Immunization with the light chain and the VL domain of the isologous myeloma protein 315 inhibits growth of mouse plasmacytoma MOPC315

scientific article published on 01 January 1980

Immuno-gene therapy of cancer with tumour-mRNA transfected dendritic cells

scientific article

Immunological factors influencing clinical outcome in lung cancer patients after telomerase peptide vaccination.

scientific article

Immunological studies on the blood coagulation Factor X and its warfarin-induced precursor

scientific article published on 01 March 1974

Immunological typing of acute leukaemias by rosetting with immunomagnetic beads: comparison with immunofluorescence staining

scientific article published in May 1990

Immunomagnetic isolation of cells for serological BoLA typing

scientific article published on January 1988

Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients

scientific article

Impaired in vitro survival of monocytes from patients with HIV infection

scientific article published in July 1990

Improving the efficacy of cancer immunotherapy

scientific article published on 21 January 2009

In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines

scientific article published on 06 June 2013

In vitro differentiation of human monocytes. Differences in monocyte phenotypes induced by cultivation on glass or on collagen

scientific article

In vitro replication of HIV-1 in naturally infected CD4+ T cells is inhibited by rIFN alpha 2 and by a soluble factor secreted by activated CD8+ T cells, but not by rIFN beta, rIFN gamma, or recombinant tumor necrosis factor-alpha

scientific article published on January 1, 1991

Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model

scientific article published on 05 February 2015

Independent prognostic significance of HER-2 oncoprotein expression in pN0 prostate cancer undergoing curative radiotherapy

scientific article published in May 2002

Induction of Various HLA Class II Molecules in a Human Colonic Adenocarcinoma Cell Line

scientific article published on 01 February 1987

Induction of interleukin-2 production in CD4+ and CD8+ T-cell subsets after activation via CD3 and CD2

scientific article published on 01 October 1988

Induction of tissue factor synthesis in human umbilical vein endothelial cells involves protein kinase C

scientific article published on 01 April 1992

Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab

scientific article

Influence on antibody recognition of amino acid substitutions in the cleft of HLA-DQ2 molecules. Suggestive evidence of peptide-dependent epitopes

scientific article

Intracellular events associated with inhibition of B cell activation by monoclonal antibodies to HLA class II antigens

scientific article published on 01 July 1989

Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant: Clinical and immunological responses in patients with pancreatic adenocarcinoma

scientific article

Isolation and characterization of human hematopoietic progenitor cells: an effective method for positive selection of CD34+ cells

scientific article published on 01 August 1992

Isolation of functionally active T cell receptor gamma delta-bearing lymphocytes from human peripheral blood

scientific article published in March 1989

Isolation of pure and functionally active T4 and T8 cells by positive selection with antibody-coated monosized magnetic microspheres.

scientific article published in February 1987

Isolation of pure functionally active CD8+ T cells. Positive selection with monoclonal antibodies directly conjugated to monosized magnetic microspheres

scientific article published on 01 June 1986

K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location

scientific article

K-ras mutations and HLA-DR expression in large bowel adenomas

scientific article

K-ras mutations and prognosis in large-bowel carcinomas

scientific article

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study

scientific article

Ligand-Induced Redistribution and Augmentation of Surface-Bound Myeloma Protein on MOPC315 Plasmacytoma Cells ⬇️

scientific article published on January 1, 1977

Localization of receptors and early events of phagocytosis in the macrophage ⬇️

scientific article published on October 15, 1975

Long-term follow-up of patients with resected pancreatic cancer following vaccination against mutant K-ras

scientific article

Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency

scientific article published on 3 June 2016

Memory T cells of a patient with follicular thyroid carcinoma recognize peptides derived from mutated p21 ras (Gln-->Leu61).

scientific article published in November 1992

Microcytotoxic HLA typing of cells directly isolated from blood by means of antibody-coated microspheres

scientific article published on 01 February 1987

Mutated Ras Peptides as Vaccines in Immunotherapy of Cancer ⬇️

scientific article published on January 1, 1998

Mutation analyses of KRAS exon 1 comparing three different techniques: temporal temperature gradient electrophoresis, constant denaturant capillary electrophoresis and allele specific polymerase chain reaction

scientific article

Mutation analysis of TP53 exons 5-8 by automated constant denaturant capillary electrophoresis

scientific article

Mutation detection in KRAS Exon 1 by constant denaturant capillary electrophoresis in 96 parallel capillaries

scientific article

Myeloid differentiation of purified CD34+ cells after stimulation with recombinant human granulocyte-monocyte colony-stimulating factor (CSF), granulocyte-CSF, monocyte-CSF, and interleukin-3 ⬇️

scientific article published on December 15, 1991

NK cells specifically TCR-dressed to kill cancer cells

NY-ESO-1 protein expression and humoral immune responses in prostate cancer

scientific article published in June 2004

Oncogene-derived peptides: a new class of tumor rejection antigens?

scientific article published on 01 February 1993

Overlapping epitopes encompassing a point mutation (12 Gly → Arg) in p21 ras can be recognized by HLA‐DR, ‐DP and ‐DQ restricted T cells ⬇️

scientific article published on 01 October 1993

Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA.

scientific article

Phase I/IIa clinical trial of a novel hTERT peptide vaccine in men with metastatic hormone-naive prostate cancer

scientific article

Photochemical internalization: a novel technology for delivery of macromolecules into cytosol

scientific article published in March 1999

Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma

scientific article published on 22 May 2012

Population screening of single-nucleotide polymorphisms exemplified by analysis of 8000 alleles

scientific article published in December 2002

Positive selection of Tac- (CD25) positive cells following T-cell activation. Use of immunomagnetic separation and implications for T-cell cloning

scientific article published on 01 April 1989

Positive selection of activated T cells of the T8 (CD8) sub-type by immunomagnetic separation

scientific article published on 01 July 1986

Positive selection of bone marrow-derived CD34 positive cells for possible stem cell transplantation

scientific article published on 01 February 1993

Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy

scientific article published on 18 June 2019

Preclinical evaluation of autologous dendritic cells transfected with mRNA or loaded with apoptotic cells for immunotherapy of high-risk neuroblastoma

scientific article

Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination

scientific article published on 01 June 2005

Production of BALB/c Anti-Idiotypic Antibodies Against the BALB/c Myeloma Protein 315 Does Not Require an Intact Ligand-Binding Site ⬇️

scientific article published on January 1, 1977

Prospects for vaccine therapy for pancreatic cancer

scientific article

RG1, a new murine monoclonal antibody recognizing a "supertypic" determinant on HLA-A molecules

scientific article published on March 1995

Rapid identification of human B-lymphocytes and monocytes with rhodamine-labeled Brucella melitensis

scientific article published in January 1981

Rapid immunomagnetic phenotyping of cells.

scientific article published in April 1989

Relative efficiency of human Langerhans' cells and blood derived dendritic cells as antigen-presenting cells.

scientific article published in January 1985

Reliable isolation of human immunodeficiency virus from cultures of naturally infected CD4+ T cells

scientific article published in September 1989

Requirements for phytohaemagglutinin activation of resting pure CD4+ and CD8+ T cells

scientific article published on 01 May 1988

Resolving the evolutionary paradox of genetic instability: a cost-benefit analysis of DNA repair in changing environments

scientific article published in April 2004

Retracted: Identification and Characterization of Cells with Cancer Stem Cell Properties in Human Primary Lung Cancer Cell Lines

retracted article

Role of accessory cells in the activation of pure T cells via the T cell receptor-CD3 complex or with phytohaemagglutinin

scientific article published on 01 May 1988

Role of the TCR binding region of the HLA class I alpha 2 domain in regulation of cell adhesion and proliferation

scientific article published on 01 February 1996

Serological cloning of cancer/testis antigens expressed in prostate cancer using cDNA phage surface display

scientific article

Sialomucin CD34 is the major L-selectin ligand in human tonsil high endothelial venules

scientific article

Specificity of gamma delta receptor-bearing cytotoxic T lymphocytes isolated from human peripheral blood

scientific article published in June 1989

Staphylococcal exotoxin superantigens induce human immunodeficiency virus type 1 expression in naturally infected CD4+ T cells

scientific article published on October 1992

Studies on PIVKA-X

scientific article published on November 15, 1975

Studies on the biosynthesis of factor VII (proconvertin). The mode of action of warfarin

scientific article

Successful clinical use of an anti-HLA-DR monoclonal antibody for autologous bone marrow transplantation

scientific article published on 01 October 1988

Successful induction of immune responses against mutant ras in melanoma patients using intradermal injection of peptides and GM-CSF as adjuvant.

scientific article

Suppression of T-cell proliferation by Mycobacterium leprae and its products: the role of lipopolysaccharide ⬇️

scientific article published on February 1, 1990

Synthesis of serum proteins by a clonal strain of rat hepatoma cells

scientific article published on 01 March 1973

T cell clones specific for p21 ras-derived peptides: characterization of their fine specificity and HLA restriction

scientific article published on 01 March 1993

T cell epitopes encompassing the mutational hot spot position 61 of p21 ras. Promiscuity in ras peptide binding to HLA.

scientific article published in February 1994

T cell responses against mutant ras: a basis for novel cancer vaccines ⬇️

scientific article published on February 1, 1996

T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells

article

T cell-epithelium interactions in relation to gut immunity.

scientific article published in January 1988

T cells recognizing an HLA-DQ alpha beta heterodimer encoded in cis by the DR4DQw4 haplotype and in trans by DR4DQw8/DRw8DQw4 heterozygous cells

scientific article published on 01 March 1991

T lymphocyte clones recognizing an HLA-DQw3.2-associated epitope involving residue 57 on the DQ beta chain

scientific article published on 01 August 1988

T- and B-cell-independent activation of syngeneic macrophages by murine sarcoma cells

scientific article published on 01 June 1980

T-cell recognition of HLA class II molecules induced by gamma-interferon on a colonic adenocarcinoma cell line (HT29).

scientific article published on April 1990

T-cell responses against products of oncogenes: generation and characterization of human T-cell clones specific for p21 ras-derived synthetic peptides

scientific article published on 01 April 1992

T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy

scientific article published on 24 October 2016

Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif

scientific article published on 16 September 2010

Telomerase Peptide Vaccination Combined with Temozolomide: A Clinical Trial in Stage IV Melanoma Patients ⬇️

scientific article published on May 17, 2011

Telomerase peptide vaccination in NSCLC: a phase II trial in stage III patients vaccinated after chemoradiotherapy and an 8-year update on a phase I/II trial

scientific article published on 14 September 2011

Telomerase peptide vaccination of patients with non-resectable pancreatic cancer: A dose escalating phase I/II study

scientific article

Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer

article by Paal F. Brunsvig et al published 21 February 2006 in Cancer Immunology, Immunotherapy

The Mild Inflammatory Response in Febrile Neutropenic Lymphoma Patients with Low Risk of Complications is More Pronounced in Patients Receiving Tobramycin Once Daily Compared with Three Times Daily ⬇️

scientific article published on December 1, 2011

The Plasma Cell Differentiation Antigen PC.1 is Absent in CH3/Tif and Present in C3H/HeJ ⬇️

scientific article published on January 1, 1979

The TCR-binding region of the HLA class I alpha2 domain signals rapid Fas-independent cell death: a direct pathway for T cell-mediated killing of target cells? ⬇️

scientific article published on 01 May 1998

The role of the CD8-positive subset of T cells in proliferative responses to soluble antigens. I. Studies of healthy subjects, type 1 diabetics, and coeliac disease patients

scientific article published on 01 April 1986

The role of the CD8-positive subset of T cells in proliferative responses to soluble antigens. II. CD8-positive cells are not responsible for DR-associated differences in responsiveness to mumps and Coxsackie B4.

scientific article

Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma

scientific article published on 02 July 2013

Thromboplastin (tissue factor) in plasma membranes of human monocytes

scientific article published in June 1985

Tissue thromboplastin generation in circulating mononuclear phagocytes and development of coagulation disorders during E. coli endotoxinaemia in pigs

scientific article

Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination

scientific article published on 19 January 2019

Transiently redirected T cells for adoptive transfer.

scientific article published on 21 December 2010

Unconventional cytokine profiles and development of T cell memory in long-term survivors after cancer vaccination

scientific article published on 17 February 2009

Vaccination of patients with cutaneous melanoma with telomerase-specific peptides ⬇️

scientific article published on June 17, 2011

Vaccination with mutant ras peptides and induction of T-cell responsiveness in pancreatic carcinoma patients carrying the corresponding RAS mutation

scientific article published in The Lancet

Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001 ⬇️

scientific article published on August 1, 2012

hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes ⬇️

scientific article published on March 2, 2011

mRNA transfection of DC in the immature or mature state: comparable in vitro priming of Th and cytotoxic T lymphocytes against DC electroporated with tumor cell line-derived mRNA

scientific article published on 01 January 2007

mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT) ⬇️

scientific article published on 01 January 2002

p21-ras-peptide-specific T-cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly-->Asp).

scientific article published in January 1994

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