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List of works by Gunnar von Heijne

A 12-residue-long polyleucine tail is sufficient to anchor synaptobrevin to the endoplasmic reticulum membrane

scientific article published on 01 March 1996

A 30-residue-long "export initiation domain" adjacent to the signal sequence is critical for protein translocation across the inner membrane of Escherichia coli

scientific article

A Day in the Life of Dr K. or How I Learned to Stop Worrying and Love Lysozyme: a tragedy in six acts.

scientific article

A biphasic pulling force acts on transmembrane helices during translocon-mediated membrane integration

scientific article published on 23 September 2012

A conserved cleavage-site motif in chloroplast transit peptides

scientific article published on 01 February 1990

A de novo designed signal peptide cleavage cassette functions in vivo

scientific article published on 01 February 1991

A global topology map of the Saccharomyces cerevisiae membrane proteome

scholarly article

A nascent secretory protein may traverse the ribosome/endoplasmic reticulum translocase complex as an extended chain

scientific article

A neural network method for identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

scientific article published in October 1997

A new method for predicting signal sequence cleavage sites

scientific article (publication date: 11 June 1986)

A nine-transmembrane domain topology for presenilin 1

scientific article

A quantitative assay to determine the amount of signal peptidase I in E. coli and the orientation of membrane vesicles.

scientific article

A receptor component of the chloroplast protein translocation machinery

scientific article published in December 1994

A sequence correlation between oppositely charged residues in secreted proteins

scientific article published on 01 March 1980

A short C-terminal tail prevents mis-targeting of hydrophobic mitochondrial membrane proteins to the ER

article published in 2013

A signal peptide with a proline next to the cleavage site inhibits leader peptidase when present in a sec -independent protein

scientific article published on 01 March 1992

A study of the membrane-water interface region of membrane proteins.

scientific article

A theoretical study of the attenuation control mechanism

scientific article published in July 1982

A turn propensity scale for transmembrane helices

scientific article published on 01 April 1999

Ala-insertion scanning mutagenesis of the glycophorin A transmembrane helix: a rapid way to map helix-helix interactions in integral membrane proteins

scientific article published on July 1996

Alanine Insertion Scanning Mutagenesis of Lactose Permease Transmembrane Helices ⬇️

scientific article published on November 21, 1997

Amino acid distributions around O-linked glycosylation sites

scientific article published on April 1991

Analysis of transmembrane helix integration in the endoplasmic reticulum in S. cerevisiae

scientific article published in March 2009

Anionic phospholipids are determinants of membrane protein topology

scientific article published on July 1997

Antiparallel dimers of the small multidrug resistance protein EmrE are more stable than parallel dimers

scientific article

Apolar surface area determines the efficiency of translocon-mediated membrane-protein integration into the endoplasmic reticulum

scientific article

Application of split-green fluorescent protein for topology mapping membrane proteins in Escherichia coli

scientific article published on 21 August 2012

Architecture of helix bundle membrane proteins: an analysis of cytochrome c oxidase from bovine mitochondria

scientific article published on April 1997

Architecture of β‐barrel membrane proteins: Analysis of trimeric porins ⬇️

scientific article published on September 1, 1998

Arginine in membranes: the connection between molecular dynamics simulations and translocon-mediated insertion experiments

scientific article

Asn- and Asp-mediated interactions between transmembrane helices during translocon-mediated membrane protein assembly

scientific article

Assembly of a cytoplasmic membrane protein in Escherichia coli is dependent on the signal recognition particle.

scientific article

Assembly of the cytochrome bo3 complex

scientific article published on 21 May 2007

Astrotactins 1 and 2 have similar membrane topology and mature via endoproteolytic cleavage catalyzed by signal peptidase

BIOGENESIS OF INNER MEMBRANE PROTEINS IN ESCHERICHIA COLI

scientific article published on 01 January 2005

Biological insertion of computationally designed short transmembrane segments

scientific article published on 18 March 2016

Breaking the camel's back: proline-induced turns in a model transmembrane helix

scientific article published on 01 December 1998

CHLPEP—A database of chloroplast transit peptides

scholarly article by Gunnar von Heijne et al published May 1991 in Plant Molecular Biology Reporter

Calnexin can interact with N-linked glycans located close to the endoplasmic reticulum membrane

scientific article

Central functions of the lumenal and peripheral thylakoid proteome of Arabidopsis determined by experimentation and genome-wide prediction

scientific article

Chapter 10 Analysis and prediction of mitochondrial targeting peptides

article

Charge pair interactions in a model transmembrane helix in the ER membrane

scientific article published on 01 October 2000

Charge-driven dynamics of nascent-chain movement through the SecYEG translocon

scientific article published on 5 January 2015

Charged flanking residues control the efficiency of membrane insertion of the first transmembrane segment in yeast mitochondrial Mgm1p

scientific article published on 30 March 2011

ChloroP, a neural network-based method for predicting chloroplast transit peptides and their cleavage sites

scientific article (publication date: May 1999)

Chloroplast transit peptides from the green alga Chlamydomonas reinhardtii share features with both mitochondrial and higher plant chloroplast presequences

scientific article published in January 1990

Chloroplast transit peptides the perfect random coil?

scientific article published on 01 January 1991

Cleavage of a tail-anchored protein by signal peptidase

scientific article published in April 2002

Cleavage-site motifs in mitochondrial targeting peptides

scientific article published on 01 October 1990

Comparative analysis of amino acid distributions in integral membrane proteins from 107 genomes

scientific article published on September 2005

Competition between Sec- and TAT-dependent protein translocation in Escherichia coli

scientific article

Competition between neighboring topogenic signals during membrane protein insertion into the ER

article

Competition between neighboring topogenic signals during membrane protein insertion into the ER

scientific article published on 01 January 2005

Consensus predictions of membrane protein topology

scientific article published on 01 December 2000

Contribution of hydrophobic and electrostatic interactions to the membrane integration of the Shaker K+ channel voltage sensor domain.

scholarly article

Contribution of positively charged flanking residues to the insertion of transmembrane helices into the endoplasmic reticulum

scholarly article

Control of membrane protein topology by a single C-terminal residue

scientific article

Converting a marginally hydrophobic soluble protein into a membrane protein

scientific article published on 22 January 2011

Coordinated disassembly of the divisome complex in Escherichia coli

scientific article

Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125

scientific article

Cotranslational Folding of a Pentarepeat β-Helix Protein

scientific article published on 27 October 2018

Cotranslational Protein Folding inside the Ribosome Exit Tunnel

scientific article

Cotranslational folding cooperativity of contiguous domains of α-spectrin

scientific article published on 08 June 2020

Cotranslational folding of a pentarepeat β-helix protein

Cotranslational folding of alkaline phosphatase in the periplasm of Escherichia coli

scientific article published on 13 August 2020

Cotranslational folding of membrane proteins probed by arrest-peptide-mediated force measurements

scientific article published on 19 August 2013

Cotranslational folding of spectrin domains via partially structured states

scientific article published on 23 January 2017

De novo design of integral membrane proteins

scientific article published in December 1994

Defining a similarity threshold for a functional protein sequence pattern: the signal peptide cleavage site

scientific article

Detecting sequence signals in targeting peptides using deep learning

scientific article published on 30 September 2019

Determinants of topogenesis and glycosylation of type II membrane proteins. Analysis of Na,K-ATPase beta 1 AND beta 3 subunits by glycosylation mapping

scientific article published in September 2000

Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits

scientific article

Determination of the Border between the Transmembrane and Cytoplasmic Domains of Human Integrin Subunits

scientific article published in Journal of Biological Chemistry

Determination of the membrane topology of Ost4p and its subunit interactions in the oligosaccharyltransferase complex in Saccharomyces cerevisiae

scientific article

Different conformations of nascent polypeptides during translocation across the ER membrane

scientific article

Different positively charged amino acids have similar effects on the topology of a polytopic transmembrane protein in Escherichia coli ⬇️

scientific article published on January 25, 1992

Different sec-requirements for signal peptide cleavage and protein translocation in a model E. coli protein.

scientific article

Differential repositioning of the second transmembrane helices from E. coli Tar and EnvZ upon moving the flanking aromatic residues

scientific article

Differential use of the signal recognition particle translocase targeting pathway for inner membrane protein assembly in Escherichia coli

scientific article published on December 1998

Direct Detection of Membrane-Inserting Fragments Defines the Translocation Pores of a Family of Pathogenic Toxins

scientific article published on 07 July 2018

Directionality in protein translocation across membranes: the N-tail phenomenon.

scientific article

Disassembly of the divisome in Escherichia coli: evidence that FtsZ dissociates before compartmentalization

scientific article published on 20 February 2014

Dislocation by the m-AAA protease increases the threshold hydrophobicity for retention of transmembrane helices in the inner membrane of yeast mitochondria

scientific article published on 2 January 2013

Distant downstream sequence determinants can control N-tail translocation during protein insertion into the endoplasmic reticulum membrane

scientific article published on 01 March 2000

Disulfide bond formation and cysteine exclusion in gram-positive bacteria

scientific article published on 24 November 2009

Divergent evolution of membrane protein topology: the Escherichia coli RnfA and RnfE homologues

scientific article published on July 1999

Do protein-lipid interactions determine the recognition of transmembrane helices at the ER translocon?

scientific article published in November 2005

Dynamic membrane topology in an unassembled membrane protein

scientific article published on 09 September 2019

Early evolution of cellular electron transport: molecular models for the ferredoxin-rubredoxin-flavodoxin region

scientific article published in September 1978

Effect of acute hyperketonemia on the cerebral uptake of ketone bodies in nondiabetic subjects and IDDM patients.

scientific article

Effects of 'hydrophobic mismatch' on the location of transmembrane helices in the ER membrane

scientific article

Effects of protein size, thermodynamic stability, and net charge on cotranslational folding on the ribosome

article published in the Proceedings of the National Academy of Sciences of the United States of America

Effects of protein size, thermodynamic stability, and net charge on cotranslational folding on the ribosome

Efficient glycosylphosphatidylinositol (GPI) modification of membrane proteins requires a C-terminal anchoring signal of marginal hydrophobicity

scientific article published on 19 March 2012

Emulating membrane protein evolution by rational design

scientific article published in Science

Energetics of side-chain snorkeling in transmembrane helices probed by nonproteinogenic amino acids

scientific article published on 06 September 2016

Estimating Z-ring radius and contraction in dividing Escherichia coli

scientific article published on 10 February 2010

Evidence for a protein transported through the secretory pathway en route to the higher plant chloroplast

scientific article published on 13 November 2005

Experimentally based topology models for E. coli inner membrane proteins

scientific article published in April 2004

Experimentally constrained topology models for 51,208 bacterial inner membrane proteins

scientific article published on September 2005

Exploration of the arrest peptide sequence space reveals arrest-enhanced variants

scientific article published on 24 February 2015

Expression of an olfactory receptor in Escherichia coli: purification, reconstitution, and ligand binding.

scientific article

Fast Needleman-Wunsch scanning of sequence databanks on a massively parallel computer

scientific article published on February 1993

Feature-based prediction of non-classical and leaderless protein secretion

scientific article

Feature-extraction from endopeptidase cleavage sites in mitochondrial targeting peptides

scientific article published on 01 January 1998

Features of transmembrane segments that promote the lateral release from the translocase into the lipid phase

scientific article published on 04 December 2007

Fine-tuning the topology of a polytopic membrane protein: role of positively and negatively charged amino acids.

scientific article

Flanking residues help determine whether a hydrophobic segment adopts a monotopic or bitopic topology in the endoplasmic reticulum membrane

scientific article published on 23 May 2011

Folding pathway of an Ig domain is conserved on and off the ribosome

article published in the Proceedings of the National Academy of Sciences of the United States of America

Forces on Nascent Polypeptides during Membrane Insertion and Translocation via the Sec Translocon

scientific article published on 10 October 2018

Forcing the issue: aromatic tuning facilitates stimulus-independent modulation of a two-component signaling circuit

scientific article published on 9 September 2014

Formation of cytoplasmic turns between two closely spaced transmembrane helices during membrane protein integration into the ER membrane

scientific article published on 01 August 2000

Formation of helical hairpins during membrane protein integration into the endoplasmic reticulum membrane. Role of the N and C-terminal flanking regions

scientific article published in November 2001

Formation of transmembrane helices in vivo--is hydrophobicity all that matters?

scientific article published on 16 April 2007

Functionality of the voltage-gated proton channel truncated in S4

scientific article

GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae

scientific article published on January 2008

Genome‐wide analysis of integral membrane proteins from eubacterial, archaean, and eukaryotic organisms ⬇️

scientific article published on April 1, 1998

Getting sense out of sequence data

scientific article

Global profiling of SRP interaction with nascent polypeptides.

scientific article published on 3 August 2016

Global topology analysis of the Escherichia coli inner membrane proteome

scientific article

Glycosylatable GFP as a compartment-specific membrane topology reporter

scientific article

Glycosylation efficiency of Asn-Xaa-Thr sequons depends both on the distance from the C terminus and on the presence of a downstream transmembrane segment

scientific article published on 01 June 2000

Green fluorescent protein as an indicator to monitor membrane protein overexpression in Escherichia coli

scientific article published on 01 October 2001

Helical sidedness and the distribution of polar residues in trans-membrane helices

scientific article published in July 1983

Helices on the move

scientific article published on 01 October 2005

Helix-helix packing in a membrane-like environment ⬇️

scientific article published on October 3, 1997

High-throughput fluorescent-based optimization of eukaryotic membrane protein overexpression and purification in Saccharomyces cerevisiae

scholarly article

Homology to region X from staphylococcal protein A is not unique to cell surface proteins

scientific article published on 01 August 1987

How hydrophobic is alanine?

scientific article published on 20 May 2003

How proteins adapt to a membrane-water interface

scientific article

How proteins insert into the ER membrane

How signal sequences maintain cleavage specificity

scientific article published on 01 February 1984

How translocons select transmembrane helices

scientific article published on January 2008

Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function

scientific article

Hydrophobic Clusters Raise the Threshold Hydrophilicity for Insertion of Transmembrane Sequences in Vivo

scientific article

Hydrophobic blocks facilitate lipid compatibility and translocon recognition of transmembrane protein sequences

scientific article published on 12 February 2015

Identification and evolution of dual-topology membrane proteins

scientific article published on 22 January 2006

Identification of novel sphingolipid-binding motifs in mammalian membrane proteins

scientific article published on 2 May 2014

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

scientific article (publication date: 1997)

Improved detection of homologous membrane proteins by inclusion of information from topology predictions.

scientific article

Improved membrane protein topology prediction by domain assignments

scientific article published on July 2005

Improved prediction of signal peptides: SignalP 3.0

scientific article (publication date: 16 July 2004)

Improved production of membrane proteins in Escherichia coli by selective codon substitutions

scientific article published on 12 June 2013

In sequence

scientific article published in Nature

In silico prediction of the peroxisomal proteome in fungi, plants and animals.

scientific article

In vitro membrane integration of leader peptidase depends on the Sec machinery and anionic phospholipids and can occur post‐translationally ⬇️

scientific article published on August 11, 1997

In vivo trp scanning of the small multidrug resistance protein EmrE confirms 3D structure models'.

scientific article

Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway

scientific article published on January 2014

Inhibition of protein translocation across the endoplasmic reticulum membrane by sterols

scientific article

Insertion and topology of a plant viral movement protein in the endoplasmic reticulum membrane

scientific article published on 25 April 2002

Insertion of a bacterial secondary transport protein in the endoplasmic reticulum membrane

scientific article published on 01 January 1999

Insertion of short transmembrane helices by the Sec61 translocon

scholarly article

Inter-helical hydrogen bond formation during membrane protein integration into the ER membrane.

scientific article published in December 2003

Interface connections of a transmembrane voltage sensor

scientific article

Introduction to Theme “Membrane Protein Folding and Insertion” ⬇️

scientific article published on January 1, 2011

Kinetic aspects of the DNA helix - cruciform transition

scientific article published on 01 December 1976

Large tilts in transmembrane helices can be induced during tertiary structure formation.

scientific article published on 30 April 2014

Lipid Bilayers, Translocons and the Shaping of Polypeptide Structure

Locating proteins in the cell using TargetP, SignalP and related tools

scientific article (publication date: 2007)

LumenP—A neural network predictor for protein localization in the thylakoid lumen ⬇️

scientific article published on October 1, 2003

Machine learning approaches for the prediction of signal peptides and other protein sorting signals

scientific article

Manipulating the genetic code for membrane protein production: what have we learnt so far?

scientific article published on 22 August 2011

Mapping the interaction of the STT3 subunit of the oligosaccharyl transferase complex with nascent polypeptide chains

scientific article published on 10 October 2005

Mechanisms of integral membrane protein insertion and folding

scientific article

Membrane Insertion of Marginally Hydrophobic Transmembrane Helices Depends on Sequence Context

article published in 2010

Membrane assembly of the cannabinoid receptor 1: impact of a long N-terminal tail

scientific article published in September 2003

Membrane insertion of a potassium-channel voltage sensor

scientific article

Membrane permeability

Membrane protein anchors and polytopic determinants

scientific article published in November 1995

Membrane protein assembly

Membrane protein assembly in vivo

scientific article

Membrane protein assembly: rules of the game

scientific article

Membrane protein structural biology--how far can the bugs take us?

scientific article published on September 2007

Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule

scientific article (publication date: 20 May 1992)

Membrane protein structure: prediction versus reality.

scientific article

Membrane protein topogenesis in Escherichia coli

scholarly article published 1995

Membrane protein topology: effects of delta mu H+ on the translocation of charged residues explain the 'positive inside' rule.

scientific article published on May 1994

Membrane proteins up for grabs

scientific article published in June 2007

Membrane proteins: from bench to bits ⬇️

scientific article published on June 1, 2011

Membrane proteins: from sequence to structure

scientific article

Membrane proteins: shaping up.

scientific article

Membrane topology mapping of vitamin K epoxide reductase by in vitro translation/cotranslocation

scientific article published on 16 February 2005

Membrane topology of the 60-kDa Oxa1p homologue from Escherichia coli.

scientific article published in November 1998

Membrane topology of the Drosophila OR83b odorant receptor

scientific article published on 20 November 2007

Membrane topology of the STT3 subunit of the oligosaccharyl transferase complex

scientific article published on 21 March 2005

Membrane topology of the human seipin protein

scholarly article by Carolina Boekel published in March 2006

Membrane-integration characteristics of two ABC transporters, CFTR and P-glycoprotein

scientific article published on 21 February 2009

Membrane-protein engineering

scientific article published on October 1997

Membrane-protein topology

scientific article

Membranes: reading between the lines.

scientific article

Mitochondrial targeting sequences. Why 'non-amphiphilic' peptides may still be amphiphilic

scientific article published on 01 August 1988

Models for mRNA translation: theory versus experiment

scientific article published on December 1978

Molecular code for protein insertion in the endoplasmic reticulum membrane is similar for N(in)-C(out) and N(out)-C(in) transmembrane helices

scholarly article

Molecular code for transmembrane-helix recognition by the Sec61 translocon

scientific article published in December 2007

Molecular mechanism of membrane protein integration into the endoplasmic reticulum

scientific article published on 01 May 1997

Molecular recognition of a single sphingolipid species by a protein's transmembrane domain

scientific article published on 9 January 2012

Murine astrotactins 1 and 2 have a similar membrane topology and mature via endoproteolytic cleavage catalyzed by a signal peptidase

scientific article published on 29 January 2019

Mutational analysis of the human Xbp1 translational arrest peptide and construction of arrest-enhanced variants

N-Tail translocation in a eukaryotic polytopic membrane protein. Synergy between neighboring transmembrane segments

article

Net N-C charge imbalance may be important for signal sequence function in bacteria

scientific article published on 01 November 1986

New Escherichia coli outer membrane proteins identified through prediction and experimental verification

scientific article

On the emergence of new function in primitive proteins

scientific article published on 01 November 1978

Orientational preferences of neighboring helices can drive ER insertion of a marginally hydrophobic transmembrane helix

scientific article published on 25 January 2012

PONGO: a web server for multiple predictions of all-alpha transmembrane proteins

scientific article published on July 2006

Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae

scholarly article

Phosphatidylethanolamine mediates insertion of the catalytic domain of leader peptidase in membranes

scientific article

Photocross-linking of nascent chains to the STT3 subunit of the oligosaccharyltransferase complex

scientific article

Position-specific Asp-Lys pairing can affect signal sequence function and membrane protein topology

scientific article published on 01 October 1993

Positional editing of transmembrane domains during ion channel assembly

scientific article published on 10 December 2012

Positively and negatively charged residues have different effects on the position in the membrane of a model transmembrane helix

scientific article published on 01 December 1998

Positively charged amino acids placed next to a signal sequence block protein translocation more efficiently in Escherichia coli than in mammalian microsomes

scientific article published on 01 May 1993

Positively charged residues influence the degree of SecA dependence in protein translocation across the E. coli inner membrane

scientific article published on 01 June 1994

Predicting subcellular localization of proteins based on their N-terminal amino acid sequence

scientific article (publication date: 21 July 2000)

Predicting the topology of eukaryotic membrane proteins

scientific article published on 01 May 1993

Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

scientific article (publication date: 19 January 2001)

Prediction of N-terminal protein sorting signals

scientific article

Prediction of lipoprotein signal peptides in Gram-negative bacteria

scientific article published on August 2003

Prediction of membrane-protein topology from first principles

scholarly article

Prediction of organellar targeting signals

scientific article

Prediction of partial membrane protein topologies using a consensus approach.

scientific article

Prediction of the human membrane proteome

scientific article published in March 2010

Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method ⬇️

scientific article (publication date: June 1997)

Principles of membrane protein assembly and structure

scientific article published on January 1996

Production of human tetraspanin proteins in Escherichia coli

scientific article

Proline kinks in transmembrane alpha-helices

scientific article published in April 1991

Proline-induced disruption of a transmembrane alpha-helix in its natural environment

scientific article published in December 1998

Properties of N-terminal tails in G-protein coupled receptors: a statistical study

scientific article published on 01 July 1995

Protein complexes of the Escherichia coli cell envelope.

scientific article published on 3 August 2005

Protein targeting signals

scientific article published on August 1990

Proteomics. Tissue-based map of the human proteome

scientific article (publication date: 23 January 2015)

Quantitative analysis of SecYEG-mediated insertion of transmembrane α-helices into the bacterial inner membrane

scientific article published on 7 May 2013

RIFINs are adhesins implicated in severe Plasmodium falciparum malaria

scientific article (publication date: April 2015)

RNA splicing: Advantages of parallel processing

Rapid topology mapping of Escherichia coli inner-membrane proteins by prediction and PhoA/GFP fusion analysis

scientific article

Recent advances in the understanding of membrane protein assembly and structure

scientific article

Recognition of transmembrane helices by the endoplasmic reticulum translocon.

scientific article published on January 2005

Reliability measures for membrane protein topology prediction algorithms

scientific article

Repositioning of transmembrane alpha-helices during membrane protein folding

scientific article published on 25 January 2010

Ribosome-SRP-signal sequence interactions. The relay helix hypothesis

scientific article

Sec dependent and sec independent assembly of E. coli inner membrane proteins: the topological rules depend on chain length

scientific article

Sec-independent protein insertion into the inner E. coli membrane. A phenomenon in search of an explanation

scientific article

Sec-independent translocation of a 100-residue periplasmic N-terminal tail in the E. coli inner membrane protein proW.

scientific article published on October 1994

SecA-dependence of the translocation of a large periplasmic loop in the Escherichia coli MalF inner membrane protein is a function of sequence context

SecA-independent translocation of the periplasmic N-terminal tail of an Escherichia coli inner membrane protein. Position-specific effects on translocation of positively charged residues and construction of a protein with a C-terminal translocation s

scientific article published in Journal of Biological Chemistry

Sequence determinants of cytosolic N-terminal protein processing

scientific article published in January 1986

Sequence differences between glycosylated and non-glycosylated Asn-X-Thr/Ser acceptor sites: implications for protein engineering

scientific article published on 01 April 1990

Sequence-based feature prediction and annotation of proteins

scientific article (publication date: 2009)

Sequential closure of the cytoplasm and then the periplasm during cell division in Escherichia coli

scientific article published on 18 November 2011

Signal peptidases in prokaryotes and eukaryotes--a new protease family

scientific article published on November 1992

Signal sequences are not uniformly hydrophobic

scientific article published on 01 August 1982

Signal survey

scientific article published in Nature

SignalP 4.0: discriminating signal peptides from transmembrane regions

scientific article (publication date: 29 September 2011)

Small protein domains fold inside the ribosome exit tunnel

scientific article published on 16 February 2016

Somatic acquisition and signaling of TGFBR1*6A in cancer

scientific article

Some global ?-sheet characterstics

scientific article published in 1978

Spontaneous transmembrane helix insertion thermodynamically mimics translocon-guided insertion

scientific article

Stable Membrane Topologies Of Small Dual-Topology Membrane Proteins

Stable insertion of Alzheimer Abeta peptide into the ER membrane strongly correlates with its length

scientific article published on 19 July 2007

Stable membrane orientations of small dual-topology membrane proteins

scientific article

Stop-transfer efficiency of marginally hydrophobic segments depends on the length of the carboxy-terminal tail

scientific article published on February 2003

Stop‐transfer function of pseudo‐random amino acid segments during translocation across prokaryotic and eukaryotic membranes ⬇️

scientific article published on 01 February 1998

Structural and mutational analysis of the ribosome-arresting human XBP1u.

scientific article published on 27 June 2019

Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide

scientific article

Structures of N-terminally acetylated proteins

scientific article published in 1985

Synergistic insertion of two hydrophobic regions drives Sec-independent membrane protein assembly

scientific article published on 01 October 1994

TIM23-mediated insertion of transmembrane α-helices into the mitochondrial inner membrane.

scientific article

The 'positive-inside rule' applies to thylakoid membrane proteins

scientific article

The COOH-terminal ends of internal signal and signal-anchor sequences are positioned differently in the ER translocase

scientific article

The Dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 gene

scientific article

The DsbA-DsbB system affects the formation of disulfide bonds in periplasmic but not in intramembraneous protein domains.

scientific article

The Escherichia coli SRP and SecB targeting pathways converge at the translocon

scientific article published on May 1998

The Shape of the Ribosome Exit Tunnel Affects Cotranslational Protein Folding

The Use of Phylogenetic Profiles for Gene Predictions Revisited

scholarly article by Asa Bjorklund et al published 1 April 2006 in Current Genomics

The aromatic residues Trp and Phe have different effects on the positioning of a transmembrane helix in the microsomal membrane.

scientific article

The code for directing proteins for translocation across ER membrane: SRP cotranslationally recognizes specific features of a signal sequence.

scientific article

The concentration dependence of the error frequencies and some related quantities in protein synthesis ⬇️

scientific article published on 01 May 1979

The cytoplasmic domain of Escherichia coli leader peptidase is a "translocation poison" sequence

scientific article

The distribution of charged amino acids in mitochondrial inner-membrane proteins suggests different modes of membrane integration for nuclearly and mitochondrially encoded proteins

scientific article

The efficiency of the uncleaved secretion signal in the plasminogen activator inhibitor type 2 protein can be enhanced by point mutations that increase its hydrophobicity

scientific article published on 01 August 1991

The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling

scientific article published on 30 May 2017

The internal repeats in the Na+/Ca2+ exchanger-related Escherichia coli protein YrbG have opposite membrane topologies

scientific article

The leader peptides from bacteriorhodopsin and halorhodopsin are potential membrane-spanning amphipathic helices

scientific article published on 01 March 1987

The machinery of membrane protein assembly

scientific article published in August 2004

The membrane protein universe: what's out there and why bother?

scientific article published on June 2007

The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding.

scientific article published on 26 November 2018

The signal peptide

scientific article published on May 1990

The signal recognition particle-targeting pathway does not necessarily deliver proteins to the sec-translocase in Escherichia coli

scientific article published on 01 July 1999

The structure of signal peptides from bacterial lipoproteins

scientific article published on 01 May 1989

The tRNA cycle and its relation to the rate of protein synthesis

scientific article published in January 1985

The topogenic function of S4 promotes membrane insertion of the voltage-sensor domain in the KvAP channel

scientific article published on 30 September 2016

The β structure: Inter-strand correlations ⬇️

scientific article published on December 15, 1977

Theoretical modelling of protein synthesis

scientific article published on March 1987

Thermodynamics of Membrane Insertion and Refolding of the Diphtheria Toxin T-Domain

scientific article

Three-dimensional model for the membrane domain of Escherichia coli leader peptidase based on disulfide mapping.

scientific article

Today's data

scientific article published in Nature

TopPred II: an improved software for membrane protein structure predictions

scientific article (publication date: December 1994)

Topogenic signals in integral membrane proteins

scientific article

Topological "frustration" in multispanning E. coli inner membrane proteins.

scientific article published in May 1994

Topological rules for membrane protein assembly in eukaryotic cells

scientific article published in Journal of Biological Chemistry

Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions

scientific article

Topology of the Membrane-Associated Hepatitis C Virus Protein NS4B

scientific article

Topology, subcellular localization, and sequence diversity of the Mlo family in plants

scientific article published on 01 December 1999

Towards a comparative anatomy of N-terminal topogenic protein sequences

scientific article published on 01 May 1986

Trans-membrane Translocation of Proteins. The Direct Transfer Model ⬇️

scientific article published on June 1, 1979

Transcending the impenetrable: how proteins come to terms with membranes

scientific article published on June 1988

Translation and messenger RNA secondary structure ⬇️

scientific article published on 01 October 1977

Translation rate modification by preferential codon usage: intragenic position effects.

scientific article

Transmembrane but not soluble helices fold inside the ribosome tunnel

scientific article published in Nature Communications

Transmembrane helices before, during, and after insertion

scientific article

Transmembrane helices containing a charged arginine are thermodynamically stable

scientific article published on 13 April 2017

Trigger Factor Reduces the Force Exerted on the Nascent Chain by a Cotranslationally Folding Protein

scientific article published on 18 February 2016

Turns in transmembrane helices: determination of the minimal length of a “helical hairpin” and derivation of a fine-grained turn propensity scale 1 1Edited by F. E. Cohen

Weak pulling forces exerted on Nin-orientated transmembrane segments during co-translational insertion into the inner membrane of Escherichia coli.

scientific article

Why have small multidrug resistance proteins not evolved into fused, internally duplicated structures?

scientific article published on 30 March 2014

Why mitochondria need a genome

scientific article published on March 1986

YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase

scientific article

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