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List of works by Laura Lee Kiessling

A General Synthetic Route to Defined, Biologically Active Multivalent Arrays

scientific article published in 1999

A Higher Degree of Difficulty

A defined glycosaminoglycan-binding substratum for human pluripotent stem cells

scientific article

A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN.

scientific article

A polymer scaffold for protein oligomerization

scientific article published on February 2004

A polymeric domain that promotes cellular internalization

scientific article published on 8 April 2008

A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site.

scientific article published on 3 February 2012

A strategy for the synthesis of sulfated peptides

scientific article published in September 2002

A symposium in honor of Peter B. Dervan, the 2014 ACS Chemical Biology Lectureship Award Winner

scientific article published in June 2014

A tethering mechanism for length control in a processive carbohydrate polymerization

scientific article

A unique catalytic mechanism for UDP-galactopyranose mutase

scientific article

Activating B Cell Signaling with Defined Multivalent Ligands

article

Advancing Chemical Microbiology

scientific article published on 01 May 2020

Affinity-Based Inhibition of β-Amyloid Toxicity†

article

An asymmetric synthesis of L-pyrrolysine

scientific article published on 6 March 2012

Angiomotin Regulates YAP Localization during Neural Differentiation of Human Pluripotent Stem Cells

Antigen structure affects cellular routing through DC-SIGN

scientific article published on 03 July 2019

Arrays for the combinatorial exploration of cell adhesion

scientific article published on September 2004

Bacterial Cell Wall Modification with a Glycolipid Substrate

scientific article published on 04 June 2019

Bifunctional ligands that target cells displaying the alpha v beta3 integrin

scientific article published on January 2007

Bioactive Polymers

Bioconjugates and Chemical Biology

scientific article published on 01 June 2016

Biologically Active Polymers

Carbohydrate-Aromatic Interactions in Proteins

scientific article

Carbohydrate-Lectin Interactions Reprogram Dendritic Cells to Promote Type 1 Anti-Tumor Immunity

scientific article published on 16 September 2024

Carboxylate Surrogates Enhance the Antimycobacterial Activity of UDP-Galactopyranose Mutase Probes

scientific article

Cell Aggregation by Scaffolded Receptor Clusters

scientific article published on 01 February 2002

Chapter 29. Principles for multivalent ligand design

article by Laura Lee Kiessling et al published 2000 in Annual Reports in Medicinal Chemistry

ChemInform Abstract: Glycopolymer Probes of Signal Transduction

ChemInform Abstract: Glycosyl Sulfonylcarbamates: New Glycosyl Donors with Tunable Reactivity

ChemInform Abstract: p-Methoxybenzyl Ether Cleavage by Polymer-Supported Sulfonamides

ChemRXiv: A Chemistry Preprint Server

scientific article published on 01 October 2016

ChemRXiv: A Chemistry Preprint Server

scientific article

Chemical approaches to glycobiology

scientific article published on January 2010

Chemical probes of UDP-galactopyranose mutase

scientific article

Chemical probes of bacterial signal transduction reveal that repellents stabilize and attractants destabilize the chemoreceptor array

scientific article

Chemistry-driven glycoscience

scientific article published on 22 September 2018

Chemistry. A path to complex carbohydrates

scientific article published on July 2013

Chemoselective, Postpolymerization Modification of Bioactive, Degradable Polymers

scientific article published on 22 January 2019

Classifying chemoreceptors: quantity versus quality.

scientific article

Classifying chemoreceptors: quantity versus quality.

scientific article published on October 2010

Comparing Galactan Biosynthesis in Mycobacterium tuberculosis and Corynebacterium diphtheriae

scientific article published on 30 December 2016

Conformational Control of UDP-Galactopyranose Mutase Inhibition

scientific article published on 13 June 2017

Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures

scientific article

Confronting Racism in Chemistry Journals

scientific article published on 19 June 2020

Confronting Racism in Chemistry Journals

Conserved amplification of chemotactic responses through chemoreceptor interactions

scientific article published on September 2002

Contrast Agents for Magnetic Resonance Imaging Synthesized with Ring-Opening Metathesis Polymerization

scientific article published in 2006

Control of Multivalent Interactions by Binding Epitope Density

scientific article published on 01 February 2002

Controlling Cellular Responses with Multivalent Ligands

article

Convergent synthesis of sulfated bivalent glycopeptides as selectin ligands

Correction to New Insights into Bacterial Chemoreceptor Array Structure and Assembly from Electron Cryotomography.

scientific article published on 2 October 2014

Decoding signals with chemical biology.

scientific article

Defined substrates for human embryonic stem cell growth identified from surface arrays

scientific article published on 04 May 2007

Deleterious Consequences of UDP-Galactopyranose Mutase Inhibition for Nematodes

scientific article published on 21 July 2017

Fidelity and Promiscuity of a Mycobacterial Glycosyltransferase

scientific article

Fighting the Coronavirus Outbreak

scientific article published on 01 April 2020

Flanking sequence effects within the pyrimidine triple-helix motif characterized by affinity cleaving

scientific article published on March 17, 1992

Flow cytometry reveals that multivalent chemoattractants effect swarmer cell dedifferentiation

scientific article published on October 2009

Fluorescence Anisotropy Assays Reveal Affinities of C- and O-Glycosides for Concanavalin A(1)

scientific article published on 01 January 1996

Fluorosugar chain termination agents as probes of the sequence specificity of a carbohydrate polymerase

scientific article

Focus on Epigenetics

scientific article published in March 2016

Forces of Change: Mechanics Underlying Formation of Functional 3D Organ Buds

scientific article published on May 2015

Fostering Major Breakthroughs

scientific article published on 01 February 2006

General synthetic route to cell-permeable block copolymers via ROMP.

scientific article published on June 2009

Glycan-Modified Virus-Like Particles Evoke T Helper Type 1-Like Immune Responses

scientific article published on 06 August 2020

Glycomimetic building blocks: a divergent synthesis of epimers of shikimic acid

scientific article

Glycopolymer probes of signal transduction

scientific article published on 18 April 2013

Glycoprotein-inspired materials promote the proteolytic release of cell surface l-Selectin

scientific article published on 01 August 1998

Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal

scientific article published on October 2012

High-throughput discovery of synthetic surfaces that support proliferation of pluripotent cells

scientific article

Hitting the sweet spot

scientific article published on 01 March 2002

How many human proteoforms are there?

scientific article published in February 2018

Hydrolysis of Double-Stranded and Single-Stranded RNA in Hairpin Structures by the Copper(II) Macrocycle Cu([9]aneN(3))Cl(2)

scientific article published on 01 April 1997

Identification of inhibitors for UDP-galactopyranose mutase

scientific article

Imaging mycobacterial growth and division with a fluorogenic probe.

scientific article published on 27 April 2018

Improved chemical syntheses of 1- and 5-deazariboflavin

scientific article published in April 2004

Influencing Receptor−Ligand Binding Mechanisms with Multivalent Ligand Architecture

scientific article published on 01 December 2002

Inhibitors of UDP-galactopyranose mutase thwart mycobacterial growth.

scientific article published in May 2008

Inter-receptor communication through arrays of bacterial chemoreceptors

scientific article

Isoprenoid phosphonophosphates as glycosyltransferase acceptor substrates

scientific article published on 10 June 2014

Isotope-coded affinity tags with tunable reactivities for protein footprinting.

scientific article published on January 2008

Large increases in attractant concentration disrupt the polar localization of bacterial chemoreceptors.

scientific article

Ligand Binding and Substrate Discrimination by UDP-Galactopyranose Mutase

scientific article

Link between chemotactic response to Ni2+ and its adsorption onto the Escherichia coli cell surface

scientific article published in July 2005

Modular Polymer Antigens To Optimize Immunity

scientific article published on 11 November 2019

Monitoring processivity and length control of a carbohydrate polymerase

scientific article

Multivalency in Protein-Carbohydrate Recognition

Multivalency in Protein-Carbohydrate Recognition

Multivalent Antigens for Promoting B and T Cell Activation.

scientific article

N-Acylsulfonamide Linker Activation by Pd-Catalyzed Allylation

scientific article

Nanoscience and Nanotechnology Cross Borders.

scientific article published on 15 February 2017

Neoglycopolymer inhibitors of the selectins

Neoglycopolymers produced by aqueous ring-opening metathesis polymerization: decreasing saccharide density increases activity

New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography

scientific article

Non-carbohydrate inhibitors of the lectin DC-SIGN.

scientific article published on 29 September 2007

Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists

scientific article

Parallel synthesis of glycomimetic libraries: targeting a C-type lectin

scientific article

Peptide ligands that use a novel binding site to target both TGF-β receptors.

scientific article

Phage display affords peptides that modulate beta-amyloid aggregation

scientific article

Polymers at the Interface with Biology

scientific article published on 01 August 2018

Polysaccharide length affects mycobacterial cell shape and antibiotic susceptibility

scientific article published on 16 September 2020

Polyspecific pyrrolysyl-tRNA synthetases from directed evolution

scientific article

Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite.

scientific article published on January 2009

Probing and Perturbing Stem Cells with Chemical Biology

scientific article published on 01 January 2014

Protein footprinting in a complex milieu: identifying the interaction surfaces of the chemotaxis adaptor protein CheW

scientific article published on 02 April 2011

Quinoxalinone Inhibitors of the Lectin DC-SIGN.

scientific article

ROMP from ROMP: A New Approach to Graft Copolymer Synthesis

scientific article published on June 2009

Recasting Biomolecules for Function ⬇️

scientific article published on January 20, 2012

Recognition of microbial glycans by human intelectin-1

scientific journal article

Recognition of microbial glycans by soluble human lectins.

scientific article published on 5 May 2017

Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity.

scientific article published in March 1999

Rhamnose glycoconjugates for the recruitment of endogenous anti-carbohydrate antibodies to tumor cells

scientific article

Selective immobilization of multivalent ligands for surface plasmon resonance and fluorescence microscopy

scientific article

Selective tumor cell targeting using low-affinity, multivalent interactions

scientific article published on 26 February 2007

Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation.

scholarly article

Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins.

scientific article

Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues

scientific article published on 19 May 2007

Small-molecule-modified surfaces engage cells through the αvβ3 integrin.

scientific article

Solid-phase synthesis of alkanethiols for the preparation of self-assembled monolayers

scientific article

Solid-phase synthesis of polymers using the ring-opening metathesis polymerization.

scientific article published in October 2005

Spatial control of cell fate using synthetic surfaces to potentiate TGF-beta signaling

scientific article

Spotlight: A Conversation with Laura Kiessling and Jennifer Doudna

scientific article published in February 2018

Stereoelectronic Effects Impact Glycan Recognition

scientific article published on 24 January 2020

Stereoelectronic Effects Impact Glycan Recognition

Stereoselective N-Glycosylation by Staudinger Ligation

scientific article published in 2004

Stereoselective N-Glycosylation by Staudinger Ligation

Strength in numbers: non-natural polyvalent carbohydrate derivatives

scientific article published on 01 February 1996

Structure-based design of a periplasmic binding protein antagonist that prevents domain closure

scientific article

Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition

scientific article

Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification.

scientific article

Surface plasmon resonance imaging studies of protein-carbohydrate interactions

scientific article

Symbiosis: Chemical biology at Wisconsin.

scientific article published in September 2006

Syntheses and Applications of Bioactive Polymers Generated by Ring-Opening Metathesis Polymerization

Synthesis and applications of end-labeled neoglycopolymers

scientific article published in July 2002

Synthesis of Cell Agglutination Inhibitors by Aqueous Ring-Opening Metathesis Polymerization

scientific article published in 1994

Synthesis of a multivalent display of a CD22-binding trisaccharide

scientific article

Synthesis of end-labeled multivalent ligands for exploring cell-surface-receptor-ligand interactions.

scientific article

Synthesis of fluorogenic polymers for visualizing cellular internalization

scientific article published on 19 June 2008

Synthesis of functionalizable and degradable polymers by ring-opening metathesis polymerization

scientific article published on 8 April 2013

Synthesis of galactofuranose-based acceptor substrates for the study of the carbohydrate polymerase GlfT2.

scientific article

Synthesis of lipid-linked arabinofuranose donors for glycosyltransferases

scientific article published on 7 February 2013

Synthetic Multivalent Carbohydrate Ligands as Effectors or Inhibitors of Biological Processes

Synthetic Multivalent Ligands as Probes of Signal Transduction

Synthetic antigens reveal dynamics of BCR endocytosis during inhibitory signaling

scientific article

Synthetic glycoprotein mimics inhibit L-selectin-mediated rolling and promote L-selectin shedding

scientific article published on May 2004

Synthetic ligands point to cell surface strategies ⬇️

scientific article published on 01 March 1998

Synthetic multivalent ligands as probes of signal transduction

scientific article

Synthetische multivalente Liganden als Sonden für die Signaltransduktion

Tailored Synthetic Surfaces to Control Human Pluripotent Stem Cell Self-Renewal

Taxation on Innovation.

scientific article

The Ecstasy and Agony of Assay Interference Compounds

The Ecstasy and Agony of Assay Interference Compounds

The Ecstasy and Agony of Assay Interference Compounds

scientific article published on 28 February 2017

The Ecstasy and Agony of Assay Interference Compounds

The Ecstasy and Agony of Assay Interference Compounds

scientific article published in 2017

The Ecstasy and Agony of Assay Interference Compounds

The Ecstasy and Agony of Assay Interference Compounds

scientific article

The Ecstasy and Agony of Assay Interference Compounds.

scientific article published on 28 February 2017

The non-detergent sulfobetaine-201 acts as a pharmacological chaperone to promote folding and crystallization of the type II TGF-β receptor extracellular domain

scientific article

Training the next generation of biomedical investigators in glycosciences

scientific article published on February 2016

Transforming the cell surface through proteolysis ⬇️

scientific article published on March 1, 1998

Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface

scientific article

UDP-galactopyranose mutase in nematodes

scientific article published on 11 June 2013

Unexpected enhancement in biological activity of a GPCR ligand induced by an oligoethylene glycol substituent

scientific article published on July 2010

Update to Our Reader, Reviewer, and Author Communities-April 2020

scientific article published on 22 April 2020

Update to Our Reader, Reviewer, and Author Communities-April 2020

scientific article published on 23 April 2020

Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents

scientific article (publication date: 16 October 2015)

Visualization and characterization of receptor clusters by transmission electron microscopy

scientific article published in January 2003

Visualization of Single Multivalent Receptor-Ligand Complexes by Transmission Electron Microscopy The authors thank Colleen Lavin (UW Madison, Microscopy Resource) and Kim Dickson for experimental support. This work was supported in part by the NIH

scientific article published on 01 December 2000

Visualization of Single Multivalent Receptor–Ligand Complexes by Transmission Electron Microscopy

Visualization of Single Multivalent Receptor–Ligand Complexes by Transmission Electron Microscopy

scholarly article by Jason E. Gestwicki et al published 15 December 2000 in Angewandte Chemie

Visualization of Single Multivalent Receptor–Ligand Complexes by Transmission Electron Microscopy

article published in 2000

Voices in methods development

scientific article published on 01 October 2019

When the Others Become Us: A Chemist's Perspective of the COVID-19 Outbreak in Italy

scientific article published on 08 May 2020

X-ray crystallography reveals a reduced substrate complex of UDP-galactopyranose mutase poised for covalent catalysis by flavin

scientific article

p-Methoxybenzyl ether cleavage by polymer-supported sulfonamides

scientific article published on 01 April 2002

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