List of works - Sharmistha Sinha

A key role for lysine residues in amyloid β-protein folding, assembly, and toxicity.

scientific article published on 16 March 2012

A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo.

scientific article

Alanine Scanning Mutagenesis Identifies an Asparagine–Arginine–Lysine Triad Essential to Assembly of the Shell of the Pdu Microcompartment

scientific article

Analysis of the peanut agglutinin molten globule-like intermediate by limited proteolysis.

scientific article

Attributes of glycosylation in the establishment of the unfolding pathway of soybean agglutinin.

scientific article

Cellulose-metallothionein matrix for metal binding.

scientific article published on 17 March 2018

Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01

scientific article

Concurrence of Danish dementia and cataract: insights from the interactions of dementia associated peptides with eye lens alpha-crystallin

scientific article

Conformational stability and thermodynamic characterization of homotetrameric Plasmodium falciparum beta-ketoacyl-ACP reductase

scientific article published on 01 July 2007

Design of mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and new structural templates

scientific article

Diverse bacterial microcompartment organelles

scientific article

Functional protein shells fabricated from the self-assembling protein sheets of prokaryotic organelles

scientific article published on 01 January 2020

Genetic analysis of the protein shell of the microcompartments involved in coenzyme B12-dependent 1,2-propanediol degradation by Salmonella.

scientific article

Insights into hydrophobicity and the chaperone-like function of alphaA- and alphaB-crystallins: an isothermal titration calorimetric study.

scientific article published on 6 April 2005

Interactions between the termini of lumen enzymes and shell proteins mediate enzyme encapsulation into bacterial microcompartments.

scientific article

Interactions of aromatic mannosyl disulfide derivatives with concanavalin A: synthesis, thermodynamic and NMR spectroscopy studies.

scientific article published on 6 June 2009

Isothermal titration calorimetric study defines the substrate binding residues of calreticulin.

scientific article

Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein. Role of the 4'-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein

scientific article published on 06 June 2007

Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins

scientific article (publication date: 26 October 2011)

Napin from Brassica juncea: thermodynamic and structural analysis of stability

scientific article published on 01 May 2007

Probing into the role of conserved N-glycosylation sites in the Tyrosinase glycoprotein family.

scientific article

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

article

SPR and ITC determination of the kinetics and the thermodynamics of bivalent versus monovalent sugar ligand-lectin interactions

scientific article published on 23 October 2007

Selective molecular transport through the protein shell of a bacterial microcompartment organelle

scientific article

Subunit assembly of plant lectins.

scientific article published on 20 August 2007

Sugar-quantum dot conjugates for a selective and sensitive detection of lectins

scientific article published in January 2007

The PduM Protein Is a Structural Component of the Microcompartments Involved in Coenzyme B12-Dependent 1,2-Propanediol Degradation by Salmonella enterica ⬇️

scientific article published on February 17, 2012

The PduQ Enzyme Is an Alcohol Dehydrogenase Used to Recycle NAD+ Internally within the Pdu Microcompartment of Salmonella enterica ⬇️

scientific article published on October 15, 2012

Thermodynamic analysis of three state denaturation of Peanut Agglutinin.

scientific article published in September 2006

Unfolding energetics and stability of banana lectin.

scientific article

Variable Mutations at the p53-R273 Oncogenic Hotspot Position Leads to Altered Properties

scientific article published on 21 December 2019

List of works by Sharmistha Sinha

A key role for lysine residues in amyloid β-protein folding, assembly, and toxicity.

A novel "molecular tweezer" inhibitor of α-synuclein neurotoxicity in vitro and in vivo.

Alanine Scanning Mutagenesis Identifies an Asparagine–Arginine–Lysine Triad Essential to Assembly of the Shell of the Pdu Microcompartment

Analysis of the peanut agglutinin molten globule-like intermediate by limited proteolysis.

Attributes of glycosylation in the establishment of the unfolding pathway of soybean agglutinin.

Cellulose-metallothionein matrix for metal binding.

Comparison of three amyloid assembly inhibitors: the sugar scyllo-inositol, the polyphenol epigallocatechin gallate, and the molecular tweezer CLR01

Concurrence of Danish dementia and cataract: insights from the interactions of dementia associated peptides with eye lens alpha-crystallin

Conformational stability and thermodynamic characterization of homotetrameric Plasmodium falciparum beta-ketoacyl-ACP reductase

Design of mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and new structural templates

Diverse bacterial microcompartment organelles

Functional protein shells fabricated from the self-assembling protein sheets of prokaryotic organelles

Genetic analysis of the protein shell of the microcompartments involved in coenzyme B12-dependent 1,2-propanediol degradation by Salmonella.

Insights into hydrophobicity and the chaperone-like function of alphaA- and alphaB-crystallins: an isothermal titration calorimetric study.

Interactions between the termini of lumen enzymes and shell proteins mediate enzyme encapsulation into bacterial microcompartments.

Interactions of aromatic mannosyl disulfide derivatives with concanavalin A: synthesis, thermodynamic and NMR spectroscopy studies.

Isothermal titration calorimetric study defines the substrate binding residues of calreticulin.

Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein. Role of the 4'-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein

Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins

Napin from Brassica juncea: thermodynamic and structural analysis of stability

Probing into the role of conserved N-glycosylation sites in the Tyrosinase glycoprotein family.

Rational Design of β-Sheet Ligands Against Aβ42-Induced Toxicity

SPR and ITC determination of the kinetics and the thermodynamics of bivalent versus monovalent sugar ligand-lectin interactions

Selective molecular transport through the protein shell of a bacterial microcompartment organelle

Subunit assembly of plant lectins.

Sugar-quantum dot conjugates for a selective and sensitive detection of lectins

The PduM Protein Is a Structural Component of the Microcompartments Involved in Coenzyme B12-Dependent 1,2-Propanediol Degradation by Salmonella enterica ⬇️

The PduQ Enzyme Is an Alcohol Dehydrogenase Used to Recycle NAD+ Internally within the Pdu Microcompartment of Salmonella enterica ⬇️

Thermodynamic analysis of three state denaturation of Peanut Agglutinin.

Unfolding energetics and stability of banana lectin.

Variable Mutations at the p53-R273 Oncogenic Hotspot Position Leads to Altered Properties