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List of works by Simone P Niclou

<scp>AllergoOncology</scp>: Biomarkers and refined classification for research in the allergy and glioma nexus—A joint <scp>EAACI‐EANO</scp> position paper

scientific article published in 2024

A DNA Repair and Cell-Cycle Gene Expression Signature in Primary and Recurrent Glioblastoma: Prognostic Value and Clinical Implications

scientific article published on 23 January 2019

A novel eGFP-expressing immunodeficient mouse model to study tumor-host interactions.

scientific article published on 21 May 2008

A novel multilayer immunoisolating encapsulation system overcoming protrusion of cells.

scientific article

A novel role for Sema3A in neuroprotection from injury mediated by activated microglia.

scientific article published on February 2006

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

scientific article

AI-10DISTINCT EGFR SIGNALING IN GLIOBLASTOMA: WILD-TYPE EGFR PROMOTES INVASION WHILE EGFRvIII DRIVES PROTOTYPICAL SFK c-SRC ACTIVATION TO FOSTER ANGIOGENESIS.

scientific article published in November 2014

AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion

scientific article published on 11 December 2020

ATPS-59IMPROVING EFFICACY OF BEVACIZUMAB TREATMENT IN GLIOBLASTOMA BY TARGETING HIF1 ALPHA.

scientific article

Abstracts from the Third Quadrennial Meeting of the World Federation of Neuro-Oncology (WFNO) and the Sixth Meeting of the Asian Society for Neuro-Oncology (ASNO)

article

Altered metabolic landscape in IDH-mutant gliomas affects phospholipid, energy, and oxidative stress pathways.

scientific article published on 20 October 2017

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

scientific article

Anti-VEGF therapies for malignant glioma: treatment effects and escape mechanisms

scientific article published on 01 April 2009

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

scientific article

Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood-Brain Barrier

scientific article

Axitinib increases the infiltration of immune cells and reduces the suppressive capacity of monocytic MDSCs in an intracranial mouse melanoma model.

scientific article published on 22 January 2015

Bevacizumab treatment for human glioblastoma. Can it induce cognitive impairment?

scientific article published on May 2014

Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas

scientific article

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

scientific article published on 21 June 2017

Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system

scientific article

Changes in the expression of protease‐activated receptor 1 and protease nexin‐1 mRNA during rat nervous system development and after nerve lesion ⬇️

scientific article published on May 1, 1998

Ciliary neurotrophic factor cell-based delivery prevents synaptic impairment and improves memory in mouse models of Alzheimer's disease.

scientific article published in June 2010

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture

scientific article

Combined VEGFR and CTLA-4 blockade increases the antigen-presenting function of intratumoral DCs and reduces the suppressive capacity of intratumoral MDSCs

scientific article

Combined effect of tissue stabilization and protein extraction methods on phosphoprotein analysis.

scientific article published on 29 May 2013

Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma

scientific article

Correction: A Novel, Diffusely Infiltrative Xenograft Model of Human Anaplastic Oligodendroglioma with Mutations in FUBP1, CIC, and IDH1.

scientific article published on 6 August 2013

DNA repair mechanisms and their clinical impact in glioblastoma

scientific article

Databases for lncRNAs: a comparative evaluation of emerging tools

scientific article

Drug and cell encapsulation: alternative delivery options for the treatment of malignant brain tumors.

scientific article published on 31 January 2014

Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia

scientific article published on 13 February 2018

Dual blockade of STAT3 and EGFR, a key to unlock drug resistance in Glioblastoma?

scientific article published on 14 February 2020

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors

scientific article published on 01 September 2018

EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis

scientific article published on 22 February 2013

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

scientific article published on 10 June 2016

Efficient delivery of Cre-recombinase to neurons in vivo and stable transduction of neurons using adeno-associated and lentiviral vectors

scientific article

Expression of the thrombin receptor mRNA in rat brain.

scientific article published in May 1994

Factors influencing the mechanical stability of alginate beads applicable for immunoisolation of mammalian cells.

scientific article

Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity

scientific article published on 19 February 2020

Gauging heterogeneity in primary versus recurrent glioblastoma.

scientific article

Gene set based integrated data analysis reveals phenotypic differences in a brain cancer model

scientific article

Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes.

scientific article published on 24 October 2013

Glioma Through the Looking GLASS: Molecular Evolution of Diffuse Gliomas and the Glioma Longitudinal AnalySiS Consortium.

scientific article published on 8 February 2018

Glioma proteomics: status and perspectives.

scientific article published on 20 March 2010

Glutamate as chemotactic fuel for diffuse glioma cells: are they glutamate suckers?

scientific article

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.

scientific article

Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

scientific article

Harnessing LRIG1-mediated inhibition of receptor tyrosine kinases for cancer therapy

scientific article published on March 2017

IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA.

scientific article published in July 2014

In vivo models of primary brain tumors: pitfalls and perspectives ⬇️

scientific article published on June 7, 2012

Increased formate overflow is a hallmark of oxidative cancer.

scientific article

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

scientific article published on 29 May 2013

Intercellular transfer of transferrin receptor by a contact-, Rab8-dependent mechanism involving tunneling nanotubes.

scientific article published on 28 July 2015

Intravitreal injection of adeno-associated viral vectors results in the transduction of different types of retinal neurons in neonatal and adult rats: a comparison with lentiviral vectors.

scientific article published in September 2002

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma

scientific article published in January 2017

Lentiviral-mediated transfer of CNTF to schwann cells within reconstructed peripheral nerve grafts enhances adult retinal ganglion cell survival and axonal regeneration.

scientific article published in June 2005

MAPPING THE GLIOBLASTOMA METABOLOME AFTER BEVACIZUMAB THERAPY BY 13C6-GLUCOSE METABOLOMIC FLUX ANALYSIS.

scientific article published in July 2014

METB-09IDENTIFYING NOVEL VULNERABILITIES IN OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT GLIOMA.

scientific article

Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma

scientific article published on 25 March 2016

Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies.

scientific article

Novel ways to target brain tumour metabolism.

scientific article published on 02 June 2011

O1.05AXITINIB, A SELECTIVE VEGFR-1,-2,-3 TYROSINE KINASE INHIBITOR, INHIBITS TUMOR GROWTH AND INCREASES INFILTRATION OF IMMUNE CELLS IN AN INTRACRANIAL MELANOMA MOUSE MODEL.

scientific article published in September 2014

O10.03PHYSIOLOGICAL AND BIOLOGICAL RESPONSES OF HUMAN GLIOBLASTOMAS TO BEVACIZUMAB TREATMENT ASSESSED BY METABOLOMIC FLUX ANALYSIS.

scientific article published in September 2014

O4.09IN SITU METABOLIC PROFILING SHEDS LIGHT ON OXIDATIVE STRESS PATHWAYS IN IDH1 MUTANT OLIGODENDROGLIOMA.

scientific article published in September 2014

OS1.2 Effects of the IDH1R132H mutation on redox-status and metabolism are cell type dependent but independent from D-2-hydroxyglutarate accumulation.

scientific article published on 21 September 2016

OS1.7 Regulatory RNAs, a missing link in Glioblastoma response to Temozolomide? ⬇️

scientific article

Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry

scientific article published on 22 June 2021

P01.07 Identification of novel molecular targets for TMZ-based therapies against glioblastoma: A comprehensive shRNA-based screen of DNA Damage Response factors.

scientific article

P01.08 Targeting DNA repair mechanisms in glioblastoma: from basic mechanisms to pre-clinical aspects and personalized therapy.

scientific article published on 21 September 2016

P04.01 Characterization of microglia/macrophage phenotypes in glioma patient-derived xenograft mouse models.

scientific article published on 21 September 2016

P05.01 Patient-derived xenograft (PDX) model of glioblastoma: from basic research to preclinical studies.

scientific article published on 21 September 2016

P08.24 Characterization of glioma cell invasion: towards novel therapeutic targets.

scientific article

P08.57 Distinct mechanism-of-action of dianhydrogalactitol (VAL-083) overcomes chemoresistance in glioblastoma.

scientific article

P16.24MULTIMODAL IMAGING ELUCIDATES PHYSIOLOGICAL AND METABOLIC CHANGES INDUCED BY ANTI-ANGIOGENIC THERAPY IN GLIOBLASTOMA.

scientific article

P17.29IDENTIFICATION OF NOVEL MOLECULAR TARGETS FOR TEMOZOLOMIDE-BASED THERAPIES AGAINST GLIOBLASTOMA: A COMPREHENSIVE SHRNA-BASED SCREEN OF DNA REPAIR FACTORS.

scientific article published in September 2014

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology

scientific article published on 03 October 2020

PeptideManager: a peptide selection tool for targeted proteomic studies involving mixed samples from different species

scientific article

Proteomics strategies for target identification and biomarker discovery in cancer.

scientific article published on January 2009

Prothrombin overexpressed in post-natal neurones requires blood factors for activation in the mouse brain.

scientific article published in March 2004

RNAi/CRISPR Screens: from a Pool to a Valid Hit

scientific article published on 31 August 2018

Regulation of hypoxia-induced autophagy in glioblastoma involves ATG9A.

scientific article published on 10 August 2017

Revival of the VEGF ligand family?

scientific article published on 01 October 2018

Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures

scientific article published on 11 September 2018

Slit2 is a repellent for retinal ganglion cell axons

scientific article

Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment

scientific article published on 16 April 2019

TM-14 * THE ANGIOGENIC SWITCH LEADS TO A METABOLIC SWITCH IN HUMAN GLIOBLASTOMA

Targeted Proteomics to Assess the Response to Anti-Angiogenic Treatment in Human Glioblastoma (GBM).

scientific article published on 4 August 2015

Temozolomide-Induced RNA Interactome Uncovers Novel LncRNA Regulatory Loops in Glioblastoma

scientific article published on 10 September 2020

The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment

scientific article published on 18 June 2019

The angiogenic switch leads to a metabolic shift in human glioblastoma

scientific article published on 3 September 2016

The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways.

scientific article

The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease

scientific article (publication date: 2006)

The serine protease granzyme A does not induce platelet aggregation but inhibits responses triggered by thrombin.

scientific article published on May 1996

The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein-protein interaction in glioblastoma

scientific article published on 01 May 2019

The soluble form of the tumor suppressor Lrig1 potently inhibits in vivo glioma growth irrespective of EGF receptor status.

scientific article published on 30 May 2013

The thrombin receptor in the nervous system.

scientific article published on January 1996

The thrombin receptor is present in myoblasts and its expression is repressed upon fusion

scientific article published on 01 November 1996

Therapeutic control and resistance of the EGFR-driven signaling network in glioblastoma

scientific article

Tumor versus stromal cells in culture--survival of the fittest?

scientific article

U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells

scientific article

Viral vector-mediated gene expression in olfactory ensheathing glia implants in the lesioned rat spinal cord.

scientific article

Whole genomes redefine the mutational landscape of pancreatic cancer

scientific article published in February 2015

iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype

scientific article published on 12 August 2009

αB-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells ⬇️

scientific article published on September 2, 2010

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