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List of works by Elin Nyman

A hierarchical whole-body modeling approach elucidates the link between in Vitro insulin signaling and in Vivo glucose homeostasis.

scientific article

A single mechanism can explain network-wide insulin resistance in adipocytes from obese patients with type 2 diabetes.

scientific article

A systems biology analysis connects insulin receptor signaling with glucose transporter translocation in rat adipocytes

scientific article published on 11 May 2017

A systems biology analysis of adrenergically stimulated adiponectin exocytosis in white adipocytes

scientific article published on 29 September 2021

Cross-talks via mTORC2 can explain enhanced activation in response to insulin in diabetic patients.

scientific article published on 16 December 2016

Effects of IL-1β-Blocking Therapies in Type 2 Diabetes Mellitus: A Quantitative Systems Pharmacology Modeling Approach to Explore Underlying Mechanisms

scientific article published on 11 June 2014

Insulin signaling - mathematical modeling comes of age.

scientific article published on 28 January 2012

Insulin signaling in type 2 diabetes: experimental and modeling analyses reveal mechanisms of insulin resistance in human adipocytes.

scientific article published on 11 February 2013

LASSIM-A network inference toolbox for genome-wide mechanistic modeling

scientific article

Mathematical modeling improves EC50 estimations from classical dose-response curves.

scientific article published on 6 February 2015

Mathematical modeling of white adipocyte exocytosis predicts adiponectin secretion and quantifies the rates of vesicle exo- and endocytosis.

scientific article

Mechanistic explanations for counter-intuitive phosphorylation dynamics of the insulin receptor and insulin receptor substrate-1 in response to insulin in murine adipocytes.

scientific article published on 15 February 2012

Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State.

scientific article published on 10 September 2015

Perturbation biology links temporal protein changes to drug responses in a melanoma cell line

scientific article published on 15 July 2020

Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes

scientific article published on April 2016

Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes

scientific article published on 3 October 2017

Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes

scientific article published on 20 May 2016

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