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List of works by Roberto Bolli

"String theory" of c-kit(pos) cardiac cells: a new paradigm regarding the nature of these cells that may reconcile apparently discrepant results

scientific article

A Call to Make the Human Dimension of Science a Core Component of Scientific Journals

scientific article published on 01 March 2018

A New Method to Stabilize C-Kit Expression in Reparative Cardiac Mesenchymal Cells

scientific article

A New Standard in the Conflict of Interest Policy of the American Heart Association ⬇️

scientific article published on September 2, 2011

A highly sensitive and accurate method to quantify absolute numbers of c-kit+ cardiac stem cells following transplantation in mice

scientific article published on 03 April 2013

A murine model of inducible, cardiac-specific deletion of STAT3: Its use to determine the role of STAT3 in the upregulation of cardioprotective proteins by ischemic preconditioning

article

A realistic appraisal of the use of embryonic stem cell-based therapies for cardiac repair

scientific article published on 28 November 2019

Acrolein consumption exacerbates myocardial ischemic injury and blocks nitric oxide-induced PKCepsilon signaling and cardioprotection

scientific article published on 8 April 2008

Actions speak much louder than words: for midcareer and senior investigators, the track record of productivity should be paramount in selecting grant recipients

scientific article

Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan

scientific journal article

Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivo

scientific article published on 2 January 2004

Administration of a CO-releasing molecule induces late preconditioning against myocardial infarction

scientific article

Administration of cardiac mesenchymal cells modulates innate immunity in the acute phase of myocardial infarction in mice

scientific article published on 08 September 2020

Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance

scientific article

Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis

scientific article

Adult bone marrow-derived cells: regenerative potential, plasticity, and tissue commitment

scientific article published in November 2005

After the Storm: An Objective Appraisal of the Efficacy of c-kit+ Cardiac Progenitor Cells in Preclinical Models of Heart Disease

scientific article published on 16 September 2020

Aldose reductase is an obligatory mediator of the late phase of ischemic preconditioning

scientific article published in August 2002

Allogeneic Mesenchymal Cell Therapy in Anthracycline-Induced Cardiomyopathy Heart Failure Patients: The CCTRN SENECA Trial

scientific article published on 01 November 2020

Announcing "New Leaders in Cardiovascular Science".

scientific article published on 26 September 2013

Announcing the "Meet the First Author" Page

scientific article published in February 2017

Another addition to our article portfolio: announcing Brief UltraRapid Communications

scientific article published on 01 April 2010

Atorvastatin Therapy during the Peri-Infarct Period Attenuates Left Ventricular Dysfunction and Remodeling after Myocardial Infarction ⬇️

scientific article published on September 28, 2011

Author Correction: Circulating Biomarkers to Identify Responders in Cardiac Cell therapy.

scientific article published on 6 March 2018

Bmx, a member of the Tec family of nonreceptor tyrosine kinases, is a novel participant in pharmacological cardioprotection

scientific article

Bone marrow cell characteristics associated with patient profile and cardiac performance outcomes in the LateTIME-Cardiovascular Cell Therapy Research Network (CCTRN) trial

scientific article

Bone marrow cell-mediated cardiac regeneration a veritable revolution

scientific article published on 01 November 2005

Bone marrow cells adopt the cardiomyogenic fate in vivo

scientific article

Bone marrow cells for cardiac regeneration: the quest for the protagonist continues.

scientific article

Bone marrow for cardiac repair: the importance of characterizing the phenotype and function of injected cells

scientific article published on 5 March 2007

Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network

scientific article

Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction

scientific article published on 04 March 2008

C-Kit Promotes Growth and Migration of Human Cardiac Progenitor Cells via the PI3K-AKT and MEK-ERK Pathways

scientific article published on 16 October 2015

COX-2-derived prostacyclin mediates opioid-induced late phase of preconditioning in isolated rat hearts

scientific article published on 8 August 2002

CRYAB and HSPB2 deficiency alters cardiac metabolism and paradoxically confers protection against myocardial ischemia in aging mice

scientific article published on 14 September 2007

Carbon monoxide induces a late preconditioning-mimetic cardioprotective and antiapoptotic milieu in the myocardium

scientific article published on 19 November 2011

Cardiac Stem Cells in Patients with Ischemic Cardiomyopathy: Discovery, Translation, and Clinical Investigation ⬇️

scientific article published on October 1, 2012

Cardiac mesenchymal cells from diabetic mice are ineffective for cell therapy-mediated myocardial repair

article

Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition

scientific article published on 20 October 2008

Cardiac preconditioning during percutaneous coronary interventions

scientific article

Cardiac progenitor cells and bone marrow-derived very small embryonic-like stem cells for cardiac repair after myocardial infarction

scientific article

Cardiac progenitor cells: the revolution continues

scientific article published in November 2005

Cardiac stem cell therapy for cardiac repair

scientific article

Cardiac stem cells and myocardial disease

scientific article published on 13 June 2008

Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function

scientific article

Cardiac stem cells in patients with ischaemic cardiomyopathy - Authors' reply

scientific article published on 08 March 2012

Cardiomyocyte Regeneration: A Consensus Statement

scientific article published on 6 July 2017

Cardiomyocyte-restricted overexpression of extracellular superoxide dismutase increases nitric oxide bioavailability and reduces infarct size after ischemia/reperfusion ⬇️

scientific article published on October 26, 2012

Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathway

scientific article published on 4 September 2007

Cardioprotection by postconditioning in conscious rats is limited to coronary occlusions <45 min.

scientific article published on 30 June 2006

Cardioprotection during the final stage of the late phase of ischemic preconditioning is mediated by neuronal NO synthase in concert with cyclooxygenase-2.

scientific article

Cardioprotection involves activation of NF-kappa B via PKC-dependent tyrosine and serine phosphorylation of I kappa B-alpha

scientific article

Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart

scientific article

Cardioprotective effects of short-term caloric restriction are mediated by adiponectin via activation of AMP-activated protein kinase

scientific article published on 26 November 2007

Cause of death: suicide

scientific article

Cell Therapy Needs Rigorous Translational Studies in Large Animal Models

scientific article published in November 2015

Cell therapy for acute myocardial infarction: Requiescat in Pace

scientific article published on 01 October 2020

Cell therapy for heart disease: current status and future directions

scientific article published on 10 January 2018

Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions

scientific article

Cells expressing early cardiac markers reside in the bone marrow and are mobilized into the peripheral blood after myocardial infarction

scientific article published on 18 November 2004

Chronic AMD3100 antagonism of SDF-1alpha-CXCR4 exacerbates cardiac dysfunction and remodeling after myocardial infarction

scientific article published on 23 July 2010

Circulating Biomarkers to Identify Responders in Cardiac Cell therapy

scientific article published on 30 June 2017

Circulation Research 2017 Best Manuscript Award Winners

scientific article

Circulation Research Editors’ Annual Report for 2004

Circulation Research Editors’ Yearly Report: 2003

Circulation Research and human genetic studies

scientific article published on July 2010

Circulation Research launches a clinical track for studies in humans

scientific article

Clinical Studies of Cell Therapy in Cardiovascular Medicine: Recent Developments and Future Directions

scientific article published on 01 July 2018

Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts

scientific article

Commentaries—Another Addition to the Portfolio of Circulation Research ⬇️

scientific article published on January 21, 2011

Comparison of One and Three Intraventricular Injections of Cardiac Progenitor Cells in a Murine Model of Chronic Ischemic Cardiomyopathy

scientific article published on 28 October 2020

Comparison of coliform contamination in non-municipal waters consumed by the Mennonite versus the non-Mennonite rural populations

scientific article

Concise Review: Review and Perspective of Cell Dosage and Routes of Administration From Preclinical and Clinical Studies of Stem Cell Therapy for Heart Disease

scientific article

Concise review: stem cells, myocardial regeneration, and methodological artifacts

scientific article published on 22 November 2006

Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure

scientific article published on 01 January 2019

Correction: Human Cardiac Stem Cells Isolated from Atrial Appendages Stably Express c-kit

Correction: Human Cardiac Stem Cells Isolated from Atrial Appendages Stably Express c-kit.

scientific article published on 19 January 2012

Correction: Human Cardiac Stem Cells Isolated from Atrial Appendages Stably Express c-kit.

scientific article

Correction: The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-related kinase (ERK)/NRF2 signaling pathway and cytokine release

scientific article published in 2019

Current status of cell therapy for non-ischaemic cardiomyopathy: a brief overview

scientific article published on 10 September 2015

Dandum semper est tempus: The Crucial Importance of (and Increasing Disregard for) the Test of Time

scientific article published on 01 October 2015

Delayed adaptation of the heart to stress: late preconditioning

scientific article published on 30 September 2004

Delayed preconditioning-mimetic actions of nitroglycerin in patients undergoing exercise tolerance tests

scientific article published on 16 May 2005

Delta-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits

scientific article published in November 2002

Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes.

scientific article

Development of an NIH Consortium for PreclinicAl AssESsment of CARdioprotective Therapies (CAESAR): A Paradigm Shift in Studies of Infarct Size Limitation ⬇️

scientific article published on September 1, 2011

Discovery of a new function of cyclooxygenase (COX)-2: COX-2 is a cardioprotective protein that alleviates ischemia/reperfusion injury and mediates the late phase of preconditioning

scientific article (publication date: 15 August 2002)

Editor's Preamble to the Profile of Eric Olson

scientific article published in October 2015

Editor's Preamble to the Profile of Eugene Braunwald

scientific article published in October 2015

Editor's Preamble to the Profile of James Willerson

scientific article published in October 2015

Editor's Preamble to the Profile of Joseph Goldstein and Michael Brown

scientific article published in October 2015

Editor's Preamble to the Profile of Louis Ignarro

scientific article published in October 2015

Editor's Preamble to the Profile of Oliver Smithies

scientific article published in October 2015

Editor's Preamble to the Profile of Robert Jennings

scientific article published in October 2015

Editor's Preamble to the Profile of Robert Lefkowitz

scientific article published in October 2015

Effect of Molecular Weight on Sonoporation-Mediated Uptake in Human Cells

scientific article published on 29 September 2018

Effect of aspirin on late preconditioning against myocardial stunning in conscious rabbits

scientific article (publication date: 2 April 2003)

Effect of the stop-flow technique on cardiac retention of c-kit positive human cardiac stem cells after intracoronary infusion in a porcine model of chronic ischemic cardiomyopathy.

scientific article

Effects of Intracoronary Infusion of Escalating Doses of Cardiac Stem Cells in Rats With Acute Myocardial Infarction

scientific article published on 20 May 2015

Effects of anesthesia on echocardiographic assessment of left ventricular structure and function in rats

scientific article published on 2 October 2006

Endoplasmic reticulum stress-dependent activation of ATF3 mediates the late phase of ischemic preconditioning

scientific article

Endothelial nitric oxide synthase is not necessary for the early phase of ischemic preconditioning in the mouse

scientific article published on 17 January 2008

Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase C epsilon p44/42 mitogen-activated protein kinase pSer-signal transducers and activators of transcription1/3 pa

scientific article published on 2 July 2007

Endothelial progenitor cells: neovascularization or more?

scientific article published on 01 January 2006

Epigenetically modified cardiac mesenchymal stromal cells limit myocardial fibrosis and promote functional recovery in a model of chronic ischemic cardiomyopathy

scientific article published on 16 November 2018

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells).

scientific article published on 16 February 2017

Expression of activated PKC epsilon (PKC epsilon) protects the ischemic heart, without attenuating ischemic H(+) production

scientific article

Fms-related tyrosine kinase 3 expression discriminates hematopoietic stem cells subpopulations with differing engraftment-potential: identifying the most potent combination

scientific article published in April 2008

Foreword--focused issue on cardiac repair by stem cells

scientific article published on 01 November 2005

Formation of large coronary arteries by cardiac progenitor cells

scholarly article

Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection

scientific article

Gender and aging do not impair opioid-induced late preconditioning in rats

scientific article

Gene Therapy With Inducible Nitric Oxide Synthase Protects Against Myocardial Infarction via a Cyclooxygenase-2–Dependent Mechanism ⬇️

scientific article published on April 18, 2003

Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptor

scientific article

Gene therapy with iNOS provides long-term protection against myocardial infarction without adverse functional consequences

scientific article published on 19 September 2005

Gene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequences ⬇️

scientific article published on July 21, 2011

Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences

scientific article published on 22 July 2011

Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathway

scientific article published on 14 September 2009

Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury.

scientific article published on 13 July 2015

Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of

scientific article published on 03 August 2012

Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine

scientific article published in January 2018

Global position paper on cardiovascular regenerative medicine

article

Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation

scientific article published on 26 May 2015

Granulocyte colony-stimulating factor therapy for cardiac repair after acute myocardial infarction: a systematic review and meta-analysis of randomized controlled trials

scientific article published on 20 June 2008

Guidelines for Experimental Models of Myocardial Ischemia and Infarction

scientific article published on 12 January 2018

HO-1 induction by HIF-1: a new mechanism for delayed cardioprotection?

scientific article published on 01 August 2005

Heart slice culture system reliably demonstrates clinical drug-related cardiotoxicity

scientific article published on 30 August 2020

Hematopoietic cytokines for cardiac repair: mobilization of bone marrow cells and beyond

scientific article published on 04 May 2011

Hepatocyte growth factor/Met gene transfer in cardiac stem cells--potential for cardiac repair

scientific article published on July 2010

Histone Deacetylase 1 Depletion Activates Human Cardiac Mesenchymal Stromal Cell Proangiogenic Paracrine Signaling Through a Mechanism Requiring Enhanced Basic Fibroblast Growth Factor Synthesis and Secretion

scientific article published on 5 July 2017

Human Embryonic Stem Cell-Derived Cardiomyocytes

scientific article published on 01 April 2019

Human cardiac stem cells

scholarly article

Human cardiac stem cells isolated from atrial appendages stably express c-kit

scientific article

Hypercholesterolemia abrogates late preconditioning via a tetrahydrobiopterin-dependent mechanism in conscious rabbits

scientific article published on 26 September 2005

Hypercholesterolemia blunts NO donor-induced late preconditioning against myocardial infarction in conscious rabbits

scientific article published on 16 September 2004

IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2.

scientific article published on October 2004

Identification of Bone Marrow Cell Subpopulations Associated With Improved Functional Outcomes in Patients With Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial

scientific article

Identification of cardiovascular risk factors associated with bone marrow cell subsets in patients with STEMI: a biorepository evaluation from the CCTRN TIME and LateTIME clinical trials

scientific article published on 23 November 2016

Identification of heme oxygenase 1 (HO-1) as a novel negative regulator of mobilization of hematopoietic stem/progenitor cells

scientific article published on February 2015

Identification of inducible nitric oxide synthase in peripheral blood cells as a mediator of myocardial ischemia/reperfusion injury ⬇️

scientific article published on February 21, 2012

Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1.

scientific article published on 17 October 2008

Impact of Cell Therapy on Myocardial Perfusion and Cardiovascular Outcomes in Patients With Angina Refractory to Medical Therapy: A Systematic Review and Meta-Analysis

scientific article

Impact of long-term Xuezhikang therapy on cardiovascular events in high-risk patients with nonspecific, preexisting abnormal liver tests: A post-hoc analysis from Chinese Coronary Secondary Prevention Study (CCSPS) ⬇️

scientific article published on 01 December 2011

Impact of sodium-hydrogen exchange inhibition by cariporide on death or myocardial infarction in high-risk CABG surgery patients: results of the CABG surgery cohort of the GUARDIAN study

scientific article published in August 2003

Increased Risk of Adverse Neurocognitive Outcomes With Proprotein Convertase Subtilisin-Kexin Type 9 Inhibitors

scientific article

Increasing evidence that estrogen is an important modulator of bone marrow-mediated cardiac repair after acute infarction

scientific article published on 01 November 2006

Inducible cardiac-specific overexpression of cyclooxygenase-2 (COX-2) confers resistance to ischemia/reperfusion injury

scientific article published on 05 July 2019

Inducible nitric oxide synthase modulates cyclooxygenase-2 activity in the heart of conscious rabbits during the late phase of ischemic preconditioning

scientific article published in March 2002

Inhibition of mammalian target of rapamycin protects against reperfusion injury in diabetic heart through STAT3 signaling

scientific article

Inotrope use at separation from cardiopulmonary bypass and the role of prebypass TEE

scientific article published on 01 August 2004

Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction

scientific article

Intracoronary administration of cardiac stem cells in mice: a new, improved technique for cell therapy in murine models ⬇️

scientific article published on April 24, 2011

Intracoronary delivery of autologous cardiac stem cells improves cardiac function in a porcine model of chronic ischemic cardiomyopathy

scientific article published on 11 June 2013

Introducing Yet Another Addition to Our Portfolio: Promising Young Investigators

scientific article published in November 2016

Introduction to Cardiovascular Aging Compendium

scientific article published on 01 September 2018

Introduction to a Compendium on Regenerative Cardiology

scientific article published on 01 July 2018

Ischemic preconditioning upregulates inducible nitric oxide synthase in cardiac myocyte

scientific article published on 01 January 2002

Late preconditioning induced by NO donors, adenosine A1 receptor agonists, and delta1-opioid receptor agonists is mediated by iNOS

scientific article

Life and death of cardiac stem cells: a paradigm shift in cardiac biology

scientific article

Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function

scientific article published on 12 June 2008

Long-Term Outcome of Administration of c-kit(POS) Cardiac Progenitor Cells After Acute Myocardial Infarction: Transplanted Cells Do not Become Cardiomyocytes, but Structural and Functional Improvement and Proliferation of Endogenous Cells Persist fo

scientific article published on 2 February 2016

Long-term engraftment and angiogenic properties of lentivirally transduced adipose tissue-derived stromal cells

scientific article

Loss of ischaemic preconditioning in ovariectomized rat hearts: possible involvement of impaired protein kinase C epsilon phosphorylation

scientific article published on 4 April 2008

MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning

scientific article published on March 2003

Mechanism of cyclooxygenase-2 upregulation in late preconditioning ⬇️

scientific article published on May 1, 2003

Meta-analysis of short- and long-term efficacy of mononuclear cell transplantation in patients with myocardial infarction

scientific article published on 11 November 2019

Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection

scientific article (publication date: 8 March 2002)

Molecular and Cellular Mechanisms Associated with Effects of Molecular Hydrogen in Cardiovascular and Central Nervous Systems

scientific article published on 15 December 2020

Molecular genetic advances in cardiovascular medicine: focus on the myocyte

scientific article published on June 2004

Myocardial Reparative Properties of Cardiac Mesenchymal Cells Isolated on the Basis of Adherence

scientific article published on April 2017

Myocardial aging--a stem cell problem

scientific article

Myocardial protection at a crossroads: the need for translation into clinical therapy

scientific article published in July 2004

Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure

scientific article

Neurocognitive Risk With PCSK9 Inhibitors: Need for More Robust Evidence

scientific article published on 01 May 2017

New Initiatives to Improve the Rigor and Reproducibility of Articles Published in Circulation Research

scientific article published in August 2017

New Paradigms in Cell Therapy: Repeated Dosing, Intravenous Delivery, Immunomodulatory Actions, and New Cell Types

New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop

scientific article published on September 2011

New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine

scientific article published on January 2004

Nicorandil induces late preconditioning against myocardial infarction in conscious rabbits

scientific article published on 18 December 2003

Nitric oxide (NO) induces nitration of protein kinase Cepsilon (PKCepsilon ), facilitating PKCepsilon translocation via enhanced PKCepsilon -RACK2 interactions: a novel mechanism of no-triggered activation of PKCepsilon

scientific article published on 11 February 2002

No pain, no gain: the useful function of angina

scientific article published in December 2005

Noncanonical Wnt11 signaling is sufficient to induce cardiomyogenic differentiation in unfractionated bone marrow mononuclear cells

scientific article published on 21 April 2008

Nonelectrocardiographic evidence that both ischemic preconditioning and adenosine preconditioning exist in humans

scientific article published in August 2003

Notch1 regulates the fate of cardiac progenitor cells

scientific article

O-GlcNAcylation Negatively Regulates Cardiomyogenic Fate in Adult Mouse Cardiac Mesenchymal Stromal Cells

scientific article published on 13 November 2015

Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering

scientific article published in August 2017

Overexpression of mitogen-activated protein kinase kinase 6 in the heart improves functional recovery from ischemia in vitro and protects against myocardial infarction in vivo

scientific article published on 18 October 2004

Oxidant species trigger late preconditioning against myocardial stunning in conscious rabbits ⬇️

scientific article published on January 1, 2002

Oxygen Administration Does Not Influence the Prognosis of Acute Myocardial Infarction: A Meta-Analysis

scientific article published on 2 November 2016

Paul Simpson and Scientific Rigor

scientific article published on 01 January 2019

Peripheral Blood Cytokine Levels After Acute Myocardial Infarction: IL-1β- and IL-6-Related Impairment of Bone Marrow Function

scientific article published on 10 May 2017

Perspectives on Directions and Priorities for Future Preclinical Studies in Regenerative Medicine

scientific article published on 01 March 2019

Phase II clinical research design in cardiology: learning the right lessons too well: observations and recommendations from the Cardiovascular Cell Therapy Research Network (CCTRN).

scientific article published on April 2013

Physiological Biomimetic Culture System for Pig and Human Heart Slices

scientific article published on 16 July 2019

Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function

scientific article published on 23 March 2006

Potential Strategies for Clinical Translation of Repeated Cell Therapy

scientific article published on 01 March 2019

Preamble to the Profile of Dr Abboud and Reflections on the Future of American Medical Education ⬇️

scientific article published on February 1, 2013

Preconditioning Human Cardiac Stem Cells with an HO-1 Inducer Exerts Beneficial Effects After Cell Transplantation in the Infarcted Murine Heart

scientific article published on 24 August 2015

Preconditioning: a paradigm shift in the biology of myocardial ischemia

scientific article published on 8 September 2006

Pretreatment with intracoronary enalaprilat protects human myocardium during percutaneous coronary angioplasty

scientific article published on 02 April 2007

Pro-Angiogenic Actions of CMC-Derived Extracellular Vesicles Rely on Selective Packaging of Angiopoietin 1 and 2, but Not FGF-2 and VEGF

scientific article published on 01 August 2019

Proapoptotic effects of caspase-1/interleukin-converting enzyme dominate in myocardial ischemia

scientific article

Prostacyclin attenuates oxidative damage of myocytes by opening mitochondrial ATP-sensitive K+ channels via the EP3 receptor

scientific article published on 16 December 2004

Protein O-GlcNAcylation is a novel cytoprotective signal in cardiac stem cells

scientific article

Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria

scientific article

Protein tyrosine kinase signaling is necessary for NO donor-induced late preconditioning against myocardial stunning

scientific article published on 12 December 2002

RETRACTED: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial

RETRACTED: scientific article (publication date: 26 November 2011)

Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit Cardiac Stem Cells As Regenerative Therapy for Heart Failure)

scientific article published on 27 April 2018

Rationale and Design of the SENECA (StEm cell iNjECtion in cAncer survivors) Trial

scientific article published on 04 April 2018

Reaching out to young investigators

scientific article published on 01 March 2014

Recognizing the Top Reviewers of 2017 for Circulation Research

scientific article published in February 2018

Reflections on the Irreproducibility of Scientific Papers

scientific article published on 01 September 2015

Regeneration of the Human Heart — No Chimera? ⬇️

scientific article published on 01 January 2002

Repeated Administrations of Cardiac Progenitor Cells Are Markedly More Effective Than a Single Administration: A New Paradigm in Cell Therapy

scientific article published on 30 June 2016

Repeated Administrations of Cardiac Progenitor Cells Are Superior to a Single Administration of an Equivalent Cumulative Dose

scientific article published on 13 February 2018

Repeated Cell Therapy: A Paradigm Shift Whose Time Has Come

scientific article published on 8 February 2017

Repeated doses of cardiac mesenchymal cells are therapeutically superior to a single dose in mice with old myocardial infarction

scientific article published on 16 February 2017

Response to letter regarding article, "Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions".

scientific article published in November 2014

Role of Src protein tyrosine kinases in late preconditioning against myocardial infarction

scientific article

Role of cyclic guanosine monophosphate in late preconditioning in conscious rabbits

scientific article published in June 2002

Role of nitric oxide in myocardial preconditioning

scientific article

Role of the JAK-STAT pathway in protection against myocardial ischemia/reperfusion injury

scientific article

Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning

scientific article published on 19 September 2005

STAT3 Signaling in B Cells Is Critical for Germinal Center Maintenance and Contributes to the Pathogenesis of Murine Models of Lupus

scientific article published on 25 April 2016

Safety of intracoronary infusion of 20 million C-kit positive human cardiac stem cells in pigs

scientific article published on 23 April 2015

Sca-1 expression is associated with decreased cardiomyogenic differentiation potential of skeletal muscle-derived adult primitive cells

scientific article published in October 2006

Short and long non-coding RNAs regulate the epigenetic status of cells

scientific article published on 28 August 2017

Short-term caloric restriction improves ischemic tolerance independent of opening of ATP-sensitive K+ channels in both young and aged hearts

scientific article published in August 2005

Slicing and Culturing Pig Hearts under Physiological Conditions

scientific article published on 20 March 2020

Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION study

scientific article published on April 2008

Statistical Methods for Selecting Maximum Effective Dose and Evaluating Treatment Effect When Dose - Response is Monotonic

scientific article

Stem cell niches in the adult mouse heart

scholarly article

Stem cell therapy: promising treatment in heart failure?

scientific article published on March 2013

Stem cells: Cell therapy for cardiac repair: what is needed to move forward?

scientific article published on 31 March 2017

Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis

scientific article published on 23 July 2007

TGF-beta1 enhances cardiomyogenic differentiation of skeletal muscle-derived adult primitive cells

scientific article published on 23 May 2008

TNF receptor signaling inhibits cardiomyogenic differentiation of cardiac stem cells and promotes a neuroadrenergic-like fate

scientific article published on 2 September 2016

TRPA1 channel contributes to myocardial ischemia-reperfusion injury

scientific article published on 08 February 2019

Targeting phosphatidylinositol 3-kinase-Akt through hepatocyte growth factor for cardioprotection

scientific article published on April 2013

Ten Years at the Helm of Circulation Research

scientific article published on 06 June 2019

The 10 Most Read Articles Published in Circulation Research in 2016

scientific article published on 01 March 2017

The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning ⬇️

scientific article published on July 23, 2012

The Epigenetic Regulator HDAC1 Modulates Transcription of a Core Cardiogenic Program in Human Cardiac Mesenchymal Stromal Cells Through a p53-Dependent Mechanism

scientific article published on 9 August 2016

The Heme Oxygenase 1 Inducer (CoPP) Protects Human Cardiac Stem Cells against Apoptosis through Activation of the Extracellular Signal-regulated Kinase (ERK)/NRF2 Signaling Pathway and Cytokine Release ⬇️

scientific article published on August 9, 2012

The Impact Factor of Circulation Research Reaches Another New High

scientific article published on 01 August 2018

The Impact Factor of Circulation Research Reaches a New High

scientific article published in July 2017

The Impact Factor of Circulation Research Rises 25% ⬇️

scientific article published on August 15, 2013

The NHLBI-sponsored Consortium for preclinicAl assESsment of cARdioprotective therapies (CAESAR): a new paradigm for rigorous, accurate, and reproducible evaluation of putative infarct-sparing interventions in mice, rabbits, and pigs

scientific article

The Promise and Challenge of Induced Pluripotent Stem Cells for Cardiovascular Applications.

scientific article

The Role of Sodium-Hydrogen Ion Exchange in Patients Undergoing Coronary Artery Bypass Grafting ⬇️

scientific article published on January 1, 2003

The Ten Most Read Articles Published in Circulation Research in 2011 ⬇️

scientific article published on January 31, 2012

The beneficial effects of postinfarct cytokine combination therapy are sustained during long-term follow-up

scientific article published on 16 July 2009

The cardioprotection of the late phase of ischemic preconditioning is enhanced by postconditioning via a COX-2-mediated mechanism in conscious rats

scientific article published on 17 August 2007

The cornucopia of "pleiotropic" actions of statins: myogenesis as a new mechanism for statin-induced benefits?

scientific article published on January 2009

The late phase of ischemic preconditioning induces a prosurvival genetic program that results in marked attenuation of apoptosis

scientific article

The late phase of preconditioning and its natural clinical application--gene therapy

scientific article

The new circulation research: a manifesto

scientific article published in February 2010

The risk for myocardial infarction with cyclooxygenase-2 inhibitors

scientific article (publication date: 18 October 2005)

The role of TNF-alpha receptors p55 and p75 in acute myocardial ischemia/reperfusion injury and late preconditioning

scientific article published on 12 September 2008

The telomere-telomerase axis and the heart

scientific article published on November 2006

The ubiquitous role of nitric oxide in cardioprotection

scientific article

The usefulness of the anaerobic threshold in the assessment and prognostic evaluation of the patient with dyspnea.

scientific article published on January 2012

Time to end the war on cell therapy

scientific article published on 26 February 2020

Trainees in the Spotlight: Yet Another Addition to Our Portfolio

scientific article published on 01 March 2017

Transcription Factor STAT3 Serves as a Negative Regulator Controlling IgE Class Switching in Mice

scientific article published on 05 December 2018

Transcription factor-induced activation of cardiac gene expression in human c-kit+ cardiac progenitor cells

scientific article

Translational Research in Cardiovascular Repair: A Call for a Paradigm Shift

scientific article

Transplantation of bone marrow-derived very small embryonic-like stem cells attenuates left ventricular dysfunction and remodeling after myocardial infarction

scientific article published on 17 April 2008

Transplantation of expanded bone marrow-derived very small embryonic-like stem cells (VSEL-SCs) improves left ventricular function and remodelling after myocardial infarction

scientific article published on 12 July 2010

Tumor necrosis factor-alpha does not modulate ischemia/reperfusion injury in naïve myocardium but is essential for the development of late preconditioning

scientific article published in July 2004

Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor Cells

scientific article published on 05 May 2016

Use of fractional flow reserve versus stress perfusion scintigraphy after unstable angina. Effect on duration of hospitalization, cost, procedural characteristics, and clinical outcome

scientific article published in April 2003

Vascular endothelial growth factor in heart failure ⬇️

scientific article published on July 16, 2013

William Harvey and the Discovery of the Circulation of the Blood

scientific article published on 01 April 2019

William Harvey and the Discovery of the Circulation of the Blood

scientific article published on 01 May 2019

William Harvey and the Discovery of the Circulation of the Blood

scientific article

c-kit+ Cardiac stem cells alleviate post-myocardial infarction left ventricular dysfunction despite poor engraftment and negligible retention in the recipient heart

scientific article

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