List of works - Paul N. Black

A live-cell high-throughput screening assay for identification of fatty acid uptake inhibitors

scientific article published in January 2005

A revolution in biochemistry and molecular biology education informed by basic research to meet the demands of 21st century career paths

scientific article published on 11 June 2020

Affinity labeling fatty acyl-CoA synthetase with 9-p-azidophenoxy nonanoic acid and the identification of the fatty acid-binding site.

scientific article published in December 2000

Bacterial long chain fatty acid transport: gateway to a fatty acid-responsive signaling system

scientific article published on 30 August 2004

Carbon and Acyl Chain Flux during Stress-induced Triglyceride Accumulation by Stable Isotopic Labeling of the Polar Microalga Coccomyxa subellipsoidea C169.

scientific article published on 30 November 2016

Characterization of long-chain fatty acid uptake in Caulobacter crescentus.

scientific article

Characterization of the Fatty Acid-responsive Transcription Factor FadR

scientific article published in Journal of Biological Chemistry

Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death

scientific article published on 19 September 2015

Coherent anti-Stokes Raman scattering and spontaneous Raman spectroscopy and microscopy of microalgae with nitrogen depletion.

scientific article

Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast

scientific article published on 7 February 2005

Crystal structure of the long-chain fatty acid transporter FadL.

scientific article

Defining a relationship between dietary fatty acids and the cytochrome P450 system in a mouse model of fatty liver disease

scientific article

Deletion of Fatty Acid Transport Protein 2 (FATP2) in the mouse liver changes the metabolic landscape by increasing the expression of PPARα-regulated genes

scientific article published on 18 March 2020

Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology

scientific article published on 4 October 2017

Dietary polyunsaturated fatty acids (C18:2 omega6 and C18:3 omega3) do not suppress hepatic lipogenesis.

scientific article published on 4 July 2008

Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis

scientific article

Editorial [Hot Topic: Dietary Lipid Absorption (Guest Editors: C.C. DiRusso and P.N. Black)]

Evidence that His110 of the protein FadL in the outer membrane of Escherichia coli is involved in the binding and uptake of long-chain fatty acids: possible role of this residue in carboxylate binding.

scientific article published in September 1995

Fatty Acid Transport Proteins: Targeting FATP2 as a Gatekeeper Involved in the Transport of Exogenous Fatty Acids

scientific article published on 19 February 2016

Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking

scientific article

Fatty acid transport in Saccharomyces cerevisiae. Directed mutagenesis of FAT1 distinguishes the biochemical activities associated with Fat1p

scientific article

Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity

scientific article

Functional role of fatty acyl-coenzyme A synthetase in the transmembrane movement and activation of exogenous long-chain fatty acids. Amino acid residues within the ATP/AMP signature motif of Escherichia coli FadD are required for enzyme activity an

scientific article published on 28 May 2002

Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype

scientific article published on 08 July 2005

High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias

scientific article

Human fatty acid transport protein 2a/very long chain acyl-CoA synthetase 1 (FATP2a/Acsvl1) has a preference in mediating the channeling of exogenous n-3 fatty acids into phosphatidylinositol

scientific article

Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae.

scientific article published on 26 June 2017

Identification and characterization of small compound inhibitors of human FATP2

scientific article

Immune regulation and anti-cancer activity by lipid inflammatory mediators

scientific article published on 14 November 2018

Integrated quantitative analysis of nitrogen stress response in Chlamydomonas reinhardtii using metabolite and protein profiling

scientific article

Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation

article

Mechanistic studies of the long chain acyl-CoA synthetase Faa1p from Saccharomyces cerevisiae

scientific article

Modeling of rhythmic behavior in neutral lipid production due to continuous supply of limited nitrogen: mutual growth and lipid accumulation in microalgae

scientific article published on August 2014

Murine FATP alleviates growth and biochemical deficiencies of yeast fat1Delta strains.

scientific article published in July 2000

Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids

scientific article

Physical map location of the Escherichia coli gene encoding acyl coenzyme A synthetase ⬇️

scientific article published on December 1, 1992

Rapid detection and quantification of triacylglycerol by HPLC-ELSD in Chlamydomonas reinhardtii and Chlorella strains ⬇️

scientific article

Remodeling of Chlamydomonas Metabolism Using Synthetic Inducers Results in Lipid Storage during Growth

scientific article published on 09 September 2019

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

scientific article

Surface-enhanced Raman spectroscopy using gold-coated horizontally aligned carbon nanotubes.

scientific article

Targeting the fatty acid transport proteins (FATP) to understand the mechanisms linking fatty acid transport to metabolism

scientific article

The Acyl-CoA synthetases encoded within FAA1 and FAA4 in Saccharomyces cerevisiae function as components of the fatty acid transport system linking import, activation, and intracellular Utilization.

scientific article

The amino-terminal region of the long-chain fatty acid transport protein FadL contains an externally exposed domain required for bacteriophage T2 binding.

scientific article

Topology of the yeast fatty acid transport protein Fat1p: mechanistic implications for functional domains on the cytosolic surface of the plasma membrane

scientific article

Transmembrane movement of exogenous long-chain fatty acids: proteins, enzymes, and vectorial esterification

scientific article

Use of transposon TnphoA to identify genes for cell envelope proteins of Escherichia coli required for long-chain fatty acid transport: the periplasmic protein Tsp potentiates long-chain fatty acid transport.

scientific article

Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex.

scientific article

Yeast acyl-CoA synthetases at the crossroads of fatty acid metabolism and regulation

scientific article published on 16 May 2006

List of works by Paul N. Black

A live-cell high-throughput screening assay for identification of fatty acid uptake inhibitors

A revolution in biochemistry and molecular biology education informed by basic research to meet the demands of 21st century career paths

Affinity labeling fatty acyl-CoA synthetase with 9-p-azidophenoxy nonanoic acid and the identification of the fatty acid-binding site.

Bacterial long chain fatty acid transport: gateway to a fatty acid-responsive signaling system

Carbon and Acyl Chain Flux during Stress-induced Triglyceride Accumulation by Stable Isotopic Labeling of the Polar Microalga Coccomyxa subellipsoidea C169.

Characterization of long-chain fatty acid uptake in Caulobacter crescentus.

Characterization of the Fatty Acid-responsive Transcription Factor FadR

Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death

Coherent anti-Stokes Raman scattering and spontaneous Raman spectroscopy and microscopy of microalgae with nitrogen depletion.

Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast

Crystal structure of the long-chain fatty acid transporter FadL.

Defining a relationship between dietary fatty acids and the cytochrome P450 system in a mouse model of fatty liver disease

Deletion of Fatty Acid Transport Protein 2 (FATP2) in the mouse liver changes the metabolic landscape by increasing the expression of PPARα-regulated genes

Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology

Dietary polyunsaturated fatty acids (C18:2 omega6 and C18:3 omega3) do not suppress hepatic lipogenesis.

Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis

Editorial [Hot Topic: Dietary Lipid Absorption (Guest Editors: C.C. DiRusso and P.N. Black)]

Evidence that His110 of the protein FadL in the outer membrane of Escherichia coli is involved in the binding and uptake of long-chain fatty acids: possible role of this residue in carboxylate binding.

Fatty Acid Transport Proteins: Targeting FATP2 as a Gatekeeper Involved in the Transport of Exogenous Fatty Acids

Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking

Fatty acid transport in Saccharomyces cerevisiae. Directed mutagenesis of FAT1 distinguishes the biochemical activities associated with Fat1p

Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity

Functional role of fatty acyl-coenzyme A synthetase in the transmembrane movement and activation of exogenous long-chain fatty acids. Amino acid residues within the ATP/AMP signature motif of Escherichia coli FadD are required for enzyme activity an

Hepatic gene expression changes in mouse models with liver-specific deletion or global suppression of the NADPH-cytochrome P450 reductase gene. Mechanistic implications for the regulation of microsomal cytochrome P450 and the fatty liver phenotype

High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias

Human fatty acid transport protein 2a/very long chain acyl-CoA synthetase 1 (FATP2a/Acsvl1) has a preference in mediating the channeling of exogenous n-3 fatty acids into phosphatidylinositol

Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae.

Identification and characterization of small compound inhibitors of human FATP2

Immune regulation and anti-cancer activity by lipid inflammatory mediators

Integrated quantitative analysis of nitrogen stress response in Chlamydomonas reinhardtii using metabolite and protein profiling

Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation

Mechanistic studies of the long chain acyl-CoA synthetase Faa1p from Saccharomyces cerevisiae

Modeling of rhythmic behavior in neutral lipid production due to continuous supply of limited nitrogen: mutual growth and lipid accumulation in microalgae

Murine FATP alleviates growth and biochemical deficiencies of yeast fat1Delta strains.

Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids

Physical map location of the Escherichia coli gene encoding acyl coenzyme A synthetase ⬇️

Rapid detection and quantification of triacylglycerol by HPLC-ELSD in Chlamydomonas reinhardtii and Chlorella strains ⬇️

Remodeling of Chlamydomonas Metabolism Using Synthetic Inducers Results in Lipid Storage during Growth

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family

Surface-enhanced Raman spectroscopy using gold-coated horizontally aligned carbon nanotubes.

Targeting the fatty acid transport proteins (FATP) to understand the mechanisms linking fatty acid transport to metabolism

The Acyl-CoA synthetases encoded within FAA1 and FAA4 in Saccharomyces cerevisiae function as components of the fatty acid transport system linking import, activation, and intracellular Utilization.

The amino-terminal region of the long-chain fatty acid transport protein FadL contains an externally exposed domain required for bacteriophage T2 binding.

Topology of the yeast fatty acid transport protein Fat1p: mechanistic implications for functional domains on the cytosolic surface of the plasma membrane

Transmembrane movement of exogenous long-chain fatty acids: proteins, enzymes, and vectorial esterification

Use of transposon TnphoA to identify genes for cell envelope proteins of Escherichia coli required for long-chain fatty acid transport: the periplasmic protein Tsp potentiates long-chain fatty acid transport.

Vectorial acylation in Saccharomyces cerevisiae. Fat1p and fatty acyl-CoA synthetase are interacting components of a fatty acid import complex.

Yeast acyl-CoA synthetases at the crossroads of fatty acid metabolism and regulation