List of works - Robin J. Thomson

A Sulfonozanamivir Analogue has Potent Anti-influenza Virus Activity.

scientific article published on 17 February 2018

A sialosyl sulfonate as a potent inhibitor of influenza virus replication

scientific article published on 25 May 2017

A unique sialidase that cleaves the Neu5Gcalpha2-->5-O(glycolyl)Neu5Gc linkage: comparison of its specificity with that of three microbial sialidases toward four sialic acid dimers.

scientific article

Access to 3-O-Functionalized N-Acetylneuraminic Acid Scaffolds.

scientific article

Accessing C-1 phosphonylated 2-acylamino uronic acids via 2-nitro-glycals

scientific article published on 29 April 2011

Anti-influenza drugs: the development of sialidase inhibitors.

scientific article

Atypical group 1 neuraminidase pH1N1-N1 bound to a group 1 inhibitor

scientific article published on 3 September 2015

Catalysis by a new sialidase, deaminoneuraminic acid residue-cleaving enzyme (KDNase Sm), initially forms a less stable alpha-anomer of 3-deoxy-D-glycero-D-galacto-nonulosonic acid and is strongly inhibited by the transition state analogue, 2-deoxy-

scientific article published on February 1997

Complexity in influenza virus targeted drug design: interaction with human sialidases.

scientific article

Cracking the code for H5N1-bird flu and beyond.

scientific article

Diversity and distribution of the Caddisflies (Insecta: Trichoptera) of Ecuador

scientific article (publication date: 2017)

Efficient Blocking of Enterovirus 71 Infection by Heparan Sulfate Analogues Acting as Decoy Receptors

scientific article published on 05 August 2019

Functional and structural characterization of a heparanase

scientific article

Imaging of influenza virus sialidase activity in living cells

scientific article

Modelling, synthesis and biological evaluation of novel glucuronide-based probes of Vibrio cholerae sialidase.

scientific article published on 4 November 2005

New antiviral approaches for human parainfluenza: Inhibiting the haemagglutinin-neuraminidase

scientific article published on 03 April 2019

Novel 3,4-disubstituted-Neu5Ac2en derivatives as probes to investigate flexibility of the influenza virus sialidase 150-loop.

scientific article published on 6 June 2013

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

scientific article

Rapid access to uronic acid-based mimetics of Kdn2en from D-glucurono-6,3-lactone

scientific article published on 01 October 2000

Saturation transfer difference (STD) 1H-NMR experiments and in silico docking experiments to probe the binding of N-acetylneuraminic acid and derivatives to Vibrio cholerae sialidase

scientific article

Structural analysis of a designed inhibitor complexed with the hemagglutinin-neuraminidase of Newcastle disease virus

scientific article published in February 2006

Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt's lymphoma (BL) Daudi cells by NMR spectroscopy

scientific article published on 3 November 2016

Structural insights into human parainfluenza virus type-3 haemagglutinin-neuraminidase using unsaturated 3- N-substituted sialic acids as probes.

scientific article

Synthesis and biological evaluation of galactofuranosyl alkyl thioglycosides as inhibitors of mycobacteria

scientific article published on 06 May 2007

Synthesis and evaluation of galactofuranosyl N,N-dialkyl sulfenamides and sulfonamides as antimycobacterial agents.

scientific article published on 27 January 2007

Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility

scientific article

Unsaturated N-acetyl- D-glucosaminuronic acid glycosides as inhibitors of influenza virus sialidase.

scientific article

Uronosyl phosphonate-based sialidase inhibitor synthesis and conformational analysis.

scientific article published on 10 October 2012

cis-bis(pyridine)platinum(II) organoamides with unexpected growth inhibition properties and antitumor activity

scientific article published on September 4, 1992

Ralph W. Holzenthal – a mentor and friend retires

scientific article published on 11 July 2022

List of works by Robin J. Thomson

A Sulfonozanamivir Analogue has Potent Anti-influenza Virus Activity.

A sialosyl sulfonate as a potent inhibitor of influenza virus replication

A unique sialidase that cleaves the Neu5Gcalpha2-->5-O(glycolyl)Neu5Gc linkage: comparison of its specificity with that of three microbial sialidases toward four sialic acid dimers.

Access to 3-O-Functionalized N-Acetylneuraminic Acid Scaffolds.

Accessing C-1 phosphonylated 2-acylamino uronic acids via 2-nitro-glycals

Anti-influenza drugs: the development of sialidase inhibitors.

Atypical group 1 neuraminidase pH1N1-N1 bound to a group 1 inhibitor

Catalysis by a new sialidase, deaminoneuraminic acid residue-cleaving enzyme (KDNase Sm), initially forms a less stable alpha-anomer of 3-deoxy-D-glycero-D-galacto-nonulosonic acid and is strongly inhibited by the transition state analogue, 2-deoxy-

Complexity in influenza virus targeted drug design: interaction with human sialidases.

Cracking the code for H5N1-bird flu and beyond.

Diversity and distribution of the Caddisflies (Insecta: Trichoptera) of Ecuador

Efficient Blocking of Enterovirus 71 Infection by Heparan Sulfate Analogues Acting as Decoy Receptors

Functional and structural characterization of a heparanase

Imaging of influenza virus sialidase activity in living cells

Modelling, synthesis and biological evaluation of novel glucuronide-based probes of Vibrio cholerae sialidase.

New antiviral approaches for human parainfluenza: Inhibiting the haemagglutinin-neuraminidase

Novel 3,4-disubstituted-Neu5Ac2en derivatives as probes to investigate flexibility of the influenza virus sialidase 150-loop.

Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase

Rapid access to uronic acid-based mimetics of Kdn2en from D-glucurono-6,3-lactone

Saturation transfer difference (STD) 1H-NMR experiments and in silico docking experiments to probe the binding of N-acetylneuraminic acid and derivatives to Vibrio cholerae sialidase

Structural analysis of a designed inhibitor complexed with the hemagglutinin-neuraminidase of Newcastle disease virus

Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt's lymphoma (BL) Daudi cells by NMR spectroscopy

Structural insights into human parainfluenza virus type-3 haemagglutinin-neuraminidase using unsaturated 3- N-substituted sialic acids as probes.

Synthesis and biological evaluation of galactofuranosyl alkyl thioglycosides as inhibitors of mycobacteria

Synthesis and evaluation of galactofuranosyl N,N-dialkyl sulfenamides and sulfonamides as antimycobacterial agents.

Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility

Unsaturated N-acetyl- D-glucosaminuronic acid glycosides as inhibitors of influenza virus sialidase.

Uronosyl phosphonate-based sialidase inhibitor synthesis and conformational analysis.

cis-bis(pyridine)platinum(II) organoamides with unexpected growth inhibition properties and antitumor activity

﻿Ralph W. Holzenthal – a mentor and friend retires

Ralph W. Holzenthal – a mentor and friend retires