List of works - Soosung Kang

2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity

scientific article published on 10 July 2015

A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of CaV1.3 L-Type Calcium Channels

scientific article published on 03 September 2020

Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.

scientific article published on 19 March 2010

Antagonism of L-type Ca2+ channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics ⬇️

scientific article published on April 28, 2013

CF₃-Substituted Mollugin 2-(4-Morpholinyl)-ethyl ester as a Potential Anti-inflammatory Agent with Improved Aqueous Solubility and Metabolic Stability

scientific article published on 14 August 2018

CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease.

scientific article

Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3

scientific article published on 04 December 2019

Correction to Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.

scientific article published on 25 January 2016

Deciphering Fatty Acid Synthase Inhibition-Triggered Metabolic Flexibility in Prostate Cancer Cells through Untargeted Metabolomics

scientific article published on 10 November 2020

Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2.

scientific article

Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain.

scientific article

Electrostatic Control of Isoform Selective Inhibitor Binding in Nitric Oxide Synthase

scientific article

Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery

scientific article published on 06 August 2018

Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design.

scientific article published on 9 March 2018

Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase

scientific article published on 23 June 2015

Metal-Free Synthesis of N-Aryl-Substituted Azacycles from Cyclic Ethers Using POCl3

scientific article published on 10 May 2019

Microwave-assisted protection of primary amines as 2,5-dimethylpyrroles and their orthogonal deprotection.

scientific article published on 14 October 2013

Nitric Oxide Synthase Inhibitors That Interact with Both Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity

scientific article

Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus

scientific article published on June 2015

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.

scientific article published on 17 August 2017

Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.

scientific article

Physiological involvement of presynaptic L-type voltage dependent calcium channels in GABA release of cerebellar molecular layer interneurons

scientific article published on 03 June 2020

Practical direct synthesis of N-aryl-substituted azacycles from N-alkyl protected arylamines using TiCl4 and DBU

scientific article published on 23 June 2020

Regulation of aldosterone secretion by Cav1.3.

scientific article published on 21 April 2016

Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease

scientific article

Structural and biological studies on bacterial nitric oxide synthase inhibitors

scientific article

Structure-based design of bacterial nitric oxide synthase inhibitors.

scientific article

Structure–Activity Relationship of N,N′-Disubstituted Pyrimidinetriones as CaV1.3 Calcium Channel-Selective Antagonists for Parkinson’s Disease ⬇️

scientific article published on May 23, 2013

Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB.

scientific article

Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability

scientific article

The Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme–Inhibitor Interactions in Nitric Oxide Synthases

scientific article

List of works by Soosung Kang

2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity

A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of CaV1.3 L-Type Calcium Channels

Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.

Antagonism of L-type Ca2+ channels CaV1.3 and CaV1.2 by 1,4-dihydropyrimidines and 4H-pyrans as dihydropyridine mimics ⬇️

CF₃-Substituted Mollugin 2-(4-Morpholinyl)-ethyl ester as a Potential Anti-inflammatory Agent with Improved Aqueous Solubility and Metabolic Stability

CaV1.3-selective L-type calcium channel antagonists as potential new therapeutics for Parkinson's disease.

Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3

Correction to Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.

Deciphering Fatty Acid Synthase Inhibition-Triggered Metabolic Flexibility in Prostate Cancer Cells through Untargeted Metabolomics

Design, synthesis, biological and structural evaluation of functionalized resveratrol analogues as inhibitors of quinone reductase 2.

Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain.

Electrostatic Control of Isoform Selective Inhibitor Binding in Nitric Oxide Synthase

Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery

Exploring G Protein-Coupled Receptors (GPCRs) Ligand Space via Cheminformatics Approaches: Impact on Rational Drug Design.

Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase

Metal-Free Synthesis of N-Aryl-Substituted Azacycles from Cyclic Ethers Using POCl3

Microwave-assisted protection of primary amines as 2,5-dimethylpyrroles and their orthogonal deprotection.

Nitric Oxide Synthase Inhibitors That Interact with Both Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity

Nitric Oxide Synthase as a Target for Methicillin-Resistant Staphylococcus aureus

Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors.

Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.

Physiological involvement of presynaptic L-type voltage dependent calcium channels in GABA release of cerebellar molecular layer interneurons

Practical direct synthesis of N-aryl-substituted azacycles from N-alkyl protected arylamines using TiCl4 and DBU

Regulation of aldosterone secretion by Cav1.3.

Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease

Structural and biological studies on bacterial nitric oxide synthase inhibitors

Structure-based design of bacterial nitric oxide synthase inhibitors.

Structure–Activity Relationship of N,N′-Disubstituted Pyrimidinetriones as CaV1.3 Calcium Channel-Selective Antagonists for Parkinson’s Disease ⬇️

Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB.

Synthesis of mevalonate- and fluorinated mevalonate prodrugs and their in vitro human plasma stability

The Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme–Inhibitor Interactions in Nitric Oxide Synthases