List of works - Jeffrey R Liddell

An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII.

scientific article published on 15 December 2011

Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?

scientific article published on 18 August 2017

Astrocytes retain their antioxidant capacity into advanced old age.

scientific article published on September 2010

C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

scientific article

Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture.

scientific article published on 30 August 2016

Copper modulates the large dense core vesicle secretory pathway in PC12 cells.

scientific article

Copper-ATSM as a Treatment for ALS: Support from Mutant SOD1 Models and Beyond

scientific article published on 04 November 2020

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

scientific article

Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates

scientific article published on 27 January 2012

Endogenous glutathione and catalase protect cultured rat astrocytes from the iron-mediated toxicity of hydrogen peroxide.

scientific article

Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes.

scientific article published in December 2006

Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity

scientific article published in August 2006

Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes

scientific article

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

scientific article

Lipophilic adamantyl- or deferasirox-based conjugates of desferrioxamine B have enhanced neuroprotective capacity: implications for Parkinson disease

scientific article published on 4 February 2013

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.

scientific article published on 14 March 2014

Mitochondrial metals as a potential therapeutic target in neurodegeneration

scientific article published on April 2014

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation.

scientific article

Nexus between mitochondrial function, iron, copper and glutathione in Parkinson's disease

scientific article published on 31 May 2017

Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.

scientific article

Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43.

scientific article

Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry

scientific article published on 17 October 2013

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes

scientific article published on 26 February 2016

Subcellular localization of a fluorescent derivative of CuII(atsm) offers insight into the neuroprotective action of CuII(atsm).

scientific article published on 19 September 2011

Sustained hydrogen peroxide stress decreases lactate production by cultured astrocytes.

scientific article published in September 2009

Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration.

scientific article published on 21 August 2015

Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis.

scientific article published on 19 August 2013

X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorder

scientific article

Zn II(atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism.

scientific article

List of works by Jeffrey R Liddell

An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis(4-methylthiosemicarbazonato)copperII.

Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?

Astrocytes retain their antioxidant capacity into advanced old age.

C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture.

Copper modulates the large dense core vesicle secretory pathway in PC12 cells.

Copper-ATSM as a Treatment for ALS: Support from Mutant SOD1 Models and Beyond

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder

Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates

Endogenous glutathione and catalase protect cultured rat astrocytes from the iron-mediated toxicity of hydrogen peroxide.

Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes.

Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity

Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

Lipophilic adamantyl- or deferasirox-based conjugates of desferrioxamine B have enhanced neuroprotective capacity: implications for Parkinson disease

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.

Mitochondrial metals as a potential therapeutic target in neurodegeneration

Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation.

Nexus between mitochondrial function, iron, copper and glutathione in Parkinson's disease

Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.

Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43.

Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes

Subcellular localization of a fluorescent derivative of CuII(atsm) offers insight into the neuroprotective action of CuII(atsm).

Sustained hydrogen peroxide stress decreases lactate production by cultured astrocytes.

Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration.

Therapeutic effects of CuII(atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis.

X-ray fluorescence imaging reveals subcellular biometal disturbances in a childhood neurodegenerative disorder

Zn II(atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism.