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List of works by Esteban N. Gurzov

Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets

scientific article

BIM Deficiency Protects NOD Mice From Diabetes by Diverting Thymocytes to Regulatory T Cells

scientific article published on 06 May 2015

Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction

scientific article published on 12 April 2011

Can GABA turn pancreatic α-cells into β-cells?

scientific article published on 01 November 2018

Cyclin E1 knockdown induces apoptosis in cancer cells.

scientific article published in July 2006

Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis

scientific article

Differential regulation of pro-inflammatory cytokine signalling by PTPs in pancreatic β-cells

scientific article

Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance

scientific article

Genes associated with adult axon regeneration promoted by olfactory ensheathing cells: a new role for matrix metalloproteinase 2.

scientific article published on May 2006

Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

scientific article published on 31 August 2009

Graphene oxide inhibits hIAPP amyloid fibrillation and toxicity in insulin-producing NIT-1 cells

scientific article published on 2 December 2015

Hepatic oxidative stress promotes insulin-STAT-5 signaling and obesity by inactivating protein tyrosine phosphatase N2

scientific article

Inactivation of Protein Tyrosine Phosphatases Enhances Interferon Signaling in Pancreatic Islets

scientific article published on 2 March 2015

Inhibition of Y1 receptor signaling improves islet transplant outcome.

scientific article published on 8 September 2017

Inhibition of hIAPP Amyloid Aggregation and Pancreatic β-Cell Toxicity by OH-Terminated PAMAM Dendrimer.

scientific article published on 25 January 2016

JNK Activation of BIM Promotes Hepatic Oxidative Stress, Steatosis, and Insulin Resistance in Obesity.

scientific article

JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

scientific article

JunB protects β-cells from lipotoxicity via the XBP1-AKT pathway

scientific article

Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System

scientific article published on 6 May 2015

Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice

scientific article

MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA.

scientific article published on January 2010

NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes

scientific article published on 19 May 2022

Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

scientific article published on 25 October 2018

PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.

scientific article

Pancreatic β-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species.

scientific article published on 16 February 2016

Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation

scientific article published on 15 August 2011

Paradoxical antiproliferative effect by a murine mammary tumor-derived epithelial cell line

scientific article

Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes

scientific article published on 07 July 2016

Protein tyrosine phosphatases: molecular switches in metabolism and diabetes

scientific article published on January 2015

Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis

scientific article published on 24 July 2009

Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation.

scientific article published on 16 October 2017

Sweet Killing in Obesity and Diabetes: The Metabolic Role of the BH3-only Protein BIM

scientific article published on 21 July 2018

TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.

scientific article published on 19 November 2012

Targeting c-Jun and JunB proteins as potential anticancer cell therapy

scientific article (publication date: 24 January 2008)

The JAK/STAT pathway in obesity and diabetes

scientific article published on 12 March 2016

The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity

scientific article published on 13 March 2014

The transcription factor B-cell lymphoma (BCL)-6 modulates pancreatic {beta}-cell inflammatory responses

scientific article published on 29 December 2010

The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells

scientific article

Zinc-coordination and C-peptide complexation: a potential mechanism for the endogenous inhibition of IAPP aggregation

scientific article

p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity

scientific article published on April 2016

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