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List of works by Richard van Breemen

(+/-)-(1S,2R,5S)-5-Amino-2-fluorocyclohex-3-enecarboxylic acid. A potent GABA aminotransferase inactivator that irreversibly inhibits via an elimination-aromatization pathway

scientific article published on December 2006

A Phase II Randomized Trial of Lycopene-Rich Tomato Extract Among Men with High-Grade Prostatic Intraepithelial Neoplasia. ⬇️

scientific article published on October 2015

A dual-isotope-labeling method of studying the bioavailability of hexaglutamyl folic acid relative to that of monoglutamyl folic acid in humans by using multiple orally administered low doses

scientific article published on 01 November 2006

A liquid chromatography-mass spectrometry method for the quantification of bioavailability and bioconversion of beta-carotene to retinol in humans.

scientific article

A mechanism for substrate-Induced formation of 6-hydroxyflavin mononucleotide catalyzed by C30A trimethylamine dehydrogenase.

scientific article published in November 2003

A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines

scientific article published on 01 May 2000

A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C

scientific article

A round robin approach to the analysis of bisphenol A (BPA) in human blood samples.

scientific article

A standardized Humulus lupulus (L.) ethanol extract partially prevents ovariectomy-induced bone loss in the rat without induction of adverse effects in the uterus

scientific article published on 2 August 2017

AOAC SMPR 2016.017

scientific article published on 01 January 2017

Absorption and subcellular localization of lycopene in human prostate cancer cells.

scientific article published in November 2006

Activated phase II metabolites: comparison of alkylation by 1-O-acyl glucuronides and acyl sulfates

scientific article published on 01 January 1986

Activity-guided isolation of antioxidative constituents of Cotinus coggygria

scientific article published on 01 December 2000

Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity

scientific article published in March 2003

Acylation of albumin by 1-O-acyl glucuronides

scientific article published on May 1985

Affinity selection-mass spectrometry for the discovery of pharmacologically active compounds from combinatorial libraries and natural products

scientific article published on 18 August 2020

Alkylation of 2'-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical.

scientific article published in February 1998

An LC-MS method for analyzing total resveratrol in grape juice, cranberry juice, and in wine

scientific article

An experimental implementation of chemical subtraction.

scientific article published on 17 December 2007

An improved LC-MS/MS method for the quantification of prostaglandins E(2) and D(2) production in biological fluids

scientific article published on 29 September 2007

Analysis and screening of combinatorial libraries using mass spectrometry

scientific article

Analysis of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors using liquid chromatography-electrospray mass spectrometry

scientific article

Analysis of GAA/TTC DNA triplexes using nuclear magnetic resonance and electrospray ionization mass spectrometry.

scientific article

Analysis of age-related changes in psychosine metabolism in the human brain

scientific article published on 26 February 2018

Analysis of lanthionine ketimine ethyl ester in mouse serum, whole blood and tissues using ultrahigh-pressure liquid chromatography/tandem mass spectrometry

scientific article published on 01 November 2018

Analysis of protein covalent modification by xenobiotics using a covert oxidatively activated tag: raloxifene proof-of-principle study

scientific article published on September 2005

Analysis, pharmacokinetics and therapeutic drug monitoring of mycophenolic acid

scientific article published on 01 July 1998

Analytical methods for quantitation of prenylated flavonoids from hops.

scientific article published on January 2013

Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1. ⬇️

scientific article published on 23 September 2008

Antioxidant effects of lycopene in African American men with prostate cancer or benign prostate hyperplasia: a randomized, controlled trial

scientific article

Antiproliferative and quinone reductase-inducing activities of withanolides derivatives

scientific article

Antiviral activities of hemp cannabinoids

scientific article published in 2023

Application of an immobilized digestive enzyme assay to measure chemical and enzymatic hydrolysis of the cyclic peptide antibiotic lysobactin.

scientific article published on July 1993

Applications of pulsed ultrafiltration-mass spectrometry

scientific article

Assays of ligand-human serum albumin binding using pulsed ultrafiltration and liquid chromatography-mass spectrometry

scientific article

Associations between functional polymorphisms in antioxidant defense genes and urinary oxidative stress biomarkers in healthy, premenopausal women.

scientific article published on 9 November 2011

Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry of Carotenoids

scientific article

Autonomic denervation of lymphoid organs leads to epigenetic immune atrophy in a mouse model of Krabbe disease.

scientific article published in December 2007

Axonopathy is a compounding factor in the pathogenesis of Krabbe disease.

scientific article published on 4 March 2011

Binding ensemble profiling with photoaffinity labeling (BEProFL) approach: mapping the binding poses of HDAC8 inhibitors

scientific article

Binding of the hop (Humulus lupulus L.) chalcone xanthohumol to cytosolic proteins in Caco-2 intestinal epithelial cells

scientific article

Bioactivation of the selective estrogen receptor modulator acolbifene to quinone methides.

scientific article published on February 2005

Bioactivation of the selective estrogen receptor modulator desmethylated arzoxifene to quinoids: 4'-fluoro substitution prevents quinoid formation.

scientific article

Bioactive compounds from the fern Lepisorus contortus ⬇️

scientific article

Bioactive lysophosphatidylcholine 16:0 and 18:0 are elevated in lungs of asthmatic subjects

scientific article published on 5 December 2013

Bioefficacy of beta-carotene dissolved in oil studied in children in Indonesia

scientific article

Biological and chemical standardization of a hop (Humulus lupulus) botanical dietary supplement

scientific article

Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.

scientific article published in May 1997

Biotransformation of the chemopreventive agent 2',4',4-trihydroxychalcone (isoliquiritigenin) by UDP-glucuronosyltransferases

scientific article published on 24 July 2008

Bisphenol A (BPA) Found in Humans and Water in Three Geographic Regions with Distinctly Different Levels of Economic Development.

scientific article published on 12 January 2014

Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epithelium

scientific article

Black Cohosh

article

Black cohosh (Cimicifuga racemosa L.) protects against menadione-induced DNA damage through scavenging of reactive oxygen species: bioassay-directed isolation and characterization of active principles

scientific article published in November 2002

Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor.

scientific article

Botanical Integrity: Part 2: Traditional and Modern Analytical Approaches

scientific article published on 01 January 2016

Botanical Integrity: The Importance of the Integration of Chemical, Biological, and Botanical Analyses, and the Role of DNA Barcoding

scientific article published on 01 January 2015

Caco-2 cell permeability assays to measure drug absorption.

scientific article published on August 2005

Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice

scientific article

Cancer chemopreventive potential of aromathecins and phenazines, novel natural product derivatives.

scientific article published on December 2010

Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants

publication published on 10 January 2022

Carotenoid composition of marigold (Tagetes erecta) flower extract used as nutritional supplement

scientific article (publication date: October 1999)

Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase.

scientific article

Catherine Fenselau: A distinguished career dedicated to biomedical mass spectrometry

scientific article published on 01 February 2020

Characterization of acyl-linked glucuronides by electron impact and fast atom bombardment mass spectrometry

scientific article published in August 1988

Characterization of cisplatin adducts of oligonucleotides by fast atom bombardment mass spectrometry.

scientific article

Characterization of oxygen-linked glucuronides by laser desorption mass spectrometry

scientific article published on June 1984

Characterization of two new variants of human catechol O-methyltransferase in vitro.

scientific article

Chemical and biological characterization and clinical evaluation of botanical dietary supplements: a phase I red clover extract as a model.

scientific article published on June 2004

Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles

scientific article published on 13 August 2013

Chemopreventive effects of soy protein and purified soy isoflavones on DMBA-induced mammary tumors in female Sprague-Dawley rats

scientific article published in January 2001

Chlorination diversifies Cimicifuga racemosa triterpene glycosides. ⬇️

scientific article published on 08 June 2007

Cimipronidine, a cyclic guanidine alkaloid from Cimicifuga racemosa.

scientific article

Classification of Flavonoid Metabolomes via Data Mining and Quantification of Hydroxyl NMR Signals

scientific article published on 26 March 2020

Coagulopathy After Synthetic Cannabinoid Use: A Case Report

scientific article published on 27 August 2019

Collision cross-section determination and tandem mass spectrometric analysis of isomeric carotenoids using electrospray ion mobility time-of-flight mass spectrometry

scientific article

Collision-induced dissociation of phenethylamides: role of ion-neutral complex.

scientific article published in September 2017

Combined hematopoietic and lentiviral gene-transfer therapies in newborn Twitcher mice reveal contemporaneous neurodegeneration and demyelination in Krabbe disease

scientific article published on 01 June 2009

Comment on "Optimal Exposure Biomarkers for Nonpersistent Chemicals in Environmental Epidemiology".

scientific article published on April 2016

Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides.

scientific article

Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense) ⬇️

scientific article

Competitive enzymatic interactions determine the relative amounts of prostaglandins E2 and D2.

scientific article

Confirmation of drug delivery after liver chemoembolization: direct tissue doxorubicin measurement by UHPLC-MS-MS.

scientific article

Confusion regarding anticoagulant coumarins in dietary supplements

scientific article published on 01 December 2004

Continuous-flow fast atom bombardment mass spectrometry of oligonucleotides.

scientific article published in April 1991

Correction to Screening Natural Products for Inhibitors of Quinone Reductase-2 Using Ultrafiltration LC–MS

article

Correction to The Multiple Biological Targets of Hops and Bioactive Compounds

scientific article published on 08 August 2019

Coumaroyl iridoids and a depside from cranberry (Vaccinium macrocarpon). ⬇️

scientific article published on 2 February 2007

Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa. ⬇️

scientific article published on 13 January 2016

Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale)

scientific article

Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents

scientific article

D,L-alpha-difluoromethylornithine inhibits human cytomegalovirus replication ⬇️

scientific article published on April 1, 1984

DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health.

scientific article published on 16 August 2017

DNA oxidation induced by cyclooxygenase-2.

scientific article published in April 2001

Degradation of peptide drugs by immobilized digestive proteases

scientific article published in May 1991

Derivatives of dicyclopentadiene in ground water

scientific article published on 01 March 1987

Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential

scientific article published on 8 March 2013

Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2.

scientific article

Detection of reactive metabolites using isotope-labeled glutathione trapping and simultaneous neutral loss and precursor ion scanning with ultra-high-pressure liquid chromatography triple quadruple mass spectrometry

scientific article published on 25 March 2015

Detection of the neurotoxin psychosine in samples of peripheral blood: application in diagnostics and follow-up of Krabbe disease

scientific article published on July 2012

Determination of absolute configurations of 4-hydroxyequilenin-cytosine and -adenine adducts by optical rotatory dispersion, electronic circular dichroism, density functional theory calculations, and mass spectrometry.

scientific article published on 05 August 2008

Determination of bisphenol A-glucuronide in human urine using ultrahigh-pressure liquid chromatography/tandem mass spectrometry.

scientific article published in February 2016

Determination of folates in human plasma using hydrophilic interaction chromatography-tandem mass spectrometry

scientific article published in November 2001

Development of Safe and Effective Botanical Dietary Supplements

scientific article (publication date: 12 November 2015)

Development of a Magnetic Microbead Affinity Selection Screen (MagMASS) Using Mass Spectrometry for Ligands to the Retinoid X Receptor-α.

scientific article published on 13 December 2016

Development of a method for quantitation of retinol and retinyl palmitate in human serum using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.

scientific article

Development of a screening assay for ligands to the estrogen receptor based on magnetic microparticles and LC-MS.

scientific article published on January 2008

Diarylheptanoids from Dioscorea villosa (Wild Yam)

scientific article published on 17 December 2012

Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo

scientific article published on 20 March 2013

Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation.

scientific article

Disposition of hop prenylflavonoids in human breast tissue

scientific article

Distribution of C16:0, C18:0, C24:1, and C24:0 sulfatides in central nervous system lipid rafts by quantitative ultra-high-pressure liquid chromatography tandem mass spectrometry.

scientific article

Does doxorubicin survive thermal ablation? Results of an ex vivo bench top study.

scientific article published in January 2018

Dysfunction of platelet-derived growth factor receptor α (PDGFRα) represses the production of oligodendrocytes from arylsulfatase A-deficient multipotential neural precursor cells

scientific article

Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.

scientific article

Effects of lycopene on protein expression in human primary prostatic epithelial cells.

scientific article

Effects of oral dosing paradigms (gavage versus diet) on pharmacokinetics and pharmacodynamics

scientific article published on 01 September 2006

Effects of ozone and oxygen on the degradation of carotenoids in an aqueous model system

scientific article published in October 2000

Effects of vitamin K1 treatment on plasma concentrations of long-acting anticoagulant rodenticide enantiomers following inhalation of contaminated synthetic cannabinoids

scientific article published on 18 November 2019

Electrospray Liquid Chromatography/Mass Spectrometry of Ginsenosides

scientific article published in 2005

Enhanced ionization of phosphorylated peptides during MALDI TOF mass spectrometry.

scientific article

Enhanced sensitivity of peptide analysis by fast-atom bombardment mass spectrometry using nitrocellulose as a substrate.

scientific article published in February 1989

Ensuring the safety of botanical dietary supplements

scientific article published on 01 February 2008

Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase

scientific article published in April 2004

Equine estrogen metabolite 4-hydroxyequilenin induces DNA damage in the rat mammary tissues: formation of single-strand breaks, apurinic sites, stable adducts, and oxidized bases

scientific article published in December 2001

Erratum to: A round robin approach to the analysis of bisphenol a (BPA) in human blood samples.

scientific article published on 8 March 2016

Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.

scientific article

Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus

scientific article published on 21 January 2009

Estrogens and congeners from spent hops (Humulus lupulus).

scientific article

Ethanol inhibits benzo[a]pyrene-DNA adduct removal and increases 8-oxo-deoxyguanosine formation in human mammary epithelial cells

scientific article published on January 2004

Ethiodized oil uptake does not predict doxorubicin drug delivery after chemoembolization in VX2 liver tumors

scientific article

Evaluation of Major Caffeic Acid Derivatives inEchinacea purpureaDietary Supplements by HPLC with Photodiode Array Detection and Electrospray Mass Spectrometry

scientific article published on 31 March 2005

Evaluation of commercial ginkgo and echinacea dietary supplements for colchicine using liquid chromatography-tandem mass spectrometry

scientific article published on 01 September 2002

Evaluation of cyclooxygenase-2 inhibitors using pulsed ultrafiltration mass spectrometry.

scientific article published in August 2000

Evaluation of estrogenic activity of licorice species in comparison with hops used in botanicals for menopausal symptoms

scientific article published on 12 July 2013

Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms

scientific article published in May 2001

Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats.

scientific article

Evidence for Chemopreventive and resilience activity of licorice: Glycyrrhiza glabra and G. inflata extracts modulate estrogen metabolism in ACI rats

scientific article published on 04 October 2018

Evidence supporting the conceptual framework of cancer chemoprevention in canines.

scientific article

Extraction of carotenoids from feces, enabling the bioavailability of beta-carotene to be studied in Indonesian children

scientific article

Finding the bad actor: Challenges in identifying toxic constituents in botanical dietary supplements

scientific article published on 21 December 2018

Flavonoid constituents of Chorizanthe diffusa with potential cancer chemopreventive activity

scientific article published on 01 January 1999

Flaxseed enriched diet-mediated reduction in ovarian cancer severity is correlated to the reduction of prostaglandin E(2) in laying hen ovaries

scientific article published on 14 August 2013

Food matrix effects on bioaccessibility of β-carotene can be measured in an in vitro gastrointestinal model

scientific article published on 15 January 2014

Formation of (2R)- and (2S)-8-Prenylnaringenin Glucuronides by Human UDP-Glucuronosyltransferases

scientific article published on 11 October 2019

Formylated peptides from cyanogen bromide digests identified by fast atom bombardment mass spectrometry

scientific article published in April 1990

From serendipity to rational antituberculosis drug discovery of mefloquine-isoxazole carboxylic acid esters

scientific article published in November 2009

Functional and structural comparisons of cysteine residues in the Val108 wild type and Met108 variant of human soluble catechol O-methyltransferase.

scientific article published in April 2005

GABAergic phthalide dimers from Angelica sinensis (Oliv.) Diels

scientific article published on 01 November 2006

Guanidine alkaloids and Pictet-Spengler adducts from black cohosh (Cimicifuga racemosa). ⬇️

scientific article published on March 2009

Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry.

scientific article

High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions.

scientific article

High-performance liquid chromatography with light-scattering detection and desorption chemical-ionization tandem mass spectrometry of milk fat triacylglycerols.

scientific article published in January 1995

High-performance liquid chromatography-electrospray mass spectrometry of retinoids

scientific article published on 01 July 1996

How do intermediate endpoint markers respond to lycopene in men with prostate cancer or benign prostate hyperplasia?

scientific article published on 01 August 2005

Human, rat, and mouse metabolism of resveratrol.

scientific article published in December 2002

Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS.

scientific article published on 4 October 2016

Identification and quantification of gingerols and related compounds in ginger dietary supplements using high-performance liquid chromatography-tandem mass spectrometry

scientific article

Identification of caffeic acid derivatives in Actea racemosa (Cimicifuga racemosa, black cohosh) by liquid chromatography/tandem mass spectrometry.

scientific article published in January 2003

Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol from hops (Humulus lupulus L.).

scientific article published on 12 April 2006

Identification of novel electrophilic metabolites of piper methysticum Forst (Kava).

scientific article

Identification of photocatalytic degradation products of diazinon in TiO2 aqueous suspensions using GC/MS/MS and LC/MS with quadrupole time-of-flight mass spectrometry.

scientific article published in August 2003

Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent

Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent.

scientific article published on 13 October 2007

Identification, synthesis, and biological evaluation of metabolites of the experimental cancer treatment drugs indotecan (LMP400) and indimitecan (LMP776) and investigation of isomerically hydroxylated indenoisoquinoline analogues as topoisomerase I

scientific article published on 7 December 2012

Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopr

scientific article

Improved Quantification of Free and Ester-Bound Gallic Acid in Foods and Beverages by UHPLC-MS/MS

scientific article published on 03 February 2016

In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent.

scientific article

In vitro formation of quinoid metabolites of the dietary supplement Cimicifuga racemosa (black cohosh).

scientific article published in July 2003

In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4.

scientific article published on 9 August 2011

In vitro metabolism of isoliquiritigenin by human liver microsomes

scientific article published on 15 November 2007

In vitro serotonergic activity of black cohosh and identification of N(omega)-methylserotonin as a potential active constituent ⬇️

scientific article

In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus L.). ⬇️

scientific article published on 16 May 2006

In vivo estrogenic comparisons of Trifolium pratense (red clover) Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin

scientific article

Inactivation of C30A trimethylamine dehydrogenase by N-cyclopropyl-alpha-methylbenzylamine, 1-phenylcyclopropylamine, and phenylhydrazine.

scientific article published in July 2001

Inactivation of monoamine oxidase B by 1-phenylcyclopropylamine: mass spectral evidence for the flavin adduct

scientific article

Increasing the throughput and productivity of Caco-2 cell permeability assays using liquid chromatography-mass spectrometry: application to resveratrol absorption and metabolism

scientific article published on December 2003

Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A

scientific article

Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells.

scientific article published on April 2011

Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens

scientific article published on 01 July 1998

Inhibition of human cytochrome P450 enzymes by hops (Humulus lupulus) and hop prenylphenols

scientific article published on 14 December 2013

Inhibition of rat mammary tumorigenesis by concord grape juice constituents.

scientific article published on December 2003

Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages.

scientific article published on 4 January 2007

Integrated standardization concept for Angelica botanicals using quantitative NMR

scientific article

Ion mobility-mass spectrometry for the separation and analysis of procyanidins

scientific article published on 18 June 2019

Isolation and characterization of miscellaneous secondary metabolites of Deprea subtriflora.

scientific article published in August 2003

Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata. ⬇️

scientific article

Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A.

scientific article

Isolation of linoleic acid as an estrogenic compound from the fruits of Vitex agnus-castus L. (chaste-berry).

scientific article published on January 2004

Isotopic tracer techniques for studying the bioavailability and bioefficacy of dietary carotenoids, particularly beta-carotene, in humans: a review

scientific article

K-targeted metabolomic analysis extends chemical subtraction to DESIGNER extracts: selective depletion of extracts of hops (Humulus lupulus).

scientific article published on December 2014

LC-MS-MS Analysis of Brodifacoum Isomers in Rat Tissue

scientific article published on 23 February 2016

Levels of plasma sulfatides C18 : 0 and C24 : 1 correlate with disease status in relapsing-remitting multiple sclerosis

scientific article

Lipidated steroid saponins from Dioscorea villosa (wild yam).

scientific article published on 19 August 2013

Liquid chromatography-mass spectrometry of cis- and all-trans-lycopene in human serum and prostate tissue after dietary supplementation with tomato sauce

scientific article

Liquid chromatography/electrospray tandem mass spectrometry of terpenoid lactones in Ginkgo biloba ⬇️

scientific article published on March 2005

Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate.

scientific article

Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.

scientific article published on 17 January 2018

METABOLISM OF 8-PRENYLNARINGENIN, A POTENT PHYTOESTROGEN FROM HOPS (HUMULUS LUPULUS), BY HUMAN LIVER MICROSOMES

scientific article (publication date: February 2004)

Magnetic Microbead Affinity Selection Screening (MagMASS) of Botanical Extracts for Inhibitors of 15-Lipoxygenase

scientific article

Mass spectrometric dereplication of nitrogen-containing constituents of black cohosh (Cimicifuga racemosa L.).

scientific article published on 9 December 2011

Mass spectrometry-based screening for inhibitors of beta-amyloid protein aggregation

scientific article published on November 2005

Matrix-Assisted Laser Desorption/Ionization Imaging Portrays Locoregional Drug Delivery

scientific article published on 01 August 2018

Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry

scientific article

Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification.

scientific article published in January 2005

Mechanism of neuromuscular dysfunction in Krabbe disease.

scientific article

Metabolic screening using on-line ultrafiltration mass spectrometry ⬇️

scientific article published on 01 February 1998

Metabolism of Nω -methylserotonin, a serotonergic constituent of black cohosh (Cimicifuga racemosa, L. (Nutt.)), by human liver microsomes

scientific article

Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes

scientific article published in March 2005

Method development and validation for ultra-high pressure liquid chromatography/tandem mass spectrometry determination of multiple prostanoids in biological samples

scientific article published on January 2013

Method development and validation for ultra-high-pressure LC/MS/MS determination of hop prenylflavonoids in human serum

scientific article published on November 2012

Minor Withanolides from Physalis philadelphica: Structures, Quinone Reductase Induction Activities, and Liquid Chromatography (LC)-MS-MS Investigation as Artifacts.

Minor withanolides from Physalis philadelphica: structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts. ⬇️

scientific article published on May 2003

Modification of keap1 cysteine residues by sulforaphane

scientific article

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

scientific article

Multitargeted therapy of cancer by lycopene

scientific article published on 27 June 2008

NF-kappaB-inducing kinase regulates cyclooxygenase 2 gene expression in macrophages by phosphorylation of PU.1.

scientific article published on December 2007

NMR study of fumarprotocetraric acid, a complex lichen depsidone derivative fromCladonia furcata

scientific article published on 2 April 2003

Nature's palette: the search for natural blue colorants.

scientific article

Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.

scientific article published on 20 February 2014

New metabolic pathways for flavanones catalyzed by rat liver microsomes

scientific article published in April 2004

Nitrogen-Containing Constituents of Black Cohosh: Chemistry, Structure Elucidation, and Biological Activities

scientific article published on January 2015

No Clinically Relevant Pharmacokinetic Interactions of a Red Clover Dietary Supplement with Cytochrome P450 Enzymes in Women

scientific article published on 16 November 2020

Novel histone deacetylase 8 ligands without a zinc chelating group: exploring an 'upside-down' binding pose

scientific article

Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents ⬇️

scientific article published on 16 February 2012

Oral toxicity and pharmacokinetic studies of SHetA2, a new chemopreventive agent, in rats and dogs

scientific article published on 5 September 2012

Orthogonal Analysis Underscores the Relevance of Primary and Secondary Metabolites in Licorice.

scientific article published on 31 July 2014

Oxidation of raloxifene to quinoids: potential toxic pathways via a diquinone methide and o-quinones

scientific article published on July 2004

Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention.

scientific article published in December 2001

Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha.

scientific article

Persistence of psychosine in brain lipid rafts is a limiting factor in the therapeutic recovery of a mouse model for Krabbe disease

scientific article

Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements

scientific article published on 5 October 2015

Pharmacokinetic interactions of a hop dietary supplement with drug metabolism in peri-menopausal and post-menopausal women

scientific article published on 14 April 2020

Pharmacokinetic study of conventional sorafenib chemoembolization in a rabbit VX2 liver tumor model

scientific article published on May 2015

Pharmacokinetics and brain penetration of LF-3-88, (2-[5-[5-(2(S)-azetidinylmethoxyl)-3-pyridyl]-3-isoxazolyl]ethanol), a selective α4β2-nAChR partial agonist and promising antidepressant

scientific article published on 23 November 2012

Pharmacokinetics of 23-epi-26-deoxyactein in women after oral administration of a standardized extract of black cohosh.

scientific article published on 23 December 2009

Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops.

scientific article

Photoreactive "nanorulers" detect a novel conformation of full length HDAC3-SMRT complex in solution

scientific article published on 02 October 2013

Phytochemistry of cimicifugic acids and associated bases in Cimicifuga racemosa root extracts

scientific article published on March 2009

Phytoconstituents from Vitex agnus-castus fruits ⬇️

scientific article

Pivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophages

scientific article

Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry

scientific article published on 9 May 2017

Prostate Cancer Risk and DNA Methylation Signatures in Aging Rats following Developmental BPA Exposure: A Dose-Response Analysis.

scientific article published on 11 July 2017

Psychosine accumulates in membrane microdomains in the brain of krabbe patients, disrupting the raft architecture.

scientific article

Psychosine enhances the shedding of membrane microvesicles: Implications in demyelination in Krabbe's disease

scientific article

Pulsed ultrafiltration mass spectrometry: a new method for screening combinatorial libraries.

scientific article published on June 1997

Quantitative analyses of beta-carotene and retinol in serum and feces in support of clinical bioavailability studies

scientific article

Quantitative analysis of 3alpha,6alpha,24-trihydroxy-24,24-di(trifluoromethyl)-5beta-cholane, a potent synthetic steroidal liver X receptor agonist in plasma using liquid chromatography-tandem mass spectrometry.

scientific article published on July 2010

Quantitative analysis of betulinic acid in mouse, rat and dog plasma using electrospray liquid chromatography/mass spectrometry

scientific article published in January 2003

Quantitative analysis of lycopene isomers in human plasma using high-performance liquid chromatography-tandem mass spectrometry

scientific article

Quantitative analysis of phytosterols in edible oils using APCI liquid chromatography-tandem mass spectrometry.

scientific article

Quantitative determination of N7-methyldeoxyguanosine and O6-methyldeoxyguanosine in DNA by LC-UV-MS-MS.

scientific article published in October 2002

Rapid Determination of Procyanidins Using MALDI-ToF/ToF Mass Spectrometry

scientific article published on 16 October 2018

Rapid quantitative analysis of 8-iso-prostaglandin-F(2alpha) using liquid chromatography-tandem mass spectrometry and comparison with an enzyme immunoassay method.

scientific article

Rates of peptide proteolysis measured using liquid chromatography and continuous-flow fast atom bombardment mass spectrometry

scientific article published in October 1992

Reaction of 1-O-acyl glucuronides with 4-(p-nitrobenzyl)pyridine

scientific article published on 01 March 1986

Reaction of bilirubin glucuronides with serum albumin

scientific article published on 01 December 1986

Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens

scientific article

Regulation of cyclooxygenase-2 expression by small GTPase Rac2 in bone marrow macrophages.

scientific article published on 15 June 2007

Resveratrol derivatives as promising chemopreventive agents with improved potency and selectivity

scientific article

Resveratrol in raw and baked blueberries and bilberries

scientific article published in September 2003

Resveratrol inhibits rhabdomyosarcoma cell proliferation

scientific article published in August 2005

Retinoic acid receptors and retinoids are up-regulated in the developing and adult rat prostate by neonatal estrogen exposure

scientific journal article

Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer

scientific article

Robert J. Cotter (1943-2012).

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Role of Mass Spectrometry in Establishing Safety and Efficacy of Botanical Dietary Supplements

scientific article published on 07 January 2020

Role of ammonium in the ionization of phosphatidylcholines during electrospray mass spectrometry.

scientific article

Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms: a randomized controlled trial

scientific article

Screening antioxidants using LC-MS: case study with cocoa

scientific article

Screening botanical extracts for quinoid metabolites.

scientific article published in November 2001

Screening drugs for metabolic stability using pulsed ultrafiltration mass spectrometry

scientific article

Screening for inhibitors of dihydrofolate reductase using pulsed ultrafiltration mass spectrometry.

scientific article

Screening for ligands of human retinoid X receptor-alpha using ultrafiltration mass spectrometry

scientific article published on 13 November 2007

Screening for natural chemoprevention agents that modify human Keap1.

scientific article

Screening for xenobiotic electrophilic metabolites using pulsed ultrafiltration-mass spectrometry

scientific article published on 01 June 1999

Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1.

scientific article

Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS

scientific article

Screening solution-phase combinatorial libraries using pulsed ultrafiltration/electrospray mass spectrometry.

scientific article published in December 1997

Secondary metabolites from Andrographis paniculata ⬇️

scientific article published on 01 March 2007

Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites.

scientific article

Separation and Quantification of Superwarfarin Rodenticide Diastereomers-Bromadiolone, Difenacoum, Flocoumafen, Brodifacoum, and Difethialone-in Human Plasma

scientific article published on 01 June 2020

Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis ⬇️

scientific article published on April 2006

Should Cytochrome P450 Inducers be Used to Accelerate Clearance of Brodifacoum from Poisoned Patients?

scientific article published on 01 March 2019

Simultaneous determination of all-trans, 9-cis, 13-cis retinoic acid and retinol in rat prostate using liquid chromatography-mass spectrometry

scientific article

Single Laboratory Validation of UHPLC-MS/MS Assays for Six Milk Thistle Flavonolignans in Human Serum

scientific article published on 19 August 2020

Single-Laboratory Validation of UHPLC-MS/MS Assays for Red Clover Isoflavones in Human Serum and Dietary Supplements

scientific article published on 01 July 2020

Sites of alkylation of human Keap1 by natural chemoprevention agents

scientific article

Solubilization and stabilization of carotenoids using micelles: Delivery of lycopene to cells in culture

article

Special issue honoring Catherine Fenselau

Species-specific Standardisation of Licorice by Metabolomic Profiling of Flavanones and Chalcones.

scientific article published on 13 November 2013

Spectrometric evidence for the flavin-1-phenylcyclopropylamine inactivator adduct with monoamine oxidase N.

scientific article published in May 2001

Standard Method Performance Requirements (SMPRs®) 2018.004: Determination of trans Resveratrol in Dietary Supplements and Dietary Ingredients

scientific article published on 01 July 2018

Standard Method Performance Requirements (SMPRs®) 2018.005: Determination of Kavalactones and/or Flavokavains from Kava (Piper methysticum)

scientific article published on 01 July 2018

Standard Method Performance Requirements (SMPRs®) 2018.006: Determination of Select Flavonoids from Skullcap

scientific article published on 01 July 2018

Standard Method Performance Requirements (SMPRs®) 2018.007: Identification of Skullcap in Raw Materials, Skullcap-Based Dietary Ingredients, and Dietary Supplements

scientific article published on 01 July 2018

Stimulated bronchial epithelial cells release bioactive lysophosphatidylcholine 16:0, 18:0, and 18:1.

scientific article published on 28 November 2013

Structural and functional consequences of inactivation of human glutathione S-transferase P1-1 mediated by the catechol metabolite of equine estrogens, 4-hydroxyequilenin.

scientific article published in April 2001

Structural modulation of oxidative metabolism in design of improved benzothiophene selective estrogen receptor modulators

scientific article published on 20 October 2008

Sulfatides in extracellular vesicles isolated from plasma of multiple sclerosis patients.

scientific article published on 25 August 2016

Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis.

scientific article published on 21 October 2015

Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone

scientific article

Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones

scientific article published in December 2001

Synthesis and reactivity of the catechol metabolites from the equine estrogen, 8,9-dehydroestrone.

scientific article published in June 2001

Systematic investigation of lycopene effects in LNCaP cells by use of novel large-scale proteomic analysis software

scientific article

Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers

scientific article published on February 2008

The Bile Sequestrant Cholestyramine Increases Survival in a Rabbit Model of Brodifacoum Poisoning

scholarly article by Matthew Lindeblad et al published 1 October 2018 in Toxicological Sciences

The Long-Lasting Rodenticide Brodifacoum Induces Neuropathology in Adult Male Rats.

scientific article published in September 2017

The Multiple Biological Targets of Hops and Bioactive Compounds

scientific article published on 22 January 2019

The University of Illinois at Chicago/National Institutes of Health Center for Botanical Dietary Supplements Research for Women's Health: from plant to clinical use.

scientific article published on February 2008

The apparent inhibition of inosine monophosphate dehydrogenase by mycophenolic acid glucuronide is attributable to the presence of trace quantities of mycophenolic acid

scientific article published on 01 July 1999

The chemical and biologic profile of a red clover (Trifolium pratense L.) phase II clinical extract.

scientific article published on March 2006

The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures.

scientific article published on 31 May 2016

The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.

scientific article published in September 1998

The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone

scientific article published on February 1999

The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile.

scientific article

The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells

scientific article published on 01 September 1997

The relative toxicity of brodifacoum enantiomers

scientific article published on 16 February 2019

The role of quality assurance and standardization in the safety of botanical dietary supplements

scientific article published on 16 March 2007

The soy isoflavone daidzein improves the capacity of tamoxifen to prevent mammary tumours.

scientific article published on 18 January 2005

Three new pentacyclic triterpenes and some flavonoids from the fruits of an Indian Ayurvedic plant Dendrophthoe falcata and their estrogen receptor binding activity. ⬇️

scientific article published in May 2006

Tomato sauce supplementation and prostate cancer: lycopene accumulation and modulation of biomarkers of carcinogenesis.

scientific article

Transarterial sorafenib chemoembolization: preliminary study of technical feasibility in a rabbit model

scientific article published on 17 March 2013

Treatment for long acting anticoagulant rodenticide poisoning - beyond INR monitoring?

scientific article published on 13 August 2018

Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized Sprague-Dawley rats

scientific article published on 01 January 2002

Ultrafiltration tandem mass spectrometry of estrogens for characterization of structure and affinity for human estrogen receptors

scientific article published on February 2005

Up-regulation of neurotrophic factors by cinnamon and its metabolite sodium benzoate: therapeutic implications for neurodegenerative disorders.

scientific article published on 9 March 2013

Use of high-performance liquid chromatography-tandem mass spectrometry to distinguish Panax ginseng C. A. Meyer (Asian ginseng) and Panax quinquefolius L. (North American ginseng)

scientific article published on 01 November 2000

Validation of a sensitive UHPLC-MS/MS method for cytochrome P450 probe substrates caffeine, tolbutamide, dextromethorphan, and alprazolam in human serum reveals drug contamination of serum used for research

scientific article published on 10 November 2019

Vitamin A equivalency and apparent absorption of beta-carotene in ileostomy subjects using a dual-isotope dilution technique

scientific article published on 5 February 2010

Vitamin A equivalency of beta-carotene in healthy adults: limitation of the extrinsic dual-isotope dilution technique to measure matrix effect

scientific article published on 24 November 2008

Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase.

scientific article published in August 2005

p-Hydroxybenzoic acid alkyl esters in Andrographis paniculata herbs, commercial extracts, and formulated products.

scientific article published in January 2003

α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies

scientific article published in Scientific Reports

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