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List of works by Frédérick A Mallette

Cellular Senescence in Postmitotic Cells: Beyond Growth Arrest

scientific article published on 25 April 2018

DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation

scientific article

Endogenous oxidative stress prevents telomerase-dependent immortalization of human endothelial cells.

scientific article published on 24 April 2010

Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation.

scientific article published on 12 June 2015

Human fibroblasts require the Rb family of tumor suppressors, but not p53, for PML-induced senescence.

scientific article published in January 2004

Molecular Regulation of Cellular Senescence by MicroRNAs: Implications in Cancer and Age-Related Diseases.

scientific article published on 18 May 2017

MyD88 Regulates the Expression of SMAD4 and the Iron Regulatory Hormone Hepcidin

scientific article published on 31 August 2018

Myc down-regulation as a mechanism to activate the Rb pathway in STAT5A-induced senescence.

scientific article

NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy

scientific article published on 20 February 2019

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy

scientific article published on 01 August 2020

Non-canonical ATM/MRN activities temporally define the senescence secretory program

scientific article published on 12 August 2020

Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity.

scientific article published on March 2014

Oncogenic Activities of IDH1/2 Mutations: From Epigenetics to Cellular Signaling

scientific article

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

scientific article

Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy.

scientific article published in October 2016

Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis

scientific article published on 30 November 2021

Targeting LINC00673 expression triggers cellular senescence in lung cancer

scientific article published on 07 December 2018

Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.

scientific article published in February 2018

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer

scientific article

The DNA damage signaling pathway connects oncogenic stress to cellular senescence.

scientific article published on 24 May 2007

The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

scientific article published on January 2007

The Rise of FXR1: Escaping Cellular Senescence in Head and Neck Squamous Cell Carcinoma.

scientific article

The fight of the Tudor domain "Royal family" for a broken DNA throne

scientific article published on 15 April 2012

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway

scientific article published on 14 September 2016

Transcriptome analysis and tumor suppressor requirements of STAT5-induced senescence

scientific article published on 01 June 2010

Translation Links Nutrient Availability with Inflammation

scientific article published on 14 September 2018

Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

scientific article published on 18 April 2013

Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer

scientific article

mTOR as a central regulator of lifespan and aging

scientific article published on 02 July 2019

miR-137 Modulates a Tumor Suppressor Network-Inducing Senescence in Pancreatic Cancer Cells

scientific article