List of works by Eugenii A. Rabiner

(11)C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than (11)C-( R)-PK11195.

scientific article

117.4 Pet Imaging of Neuroinflammation in Schizophrenia.

scientific article published on 20 March 2017

11C-PBR28 and 18F-PBR111 Detect White Matter Inflammatory Heterogeneity in Multiple Sclerosis

scientific article

5-HT(1A) receptor binding in euthymic bipolar patients using positron emission tomography with [carbonyl-(11)C]WAY-100635.

scientific article published on 2 September 2009

5-Hydroxytryptamine1A receptor occupancy by novel full antagonist 2-[4-[4-(7-chloro-2,3-dihydro-1,4-benzdioxyn-5-yl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3-(2H)-one-1,1-dioxide: a[11C][O-methyl-3H]-N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N

scientific article published in June 2002

A database of [(11)C]WAY-100635 binding to 5-HT(1A) receptors in normal male volunteers: normative data and relationship to methodological, demographic, physiological, and behavioral variables

scientific article (publication date: March 2002)

A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans

scientific article

A graphical method to compare the in vivo binding potential of PET radioligands in the absence of a reference region: application to [¹¹C]PBR28 and [¹⁸F]PBR111 for TSPO imaging

scientific article

A multi-center randomized proof-of-concept clinical trial applying [¹⁸F]FDG-PET for evaluation of metabolic therapy with rosiglitazone XR in mild to moderate Alzheimer's disease

scientific article published on January 2010

A pharmacokinetic PET study of NK₁ receptor occupancy

scientific article

A pseudo-reference region method applied to measurement of GlyT1 occupancy in human brain using [11C]GSK931145 and PET

Accuracy and reliability of [11C]PBR28 specific binding estimated without the use of a reference region

scientific article published on 27 November 2018

Acute acetate administration increases endogenous opioid levels in the human brain: A [<sup>11</sup>C]carfentanil molecular imaging study

scientific article published on 06 January 2021

Advances in CNS PET: the state-of-the-art for new imaging targets for pathophysiology and drug development

scientific article published on 21 September 2019

Affinity and selectivity of [¹¹C]-(+)-PHNO for the D3 and D2 receptors in the rhesus monkey brain in vivo

scientific article published on 24 February 2012

Altered PDE10A expression detectable early before symptomatic onset in Huntington's disease

scientific article published on 21 July 2015

Amphetamine induced endogenous opioid release in the human brain detected with [¹¹C]carfentanil PET: replication in an independent cohort

scientific article

An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28

scientific article

An evaluation of the brain distribution of [(11)C]GSK1034702, a muscarinic-1 (M 1) positive allosteric modulator in the living human brain using positron emission tomography

scientific article published on 5 December 2014

Association between serotonin transporter binding, physiological and environmental factors in healthy male subjects

scholarly article by Robert A. Comley et al published August 2010 in NeuroImage

Awake nonhuman primate brain PET imaging with minimal head restraint: evaluation of GABAA-benzodiazepine binding with 11C-flumazenil in awake and anesthetized animals

scientific article published on 10 October 2013

BRAIN SEROTONIN RELEASE IS REDUCED IN PATIENTS WITH DEPRESSION: A [11C]Cimbi-36 PET STUDY WITH A D-AMPHETAMINE CHALLENGE.

scientific article published in October 2022

Biodistribution and radiation dosimetry of the serotonin 5-HT₆ ligand [¹¹C]GSK215083 determined from human whole-body PET.

scientific article published in August 2012

Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO).

scientific article published on 12 August 2013

Blunted Endogenous Opioid Release Following an Oral Amphetamine Challenge in Pathological Gamblers

scientific article published on 10 November 2015

Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals

scientific article published on 25 June 2018

Brain 5-HT1A receptor binding in chronic fatigue syndrome measured using positron emission tomography and [11C]WAY-100635.

scientific article published in February 2005

Brain Serotonin1A Receptor Binding Measured by Positron Emission Tomography With [11C]WAY-100635

scientific article (publication date: February 2000)

Cerebral serotonin transporter measurements with [11C]DASB: A review on acquisition and preprocessing across 21 PET centres.

scientific article published in January 2018

Characterising the plasma-target occupancy relationship of the neurokinin antagonist GSK1144814 with PET.

scientific article

Characterization of 3 PET Tracers for Quantification of Mitochondrial and Synaptic Function in Healthy Human Brain: 18F-BCPP-EF, 11C-SA-4503, and 11C-UCB-J

scientific article published on 19 July 2019

Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [11C] P943: a positron emission tomography study in Papio anubis

scientific article published on 19 May 2011

Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios

scientific article published on 16 October 2017

Comparison of phosphodiesterase 10A and dopamine transporter levels as markers of disease burden in early Parkinson's disease

scientific article published on 03 June 2019

Connectivity-based functional analysis of dopamine release in the striatum using diffusion-weighted MRI and positron emission tomography ⬇️

scientific article published on 02 January 2013

DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats

scientific article published on 21 January 2020

Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study

scientific article

Determination of [11C]PBR28 binding potential in vivo: a first human TSPO blocking study.

scientific article published in July 2014

Disease-related patterns of in vivo pathology in Corticobasal syndrome

scientific article published on 08 August 2018

Does cannabis affect dopaminergic signaling in the human brain? A systematic review of evidence to date

scientific article published on 30 March 2015

Dopamine (D2/3) receptor agonist positron emission tomography radiotracer [11C]-(+)-PHNO is a D3 receptor preferring agonist in vivo

scientific article published in December 2006

Dopamine D3 receptor ligands for drug addiction treatment: update on recent findings

scientific article published on January 2014

Dynamic, adaptive changes in MAO-A binding after alterations in substrate availability: an in vivo [(11)C]-harmine positron emission tomography study

scientific article published on 21 December 2011

Endogenous opioid release in the human brain reward system induced by acute amphetamine administration

scientific article

Evaluation of 11C-BU99008, a positron emission tomography ligand for the Imidazoline2 binding site in human brain.

scientific article published on 9 March 2018

Evaluation of 11C-GSK189254 as a novel radioligand for the H3 receptor in humans using PET.

scientific article published on 16 June 2010

Evaluation of EMD 128 130 occupancy of the 5-HT1A and the D2 receptor: a human PET study with [11C]WAY-100635 and [11C]raclopride

scientific article

Evaluation of dopamine D₂/₃ specific binding in the cerebellum for the positron emission tomography radiotracer [¹¹C]FLB 457: implications for measuring cortical dopamine release

scientific article

Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands

scientific article

Evidence for GABA-A receptor dysregulation in gambling disorder: correlation with impulsivity

scientific article published on 13 October 2016

Evidence of Brain Inflammation in Patients with Human T-Lymphotropic Virus Type 1-Associated Myelopathy (HAM): A Pilot, Multimodal Imaging Study Using 11C-PBR28 PET, MR T1-Weighted, and Diffusion-Weighted Imaging.

scientific article

Fibromyalgia patients show an abnormal dopamine response to pain

scientific article

First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site

scientific article published on 30 July 2018

Full central neurokinin-1 receptor blockade is required for efficacy in depression: evidence from orvepitant clinical studies

scientific article

Further evaluation of [11C]MP-10 as a radiotracer for phosphodiesterase 10A: PET imaging study in rhesus monkeys and brain tissue metabolite analysis

scientific article

Hippocampal Neuroinflammation, Functional Connectivity, and Depressive Symptoms in Multiple Sclerosis.

scientific article published on 05 December 2015

Human Kinetic Modeling of the 5HT6 PET Radioligand 11C-GSK215083 and Its Utility for Determining Occupancy at Both 5HT6 and 5HT2A Receptors by SB742457 as a Potential Therapeutic Mechanism of Action in Alzheimer Disease.

scientific article published on 17 September 2015

Identifying improved TSPO PET imaging probes through biomathematics: the impact of multiple TSPO binding sites in vivo

scientific article published on 10 January 2012

Imaging cortical dopamine D1 receptors using [11C]NNC112 and ketanserin blockade of the 5-HT 2A receptors

scientific article

Imaging dopamine D3 receptors in the human brain with positron emission tomography, [11C]PHNO, and a selective D3 receptor antagonist.

scientific article published on August 2010

Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy

scientific article

Imaging in Central Nervous System Drug Discovery

scientific article published on 28 October 2016

Imaging nicotine- and amphetamine-induced dopamine release in rhesus monkeys with [(11)C]PHNO vs [(11)C]raclopride PET.

scientific article published on 15 October 2013

Imaging of striatal dopamine release elicited with NMDA antagonists: is there anything there to be seen?

scientific article published on May 2007

Imaging technologies in drug development: Anxiety and depression

scientific article published in January 2005

Imaging the D3 receptor in humans in vivo using [11C](+)-PHNO positron emission tomography (PET).

scientific article published on 11 February 2010

Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson's disease: an in vivo11C-BU99008 PET study

scientific article published on 01 October 2019

In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with (18)F-PBR111 PET.

scientific article

In vivo binding of antipsychotics to D3 and D2 receptors: a PET study in baboons with [11C]-(+)-PHNO.

scientific article published on 22 December 2010

In vivo imaging of cerebral dopamine D3 receptors in alcoholism.

scientific article

In vivo occupancy of the 5-HT1A receptor by a novel pan 5-HT1(A/B/D) receptor antagonist, GSK588045, using positron emission tomography.

scientific article published on 2 December 2014

In vivo quantification of regional dopamine-D3 receptor binding potential of (+)-PHNO: Studies in non-human primates and transgenic mice.

scientific article published in September 2009

Investigation of the Brain Biodistribution of the Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitor [18F]GSK2647544 in Healthy Male Subjects

scientific article published on 11 July 2016

Kinetic analysis of drug-target interactions with PET for characterization of pharmacological hysteresis

scientific article published on 6 February 2013

Kinetic analysis of neuroreceptor binding using PET

Kinetic modeling of 11C-SB207145 binding to 5-HT4 receptors in the human brain in vivo

scientific article

Kisspeptin enhances brain responses to olfactory and visual cues of attraction in men

scientific article published on 13 February 2020

Kisspeptin modulates sexual and emotional brain processing in humans

scientific article

Loss of extra-striatal phosphodiesterase 10A expression in early premanifest Huntington's disease gene carriers

scientific article published on 15 July 2016

Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease

scientific article published on 25 July 2015

Loss of phosphodiesterase 4 in Parkinson disease: Relevance to cognitive deficits

scientific article published on 12 July 2017

Mathematical modelling of [¹¹C]-(+)-PHNO human competition studies

scientific article published on 30 November 2012

Measuring drug occupancy in the absence of a reference region: the Lassen plot re-visited

scientific article published on 9 September 2009

Mitochondrial Complex 1, Sigma 1, and Synaptic Vesicle 2A in Early Drug-Naive Parkinson's Disease

scientific article published on 29 April 2020

Mixed-affinity binding in humans with 18-kDa translocator protein ligands

scientific article

Modulations of human resting brain connectivity by kisspeptin enhance sexual and emotional functions

scientific article published on 18 October 2018

Monoamine transporter occupancy of a novel triple reuptake inhibitor in baboons and humans using positron emission tomography.

scientific article

Nalmefene Reduces Reward Anticipation in Alcohol Dependence: An Experimental Functional Magnetic Resonance Imaging Study.

scientific article

Neuroinflammation and its relationship to changes in brain volume and white matter lesions in multiple sclerosis.

scientific article

Neuroinflammation in treated HIV-positive individuals: A TSPO PET study

scientific article published on 24 February 2016

No effect of dopamine depletion on the binding of the high-affinity D 2/3 radiotracer [11C]FLB 457 in the human cortex

scientific article published in December 2010

Novel PET Biomarkers to Disentangle Molecular Pathways across Age-Related Neurodegenerative Diseases

scientific article published on 02 December 2020

O7.6. GABAA RECEPTOR AVAILABILITY IN PATIENTS WITH SCHIZOPHRENIA: A PET STUDY USING [11C]-RO15

OR06-2 Kisspeptin Enhances Brain Processing of Olfactory and Visual Cues of Attraction in Men.

scientific article

Occupancy of agonist drugs at the 5-HT1A receptor

scientific article published in May 2004

Occupancy of brain dopamine D3 receptors and drug craving: a translational approach.

scientific article

Orbitofrontal connectivity with resting-state networks is associated with midbrain dopamine D3 receptor availability

scientific article

PDE10A and ADCY5 mutations linked to molecular and microstructural basal ganglia pathology

scientific article published on 21 October 2018

PET Radioligands for imaging of the PDE10A in human: current status

scientific article published on 10 August 2018

PET neuroimaging: the elephant unpacks his trunk: comment on Cumming: "PET neuroimaging: the white elephant packs his trunk?".

scientific article

PET studies in drug development: Methodological considerations

article

Patterns of Mitochondrial TSPO Binding in Cerebral Small Vessel Disease: An in vivo PET Study With Neuropathological Comparison

scientific article published on 16 October 2020

Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

article

Phosphodiesterase 10A in Schizophrenia: A PET Study Using [(11)C]IMA107.

scientific article

Positron emission tomography imaging of amphetamine-induced dopamine release in the human cortex: a comparative evaluation of the high affinity dopamine D2/3 radiotracers [11C]FLB 457 and [11C]fallypride

scientific article published in June 2009

Positron emission tomography imaging of dopamine D₂/₃ receptors in the human cortex with [¹¹C]FLB 457: reproducibility studies

scientific article

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects.

scientific article published on 21 November 2014

Positron emission tomography molecular imaging for drug development

scientific article

Positron emission tomography quantification of [11C]-harmine binding to monoamine oxidase-A in the human brain

scientific article

Prediction of repeat-dose occupancy from single-dose data: characterisation of the relationship between plasma pharmacokinetics and brain target occupancy

scientific article

Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?

scientific article

Presynaptic 5-HT1A is related to 5-HTT receptor density in the human brain

scientific article

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.

scientific article published on January 2017

Quantification of human brain PDE4 occupancy by GSK356278: A [(11)C](R)-rolipram PET study.

scientific article

Quantification of the specific translocator protein signal of 18F-PBR111 in healthy humans: a genetic polymorphism effect on in vivo binding.

scientific article published on 26 September 2013

Radiation dose estimates for carbon-11-labelled PET tracers

scientific article published on 26 October 2011

Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor.

scientific article published on 5 January 2012

Radiosynthesis and in vivo evaluation of [(11)C]MP-10 as a positron emission tomography radioligand for phosphodiesterase 10A.

scientific article published on 30 March 2011

Reduced mu opioid receptor availability in schizophrenia revealed with [11C]-carfentanil positron emission tomographic Imaging

scientific article published on 03 October 2019

Resting state synchrony in anxiety-related circuits of abstinent alcohol-dependent patients

scientific article published in November 2013

Role of 18F-fluorodeoxyglucose Positron Emission Tomography in the Monitoring of Inflammatory Activity in Crohn's Disease

scientific article published in November 2016

Serotonergic pathology and disease burden in the premotor and motor phase of A53T α-synuclein parkinsonism: a cross-sectional study

scientific article published on 19 June 2019

Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study

scientific article

Serotonin release measured in the human brain: a PET study with [11C]CIMBI-36 and d-amphetamine challenge

scientific article published on 12 November 2019

Sleep problems and hypothalamic dopamine D3 receptor availability in Parkinson disease

scientific article published on 2 November 2016

Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

scientific article published on 14 January 2020

TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis.

scientific article published on 26 October 2017

Test-retest variability and reference region-based quantification of 18F-BCPP-EF for imaging mitochondrial complex I in the human brain

scientific article published on 05 June 2020

The Effects of Kisspeptin on Brain Response to Food Images and Psychometric Parameters of Appetite in Healthy Men

scientific article published on 19 October 2020

The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description

scientific article

The application of positron emission tomography (PET) imaging in CNS drug development

scientific article published on 01 April 2019

The development, past achievements, and future directions of brain PET

scientific article

The gut hormones PYY 3-36 and GLP-1 7-36 amide reduce food intake and modulate brain activity in appetite centers in humans

scientific article published on 13 October 2011

The relationship between synaptic density marker SV2A, glutamate and N-acetyl aspartate levels in healthy volunteers and schizophrenia: a multimodal PET and magnetic resonance spectroscopy brain imaging study

scientific article published on 17 July 2021

The role of phosphodiesterase 4 in excessive daytime sleepiness in Parkinson's disease

scientific article published on 22 February 2019

Thermal Imaging Is a Noninvasive Alternative to PET/CT for Measurement of Brown Adipose Tissue Activity in Humans

scientific article published on 14 September 2017

Translational PET imaging research

scientific article

Translational characterization of [11C]GSK931145, a PET ligand for the glycine transporter type 1.

scientific article published on 12 August 2011

Translocator positron-emission tomography and magnetic resonance spectroscopic imaging of brain glial cell activation in multiple sclerosis.

scientific article published on 30 November 2016

Translocator protein as an imaging marker of macrophage and stromal activation in RA pannus

scientific article published on 4 January 2018

Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation

scientific article

Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans

scientific article published on 31 August 2011

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