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List of works by Franklyn A Howe

(1) H 2D MRSI tissue type analysis of gliomas

scientific article

1H MR spectroscopy of brain tumours and masses

scientific article

A Longitudinal Study of R2* and R2 Magnetic Resonance Imaging Relaxation Rate Measurements in Murine Liver After a Single Administration of 3 Different Iron Oxide-Based Contrast Agents

scientific article published on 01 December 2005

A prototype decision support system for MR spectroscopy-assisted diagnosis of brain tumours.

scientific article

A two-compartment phosphate-doped gel phantom for localized spectroscopy

scientific article published on 01 January 1992

Acute tumor response to ZD6126 assessed by intrinsic susceptibility magnetic resonance imaging.

scientific article published in May 2005

Allosteric activation of the ATPase activity of the Escherichia coli RhlB RNA helicase.

scientific article published on 28 December 2007

An assessment of artefacts in localized and non-localized31P MRS studies of phosphate metabolites and pH in rat tumours

scientific article published on 01 January 1993

An assessment of the effects of sample ischaemia and spinning time on the metabolic profile of brain tumour biopsy specimens as determined by high-resolution magic angle spinning (1)H NMR.

scientific article

An assessment of31P MRS as a method of measuring pH in rat tumours

scientific article published on 01 November 1992

An investigation of human brain tumour lipids by high-resolution magic angle spinning 1H MRS and histological analysis

scientific article

Anosmin-1 contributes to brain tumor malignancy through integrin signal pathways

scientific article published on 20 December 2013

Apparent T(2) relaxation times of lipid and macromolecules: a study of high-grade tumor spectra

scientific article published in January 2008

Application of magnetic resonance neurography in the evaluation of patients with peripheral nerve pathology.

scientific article

Assessment of the direct effects of DDAH I on tumour angiogenesis in vivo.

scientific article published on 2 May 2018

Automated brain tumour detection and segmentation using superpixel-based extremely randomized trees in FLAIR MRI

scientific article published on 20 September 2016

Automated classification of short echo time in in vivo 1H brain tumor spectra: a multicenter study

scientific article published in January 2003

Automated quality control protocol for MR spectra of brain tumors

scientific article published on June 2008

Biomarkers in Painful Symptomatic Knee OA Demonstrate That MRI Assessed Joint Damage and Type II Collagen Degradation Products Are Linked to Disease Progression

scientific article published on 15 October 2019

Brain tumor classification based on long echo proton MRS signals.

scientific article published in May 2004

Brain tumor classification using the diffusion tensor image segmentation (D-SEG) technique

scientific article published on 13 August 2014

Can MRI T1 be used to detect early changes in 5xFAD Alzheimer's mouse brain?

scientific article published on 26 October 2016

Can localised (19)F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response?

scientific article

Classification of brain tumours from MR spectra: the INTERPRET collaboration and its outcomes

scientific article published on 22 December 2015

Classification of brain tumours from MR spectra: the INTERPRET collaboration and its outcomes.

scientific article

Classification of single-voxel 1H spectra of childhood cerebellar tumors using LCModel and whole tissue representations

scientific article published on 10 August 2012

Clinical proton MR spectroscopy in central nervous system disorders

scientific article published in March 2014

Combined use of neuroradiology and 1H-MR spectroscopy may provide an intervention limiting diagnosis of glioblastoma multiforme

scientific article published in November 2010

Compatibility between 3T 1H SV-MRS data and automatic brain tumour diagnosis support systems based on databases of 1.5T 1H SV-MRS spectra.

scientific article

Continuing ischemic damage after acute middle cerebral artery infarction in humans demonstrated by short-echo proton spectroscopy.

scientific article published on June 1995

Correlations between MRS and DTI in cerebral small vessel disease.

scientific article published in August 2006

Correlations between in vivo (1)H MRS and ex vivo (1)H HRMAS metabolite measurements in adult human gliomas

scientific article published in February 2010

Delineation of gliomas using radial metabolite indexing.

scientific article published on 7 July 2014

Detection of elevated glutathione in meningiomas by quantitative in vivo 1H MRS.

scientific article published in April 2003

Development of a decision support system for diagnosis and grading of brain tumours using in vivo magnetic resonance single voxel spectra.

scientific article published in June 2006

Differentiation of metastases from high-grade gliomas using short echo time 1H spectroscopy.

scientific article published in August 2004

Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease.

scientific article published in March 2008

Discrete Wavelet Transform-Based Whole-Spectral and Subspectral Analysis for Improved Brain Tumor Clustering Using Single Voxel MR Spectroscopy.

scientific article

Discrimination between glioblastoma multiforme and solitary metastasis using morphological features derived from the p:q tensor decomposition of diffusion tensor imaging

scientific article published on 26 July 2014

Discrimination of metabolite from lipid and macromolecule resonances in cerebral infarction in humans using short echo proton spectroscopy.

scientific article published in November 1997

Dynamic asymmetry of phosphocreatine concentration and O(2) uptake between the on- and off-transients of moderate- and high-intensity exercise in humans.

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Dynamics of intramuscular 31P-MRS P(i) peak splitting and the slow components of PCr and O2 uptake during exercise.

scientific article published on 30 August 2002

Effect of Gd-DTPA-BMA on choline signals of HT29 tumors detected by in vivo 1H MRS.

scientific article

Effects of Protocalliphora braueri (Diptera: Calliphoridae) parasitism and inclement weather on nestling sage thrashers

scientific article published on January 1, 1992

Effects of dichloroacetate on V̇o2and intramuscular31P metabolite kinetics during high-intensity exercise in humans ⬇️

scientific article published on May 16, 2003

Effects of prior exercise on oxygen uptake and phosphocreatine kinetics during high-intensity knee-extension exercise in humans

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Evaluation and immunohistochemical qualification of carbogen-induced ΔR₂ as a noninvasive imaging biomarker of improved tumor oxygenation.

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Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers

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Functional MRI demonstrates pain perception in hand osteoarthritis has features of central pain processing

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Gadolinium-complexed Aβ-binding contrast agents for MRI diagnosis of Alzheimer's Disease

scientific article published on 20 July 2015

In vivo 31P MR spectral patterns and reproducibility in cancer patients studied in a multi-institutional trial.

scientific article published on June 2006

In vivo 31P magnetic resonance spectroscopy using a needle microcoil

scientific article published in May 2009

In vivo31p mrs: absolute concentrations, signal-to-noise and prior knowledge

scientific article published on 01 April 1995

Incidence and mechanisms of cerebral ischemia after transcatheter aortic valve implantation compared with surgical aortic valve replacement.

scientific article published on 10 January 2015

Incremental Gaussian Discriminant Analysis based on Graybill and Deal weighted combination of estimators for brain tumour diagnosis.

scientific article

Independent component analysis for automated decomposition of in vivo magnetic resonance spectra

scientific article published in October 2003

Intersample fluctuations in phosphocreatine concentration determined by 31P-magnetic resonance spectroscopy and parameter estimation of metabolic responses to exercise in humans

article

Investigating the role of tumour cell derived iNOS on tumour growth and vasculature in vivo using a tetracycline regulated expression system

scientific article published on 12 January 2016

Issues of normal tissue toxicity in patient and animal studies--effect of carbogen breathing in rats after 5-fluorouracil treatment.

scientific article published in January 2001

Linear discriminant analysis of brain tumour (1)H MR spectra: a comparison of classification using whole spectra versus metabolite quantification.

scientific article

Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain

scientific article published on December 2007

MRS quality assessment in a multicentre study on MRS-based classification of brain tumours

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Magnetic resonance imaging techniques for monitoring changes in tumor oxygenation and blood flow.

scientific article published in July 1998

Magnetic resonance neurography

scientific article published in The Lancet

Magnetic resonance neurography of peripheral nerve following experimental crush injury, and correlation with functional deficit.

scientific article

Magnetic resonance neurography of the median nerve

scientific article published on 01 December 1994

Magnetic resonance neurography studies of the median nerve before and after carpal tunnel decompression

scientific article published on 01 June 2002

Manifold Learning in MR spectroscopy using nonlinear dimensionality reduction and unsupervised clustering

scientific article published on 8 September 2014

Measurement of initial N-acetyl aspartate concentration by magnetic resonance spectroscopy and initial infarct volume by MRI predicts outcome in patients with middle cerebral artery territory infarction.

scientific article

Methodological consensus on clinical proton MRS of the brain: Review and recommendations

scientific article published on 28 March 2019

Methodological standardization for a multi-institutional in vivo trial of localized 31P MR spectroscopy in human cancer research. In vitro and normal volunteer studies.

scientific article published in October 2004

Microarray analysis of bone marrow lesions in osteoarthritis demonstrates upregulation of genes implicated in osteochondral turnover, neurogenesis and inflammation.

scientific article published on 13 July 2017

Modification of Tumour Perfusion and Oxygenation Monitored by Gradient Recalled Echo MRI and31P MRS

scientific article published on 01 August 1996

Morphometric model for discrimination between glioblastoma multiforme and solitary metastasis using three-dimensional shape analysis.

scientific article

Multi-centre reproducibility of diffusion MRI parameters for clinical sequences in the brain.

scientific article

Multicentre evaluation of the INTERPRET decision support system 2.0 for brain tumour classification

scientific article published on 18 July 2014

Muscle metabolism and activation heterogeneity by combined 31P chemical shift and T2 imaging, and pulmonary O2 uptake during incremental knee-extensor exercise

scientific article published on 27 June 2013

New insights into the impact of neuro-inflammation in rheumatoid arthritis

scientific article

Noninvasive monitoring of carbogen-induced changes in tumor blood flow and oxygenation by functional magnetic resonance imaging

scientific article published on 01 November 1995

Noninvasive phosphorus magnetic resonance spectroscopic imaging predicts outcome to first-line chemotherapy in newly diagnosed patients with diffuse large B-cell lymphoma

scientific article published on September 2013

OMICS and brain tumour biomarkers.

scientific article published on October 2006

P06SUPRATENTORIAL PNET IN ADULTS: MRI CAN HELP DISTINGUISH FROM GLIOBLASTOMA - DWI IS KEY.

scientific article published in October 2014

Perfusion by Arterial Spin labelling following Single dose Tadalafil In Small vessel disease (PASTIS): study protocol for a randomised controlled trial

scientific article

Proton spectroscopy in vivo.

scientific article published on March 1993

Quality assessment in in vivo NMR spectroscopy: V. Multicentre evaluation of prototype test objects and protocols for performance assessment in small bore MRS equipment

scientific article published on 01 January 1995

Quantitative evaluation of MRI and histological characteristics of the 5xFAD Alzheimer mouse brain.

scientific article published on 15 March 2013

Quantitative magnetic resonance imaging in neuropsychiatric systemic lupus erythematosus.

scientific article

Quasi-diffusion magnetic resonance imaging (QDI): A fast, high b-value diffusion imaging technique

scientific article published on 04 February 2020

Rare Variant of Vastus Medialis Detected in vivo by Ultrasound and Confirmed by High-resolution MRI.

scientific article published on January 2014

Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease

scientific article

Reduced anterior cingulate grey matter volume in painful hand osteoarthritis

scientific article published on 23 June 2018

Relaxation times in paramagnetically doped agarose gels as a function of temperature and ion concentration

scientific article published on 01 May 1988

Rosiglitazone negatively regulates c-Jun N-terminal kinase and toll-like receptor 4 proinflammatory signalling during initiation of experimental aortic aneurysms

scientific article published on 24 August 2012

Rosiglitazone reduces the development and rupture of experimental aortic aneurysms.

scientific article

Serum alpha 2-HS glycoprotein predicts survival in patients with glioblastoma

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Single dose of the antivascular agent, ZD6126 (N-acetylcolchinol-O-phosphate), reduces perfusion for at least 96 hours in the GH3 prolactinoma rat tumor model

scientific article published on March 2004

Supervised learning based multimodal MRI brain tumour segmentation using texture features from supervoxels

scientific article published on 11 January 2018

Susceptibility contrast magnetic resonance imaging determination of fractional tumor blood volume: a noninvasive imaging biomarker of response to the vascular disrupting agent ZD6126.

scientific article

Taurine: a potential marker of apoptosis in gliomas.

scientific article published on 17 February 2009

The Effects of Tumour Blood Flow and Oxygenation Modifiers on Subcutaneous Tumours as Determined by NIRS

scientific article published on 01 January 2005

The Transient Disappearance of Cerebral Infarction on T2Weighted MRI

scientific article published on 01 September 2000

The clinical value of proton magnetic resonance spectroscopy in adult brain tumours.

scientific article

The effect of pregabalin or duloxetine on arthritis pain: a clinical and mechanistic study in people with hand osteoarthritis.

scientific article published on 10 October 2017

The importance of tumor metabolism in cancer prognosis and therapy; pre-clinical studies on rodent tumors with agents that improve tumor oxygenation

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The relationship between white matter brain metabolites and cognition in normal aging: the GENIE study.

scientific article

The response of human tumors to carbogen breathing, monitored by gradient-recalled echo magnetic resonance imaging

scientific article published on 01 October 1997

The value of magnetic resonance spectroscopy in tumour imaging

scientific article published on 07 May 2008

Tissue-type mapping of gliomas.

scientific article published on 25 December 2018

Toward accurate quantification of metabolites, lipids, and macromolecules in HRMAS spectra of human brain tumor biopsies using LCModel

scientific article published in November 2008

Tri-partite complex for axonal transport drug delivery achieves pharmacological effect

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Tumor R2* is a prognostic indicator of acute radiotherapeutic response in rodent tumors

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Tumor vascular architecture and function evaluated by non-invasive susceptibility MRI methods and immunohistochemistry.

scientific article published in April 2003

Tumour response to hypercapnia and hyperoxia monitored by FLOOD magnetic resonance imaging

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Vascular endothelial growth factor enhances angiotensin II-induced aneurysm formation in apolipoprotein E-deficient mice

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Vessel size index magnetic resonance imaging to monitor the effect of antivascular treatment in a rodent tumor model

scientific article published on 5 June 2008

White matter damage on diffusion tensor imaging correlates with age-related cognitive decline.

scientific article published in January 2006

Why Are Cancers Acidic? A Carrier‐Mediated Diffusion Model for H + Transport in the Interstitial Fluid ⬇️

scientific article published on January 1, 2001

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