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List of works by Han-Jung Chae

4-Phenylbutyric acid regulates CCl4-induced acute hepatic dyslipidemia in a mouse model: A mechanism-based PK/PD study.

scientific article published on 3 March 2016

4-phenylbutyric Acid Regulates Collagen Synthesis and Secretion Induced by High Concentrations of Glucose in Human Gingival Fibroblasts ⬇️

scientific article published on December 27, 2011

A pathogenic role for ER stress-induced autophagy and ER chaperone GRP78/BiP in T lymphocyte systemic lupus erythematosus.

scientific article published on 16 December 2014

A phase II clinical trial to investigate the effect of pioglitazone on (18)F-FDG uptake in malignant lesions

scientific article

AB118. Effect of MOTILIPERM in cisplatin administered SD rats.

scientific article

AMPK activation reduces vascular permeability and airway inflammation by regulating HIF/VEGFA pathway in a murine model of toluene diisocyanate-induced asthma.

scientific article

Adrenomedullin inhibits MAPK pathway-dependent rheumatoid synovial fibroblast-mediated osteoclastogenesis by IL-1 and TNF-alpha.

scientific article

An Involvement of Oxidative Stress in Endoplasmic Reticulum Stress and Its Associated Diseases ⬇️

scientific article published on December 24, 2012

An acidic pH environment increases cell death and pro-inflammatory cytokine release in osteoblasts: the involvement of BAX inhibitor-1.

scientific article published on 12 May 2011

An herbal formula, Herbkines, enhances cytokines production from immune cells.

scientific article

Anti-inflammatory activity of Korean folk medicine 'Sabaeksan'.

scientific article

Apoptosis Induced by Manganese on Neuronal SK-N-MC Cell Line: Endoplasmic Reticulum (ER) Stress and Mitochondria Dysfunction.

scientific article published on 20 December 2011

BI-1 enhances Fas-induced cell death through a Na+/H+-associated mechanism

scientific article

Bax Inhibitor-1 regulates hepatic lipid accumulation via ApoB secretion

scientific article published on 14 June 2016

Bax inhibitor 1 increases cell adhesion through actin polymerization: involvement of calcium and actin binding ⬇️

scientific article

Bax inhibitor-1 regulates the expression of P450 2E1 through enhanced lysosome activity

scientific article published on 03 January 2012

Bax inhibitor-1-mediated inhibition of mitochondrial Ca2+ intake regulates mitochondrial permeability transition pore opening and cell death.

scientific article

Bosellia serrata-induced apoptosis is related with ER stress and calcium release

scientific article

Chalcone suppresses tumor growth through NOX4-IRE1α sulfonation-RIDD-miR-23b axis

scientific article published on 06 January 2021

Cheongyeolsaseuptang inhibits production of TNF-alpha, IL-6 and IL-8 as well as NF-kappa B activation in human mast cells.

scientific article

Citrus Peel Extract Ameliorates High-Fat Diet-Induced NAFLD via Activation of AMPK Signaling

scientific article published on 01 March 2020

Compliance with Saliva Collection Protocol in Healthy Volunteers: Strategies for Managing Risk and Errors.

scientific article published on 22 May 2018

Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress.

scientific article published on 26 July 2017

Determination of phenylbutyric acid and its metabolite phenylacetic acid in different tissues of mouse by liquid chromatography with tandem mass spectrometry and its application in drug tissue distribution

scientific article published on 20 July 2012

Development and validation of a highly sensitive LC-MS/MS method for quantification of IC87114 in mice plasma, bronchoalveolar lavage and lung samples: Application to pharmacokinetic study.

scientific article

Doxorubicin- and daunorubicin-induced regulation of Ca2+ and H+ fluxes through human bax inhibitor-1 reconstituted into membranes.

scientific article

ER stress: Autophagy induction, inhibition and selection.

scientific article published on 21 September 2015

Effect of BI-1 on insulin resistance through regulation of CYP2E1.

scientific article published on 31 August 2016

Effect of dang-gui-ji-hwang-yeum on osteoporosis in ovariectomized rats.

scientific article published in January 2004

Effects of chronic mild stress in female bax inhibitor-1-gene knockout mice.

scientific article published on 20 December 2012

Effects of chronic social defeat stress on behavior and choline acetyltransferase, 78-kDa glucose-regulated protein, and CCAAT/enhancer-binding protein (C/EBP) homologous protein in adult mice.

scientific article published on 7 March 2013

Effects of chronic social defeat stress on behaviour, endoplasmic reticulum proteins and choline acetyltransferase in adolescent mice.

scientific article

Endoplasmic Reticulum Stress and Associated ROS

scientific article

Endoplasmic reticulum stress in the regulation of liver diseases: Involvement of Regulated IRE1α and β-dependent decay and miRNA.

scientific article

Eucommia ulmoides Oliver extract, aucubin, and geniposide enhance lysosomal activity to regulate ER stress and hepatic lipid accumulation

scientific article

Eucommia ulmoides cortex, geniposide and aucubin regulate lipotoxicity through the inhibition of lysosomal BAX.

scientific article

Eucommia ulmoides leaf (EUL) extract enhances NO production in ox-LDL-treated human endothelial cells.

scientific article published on 10 November 2017

Evolutionarily conserved cytoprotection provided by Bax Inhibitor-1 homologs from animals, plants, and yeast

scientific article

Expression of TMBIM6 in Cancers: The Involvement of Sp1 and PKC

scientific article published on 11 July 2019

Functional regulation of hepatic cytochrome p450 enzymes by physicochemical properties of phospholipids in biological membranes.

scientific article published on October 2007

Glucose-lowering effect of Gryllus bimaculatus powder on streptozotocin-induced diabetes through the AKT/mTOR pathway

scientific article published on 11 December 2019

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases.

scientific article published on 6 June 2018

Increased RANKL-mediated osteoclastogenesis by interleukin-1β and endoplasmic reticulum stress

scientific article published on 20 June 2014

Inhibition of endoplasmic reticulum stress alleviates lipopolysaccharide-induced lung inflammation through modulation of NF-κB/HIF-1α signaling pathway ⬇️

scientific article published on January 28, 2013

Inhibitory effects of Okbyungpoong-Gamhmi on anaphylactic responses.

scientific article published in April 2005

Intracellular cleavage of osteopontin by caspase-8 modulates hypoxia/reoxygenation cell death through p53.

scientific article published on 19 August 2009

Involvement of endoplasmic reticulum stress in myofibroblastic differentiation of lung fibroblasts.

scientific article published on 18 August 2011

Is transforming growth factor-β signaling activated in human hypertrophied prostate treated by 5-alpha reductase inhibitor?

scientific article

Isolation of two new bioactive sesquiterpene lactone glycosides from the roots of Ixeris dentata

scientific article published on 24 August 2015

Ixeris dentata Extract Increases Salivary Secretion through the Regulation of Endoplasmic Reticulum Stress in a Diabetes-Induced Xerostomia Rat Model.

scientific article

Ixeris dentata and Lactobacillus gasseri Extracts Improve Salivary Secretion Capability in Diabetes-Associated Dry Mouth Rat Model

scientific article published on 07 May 2020

Ixeris dentata decreases ER stress and hepatic lipid accumulation through regulation of ApoB secretion.

scientific article

Ixeris dentata extract regulates salivary secretion through the activation of aquaporin-5 and prevents diabetes-induced xerostomia.

scientific article

Ixeris dentata-induced regulation of amylase synthesis and secretion in glucose-treated human salivary gland cells.

scientific article

Leaf Extract Ameliorates Steatosis Induced by High-fat Diet in Rats by Increasing Lysosomal Function

scientific article published on 18 February 2019

Mammalian dap3 is an essential gene required for mitochondrial homeostasis in vivo and contributing to the extrinsic pathway for apoptosis.

scientific article

Mechanism of the Inhibitory Effects of Eucommia ulmoides Oliv. Cortex Extracts (EUCE) in the CCl 4 -Induced Acute Liver Lipid Accumulation in Rats

scientific article published on 20 August 2013

Mitochondria in relation to cancer metastasis.

scientific article published on December 2012

Mulberry Extract Attenuates Endothelial Dysfunction through the Regulation of Uncoupling Endothelial Nitric Oxide Synthase in High Fat Diet Rats.

scientific article

Novel approach of molecular genetic understanding of iridology: relationship between iris constitution and angiotensin converting enzyme gene polymorphism.

scientific article published in January 2005

Nox4 regulates the eNOS uncoupling process in aging endothelial cells.

scientific article

Ohmyungsamycins promote antimicrobial responses through autophagy activation via AMP-activated protein kinase pathway

scientific article

PI3Kδ contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD-RIG-I-NF-κB axis.

scientific article published on 16 February 2018

Peroxisome proliferator-activated receptor gamma agonist down-regulates IL-17 expression in a murine model of allergic airway inflammation.

scientific article published on 29 July 2009

Polyphenolic Extract of Euphorbia supina Attenuates Manganese-Induced Neurotoxicity by Enhancing Antioxidant Activity through Regulation of ER Stress and ER Stress-Mediated Apoptosis

scientific article published on 30 January 2017

Porcine placenta hydrolysates enhance osteoblast differentiation through their antioxidant activity and effects on ER stress

scientific article

Porcine placenta hydrolysates regulate calcium disturbance in MC3T3-E1 osteoblastic cells

scientific article

Prevalence of insulin resistance and metabolic syndrome in patients with gouty arthritis.

scientific article published on 20 December 2009

Protective effect of Curcuma longa L. extract on CCl4-induced acute hepatic stress

scientific article

Protective effect of MOTILIPERM in varicocele-induced oxidative injury in rat testis by activating phosphorylated inositol requiring kinase 1α (p-IRE1α) and phosphorylated c-Jun N-terminal kinase (p-JNK) pathways.

scientific article published in December 2018

Protective effect of calceolarioside on adriamycin-induced cardiomyocyte toxicity

scientific article published on 9 May 2006

Protective effects of sodium para-amino salicylate on manganese-induced neuronal death: the involvement of reactive oxygen species

scientific article

Protective role of quercetin against manganese-induced injury in the liver, kidney, and lung; and hematological parameters in acute and subchronic rat models

scientific article published on 5 September 2017

Proteomic profiling of differentially expressed proteins from Bax inhibitor-1 knockout and wild type mice.

scientific article

Quercetin inhibits IL-1β-induced proliferation and production of MMPs, COX-2, and PGE2 by rheumatoid synovial fibroblast.

scientific article published on August 2012

Role of BI-1 (TEGT)-mediated ERK1/2 activation in mitochondria-mediated apoptosis and splenomegaly in BI-1 transgenic mice.

scientific article published on 28 January 2012

Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular Physiology, Calcium, ROS Signaling, and Metaflammation

scientific article published on 08 May 2020

Sodium salicylate inhibits expression of COX-2 through suppression of ERK and subsequent NF-kappaB activation in rat ventricular cardiomyocytes.

scientific article published in July 2003

Soybean greatly reduces valproic acid plasma concentrations: a food-drug interaction study

scientific article published on 12 March 2014

Sulforaphane prevents doxorubicin-induced oxidative stress and cell death in rat H9c2 cells

scientific article

TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy and reduces renal dysfunction in a cyclosporine A-induced nephrotoxicity model

scientific article published on 25 August 2015

TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation

scientific article published on 11 August 2020

The antiosteoporotic effects of Cheonggukjang containing vitamin k2 (menaquinone-7) in ovariectomized rats.

scientific article

The effects of 3, 4 or 5 amino salicylic acids on manganese-induced neuronal death: ER stress and mitochondrial complexes.

scientific article published on 6 April 2011

The effects of MOTILIPERM on cisplatin induced testicular toxicity in Sprague-Dawley rats.

scientific article

The immunosuppressive effect of Buchang-tang through inhibition of mitogen-activated protein kinase and nuclear factor activation in MOLT-4 cells.

scientific article

The imprint of salivary secretion in autoimmune disorders and related pathological conditions.

scientific article published on 8 February 2018

The protective role of Bax inhibitor-1 against chronic mild stress through the inhibition of monoamine oxidase A

scientific article

The regulatory mechanism of 4-phenylbutyric acid against ER stress-induced autophagy in human gingival fibroblasts

scientific article published on 01 July 2012

The roles of ER stress and P450 2E1 in CCl(4)-induced steatosis.

scientific article published on 22 June 2011

Transmembrane BAX Inhibitor Motif-6 (TMBIM6) protects against cisplatin-induced testicular toxicity

scientific article published on 4 January 2018

Treatment of eggshell with casein phosphopeptide reduces the severity of ovariectomy-induced bone loss ⬇️

scientific article published on June 24, 2013

Turmeric extract and its active compound, curcumin, protect against chronic CCl4-induced liver damage by enhancing antioxidation

scientific article

What is the role of unripe Rubus coreanus extract on penile erection?

scientific article published on 01 July 2011

β-Cell protection and antidiabetic activities of Crassocephalum crepidioides (Asteraceae) Benth. S. Moore extract against alloxan-induced oxidative stress via regulation of apoptosis and reactive oxygen species (ROS).

scientific article

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