List of works - Anthony J. Cesare

A CPC-shelterin-BTR axis regulates mitotic telomere deprotection

A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis

scientific article published on 29 May 2020

A genomics approach identifies senescence-specific gene expression regulation.

scientific article

A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

scientific article

A three-state model of telomere control over human proliferative boundaries

scientific article

ATR and mTOR regulate F-actin to alter nuclear architecture and repair replication stress

Alternative lengthening of telomeres: models, mechanisms and implications

scientific article

BRG1 promotes transcriptional patterns that are permissive to proliferation in cancer cells

CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle

scientific article published on 13 November 2019

Cell death during crisis is mediated by mitotic telomere deprotection

scientific article

Chromatin mobility and relocation in DNA repair

scientific article published in October 2021

Control of telomere length by a trimming mechanism that involves generation of t-circles

scientific article published on 12 February 2009

Critical Role for Cold Shock Protein YB-1 in Cytokinesis

scientific article published on 01 September 2020

Dephosphorylation of YB-1 is Required for Nuclear Localisation During G2 Phase of the Cell Cycle

scientific article published on 29 January 2020

Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres

scientific article

Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes

scientific article published on 27 December 2019

Five dysfunctional telomeres predict onset of senescence in human cells

scientific article

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia

scientific article

Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly.

scientific article

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

scientific article

MASTL overexpression promotes chromosome instability and metastasis in breast cancer.

scientific article

Malondialdehyde-like material and beta-thromboglobulin plasma levels in patients suffering from transient ischemic attacks.

scientific article

Mitosis, double strand break repair, and telomeres: a view from the end: how telomeres and the DNA damage response cooperate during mitosis to maintain genome stability.

scientific article published on 29 August 2014

Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

scientific article published on 30 November 2020

Phasor histone FLIM-FRET microscopy quantifies spatiotemporal rearrangement of chromatin architecture during the DNA damage response

scientific article published on 27 March 2019

Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles

scientific article

Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore

scientific article published on 29 October 2020

Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection

scientific article published on 17 September 2019

Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection

Replication stress tolerance and management differs between naïve and primed pluripotent cells

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.

scientific article published on 22 November 2009

Synthetic lethality of cytolytic HSV-1 in cancer cells with ATRX and PML deficiency

scientific article published on 14 March 2019

TRF2-independent chromosome end protection during pluripotency

scientific article published on 25 November 2020

Telomerase promotes formation of a telomere protective complex in cancer cells

scientific article published on 02 October 2019

Telomerase-independent maintenance of telomere length in a vertebrate

Telomere Loop Dynamics in Chromosome End Protection

scientific article published on 19 July 2018

Telomere looping in P. sativum (common garden pea)

scientific article published on 01 October 2003

Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain.

scientific article

Telomere uncapping and alternative lengthening of telomeres

scientific article published on 08 December 2007

Telomere-loop dynamics in chromosome end protection

Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops

scientific article

Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination

scientific article

Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis

scientific article published on 01 December 2005

The basic domain of TRF2 directs binding to DNA junctions irrespective of the presence of TTAGGG repeats

scientific article published on 18 October 2006

The mTOR pathway: Implications for DNA replication

scientific article published on 13 April 2019

The telomere deprotection response is functionally distinct from the genomic DNA damage response.

scientific article published on 11 July 2013

Three-dimensional chromatin organisation shapes origin activation and replication fork directionality

Twenty years of t-loops: A case study for the importance of collaboration in molecular biology

scientific article published on 26 June 2020

Visualization of Telomere Integrity and Function In Vitro and In Vivo Using Immunofluorescence Techniques.

scientific article published on July 2015

Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.

scientific article published on February 2007

List of works by Anthony J. Cesare

A CPC-shelterin-BTR axis regulates mitotic telomere deprotection

A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis

A genomics approach identifies senescence-specific gene expression regulation.

A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

A three-state model of telomere control over human proliferative boundaries

ATR and mTOR regulate F-actin to alter nuclear architecture and repair replication stress

Alternative lengthening of telomeres: models, mechanisms and implications

BRG1 promotes transcriptional patterns that are permissive to proliferation in cancer cells

CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle

Cell death during crisis is mediated by mitotic telomere deprotection

Chromatin mobility and relocation in DNA repair

Control of telomere length by a trimming mechanism that involves generation of t-circles

Critical Role for Cold Shock Protein YB-1 in Cytokinesis

Dephosphorylation of YB-1 is Required for Nuclear Localisation During G2 Phase of the Cell Cycle

Disruption of telomere maintenance by depletion of the MRE11/RAD50/NBS1 complex in cells that use alternative lengthening of telomeres

Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes

Five dysfunctional telomeres predict onset of senescence in human cells

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia

Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly.

Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro

MASTL overexpression promotes chromosome instability and metastasis in breast cancer.

Malondialdehyde-like material and beta-thromboglobulin plasma levels in patients suffering from transient ischemic attacks.

Mitosis, double strand break repair, and telomeres: a view from the end: how telomeres and the DNA damage response cooperate during mitosis to maintain genome stability.

Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress

Phasor histone FLIM-FRET microscopy quantifies spatiotemporal rearrangement of chromatin architecture during the DNA damage response

Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circles

Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore

Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection

Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection

Replication stress tolerance and management differs between naïve and primed pluripotent cells

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.

Synthetic lethality of cytolytic HSV-1 in cancer cells with ATRX and PML deficiency

TRF2-independent chromosome end protection during pluripotency

Telomerase promotes formation of a telomere protective complex in cancer cells

Telomerase-independent maintenance of telomere length in a vertebrate

Telomere Loop Dynamics in Chromosome End Protection

Telomere looping in P. sativum (common garden pea)

Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain.

Telomere uncapping and alternative lengthening of telomeres

Telomere-loop dynamics in chromosome end protection

Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops

Telomeric circles are abundant in the stn1-M1 mutant that maintains its telomeres through recombination

Termination factor-mediated DNA loop between termination and initiation sites drives mitochondrial rRNA synthesis

The basic domain of TRF2 directs binding to DNA junctions irrespective of the presence of TTAGGG repeats

The mTOR pathway: Implications for DNA replication

The telomere deprotection response is functionally distinct from the genomic DNA damage response.

Three-dimensional chromatin organisation shapes origin activation and replication fork directionality

Twenty years of t-loops: A case study for the importance of collaboration in molecular biology

Visualization of Telomere Integrity and Function In Vitro and In Vivo Using Immunofluorescence Techniques.

Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.