List of works - Eveline Lescrinier

(D)- and (L)-cyclohexenyl-G, a new class of antiviral agents: synthesis, conformational analysis, molecular modeling, and biological activity

scientific article published in April 2001

3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase.

scientific article

A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics ⬇️

scientific article

A combination of polyunsaturated fatty acid, nonribosomal peptide and polyketide biosynthetic machinery is used to assemble the zeamine antibiotics. ⬇️

scientific article

A short path synthesis of [13C/15N] multilabeled pyrimidine nucleosides starting from glucopyranose nucleosides

scientific article published in March 2003

A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates

scientific article

Alpha-homo-DNA and RNA form a parallel oriented non-A, non-B-type double helical structure.

scientific article published in December 2001

Base pairing involving artificial bases in vitro and in vivo.

scientific article

Base substituted 5'-O-(N-isoleucyl)sulfamoyl nucleoside analogues as potential antibacterial agents.

scientific article

Base−Base Interactions in the Minor Groove of Double-Stranded DNA

ChemInform Abstract: Selection of New Sequence-Selective Unnatural Peptides Binding to Double-Stranded Deoxyribonucleic Acids (dsDNA) by Means of a Gel-Retardation Experiment for Library Analysis

Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside

scientific article

Complete NMR characterization of lychnose from Stellaria media (L.) Vill

article by Mieke Vanhaecke et al published November 2006 in Carbohydrate Research

Contribution of dihydrouridine in folding of the D-arm in tRNA

scientific article

Correction: Base pairing involving artificial bases and

Cyclohexene Nucleic Acids (CeNA): Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA

scientific article published in 2000

Cyclohexenyl nucleic acids: conformationally flexible oligonucleotides

scientific article

Design and synthesis of nucleolipids as possible activated precursors for oligomer formation via intramolecular catalysis: stability study and supramolecular organization

scientific article published on 9 December 2014

Design of Bioactive Peptides from Naturally Occurring -Conotoxin Structures

scientific article

Difference in conformational diversity between nucleic acids with a six-membered 'sugar' unit and natural 'furanose' nucleic acids

scientific article

Dipeptides as leaving group in the enzyme-catalyzed DNA synthesis

scientific article published in December 2012

Discovery of Novel Druggable Sites on Zika Virus NS3 Helicase Using X-ray Crystallography-Based Fragment Screening ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2018

Discovery of a new Mycobacterium tuberculosis thymidylate synthase X inhibitor with a unique inhibition profile

scientific article published on 27 March 2017

Discovery of a new subclass of α-conotoxins in the venom of Conus australis

scientific article

Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium Tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue

scholarly article published 2014

Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue

scientific article

Efficient and Accurate Potential Energy Surfaces of Puckering in Sugar-Modified Nucleosides

scientific article published on 18 May 2021

Emimycin and its nucleoside derivatives: Synthesis and antiviral activity

scientific article published on 7 December 2017

Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials.

scientific article

Homo-N-nucleosides: Incorporation into oligonucleotides and antiviral activity

scientific article published in 1996

Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents

scientific article published on 29 December 2013

Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor

scientific article published on 27 August 2013

Iminodipropionic acid as the leaving group for DNA polymerization by HIV-1 reverse transcriptase.

scientific article

Influence of circular permutations on the structure and stability of a six-fold circular symmetric designer protein

scientific article published on 02 October 2020

Influence of the nucleobase and anchimeric assistance of the carboxyl acid groups in the hydrolysis of amino acid nucleoside phosphoramidates.

scientific article published on 15 December 2011

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish.

scientific article published on 03 August 2017

Isoguanine and 5-methyl-isocytosine bases, in vitro and in vivo

scientific article published on 13 February 2015

Isolation and characterization of a pentasaccharide from Stellaria media.

scientific article

Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo

scientific article published on 23 July 2018

NMR study on the interaction of the conserved CREX 'stem-loop' in the Hepatitis E virus genome with a naphthyridine-based ligand

scientific article published on 12 August 2015

NMR-based conformational analysis of 2',6-disubstituted uridines and antiviral evaluation of new phosphoramidate prodrugs

scientific article

Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity

scientific article

Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication.

scientific article

Propargylated Purine Deoxynucleosides: New Tools for Fluorescence Imaging Strategies

scientific article published on 28 January 2019

RNase H mediated cleavage of RNA by cyclohexene nucleic acid (CeNA).

scientific article published on December 2001

SYNTHESIS OFN6-ALKYLATED ADENOSINE DERIVATIVES

Self-complementary sequence context in mature miRNAs

scientific article published on 25 January 2010

Solution Structure and Conformational Dynamics of Deoxyxylonucleic Acids (dXNA): An Orthogonal Nucleic Acid Candidate

article

Solution structure of a HNA-RNA hybrid

scientific article

Structural Characterization and Biological Evaluation of Small Interfering RNAs Containing Cyclohexenyl Nucleosides

article

Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

scientific article

Structural and binding study of modified siRNAs with the Argonaute 2 PAZ domain by NMR spectroscopy.

scientific article published on 5 January 2011

Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump.

scientific article published on 21 October 2009

Structure Determination of the Top-Loop of the Conserved 3′-Terminal Secondary Structure in the Genome of Flaviviruses

scientific article

Structure of the alpha-homo-DNA:RNA duplex and the function of twist and slide to catalogue nucleic acid duplexes

scientific article

Structure of the pyrimidine-rich internal loop in the poliovirus 3'-UTR: the importance of maintaining pseudo-2-fold symmetry in RNA helices containing two adjacent non-canonical base-pairs

scientific article

Structure-Function Elucidation of a New -Conotoxin, Lo1a, from Conus longurionis

scientific article

Studies on Disaccharide Nucleoside Synthesis. Mechanism of the Formation of Trisaccharide Purine Nucleosides

scientific article published on 01 April 1999

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

scientific article published on 16 October 2020

Synthesis and Biological Evaluation of Pyrrolo[2,1-f][1,2,4]triazine C-Nucleosides with a Ribose, 2'-Deoxyribose, and 2',3'-Dideoxyribose Sugar Moiety

scientific article published on 21 November 2017

Synthesis and Conformational Study of 3-Hydroxy-4-(Hydroxymethyl)-1-Cyclohexanyl Purines and Pyrimidines

article

Synthesis and Properties of O--D-ribofuranosyl-(1″→2′)-guanosine-5″- O-phosphate and Its Derivatives

scholarly article by Ekaterina V. Efimtseva et al published February 2003 in Helvetica Chimica Acta

Synthesis and Properties of Oligonucleotides Containing 2,4-Dihydroxycyclohexyl Nucleosides

scholarly article by Dorothée Bardiot et al published December 2005 in Helvetica Chimica Acta

Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X

scientific article published on 20 February 2019

Synthesis and biological evaluation of 68Ga labeled bis-DOTA-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) as a PET tracer for in vivo visualization of necrosis.

scientific article published on 9 April 2013

Synthesis and biological evaluation of 68Ga-bis-DOTA-PA as a potential agent for positron emission tomography imaging of necrosis.

scientific article published in August 2013

Synthesis and conformational properties of O-beta-D-ribofuranosyl-(1''-2')-guanosine and (adenosine)-5''-phosphate

scientific article published in May 2003

Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis

scientific article published on 9 June 2011

Synthesis and in vitro enzymatic and antiviral evaluation of phosphoramidate d4T derivatives as chain terminators

scientific article

Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine

scientific article published in April 2003

Synthesis and structure-activity relationship studies of 2-(1,3,4-oxadiazole-2(3H)-thione)-3-amino-5-arylthieno[2,3-b]pyridines as inhibitors of DRAK2.

scientific article

Synthesis of Nicotinamide Adenine Dinucleotide (NAD) Analogues with a Sugar Modified Nicotinamide Moiety

Synthesis of a C-Nucleoside Phosphonate by Base-Promoted Epimerization

scientific article published on 01 February 2018

Synthesis of modified peptidoglycan precursor analogues for the inhibition of glycosyltransferase.

scientific article

The biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structure

scientific article

The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif

scientific article published on 31 May 2006

The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase.

scientific article

Xylonucleic acid: synthesis, structure, and orthogonal pairing properties

scientific article published on 14 July 2015

List of works by Eveline Lescrinier

(D)- and (L)-cyclohexenyl-G, a new class of antiviral agents: synthesis, conformational analysis, molecular modeling, and biological activity

3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase.

A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, zeamine-related antibiotics ⬇️

A combination of polyunsaturated fatty acid, nonribosomal peptide and polyketide biosynthetic machinery is used to assemble the zeamine antibiotics. ⬇️

A short path synthesis of [13C/15N] multilabeled pyrimidine nucleosides starting from glucopyranose nucleosides

A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates

Alpha-homo-DNA and RNA form a parallel oriented non-A, non-B-type double helical structure.

Base pairing involving artificial bases in vitro and in vivo.

Base substituted 5'-O-(N-isoleucyl)sulfamoyl nucleoside analogues as potential antibacterial agents.

Base−Base Interactions in the Minor Groove of Double-Stranded DNA

ChemInform Abstract: Selection of New Sequence-Selective Unnatural Peptides Binding to Double-Stranded Deoxyribonucleic Acids (dsDNA) by Means of a Gel-Retardation Experiment for Library Analysis

Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside

Complete NMR characterization of lychnose from Stellaria media (L.) Vill

Contribution of dihydrouridine in folding of the D-arm in tRNA

Correction: Base pairing involving artificial bases and

Cyclohexene Nucleic Acids (CeNA): Serum Stable Oligonucleotides that Activate RNase H and Increase Duplex Stability with Complementary RNA

Cyclohexenyl nucleic acids: conformationally flexible oligonucleotides

Design and synthesis of nucleolipids as possible activated precursors for oligomer formation via intramolecular catalysis: stability study and supramolecular organization

Design of Bioactive Peptides from Naturally Occurring -Conotoxin Structures

Difference in conformational diversity between nucleic acids with a six-membered 'sugar' unit and natural 'furanose' nucleic acids

Dipeptides as leaving group in the enzyme-catalyzed DNA synthesis

Discovery of Novel Druggable Sites on Zika Virus NS3 Helicase Using X-ray Crystallography-Based Fragment Screening ⬇️

Discovery of a new Mycobacterium tuberculosis thymidylate synthase X inhibitor with a unique inhibition profile

Discovery of a new subclass of α-conotoxins in the venom of Conus australis

Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium Tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue

Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue

Efficient and Accurate Potential Energy Surfaces of Puckering in Sugar-Modified Nucleosides

Emimycin and its nucleoside derivatives: Synthesis and antiviral activity

Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials.

Homo-N-nucleosides: Incorporation into oligonucleotides and antiviral activity

Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents

Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor

Iminodipropionic acid as the leaving group for DNA polymerization by HIV-1 reverse transcriptase.

Influence of circular permutations on the structure and stability of a six-fold circular symmetric designer protein

Influence of the nucleobase and anchimeric assistance of the carboxyl acid groups in the hydrolysis of amino acid nucleoside phosphoramidates.

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish.

Isoguanine and 5-methyl-isocytosine bases, in vitro and in vivo

Isolation and characterization of a pentasaccharide from Stellaria media.

Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo

NMR study on the interaction of the conserved CREX 'stem-loop' in the Hepatitis E virus genome with a naphthyridine-based ligand

NMR-based conformational analysis of 2',6-disubstituted uridines and antiviral evaluation of new phosphoramidate prodrugs

Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity

Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication.

Propargylated Purine Deoxynucleosides: New Tools for Fluorescence Imaging Strategies

RNase H mediated cleavage of RNA by cyclohexene nucleic acid (CeNA).

SYNTHESIS OFN6-ALKYLATED ADENOSINE DERIVATIVES

Self-complementary sequence context in mature miRNAs

Solution Structure and Conformational Dynamics of Deoxyxylonucleic Acids (dXNA): An Orthogonal Nucleic Acid Candidate

Solution structure of a HNA-RNA hybrid

Structural Characterization and Biological Evaluation of Small Interfering RNAs Containing Cyclohexenyl Nucleosides

Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

Structural and binding study of modified siRNAs with the Argonaute 2 PAZ domain by NMR spectroscopy.

Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump.

Structure Determination of the Top-Loop of the Conserved 3′-Terminal Secondary Structure in the Genome of Flaviviruses

Structure of the alpha-homo-DNA:RNA duplex and the function of twist and slide to catalogue nucleic acid duplexes

Structure of the pyrimidine-rich internal loop in the poliovirus 3'-UTR: the importance of maintaining pseudo-2-fold symmetry in RNA helices containing two adjacent non-canonical base-pairs

Structure-Function Elucidation of a New -Conotoxin, Lo1a, from Conus longurionis

Studies on Disaccharide Nucleoside Synthesis. Mechanism of the Formation of Trisaccharide Purine Nucleosides

Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

Synthesis and Biological Evaluation of Pyrrolo[2,1-f][1,2,4]triazine C-Nucleosides with a Ribose, 2'-Deoxyribose, and 2',3'-Dideoxyribose Sugar Moiety

Synthesis and Conformational Study of 3-Hydroxy-4-(Hydroxymethyl)-1-Cyclohexanyl Purines and Pyrimidines

Synthesis and Properties of O--D-ribofuranosyl-(1″→2′)-guanosine-5″- O-phosphate and Its Derivatives

Synthesis and Properties of Oligonucleotides Containing 2,4-Dihydroxycyclohexyl Nucleosides

Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X

Synthesis and biological evaluation of 68Ga labeled bis-DOTA-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) as a PET tracer for in vivo visualization of necrosis.

Synthesis and biological evaluation of 68Ga-bis-DOTA-PA as a potential agent for positron emission tomography imaging of necrosis.

Synthesis and conformational properties of O-beta-D-ribofuranosyl-(1''-2')-guanosine and (adenosine)-5''-phosphate

Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis

Synthesis and in vitro enzymatic and antiviral evaluation of phosphoramidate d4T derivatives as chain terminators

Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine

Synthesis and structure-activity relationship studies of 2-(1,3,4-oxadiazole-2(3H)-thione)-3-amino-5-arylthieno[2,3-b]pyridines as inhibitors of DRAK2.

Synthesis of Nicotinamide Adenine Dinucleotide (NAD) Analogues with a Sugar Modified Nicotinamide Moiety

Synthesis of a C-Nucleoside Phosphonate by Base-Promoted Epimerization

Synthesis of modified peptidoglycan precursor analogues for the inhibition of glycosyltransferase.

The biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structure

The naturally occurring N6-threonyl adenine in anticodon loop of Schizosaccharomyces pombe tRNAi causes formation of a unique U-turn motif

The protein phosphatase 2A phosphatase activator is a novel peptidyl-prolyl cis/trans-isomerase.

Xylonucleic acid: synthesis, structure, and orthogonal pairing properties