List of works - Rainer J. Klement

A giant planet around a metal-poor star of extragalactic origin

scientific article

A ketogenic diet exerts beneficial effects on body composition of cancer patients during radiotherapy: An interim analysis of the KETOCOMP study

scientific article published on 21 March 2019

Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma

scientific article published on 12 December 2019

Addressing the controversial role of ketogenic diets in cancer treatment

scientific article published on 29 March 2020

Anti-Tumor Effects of Ketogenic Diets in Mice: A Meta-Analysis.

scientific article

Anti-cancer effects of hyperbaric oxygen therapy in mice: a meta-analysis

scientific article published on 2 August 2024

Anti-tumor effects of ketogenic diets and their synergism with other treatments in mice: Bayesian evidence synthesis of 1755 individual mouse survival data

scientific article published in February 2024

Applicability of the linear-quadratic formalism for modeling local tumor control probability in high dose per fraction stereotactic body radiotherapy for early stage non-small cell lung cancer.

scientific article published on 30 October 2013

Application of Bayesian evidence synthesis to modelling the effect of ketogenic therapy on survival of high grade glioma patients

article

Assessing Changes in the Activity Levels of Breast Cancer Patients During Radiation Therapy

scientific article

Assessing successful completion of calorie restriction studies for the prevention and treatment of cancer

scientific article published on 19 April 2020

A fatal case of Fournier's gangrene during neoadjuvant radiotherapy for rectal cancer

scientific article published on 23 November 2018

Bayes Lines Tool (BLT): a SQL-script for analyzing diagnostic test results with an application to SARS-CoV-2-testing

scientific article published on 16 February 2022

Bayes Lines Tool (BLT): a SQL-script for analyzing diagnostic test results with an application to SARS-CoV-2-testing

scientific article published on 18 June 2021

Bayes Lines Tool (BLT): a SQL-script for analyzing diagnostic test results with an application to SARS-CoV-2-testing

scientific article published on 10 May 2021

Bayes Lines Tool (BLT): a SQL-script for analyzing diagnostic test results with an application to SARS-CoV-2-testing [version 3; peer review: 2 approved]

scientific article published on 01 January 2021

Bayesian Cure Rate Modeling of Local Tumor Control: Evaluation in Stereotactic Body Radiation Therapy for Pulmonary Metastases

scientific article

Beneficial effects of ketogenic diets for cancer patients: a realist review with focus on evidence and confirmation.

scientific article

Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation.

scientific article published on 11 June 2018

Brooke–Spiegler syndrome: radiotherapy as the last resort?

scientific article published on 27 April 2023

Calorie or carbohydrate restriction? The ketogenic diet as another option for supportive cancer treatment.

scientific article published on January 2013

Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R's through dietary manipulation

scientific article published on March 2014

Cancer as a global health crisis with deep evolutionary roots

scientific article published in January 2024

Comment to Impact of postmastectomy radiotherapy on the outcomes of breast cancer patients with T1-2 N1 disease; an individual patient data analysis of three clinical trials

scientific article published on 01 April 2019

Commentary on "Strong adverse prognostic impact of hyperglycemic episodes during adjuvant chemoradiotherapy of glioblastoma multiforme".

scientific article published in March 2015

Commentary: raised c-troponin levels as a sign of myocardial injury after COVID-19 vaccination in healthy individuals are worrying

scholarly article

Comments on "Inhibition of the ketolytic acetyl CoA supply to tumors could be their 'Achilles heel'"

scientific article published on 22 April 2020

Correlating dose variables with local tumor control in stereotactic body radiotherapy for early stage non-small cell lung cancer: A modelling study on 1500 individual treatments

scientific article published on 15 March 2020

Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.

scientific article published on 21 December 2016

Diazoxide for Lowering Insulin Levels in Breast Cancer Patients.

scientific article published on April 2017

Dietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full repertoire against cancer

scientific article

Dose prescription for stereotactic body radiotherapy: general and organ-specific consensus statement from the DEGRO/DGMP Working Group Stereotactic Radiotherapy and Radiosurgery

scientific article published on 12 July 2024

Effects of Viktor Philippi’s Bioenergetic Meditation on Anxiety, Burnout, and Depression: An Analysis of Four Feasibility Studies

scientific article published on 16 December 2022

Emergence and Evidence: A Close Look at Bunge’s Philosophy of Medicine

scholarly article

Estimation of the α/β ratio of non-small cell lung cancer treated with stereotactic body radiotherapy

scientific article published on 17 August 2019

External validation of a prognostic score predicting overall survival for patients with brain metastases based on extracranial factors

scientific article published on 27 February 2019

Face masks in radiation oncology clinics: based on evidence or source of mistakes?

scientific article published on 01 August 2020

Fasting, Fats, and Physics: Combining Ketogenic and Radiation Therapy against Cancer

scientific article published on 09 November 2017

Feasibility and metabolic effects of a 5:2 fasting intervention in women with breast cancer during radiotherapy

scientific article published on 16 October 2023

Fortifying the Treatment of Prostate Cancer with Physical Activity

scientific article

Impact of Different Types of Diet on Gut Microbiota Profiles and Cancer Prevention and Treatment

scientific article published on 29 March 2019

Impact of a ketogenic diet intervention during radiotherapy on body composition: I. Initial clinical experience with six prospectively studied patients

scientific article

Impact of a ketogenic diet intervention during radiotherapy on body composition: II. Protocol of a randomised phase I study (KETOCOMP).

scientific article published on 15 January 2016

Impact of a ketogenic diet intervention during radiotherapy on body composition: III-final results of the KETOCOMP study for breast cancer patients

scientific article published on 20 August 2020

Impact of a ketogenic diet intervention during radiotherapy on body composition: V. Final results of the KETOCOMP study for head and neck cancer patients

scientific article published on 2 May 2022

In Regard to Britton et al

In Regard to Ohri et al

scientific article published on 20 November 2019

Is there a role for carbohydrate restriction in the treatment and prevention of cancer?

scientific article

Ketogenic diets in medical oncology: a systematic review with focus on clinical outcomes

scientific article published on 11 January 2020

Lack of a dose-effect relationship for pulmonary function changes after stereotactic body radiation therapy for early-stage non-small cell lung cancer

scientific article published on 12 November 2012

Local tumor control probability modeling of primary and secondary lung tumors in stereotactic body radiotherapy

scientific article published on 15 September 2015

Low Vitamin D Status in a Cancer Patient Population from Franconia, Germany

scientific article published on 14 December 2020

Medicine, Money, and Media: A Case Study of How the Covid-19 Crisis Corrupts Disclosure and Publishing Ethics

scientific article published on 9 April 2024

Metabolic factors associated with the prognosis of oligometastatic patients treated with stereotactic body radiotherapy

scientific article published in June 2023

Mimicking caloric restriction: what about macronutrient manipulation? A response to Meynet and Ricci

scientific article published on 21 July 2014

Need for new review of article on ketogenic dietary regimes for cancer patients.

scientific article published on 27 April 2017

Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention.

scientific article

Prediction of Early Death in Patients with Early-Stage NSCLC-Can We Select Patients without a Potential Benefit of SBRT as a Curative Treatment Approach?

scientific article

Problems associated with a highly artificial ketogenic diet: Letter to the Editor Re: van der Louw EJTM, Olieman JF, van den Bemt PMLA, et al. 'Ketogenic diet treatment as adjuvant to standard treatment of glioblastoma multiforme: a feasibility and

scientific article published on 14 October 2019

Radiobiological parameters of liver and lung metastases derived from tumor control data of 3719 metastases

scientific article

Restricting carbohydrates to fight head and neck cancer-is this realistic?

scientific article

Risk factors for vertebral compression fracture after spine stereotactic body radiation therapy: Long-term results of a prospective phase 2 study

scientific article published on 13 September 2019

Short-term effects of a Paleolithic lifestyle intervention in breast cancer patients undergoing radiotherapy: a pilot and feasibility study

scientific article published on 28 November 2020

Stereotactic body radiotherapy (SBRT) for multiple pulmonary oligometastases: Analysis of number and timing of repeat SBRT as impact factors on treatment safety and efficacy.

scientific article published on 3 March 2018

Stereotactic body radiotherapy for oligo-metastatic liver disease - Influence of pre-treatment chemotherapy and histology on local tumor control

scientific article

Support vector machine-based prediction of local tumor control after stereotactic body radiation therapy for early-stage non-small cell lung cancer

scientific article

Systems Thinking About SARS-CoV-2

scientific article published on 28 October 2020

TKTL1 expression in human malign and benign cell lines.

scientific article published on 10 June 2015

The Epistemology of a Positive SARS-CoV-2 Test

scientific article published on 04 September 2020

The Impact of Serum Glucose in the Treatment of Locoregionally Advanced Pancreatic Cancer

scientific article published on 01 September 2019

The Impact of Serum Glucose, Anti-Diabetic Agents, and Statin Usage in Non-small Cell Lung Cancer Patients Treated With Definitive Chemoradiation.

scientific article published on 27 July 2018

The SARS-CoV-2 Crisis: Has Medicine Finally Entered a Reductionist Era?

scientific article published on 04 August 2020

The SARS-CoV-2 crisis: A crisis of reductionism?

scientific article published on 12 June 2020

The SBRT database initiative of the German Society for Radiation Oncology (DEGRO): patterns of care and outcome analysis of stereotactic body radiotherapy (SBRT) for liver oligometastases in 474 patients with 623 metastases.

scientific article published on 13 March 2018

The Safety of COVID-19 Vaccinations—We Should Rethink the Policy

opinion paper

The emerging role of ketogenic diets in cancer treatment

scientific article published on 01 March 2019

The impact of local control on overall survival after stereotactic body radiotherapy for liver and lung metastases from colorectal cancer: a combined analysis of 388 patients with 500 metastases

scientific article published on 26 February 2019

The inflammation paradox: Why are Tsimane protected against Western diseases while Westerners are not?

scientific article published on 01 March 2018

The influence of ketogenic therapy on the 5 R's of radiobiology.

scientific article published on 14 September 2017

The optimal amino acid pattern for humans and its implications for nutrition of cancer patients

scientific article published in July 2024

The photometric classification server for Pan-STARRS1 ⬇️

scientific article published in the Astrophysical Journal

The risk-benefit ratio of Covid-19 vaccines: Publication policy by retraction does nothing to improve it

scientific article published in March 2022

The sedentary (r)evolution: Have we lost our metabolic flexibility?

scientific article

The value of ethnographic studies for making inferences about the nature of the human Paleolithic diet: comments on Lieberman et al. (2023)

scientific article published in December 2023

The visitor from an ancient galaxy: A planetary companion around an old, metal-poor red horizontal branch star

Was there a need for high carbohydrate content in Neanderthal diets?

scientific article published on 24 October 2022

When is a Ketogenic Diet Ketogenic? Comment on "Satiating Effect of a Ketogenic Diet and Its Impact on Muscle Improvement and Oxidation State in Multiple Sclerosis Patients, Nutrients 2019, 11, 1156"

scientific article published on 15 August 2019

Why do people consent to receiving SARS-CoV-2 vaccinations? A representative survey in Germany

scientific article published in August 2022

Why do people consent to receiving SARS-CoV2 vaccinations? A Representative Survey in Germany

scientific article published on 3 January 2022

Wilhelm Brünings' forgotten contribution to the metabolic treatment of cancer utilizing hypoglycemia and a very low carbohydrate (ketogenic) diet.

scientific article

[Unjustified recommendations regarding the ketogenic diet]

scientific article published on 01 May 2018

List of works by Rainer J. Klement

A giant planet around a metal-poor star of extragalactic origin

A ketogenic diet exerts beneficial effects on body composition of cancer patients during radiotherapy: An interim analysis of the KETOCOMP study

Accelerated hyperfractionated radiochemotherapy with temozolomide is equivalent to normofractionated radiochemotherapy in a retrospective analysis of patients with glioblastoma

Addressing the controversial role of ketogenic diets in cancer treatment

Anti-Tumor Effects of Ketogenic Diets in Mice: A Meta-Analysis.

Anti-cancer effects of hyperbaric oxygen therapy in mice: a meta-analysis

Anti-tumor effects of ketogenic diets and their synergism with other treatments in mice: Bayesian evidence synthesis of 1755 individual mouse survival data

Applicability of the linear-quadratic formalism for modeling local tumor control probability in high dose per fraction stereotactic body radiotherapy for early stage non-small cell lung cancer.

Application of Bayesian evidence synthesis to modelling the effect of ketogenic therapy on survival of high grade glioma patients

Assessing Changes in the Activity Levels of Breast Cancer Patients During Radiation Therapy

Assessing successful completion of calorie restriction studies for the prevention and treatment of cancer

A fatal case of Fournier's gangrene during neoadjuvant radiotherapy for rectal cancer

Bayes Lines Tool (BLT): a SQL-script for analyzing diagnostic test results with an application to SARS-CoV-2-testing

Bayes Lines Tool (BLT): a SQL-script for analyzing diagnostic test results with an application to SARS-CoV-2-testing

Bayes Lines Tool (BLT): a SQL-script for analyzing diagnostic test results with an application to SARS-CoV-2-testing

Bayes Lines Tool (BLT): a SQL-script for analyzing diagnostic test results with an application to SARS-CoV-2-testing [version 3; peer review: 2 approved]

Bayesian Cure Rate Modeling of Local Tumor Control: Evaluation in Stereotactic Body Radiation Therapy for Pulmonary Metastases

Beneficial effects of ketogenic diets for cancer patients: a realist review with focus on evidence and confirmation.

Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation.

Brooke–Spiegler syndrome: radiotherapy as the last resort?

Calorie or carbohydrate restriction? The ketogenic diet as another option for supportive cancer treatment.

Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R's through dietary manipulation

Cancer as a global health crisis with deep evolutionary roots

Comment to Impact of postmastectomy radiotherapy on the outcomes of breast cancer patients with T1-2 N1 disease; an individual patient data analysis of three clinical trials

Commentary on "Strong adverse prognostic impact of hyperglycemic episodes during adjuvant chemoradiotherapy of glioblastoma multiforme".

Commentary: raised c-troponin levels as a sign of myocardial injury after COVID-19 vaccination in healthy individuals are worrying

Comments on "Inhibition of the ketolytic acetyl CoA supply to tumors could be their 'Achilles heel'"

Correlating dose variables with local tumor control in stereotactic body radiotherapy for early stage non-small cell lung cancer: A modelling study on 1500 individual treatments

Corticosteroids compromise survival in glioblastoma in part through their elevation of blood glucose levels.

Diazoxide for Lowering Insulin Levels in Breast Cancer Patients.

Dietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full repertoire against cancer

Dose prescription for stereotactic body radiotherapy: general and organ-specific consensus statement from the DEGRO/DGMP Working Group Stereotactic Radiotherapy and Radiosurgery

Effects of Viktor Philippi’s Bioenergetic Meditation on Anxiety, Burnout, and Depression: An Analysis of Four Feasibility Studies

Emergence and Evidence: A Close Look at Bunge’s Philosophy of Medicine

Estimation of the α/β ratio of non-small cell lung cancer treated with stereotactic body radiotherapy

External validation of a prognostic score predicting overall survival for patients with brain metastases based on extracranial factors

Face masks in radiation oncology clinics: based on evidence or source of mistakes?

Fasting, Fats, and Physics: Combining Ketogenic and Radiation Therapy against Cancer

Feasibility and metabolic effects of a 5:2 fasting intervention in women with breast cancer during radiotherapy

Fortifying the Treatment of Prostate Cancer with Physical Activity

Impact of Different Types of Diet on Gut Microbiota Profiles and Cancer Prevention and Treatment

Impact of a ketogenic diet intervention during radiotherapy on body composition: I. Initial clinical experience with six prospectively studied patients

Impact of a ketogenic diet intervention during radiotherapy on body composition: II. Protocol of a randomised phase I study (KETOCOMP).

Impact of a ketogenic diet intervention during radiotherapy on body composition: III-final results of the KETOCOMP study for breast cancer patients

Impact of a ketogenic diet intervention during radiotherapy on body composition: V. Final results of the KETOCOMP study for head and neck cancer patients

In Regard to Britton et al

In Regard to Ohri et al

Is there a role for carbohydrate restriction in the treatment and prevention of cancer?

Ketogenic diets in medical oncology: a systematic review with focus on clinical outcomes

Lack of a dose-effect relationship for pulmonary function changes after stereotactic body radiation therapy for early-stage non-small cell lung cancer

Local tumor control probability modeling of primary and secondary lung tumors in stereotactic body radiotherapy

Low Vitamin D Status in a Cancer Patient Population from Franconia, Germany

Medicine, Money, and Media: A Case Study of How the Covid-19 Crisis Corrupts Disclosure and Publishing Ethics

Metabolic factors associated with the prognosis of oligometastatic patients treated with stereotactic body radiotherapy

Mimicking caloric restriction: what about macronutrient manipulation? A response to Meynet and Ricci

Need for new review of article on ketogenic dietary regimes for cancer patients.

Potential Protective Mechanisms of Ketone Bodies in Migraine Prevention.

Prediction of Early Death in Patients with Early-Stage NSCLC-Can We Select Patients without a Potential Benefit of SBRT as a Curative Treatment Approach?

Problems associated with a highly artificial ketogenic diet: Letter to the Editor Re: van der Louw EJTM, Olieman JF, van den Bemt PMLA, et al. 'Ketogenic diet treatment as adjuvant to standard treatment of glioblastoma multiforme: a feasibility and

Radiobiological parameters of liver and lung metastases derived from tumor control data of 3719 metastases

Restricting carbohydrates to fight head and neck cancer-is this realistic?

Risk factors for vertebral compression fracture after spine stereotactic body radiation therapy: Long-term results of a prospective phase 2 study

Short-term effects of a Paleolithic lifestyle intervention in breast cancer patients undergoing radiotherapy: a pilot and feasibility study

Stereotactic body radiotherapy (SBRT) for multiple pulmonary oligometastases: Analysis of number and timing of repeat SBRT as impact factors on treatment safety and efficacy.

Stereotactic body radiotherapy for oligo-metastatic liver disease - Influence of pre-treatment chemotherapy and histology on local tumor control

Support vector machine-based prediction of local tumor control after stereotactic body radiation therapy for early-stage non-small cell lung cancer

Systems Thinking About SARS-CoV-2

TKTL1 expression in human malign and benign cell lines.

The Epistemology of a Positive SARS-CoV-2 Test

The Impact of Serum Glucose in the Treatment of Locoregionally Advanced Pancreatic Cancer

The Impact of Serum Glucose, Anti-Diabetic Agents, and Statin Usage in Non-small Cell Lung Cancer Patients Treated With Definitive Chemoradiation.

The SARS-CoV-2 Crisis: Has Medicine Finally Entered a Reductionist Era?

The SARS-CoV-2 crisis: A crisis of reductionism?

The SBRT database initiative of the German Society for Radiation Oncology (DEGRO): patterns of care and outcome analysis of stereotactic body radiotherapy (SBRT) for liver oligometastases in 474 patients with 623 metastases.

The Safety of COVID-19 Vaccinations—We Should Rethink the Policy

The emerging role of ketogenic diets in cancer treatment

The impact of local control on overall survival after stereotactic body radiotherapy for liver and lung metastases from colorectal cancer: a combined analysis of 388 patients with 500 metastases

The inflammation paradox: Why are Tsimane protected against Western diseases while Westerners are not?

The influence of ketogenic therapy on the 5 R's of radiobiology.