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List of works by Gregory Petsko

"Sleeping beauty": quiescence in Saccharomyces cerevisiae

scientific article

1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development

scientific article

2.4 A resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor

scientific article (publication date: 10 June 2003)

26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity

scientific article

A Faustian bargain

scientific article published on 31 October 2010

A Phenylalanine Clamp Controls Substrate Specificity in the Quorum-Quenching Metallo-γ-lactonase from Bacillus thuringiensis ⬇️

scientific article published on February 20, 2013

A case of the flu ⬇️

scientific article published on February 24, 2012

A christmas carol

scientific article

A comparison between molecular dynamics and X-ray results for dissociated CO in myoglobin

scientific article published in March 1997

A day in the life of a genome biologist in the not-too-distant future

scientific article published on January 2007

A drop in the bucket

scientific article

A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids

scientific article published on February 1995

A harsh climate

scientific article

A matter of life and death

scientific article

A model worth considering?

scientific article published on January 2006

A new recruit for the army of the men of death

scientific article

A novel structural basis for membrane association of a protein: construction of a chimeric soluble mutant of (S)-mandelate dehydrogenase from Pseudomonas putida

scientific article published on December 1993

A piece of the action

scientific article

A preliminary neutron diffraction study of gamma-chymotrypsin

scientific article published on 26 February 2009

A seat at the table

scientific article published on January 2008

A soluble α-synuclein construct forms a dynamic tetramer

scientific article published on 17 October 2011

A structure of sperm whale myoglobin at a nitrogen gas pressure of 145 atmospheres

scientific article

A transport problem?

scientific article published in Nature

A yeast model of FUS/TLS-dependent cytotoxicity

scientific article

AAVrh.10-mediated APOE2 CNS Gene Therapy for APOE4-associated Alzheimer's Disease

scientific article

Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

scientific article published in Nature

Active Site Analysis of the Potential Antimicrobial Target Aspartate Semialdehyde Dehydrogenase ⬇️

scientific article published on December 4, 2001

Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition

scientific article

Activity and structure of the active-site mutants R386Y and R386F of Escherichia coli aspartate aminotransferase

scientific article

Activity of crystalline turkey egg white lysozyme

scientific article published on January 1, 1992

Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins ⬇️

scientific article published on June 23, 1998

Advice and dissent

scientific article published on 24 November 2009

Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1.

scientific article published on 8 June 2015

Amino-aromatic interactions in proteins

scientific article (publication date: 28 July 1986)

An Asilomar moment

scientific article

An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate

scientific article

An idea whose time has gone

scientific article

An introduction to modeling structure from sequence

scientific article published on October 2006

An issue to remember

scientific article published on 29 September 2009

Analogous inhibitors of elastase do not always bind analogously ⬇️

scientific article published on January 1, 1994

Analyzing Molecular Interactions ⬇️

scientific article published on December 1, 2011

Analyzing molecular interactions

scientific article published on May 2003

Anatomy of a conformational change: hinged "lid" motion of the triosephosphate isomerase loop.

scientific article

Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine

scientific article published in March 2004

And the second shall be first

scientific article published on January 2007

And they said it wouldn't last...

scientific article published on 5 May 2010

Apocalypse now?

scientific article (publication date: 2012)

Aromatic-aromatic interaction: a mechanism of protein structure stabilization

scientific article (publication date: 5 July 1985)

Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation

scientific article published on 17 April 2014

Atomic coordinates for triose phosphate isomerase from chicken muscle

scientific article published on September 7, 1976

BIOCHEMISTRY: How Enzymes Work

scientific article published in Science

Bad chemistry

scientific article

Bailing out

scientific article published on 29 October 2011

Banana republic

scientific article

Behind the Movement ⬇️

scientific article published on September 14, 2012

Big science, little science

scientific article

Biodefense versus bioterrorism

scientific article published on September 2008

Biology's structurally sound foundations

scientific article published in Nature

Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein

scientific article published on August 2016

Cavities in proteins: structure of a metmyoglobin-xenon complex solved to 1.9 A.

scientific article

Chemistry and biology

scientific article

Climate change and the integrity of science

scientific article

Cloning, sequencing, and expression in Escherichia coli of the gene encoding a 45-kilodalton protein, elongation factor Tu, from Chlamydia trachomatis serovar F.

scientific article published on February 1994

Color blind

scientific article

Composition analysis of alpha-helices in thermophilic organisms

scientific article published in September 1995

Conformational substates in a protein: structure and dynamics of metmyoglobin at 80 K.

scientific article

Control of oligomeric enzyme thermostability by protein engineering

scientific article

Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

scientific article published on 16 March 2016

Count me out.

scientific article

Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR

scientific article

Crystal Structure of Green Fluorescent Protein Clover and Design of Clover-Based Redox Sensors

scientific article published on 27 December 2017

Crystal structure at 1.8 A resolution of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis

scientific article published on March 2004

Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6

scientific article

Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida, a fumarase class II type cycloisomerase: enzyme evolution in parallel pathways

scientific article

Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT

scientific article

Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase ⬇️

scientific article published on June 1, 1998

Crystal structure of a D-amino acid aminotransferase: how the protein controls stereoselectivity

scientific article

Crystal structure of a ternary complex of Tritrichomonas foetus inosine 5'-monophosphate dehydrogenase: NAD+ orients the active site loop for catalysis

scientific article

Crystal structure of elastase-substrate complex at -- 55 degrees C

scientific article published on September 23, 1976

Crystal structure of rabbit phosphoglucose isomerase, a glycolytic enzyme that moonlights as neuroleukin, autocrine motility factor, and differentiation mediator

scientific article

Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution

scientific article

Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites

scientific article published on 10 October 2016

Crystal structure of the K12M/G15A triosephosphate isomerase double mutant and electrostatic analysis of the active site

scientific article published on March 1994

Crystal structure of the antigen-binding fragment of the murine anti-arsonate monoclonal antibody 36-71 at 2.9-A resolution

scientific article published on January 1990

Crystal structure of the mutant yeast triosephosphate isomerase in which the catalytic base glutamic acid 165 is changed to aspartic acid

scientific article published on March 1994

Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus

scientific article

Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins

scientific article

Crystal structures of L201A mutant of D-amino acid aminotransferase at 2.0 A resolution: implication of the structural role of Leu201 in transamination ⬇️

scientific article published on August 1, 1998

Crystalline ribonuclease A loses function below the dynamical transition at 220 K

scientific article published in Nature

Crystallization and preliminary X-ray studies of the diphtheria Tox repressor from Corynebacterium diphtheriae

scientific article

Crystallization and preliminary crystallographic analysis of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli

scientific article published in November 1992

Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-A resolution: implications for catalysis

scientific article

Crystallographic cryoenzymology and the legacy of Tony Fink

scientific article published on October 2009

Crystallographic studies of the mechanism of xylose isomerase

scientific article

David Phillips (1924-99)

scientific article published in May 1999

David Phillips and the origin of structural enzymology

scientific article

Design by necessity

scientific article

Design, synthesis, and characterization of a potent xylose isomerase inhibitor, D-threonohydroxamic acid, and high-resolution X-ray crystallographic structure of the enzyme-inhibitor complex

scientific article

Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase

scientific article

Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase

scientific article

Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution

scientific article

Diffraction methods for biological macromolecules. Flow cell construction and use.

scientific article

Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: Exploiting the "glass transition" in protein dynamics

scientific article published on 2 November 2006

Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase

scientific article

Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2.

scientific article published on 21 April 2005

Do the math

scientific article published on January 2006

Doctor Dunsel

scientific article

Dog eat dogma

scientific article

Dominoes ⬇️

scientific article published on November 30, 2011

Dual chemistry catalyzed by human acireductone dioxygenase

scientific article published on 5 January 2017

Déjá vu all over again

scientific article published in Nature

Economies of scale

scientific article

Effects of pH and Iminosugar Pharmacological Chaperones on Lysosomal Glycosidase Structure and Stability

scientific article

Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.

scientific article

Eighty years ago

scientific article

Electrophilic catalysis in triosephosphate isomerase: the role of histidine-95

scientific article

Endosomal Traffic Jams Represent a Pathogenic Hub and Therapeutic Target in Alzheimer's Disease

scientific article published in October 2017

Enzyme evolution. Design by necessity

scientific article published in Nature

Every dog has his day in court ⬇️

scientific article published on November 30, 2010

Everything I need to know about genomics, I learned from Yogi Berra

scientific article published in 2003

Evidence of the Participation of Remote Residues in the Catalytic Activity of Co-Type Nitrile Hydratase from Pseudomonas putida

scientific article

Evolution of an enzyme active site: The structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase ⬇️

scientific article published on September 1, 1998

Expression, crystallization and preliminary crystallographic analysis of human carbonyl reductase

scientific article published in December 1994

Facts and figures

scientific article published on January 2006

Fame is a bubble, but not for some

scientific article

Feet in mouth disease

scientific article

Fish tale

scientific article

Fishing in Src-infested waters

scientific article published in Nature

Fluctuations in Protein Structure from X-Ray Diffraction ⬇️

scientific article published on January 1, 1984

Fly's time.

scientific article published on 29 September 2006

Food of the dogs

scientific article published on 25 July 2011

For medicinal purposes

scientific article

For the good of the state

scientific article

Foxes and hounds

scientific article

From sequence to consequence

scientific article

Funky, not junky

scientific article

Galactose Mutarotase: pH Dependence of Enzymatic Mutarotation ⬇️

scientific article published on April 22, 2003

Galileo's stepchildren

scientific article

Going to the dogs

scientific article

Good chemistry

scientific article

Goodbye, Columbus

scientific article published on January 2012

Grain of truth

scientific article

Gregory Petsko: The coming neurological epidemic

TED2008

Guilt by association

scientific article published on 29 April 2009

H5N1.

scientific article

Half right

scientific article

Hand-made biology

scientific article published on 30 June 2010

Having an impact (factor). ⬇️

scientific article published on 29 July 2008

Heavy metal revival

scientific article published in Nature

Hell is a karaoke cruise

scientific article published on 31 August 2001

High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3

scientific article published in Scientific Reports

Homologuephobia

scientific article

How may you help me?

scientific article

Hydrogen Bond Coupling in the Ketosteroid Isomerase Active Site

scientific article

Hypothesis-driven genomics pays off

scientific article

If you can't take any more of this, please press two

scientific article

In praise of model organisms ⬇️

scientific article published on May 30, 2011

Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms"

scientific article

Inconvenient truths.

scientific article published on 31 May 2007

Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis

scientific article

Instructions for repair

scientific article

Interaction of a Peptidomimetic Aminimide Inhibitor with Elastase ⬇️

scientific article published on July 7, 1995

Intrinsic motions along an enzymatic reaction trajectory

scientific article

Ira

scientific article

Isotopic exchange plus substrate and inhibition kinetics of D-xylose isomerase do not support a proton-transfer mechanism

scientific article published on February 1994

It can't happen here--can it?

scientific article published in January 2007

It is alive

scientific article published on 23 June 2008

Judgement call

scientific article

Kinetic, spectroscopic, and X-ray crystallographic characterization of the functional E151H aminopeptidase from Aeromonas proteolytica.

scientific article published in September 2005

Large cast, but no plot

scientific article published in Nature

Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model

scientific article published on 31 July 2012

Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain ⬇️

scientific article published on August 7, 2012

Let's get our priorities straight

scientific article published in February 2006

Life is a Ponzi scheme

scientific article published on 27 January 2009

Live and let diet

scientific article

Location, location, location

scientific article

Malonate: a versatile cryoprotectant and stabilizing solution for salt-grown macromolecular crystals

scientific article

Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous

scientific article published in Nature

Many happy returns

scientific article published on 27 February 2009

Mapping protein dynamics by X-ray diffraction

scientific article

Mass spectrometry tools for analysis of intermolecular interactions

scientific article

Max in three dimensions

scientific article published in Nature

Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures

scientific article

Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 2. Substrate modeling and active site mutations

scientific article

Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues

scientific article

Mechanism of the reaction catalyzed by mandelate racemase: importance of electrophilic catalysis by glutamic acid 317

scientific article

Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the D270N mutant

scientific article

Mechanism of the reaction catalyzed by mandelate racemase: structure and mechanistic properties of the K166R mutant

scientific article

Mending walls

scientific article

Meta-morphosis

scientific article (publication date: 3 November 2008)

Metal-Dependent Function of a Mammalian Acireductone Dioxygenase

scientific article

Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae

scientific article

Model behavior

scientific article

Molecular dynamics simulations in biology

scientific article

Molecular metamorphosis

scientific article published in Nature

Multiple solvent crystal structures: probing binding sites, plasticity and hydration

scientific article published on 30 January 2006

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

scientific article

My worries are no longer behind me.

scientific article published on January 2007

Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2

scientific article (publication date: May 2014)

New high pH crystal forms of ribonucleases A and S ⬇️

scientific article published on November 1, 1976

No place like Ome

scientific article

No stone unturned

scientific article

Not debatable

scientific article published on 30 April 2008

Nothing to do and all day to do it in

scientific article (publication date: 31 August 2011)

Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease

scientific article published on 29 June 2015

Observation of the light-triggered binding of pyrone to chymotrypsin by Laue x-ray crystallography

scientific article published on July 1991

Observation of unstable species in enzyme-catalyzed transformations using protein crystallography

scientific article

On the origin of enzymatic species

scientific article

On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase ⬇️

scientific article published on June 26, 1981

Open questions: Zombie projects, translational research, and the real secret of the inside of the cell

scientific article

Our own petards

scientific article

Out of Africa

scientific article published on 29 June 2012

PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation

scientific article published on 27 March 2017

Parkinson's Disease and Melanoma: Co-Occurrence and Mechanisms

scholarly article by Anindita Bose et al published 2018 in Journal of Parkinson's disease

Perpetual motion of the worst kind

scientific article

Pharmacogenomics arrives

scientific article

Pharmacological chaperones stabilize retromer to limit APP processing

scientific article

Photolysis and deacylation of inhibited chymotrypsin

scientific article

Polyamine pathway contributes to the pathogenesis of Parkinson disease ⬇️

scientific article published on September 13, 2010

Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage

scientific article published on 26 August 2013

Preliminary X-ray data for a D-amino acid amino-transferase from a novel thermophilic Bacillus

scientific article

Preliminary X-ray data for the ribose binding protein from Salmonella typhimurium

scientific article published on September 1982

Preliminary x-ray data for the galactose binding protein from Salmonella typhimurium

scientific article published on April 1981

Preliminary x-ray data on crystals of mandelate racemase

scientific article

Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis

scientific article

Preserving some sanity ⬇️

scientific article published on January 31, 2011

Probing the Active Center of Benzaldehyde Lyase with Substitutions and the Pseudosubstrate Analogue Benzoylphosphonic Acid Methyl Ester †

scientific article

Protein crystallography at sub-zero temperatures: Cryo-protective mother liquors for protein crystals ⬇️

scientific article published on August 15, 1975

Protein crystallography at sub-zero temperatures: Lysozyme-substrate complexes in cooled mixed solvents ⬇️

scientific article published on August 15, 1975

Protein misfolding and temperature up-shift cause G1 arrest via a common mechanism dependent on heat shock factor in Saccharomycescerevisiae

scientific article

Protein sequencing by computer graphics

scientific article published on April 25, 1977

Proteins at work: "stop-action" pictures at subzero temperatures

scientific article published on January 1984

Proteostasis and Movement Disorders: Parkinson's Disease and Amyotrophic Lateral Sclerosis ⬇️

scientific article published on October 1, 2011

Proton magnetic resonance spectrum of polywater

scientific article

Purification and crystallization of benzoylformate decarboxylase ⬇️

scientific article published on May 1, 1995

Purification, catalytic properties and thermostability of 3-isopropylmalate dehydrogenase from Escherichia coli

scientific article published in January 1997

Purification, crystallization and molecular symmetry of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis

scientific article published on 24 January 2002

Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site

scientific article

Reaction of myoglobin with phenylhydrazine: a molecular doorstop

scientific article published in January 1984

Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy

scientific article published on August 2016

Render unto Darwin

scientific article published on June 2009

Restructuring catalysis in the mandelate pathway

Retromer in Alzheimer disease, Parkinson disease and other neurological disorders

scientific article

Revision of the amino-acid sequence of 3-isopropylmalate dehydrogenase from Salmonella typhimurium by means of X-ray crystallography ⬇️

scientific article published on October 16, 1995

Ribonuclease structure and catalysis: crystal structure of sulfate-free native ribonuclease A at 1.5-A resolution

scientific article published in December 1987

Rising in the East

scientific article

Role of the divalent metal ion in sugar binding, ring opening, and isomerization by D-xylose isomerase: replacement of a catalytic metal by an amino acid

scientific article

Save university arts from the bean counters

scientific article published in December 2010

Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts

scientific article published on 15 August 2013

Second structure determinations

scientific article published in November 1989

Seek and ye shall maybe find

scientific article

Senior moments

scientific article (publication date: 2006)

September 11, 01

scientific article

Sequence and homology model of 3-isopropylmalate dehydrogenase from the psychrotrophic bacterium Vibrio sp. I5 suggest reasons for thermal instability ⬇️

scientific article published on June 1, 1997

Shadows on the wall ⬇️

scientific article published on September 23, 2010

Size doesn't matter

scientific article

Sleeping dogs ⬇️

scientific article published on October 23, 2003

Snapshot of a Reaction Intermediate: Analysis of Benzoylformate Decarboxylase in Complex with a Benzoylphosphonate Inhibitor †

scientific article

Solution of a protein crystal structure with a model obtained from NMR interproton distance restraints

scientific article

Spectroscopic and X-ray crystallographic characterization of bestatin bound to the aminopeptidase from Aeromonas (Vibrio) proteolytica

scientific article

Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer's Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein

scientific article published on 23 February 2018

Still no flying cars

scientific article

Strange days

scientific article

Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis

scientific article

Structural Consequences of Cysteinylation of Cu/Zn-Superoxide Dismutase

scientific article

Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors

scientific article

Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1

scholarly article

Structural basis for differences in substrate selectivity in Kex2 and furin protein convertases

scientific article published in March 2004

Structural dynamics of liganded myoglobin

scientific article

Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion

scientific article

Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c).

scientific article published on 27 March 2017

Structure and activity of two photoreversible cinnamates bound to chymotrypsin

scientific article

Structure and function of snake venom curarimimetic neurotoxins ⬇️

scientific article published on July 1, 1978

Structure and mechanism of benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633, a member of the Class 3 aldehyde dehydrogenase superfamily

scientific article published on 9 March 2017

Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens

scientific article

Structure determination of turkey egg-white lysozyme using Laue diffraction data

scientific article published on April 1, 1992

Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase

scientific article

Structure of a eukaryotic thiaminase I

scientific article

Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease

scientific article

Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis

scientific article

Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5Å resolution: using amino acid sequence data ⬇️

scientific article (publication date: 19 June 1975)

Structure of iron superoxide dismutase from Pseudomonas ovalis at 2.9-A resolution

scientific article published on July 1983

Structure of the Mg(2+)-bound form of CheY and mechanism of phosphoryl transfer in bacterial chemotaxis

scientific article

Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analogue of the intermediate on the reaction pathway

scientific article

Structure of yeast triosephosphate isomerase at 1.9-A resolution

scientific article

Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae

scientific article

Studies of calmodulin structure: laser raman spectroscopy of biomolecules

scientific article published on February 1983

Substrate Inhibition of d-Amino Acid Transaminase and Protection by Salts and by Reduced Nicotinamide Adenine Dinucleotide: Isolation and Initial Characterization of a Pyridoxo Intermediate Related to Inactivation ⬇️

scientific article published on March 3, 1998

Summer reading

scientific article

Sweden has the right idea

scientific article

TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation

scientific article

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

scientific article published on 03 June 2015

Temperature-dependent X-ray diffraction as a probe of protein structural dynamics

scientific article published on August 16, 1979

Testing Geometrical Discrimination within an Enzyme Active Site: Constrained Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole

scientific article

Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole

scientific article

The 'glass transition' in protein dynamics: what it is, why it occurs, and how to exploit it.

scientific article published on September 2003

The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

scientific article

The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with tris: a tale of buffer inhibition

scientific article

The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: A member of the DJ-1/ThiJ/PfpI superfamily

scientific article

The 2.1-A resolution structure of iron superoxide dismutase from Pseudomonas ovalis

scientific article

The 3.0 A crystal structure of xylose isomerase from Streptomyces olivochromogenes

scientific article

The Alrestatin Double-Decker: Binding of Two Inhibitor Molecules to Human Aldose Reductase Reveals a New Specificity Determinant ⬇️

scientific article published on December 23, 1997

The Columnist Manifesto ⬇️

scientific article published on December 28, 2011

The Crystal Structure of Benzoylformate Decarboxylase at 1.6 Å Resolution: Diversity of Catalytic Residues in Thiamin Diphosphate-Dependent Enzymes, ⬇️

scientific article published on July 14, 1998

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

scholarly article

The Rosetta stone

scientific article

The Structural Basis for Pseudoreversion of the E165D Lesion by the Secondary S96P Mutation in Triosephosphate Isomerase Depends on the Positions of Active Site Water Molecules ⬇️

scientific article published on October 17, 1995

The ascent of man?

scientific article

The atomic resolution crystal structure of the YajL (ThiJ) protein from Escherichia coli: a close prokaryotic homologue of the Parkinsonism-associated protein DJ-1.

scientific article published on 2 September 2005

The blue marble ⬇️

scientific article published on April 28, 2011

The catalytic pathway of cytochrome p450cam at atomic resolution

scientific article

The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK)

scientific article

The crystal structure of a post-synaptic neurotoxin from sea snake at A resolution

scientific article published on September 15, 1976

The dark side

scientific article

The devil's in the details

scientific article

The dog days of autumn

scientific article

The dog particle ⬇️

scientific article published on January 30, 2012

The emperor's new shibboleth

scientific article

The evolution of alpha/beta barrel enzymes

scientific article

The father of us all.

scientific article

The grail problem

scientific article published on 9 June 2000

The greatest book you never read

scientific article published on April 2009

The guards themselves

scientific article

The highs and lows of scientific conferences

scientific article published in March 2006

The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase

scientific article

The introduction of specific sites for heavy metal binding in a crystalline protein ⬇️

scientific article published on May 10, 1983

The life aquatic

scientific article

The little Big Bang

scientific article published in Nature

The long and the short of it.

scientific article published on 23 December 2010

The new Manichaeans

scientific article published on 29 May 2008

The next epidemic

scientific article published on 31 May 2006

The ninth wave

scientific article published on January 2006

The one new journal we might actually need

scientific article published on 29 September 2011

The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein

scientific article

The past is a foreign country

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Three-dimensional structure of neurotoxin a from venom of the Philippines sea snake ⬇️

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Time-of-flight neutron diffraction study of bovine γ-chymotrypsin at the Protein Crystallography Station

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Tsunami

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Who steals my identity steals trash.

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Wimps? What wimps?

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X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis

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Xylose isomerase in substrate and inhibitor michaelis states: atomic resolution studies of a metal-mediated hydride shift

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X‐Ray Cryoenzymology ⬇️

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