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List of works by Wendy Thomas

A multiplexed magnetic tweezer with precision particle tracking and bi-directional force control.

scientific article published on 2 December 2017

A structural model for force regulated integrin binding to fibronectin's RGD-synergy site

scientific article published in March 2002

Adaptive mutations in the signal peptide of the type 1 fimbrial adhesin of uropathogenic Escherichia coli

scholarly article

Allosteric coupling in the bacterial adhesive protein FimH

scientific article published on 02 July 2013

Bacterial adhesion to target cells enhanced by shear force

scientific article (publication date: 28 June 2002)

Beyond induced-fit receptor-ligand interactions: structural changes that can significantly extend bond lifetimes

scientific article published in July 2008

Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation

scientific article

Biophysics of catch bonds

scientific article

Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation

scientific article published on 22 February 2019

Catch bond-mediated adhesion without a shear threshold: trimannose versus monomannose interactions with the FimH adhesin of Escherichia coli

scientific article published on 19 April 2006

Catch bonds in adhesion.

scientific article

Catch-bond mechanism of force-enhanced adhesion: counterintuitive, elusive, but ... widespread?

scientific article published on October 2008

Catch-bond model derived from allostery explains force-activated bacterial adhesion

scientific article

Computation of conformational coupling in allosteric proteins

scientific article

Conformational inactivation induces immunogenicity of the receptor-binding pocket of a bacterial adhesin

scientific article

Differential surface activation of the A1 domain of von Willebrand factor

scientific article published on 11 June 2016

Distinctive features of the biological catch bond in the jump-ramp force regime predicted by the two-pathway model

scientific article published on 19 July 2005

Elevated shear stress protects Escherichia coli cells adhering to surfaces via catch bonds from detachment by soluble inhibitors

scientific article

FimH forms catch bonds that are enhanced by mechanical force due to allosteric regulation

scientific article

For catch bonds, it all hinges on the interdomain region: Figure 1.

scientific article (publication date: 21 September 2006)

Inactive conformation enhances binding function in physiological conditions

scientific article

Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli

scientific article published on 14 May 2015

Integrin-like allosteric properties of the catch bond-forming FimH adhesin of Escherichia coli

scientific article published on 3 January 2008

Interdomain interaction in the FimH adhesin of Escherichia coli regulates the affinity to mannose.

scientific article published on 13 June 2007

Mechanism of allosteric propagation across a β-sheet structure investigated by molecular dynamics simulations.

scientific article

Mechanochemistry of receptor-ligand bonds.

scientific article published on 20 January 2009

Only the strong: when antibodies hold on.

scientific article published in February 2018

Recognition of specific sialoglycan structures by oral streptococci impacts the severity of endocardial infection

scientific article published on 24 June 2019

Serine-Rich Repeat Adhesins Mediate Shear-Enhanced Streptococcal Binding to Platelets.

scientific article

Shear Stress Enhances Bacterial Adhesion ⬇️

doctoral thesis by Wendy Evelyn Thomas, University of Washington, 2003

Shear-dependent 'stick-and-roll' adhesion of type 1 fimbriated Escherichia coli

scientific article

Shear-enhanced binding of intestinal colonization factor antigen I of enterotoxigenic Escherichia coli.

scientific article

Shear-stabilized rolling behavior of E. coli examined with simulations.

scientific article

Specific electrostatic interactions between charged amino acid residues regulate binding of von Willebrand factor to blood platelets.

scientific article

Structural basis of type 2A von Willebrand disease investigated by molecular dynamics simulations and experiments

scientific article (publication date: 2012)

The catch bond mechanism between von Willebrand factor and platelet surface receptors investigated by molecular dynamics simulations

scientific article published on 01 August 2010

The cysteine bond in the Escherichia coli FimH adhesin is critical for adhesion under flow conditions

scholarly article by Lina M. Nilsson et al published September 2007 in Molecular Microbiology

Tight Conformational Coupling between the Domains of the Enterotoxigenic Escherichia coli Fimbrial Adhesin CfaE Regulates Binding State Transition

scientific article

Type 1 fimbrial adhesin FimH elicits an immune response that enhances cell adhesion of Escherichia coli

scientific article

Uncoiling mechanics of Escherichia coli type I fimbriae are optimized for catch bonds

scientific article

Weak rolling adhesion enhances bacterial surface colonization

scientific article

Yielding elastic tethers stabilize robust cell adhesion

scientific article (publication date: December 2014)

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