List of works - Miguel Costas

A critical approach to the thermodynamic characterization of inclusion complexes: multiple-temperature isothermal titration calorimetric studies of native cyclodextrins with sodium dodecyl sulfate.

scientific article

A guide to the effects of a large portion of the residues of triosephosphate isomerase on catalysis, stability, druggability, and human disease.

scientific article

A ribosomal misincorporation of Lys for Arg in human triosephosphate isomerase expressed in Escherichia coli gives rise to two protein populations

scientific article

A small molecular size system giving unexpected surface effects: alpha-Cyclodextrin + sodium dodecyl sulfate in water.

scientific article published on 4 September 2008

A strategy based on thermal flexibility to design triosephosphate isomerase proteins with increased or decreased kinetic stability

scientific article published on 22 August 2018

AFFINImeter: A software to analyze molecular recognition processes from experimental data

scientific article published on 05 March 2019

Antimicrobial Peptide against Mycobacterium Tuberculosis That Activates Autophagy Is an Effective Treatment for Tuberculosis

scientific article published on 09 November 2020

Between-species variation in the kinetic stability of TIM proteins linked to solvation-barrier free energies.

scientific article published on 28 October 2008

Complex Behavior of Aqueous α-Cyclodextrin Solutions. Interfacial Morphologies Resulting from Bulk Aggregation.

scientific article published on 23 June 2016

Complexation thermodynamics of α-cyclodextrin with ionic surfactants in water.

scientific article published on 8 June 2017

Correction: Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins

scientific article published on 24 March 2016

Cyclodextrin-based self-assembled nanotubes at the water/air interface.

scientific article published on 17 October 2007

Different contribution of conserved amino acids to the global properties of triosephosphate isomerases

scientific article

Energetic, entropic, and volumetric effects in nonaqueous associated solutions

scientific article

Heat Capacity Contributions to the Formation of Inclusion Complexes

scientific article published on 13 September 2007

Heat capacities of water + organic-solvent mixtures

article

Highly viscoelastic films at the water/air interface: α-Cyclodextrin with anionic surfactants

scientific article published on 23 December 2019

Inactivation of triosephosphate isomerase from Trypanosoma cruzi by an agent that perturbs its dimer interface

scientific article

Insertion of semifluorinated diblocks on DMPC and DPPC liposomes. Influence on the gel and liquid states of the bilayer

scientific article published on 28 April 2010

Interactions between DMPC Liposomes and the Serum Blood Proteins HSA and IgG

article

Interplay between Protein Thermal Flexibility and Kinetic Stability

scientific article

Intrinsic Levanase Activity of Bacillus subtilis 168 Levansucrase (SacB).

scientific article published on 23 November 2015

Isothermal titration calorimetry determination of individual rate constants of trypsin catalytic activity.

scientific article published on 28 March 2015

Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic λ light chain protein

scientific article published on 15 April 2018

Modeling Gibbs energies of solution for a non-polar solute in aqueous solutions of the protein stabilizers glycerol and ethylene glycol.

scientific article published in January 2004

On the characterization of host-guest complexes: surface tension, calorimetry, and molecular dynamics of cyclodextrins with a non-ionic surfactant.

scientific article

Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins

scientific article

Similarities and differences between cyclodextrin-sodium dodecyl sulfate host-guest complexes of different stoichiometries: molecular dynamics simulations at several temperatures.

scientific article

Size product modulation by enzyme concentration reveals two distinct levan elongation mechanisms in Bacillus subtilis levansucrase.

scientific article published on 8 December 2015

Stability and aggregation propensity do not fully account for the association of various germline variable domain gene segments with light chain amyloidosis

scientific article

Structural basis of human triosephosphate isomerase deficiency: mutation E104D is related to alterations of a conserved water network at the dimer interface

scientific article

Structural energetics of protein-carbohydrate interactions: Insights derived from the study of lysozyme binding to its natural saccharide inhibitors.

scientific article

Structural, thermodynamic and catalytic characterization of an ancestral triosephosphate isomerase reveal early evolutionary coupling between monomer association and function

scientific article published on 15 January 2019

Structure and conformational stability of the triosephosphate isomerase from Zea mays. Comparison with the chemical unfolding pathways of other eukaryotic TIMs

scientific article published on 24 September 2018

The effect of specific proline residues on the kinetic stability of the triosephosphate isomerases of two trypanosomes.

scientific article published on 21 December 2016

The influence of non polar and polar molecules in mouse motile cells membranes and pure lipid bilayers

scientific article

The peripheral binding of 14-3-3γ to membranes involves isoform-specific histidine residues

scientific article

The stability and formation of native proteins from unfolded monomers is increased through interactions with unrelated proteins

scientific article

Theoretical analysis of intermolecular interactions of selected residues of triosephosphate isomerase from Trypanosoma cruzi with its inhibitor 3-(2-benzothiazolylthio)-1-propanesulfonic acid.

scientific article published on 8 January 2010

Thermal and chemical unfolding pathways of PaSdsA1 sulfatase, a homo-dimer with topologically interlinked chains

scientific journal article

Thermodynamics of aliphatic and aromatic hydrocarbons in water

scientific article published on 01 August 1998

Thermodynamics of the hydration of non-polar substances

scientific article published on 01 January 1998

Towards an understanding of the heat capacity of liquids. A simple two-state model for molecular association

article

List of works by Miguel Costas

A critical approach to the thermodynamic characterization of inclusion complexes: multiple-temperature isothermal titration calorimetric studies of native cyclodextrins with sodium dodecyl sulfate.

A guide to the effects of a large portion of the residues of triosephosphate isomerase on catalysis, stability, druggability, and human disease.

A ribosomal misincorporation of Lys for Arg in human triosephosphate isomerase expressed in Escherichia coli gives rise to two protein populations

A small molecular size system giving unexpected surface effects: alpha-Cyclodextrin + sodium dodecyl sulfate in water.

A strategy based on thermal flexibility to design triosephosphate isomerase proteins with increased or decreased kinetic stability

AFFINImeter: A software to analyze molecular recognition processes from experimental data

Antimicrobial Peptide against Mycobacterium Tuberculosis That Activates Autophagy Is an Effective Treatment for Tuberculosis

Between-species variation in the kinetic stability of TIM proteins linked to solvation-barrier free energies.

Complex Behavior of Aqueous α-Cyclodextrin Solutions. Interfacial Morphologies Resulting from Bulk Aggregation.

Complexation thermodynamics of α-cyclodextrin with ionic surfactants in water.

Correction: Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins

Cyclodextrin-based self-assembled nanotubes at the water/air interface.

Different contribution of conserved amino acids to the global properties of triosephosphate isomerases

Energetic, entropic, and volumetric effects in nonaqueous associated solutions

Heat Capacity Contributions to the Formation of Inclusion Complexes

Heat capacities of water + organic-solvent mixtures

Highly viscoelastic films at the water/air interface: α-Cyclodextrin with anionic surfactants

Inactivation of triosephosphate isomerase from Trypanosoma cruzi by an agent that perturbs its dimer interface

Insertion of semifluorinated diblocks on DMPC and DPPC liposomes. Influence on the gel and liquid states of the bilayer

Interactions between DMPC Liposomes and the Serum Blood Proteins HSA and IgG

Interplay between Protein Thermal Flexibility and Kinetic Stability

Intrinsic Levanase Activity of Bacillus subtilis 168 Levansucrase (SacB).

Isothermal titration calorimetry determination of individual rate constants of trypsin catalytic activity.

Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic λ light chain protein

Modeling Gibbs energies of solution for a non-polar solute in aqueous solutions of the protein stabilizers glycerol and ethylene glycol.

On the characterization of host-guest complexes: surface tension, calorimetry, and molecular dynamics of cyclodextrins with a non-ionic surfactant.

Reversibility and two state behaviour in the thermal unfolding of oligomeric TIM barrel proteins

Similarities and differences between cyclodextrin-sodium dodecyl sulfate host-guest complexes of different stoichiometries: molecular dynamics simulations at several temperatures.

Size product modulation by enzyme concentration reveals two distinct levan elongation mechanisms in Bacillus subtilis levansucrase.

Stability and aggregation propensity do not fully account for the association of various germline variable domain gene segments with light chain amyloidosis

Structural basis of human triosephosphate isomerase deficiency: mutation E104D is related to alterations of a conserved water network at the dimer interface

Structural energetics of protein-carbohydrate interactions: Insights derived from the study of lysozyme binding to its natural saccharide inhibitors.

Structural, thermodynamic and catalytic characterization of an ancestral triosephosphate isomerase reveal early evolutionary coupling between monomer association and function

Structure and conformational stability of the triosephosphate isomerase from Zea mays. Comparison with the chemical unfolding pathways of other eukaryotic TIMs

The effect of specific proline residues on the kinetic stability of the triosephosphate isomerases of two trypanosomes.

The influence of non polar and polar molecules in mouse motile cells membranes and pure lipid bilayers

The peripheral binding of 14-3-3γ to membranes involves isoform-specific histidine residues

The stability and formation of native proteins from unfolded monomers is increased through interactions with unrelated proteins

Theoretical analysis of intermolecular interactions of selected residues of triosephosphate isomerase from Trypanosoma cruzi with its inhibitor 3-(2-benzothiazolylthio)-1-propanesulfonic acid.

Thermal and chemical unfolding pathways of PaSdsA1 sulfatase, a homo-dimer with topologically interlinked chains

Thermodynamics of aliphatic and aromatic hydrocarbons in water

Thermodynamics of the hydration of non-polar substances

Towards an understanding of the heat capacity of liquids. A simple two-state model for molecular association