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List of works by Yu-Chiang Lai

A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle.

scientific article

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.

scientific article

AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B.

scientific article

Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents.

scientific article published on 25 February 2010

Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

scientific article published on 30 August 2016

Beta-adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA

scientific article

Consumption of carbohydrate solutions enhances energy intake without increased body weight and impaired insulin action in rat skeletal muscles.

scientific article published in April 2005

Effect of insulin and contraction on glycogen synthase phosphorylation and kinetic properties in epitrochlearis muscles from lean and obese Zucker rats

scientific article published on 07 March 2012

Effects of adrenaline on whole-body glucose metabolism and insulin-mediated regulation of glycogen synthase and PKB phosphorylation in human skeletal muscle.

scientific article published on 12 February 2010

Effects of hiking at altitude on body composition and insulin sensitivity in recovering drug addicts.

scientific article published in October 2004

Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle.

scientific article published in November 2014

Glycogen content and contraction regulate glycogen synthase phosphorylation and affinity for UDP-glucose in rat skeletal muscles.

scientific article published on 18 September 2007

Insulin action and signalling in fat and muscle from dexamethasone-treated rats.

scientific article published on 29 February 2008

Insulin-stimulated glycogen synthesis and glycogen synthase activation after electrical stimulation of epitrochlearis muscles with different initial glycogen contents

scientific article published on 01 July 2010

Kinetin Riboside and Its ProTides Activate the Parkinson's Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization

scientific article published on 21 March 2017

Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle

scientific article published on 22 May 2013

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

scientific article published on 01 August 2019

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

scientific article published on October 2013

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.

scientific article published on 15 October 2015

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

scientific article

Regulation of muscle glycogen synthase phosphorylation and kinetic properties by insulin, exercise, adrenaline and role in insulin resistance.

scientific article published on February 2009

The role of dehydroepiandrosterone levels on physiologic acclimatization to chronic mountaineering activity

scientific article published on 01 January 2006

Therapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis

scientific article published on 01 August 2019

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