Search filters

List of works by Tim Skern

100 years poliovirus: from discovery to eradication. A meeting report ⬇️

scientific article published on August 4, 2010

2019: Archives of Virology celebrates its eightieth birthday with a scientific symposium

scientific article published on 17 December 2019

A proposal to change existing virus species names to non-Latinized binomials

scientific article published on 16 October 2010

A structural model of picornavirus leader proteinases based on papain and bleomycin hydrolase

scientific article published on 01 February 1998

Characterization and Structure of the Vaccinia Virus NF-κB Antagonist A46

scientific article

Characterization of the Translation-dependent Step during Iron-regulated Decay of Transferrin Receptor mRNA

scientific article published in Journal of Biological Chemistry

Characterization of the active site thiol group of rhinovirus 2A proteinase.

scientific article published in September 2000

Cleavage of eukaryotic translation initiation factor 4GII within foot-and-mouth disease virus-infected cells: identification of the L-protease cleavage site in vitro

scientific article

Comparison of self-processing of foot-and-mouth disease virus leader proteinase and porcine reproductive and respiratory syndrome virus leader proteinase nsp1α.

scientific article published on 4 June 2013

Crystallization and preliminary X-ray diffraction studies of the Lb proteinase from foot-and-mouth disease virus.

scientific article published on September 1996

Defining residues involved in human rhinovirus 2A proteinase substrate recognition.

scientific article

Denatured virion protein 1 of equine rhinitis B virus 1 contains authentic B-cell epitopes recognised in an enzyme-linked immunosorbent assay--short communication.

scientific article published in June 2008

Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression

scientific article published on 15 July 2020

Editorial

scientific article published on 23 July 2018

Editorial

Equine rhinovirus serotypes 1 and 2: relationship to each other and to aphthoviruses and cardioviruses

scientific article

Eukaryotic initiation factor 4GI is a poor substrate for HIV-1 proteinase

scientific article published on 01 October 2002

Extension of Flavivirus Protein C Differentially Affects Early RNA Synthesis and Growth in Mammalian and Arthropod Host Cells

scientific article

Extremely efficient cleavage of eIF4G by picornaviral proteinases L and 2A in vitro

scientific article published on 01 September 2000

February 1939: the start of the first journal publishing research in virology

scientific article published on 19 March 2019

Foot and mouth disease leader protease (Lbpro): Investigation of prime side specificity allows the synthesis of a potent inhibitor

scientific article published on 06 November 2011

Foot-and-mouth disease virus Lb proteinase can stimulate rhinovirus and enterovirus IRES-driven translation and cleave several proteins of cellular and viral origin.

scientific article published on June 1995

Foot-and-mouth disease virus leader proteinase: structural insights into the mechanism of intermolecular cleavage

scientific article published on 19 September 2014

Generation and genetic stability of tick-borne encephalitis virus mutants dependent on processing by the foot-and-mouth disease virus 3C protease ⬇️

scientific article published on November 30, 2011

How to recognise and deal with dubious virus sequences?

scientific article published on 13 February 2020

Human rhinovirus 2 2Apro recognition of eukaryotic initiation factor 4GI. Involvement of an exosite.

scientific article

Human rhinovirus 2: complete nucleotide sequence and proteolytic processing signals in the capsid protein region.

scientific article published on March 1985

Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GII are different

scientific article

Human rhinovirus 2A proteinase mutant and its second-site revertants.

scientific article published on August 1996

Human rhinovirus mutants resistant to low pH ⬇️

scientific article published on August 1, 1991

Human rhinovirus proteinase 2A induces TH1 and TH2 immunity in patients with chronic obstructive pulmonary disease

scientific article

Human rhinovirus serotype 2: in vitro synthesis of an infectious RNA.

scientific article published in January 1989

ICTV Virus Taxonomy Profile: Picornaviridae

scientific article published on 8 September 2017

Insights into ubiquitin chain architecture using Ub-clipping

scientific article published on 15 August 2019

Interaction of 2A proteinase of human rhinovirus genetic group A with eIF4E is required for eIF4G cleavage during infection.

scientific article

Investigating human immunodeficiency virus-1 proteinase specificity at positions P4 to P2 using a bacterial screening system

scientific article

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

scientific article published on 20 February 2018

L protease from foot and mouth disease virus confers eIF2-independent translation for mRNAs bearing picornavirus IRES.

scientific article published on 28 September 2014

Low cost apparatus for primer-directed DNA amplification using Thermus aquaticus-DNA polymerase

scientific article published on 01 January 1989

Mapping the cleavage site in protein synthesis initiation factor eIF-4 gamma of the 2A proteases from human Coxsackievirus and rhinovirus

scientific article

Model of the equine rhinitis A virus capsid: identification of a major neutralizing immunogenic site

scientific article published in September 2003

Modulation of the electrostatic charge at the active site of foot-and-mouth-disease-virus leader proteinase, an unusual papain-like enzyme.

scientific article published on May 2002

Molecular characterization of a tissue-polypeptide-specific-antigen epitope and its relationship to human cytokeratin 18.

scientific article published on October 1996

Mutational analyses support a model for the HRV2 2A proteinase

scientific article published on 01 August 1997

NMR analysis of the interaction of picornaviral proteinases Lb and 2A with their substrate eukaryotic initiation factor 4GII.

scientific article published on 19 September 2015

NS2B/3 proteolysis at the C-prM junction of the tick-borne encephalitis virus polyprotein is highly membrane dependent

scientific article published on 19 June 2012

New ways of initiating translation in eukaryotes.

scientific article published on December 2001

PCR cloning of a protein-coding part of the thioredoxin gene fromStreptomyces aureofaciens

scientific article published in February 1994

Picornains 2A and 3C.

scientific article

Picornavirus 2A proteinase-mediated stimulation of internal initiation of translation is dependent on enzymatic activity and the cleavage products of cellular proteins

scientific article published on 01 November 1995

Prevalence of neutralizing antibodies to Equine rhinitis A and B virus in horses and man

scientific article (publication date: 10 April 2005)

Protease or protease inhibitor?

scientific article published on 01 March 1990

Proteolytically active 2A proteinase of human rhinovirus 2 is toxic for Saccharomyces cerevisiae but does not cleave the homologues of eIF-4 gamma in vivo or in vitro

scientific article published on 01 June 1996

RNA polymerase-binding sites on the bacterial plasmid pMB9

scientific article published on 01 December 1980

Recognition of eukaryotic initiation factor 4G isoforms by picornaviral proteinases.

scientific article published on 11 September 2002

Recommendations for the nomenclature of enteroviruses and rhinoviruses

scientific article published on 01 March 2020

Relationship of human rhinovirus strain 2 and poliovirus as indicated by comparison of the polymerase gene regions.

scientific article published in July 1984

Rhinoviral receptor discrimination: mutational changes in the canyon regions of human rhinovirus types 2 and 14 indicate a different site of interaction

scientific article published on 01 October 1993

Rhinovirus 2A proteinase mediated stimulation of rhinovirus RNA translation is additive to the stimulation effected by cellular RNA binding proteins

scientific article published on 01 August 1999

Specific cleavage of the nuclear pore complex protein Nup62 by a viral protease

scientific article

Strategies for purifying variants of human rhinovirus 14 2C protein.

scientific article

Structural and biochemical features distinguish the foot-and-mouth disease virus leader proteinase from other papain-like enzymes

scientific article

Structure and dynamics of coxsackievirus B4 2A proteinase, an enyzme involved in the etiology of heart disease

scientific article

Substrate requirements of a human rhinoviral 2A proteinase ⬇️

scientific article published on March 1, 1991

Sulphation of hirudin in BHK cells

scientific article published on 01 November 1990

The 2A proteinase of human rhinovirus is a zinc containing enzyme.

scientific article published in November 1994

The eIF4G-eIF4E complex is the target for direct cleavage by the rhinovirus 2A proteinase.

scientific article

The leader proteinase of foot-and-mouth disease virus: structure-function relationships in a proteolytic virulence factor

scientific article published on October 2014

The structure of the 2A proteinase from a common cold virus: a proteinase responsible for the shut-off of host-cell protein synthesis

scientific article

The structures of picornaviral proteinases.

scientific article

Translation directed by hepatitis A virus IRES in the absence of active eIF4F complex and eIF2

scientific article

Typing of human rhinoviruses based on sequence variations in the 5' non-coding region

scientific article published on 01 November 1989

Using proteinase trapping to detect revertants of inactive rhinoviral 2A proteinase mutants

scientific article published on July 1, 1992

Vaccinia Virus Immunomodulator A46: A Lipid and Protein-Binding Scaffold for Sequestering Host TIR-Domain Proteins

scientific article

Vaccinia virus G1 protein: absence of autocatalytic self-processing.

scientific article published on 18 May 2017

Validation of a structural comparison of the antigenic characteristics of Usutu virus and West Nile virus envelope proteins.

scientific article published on 26 May 2014

Virus species polemics: 14 senior virologists oppose a proposed change to the ICTV definition of virus species

scientific article published on 27 December 2012

elF4G and its proteolytic cleavage products: effect on initiation of protein synthesis from capped, uncapped, and IRES-containing mRNAs.

scientific article published on February 1997

Paulina is supported by:

About Paulina

Help