List of works by Michaela Frye

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

scientific article

Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions

scientific article

Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin

scientific article

Characterizing 5-methylcytosine in the mammalian epitranscriptome

scientific article

Chromatin regulators in mammalian epidermis

scientific article published on September 2012

Codon usage optimization in pluripotent embryonic stem cells.

scientific article published on 7 June 2019

Considerations for skin carcinogenesis experiments using inducible transgenic mouse models.

scientific article

Cytosine-5 RNA Methylation Regulates Neural Stem Cell Differentiation and Motility

scientific article published on 23 December 2016

Cytosine-5 RNA methylation links protein synthesis to cell metabolism

scientific article published on 14 June 2019

Deficient methylation and formylation of mt-tRNA(Met) wobble cytosine in a patient carrying mutations in NSUN3

scientific journal article

Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation

scientific article

Epithelial defensins impair adenoviral infection: implication for adenovirus-mediated gene therapy

scientific article (publication date: 10 April 1999)

Erratum: MYC in mammalian epidermis: how can an oncogene stimulate differentiation? (Erratum)

scholarly article published in Nature Reviews Cancer

Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment

scientific article published on June 2003

Expression of human beta defensin (HBD-1 and HBD-2) mRNA in nasal epithelia of adult cystic fibrosis patients, healthy individuals, and individuals with acute cold.

scientific article published in January 2002

Expression of human beta-defensin-1 promotes differentiation of keratinocytes.

scientific article

Genetically induced cell death in bulge stem cells reveals their redundancy for hair and epidermal regeneration

scientific article published on March 2015

Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer

scientific article

Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis

scientific article published on May 2009

MYC in mammalian epidermis: how can an oncogene stimulate differentiation?

scientific article published on March 2008

Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability

scientific article

Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1

scientific article

NSun2-mediated cytosine-5 methylation of vault noncoding RNA determines its processing into regulatory small RNAs

scientific article

Positioning Europe for the EPITRANSCRIPTOMICS challenge.

scientific article published on 19 April 2018

Post-transcriptional modifications in development and stem cells

scientific article

Posttranscriptional methylation of transfer and ribosomal RNA in stress response pathways, cell differentiation, and cancer

scientific article published on 21 November 2015

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.

scientific article published on 12 August 2012

RNA modifications modulate gene expression during development

scientific article published on 01 September 2018

RNA modifications regulating cell fate in cancer

scientific article published on 02 May 2019

RNA modifications: what have we learned and where are we headed?

scientific article published on 3 May 2016

Regulation of Human Epidermal Stem Cell Proliferation and Senescence Requires Polycomb- Dependent and -Independent Functions of Cbx4

Regulation of human epidermal stem cell proliferation and senescence requires polycomb- dependent and -independent functions of Cbx4.

scientific article published in September 2011

Role of RNA methyltransferases in tissue renewal and pathology

scientific article

Stem cell depletion through epidermal deletion of Rac1.

scientific article

Stem cell function and stress response are controlled by protein synthesis

scientific article published on 15 June 2016

Stem cells in ectodermal development

scientific article published on 09 May 2012

The RNA Methyltransferase Misu (NSun2) Mediates Myc-Induced Proliferation and Is Upregulated in Tumors

The RNA methyltransferase Misu (NSun2) mediates Myc-induced proliferation and is upregulated in tumors

scientific article

The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate

scientific article published on December 2011

The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin

scientific article

The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation

scientific journal article

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability

scientific article

The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis

scientific article published on 20 November 2011

Whole exome sequencing identifies a splicing mutation in NSUN2 as a cause of a Dubowitz-like syndrome

scientific article

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