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List of works by Pedro Casado

A Self-validating Quantitative Mass Spectrometry Method for Assessing the Accuracy of High-content Phosphoproteomic Experiments ⬇️

scientific article published on October 24, 2010

A TRAF2 binding independent region of TNFR2 is responsible for TRAF2 depletion and enhancement of cytotoxicity driven by TNFR1.

scientific article published on January 2014

Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans

scientific article published on 01 April 2021

Approaches for measuring signalling plasticity in the context of resistance to targeted cancer therapies.

scientific article

Bespoken nanoceria: A new effective treatment in experimental hepatocellular carcinoma

scientific article published on 21 January 2020

Cancer associated fibroblast FAK regulates malignant cell metabolism

scientific article published on 10 March 2020

Characterization of HSP27 phosphorylation induced by microtubule interfering agents: implication of p38 signalling pathway.

scientific article published on 16 February 2007

Characterization of a TiO₂ enrichment method for label-free quantitative phosphoproteomics.

scientific article published on 18 February 2011

Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs

scientific article published on 25 March 2021

ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells

scientific article published on 27 May 2015

Effect of vinca alkaloids on ERalpha levels and estradiol-induced responses in MCF-7 cells.

scientific article published on 23 March 2006

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

scientific article published in Nature Communications

Environmental stress affects the activity of metabolic and growth factor signaling networks and induces autophagy markers in MCF7 breast cancer cells

scientific article published on 14 January 2014

Factors Secreted by Cancer-Associated Fibroblasts that Sustain Cancer Stem Properties in Head and Neck Squamous Carcinoma Cells as Potential Therapeutic Targets

scientific article published on 17 September 2018

Global profiling of protein kinase activities in cancer cells by mass spectrometry

scientific article

Impact of phosphoproteomics in the translation of kinase-targeted therapies.

scientific article

Kinase activity ranking using phosphoproteomics data (KARP) quantifies the contribution of protein kinases to the regulation of cell viability.

scientific article

Kinase-substrate enrichment analysis provides insights into the heterogeneity of signaling pathway activation in leukemia cells.

scientific article published on 26 March 2013

Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data

scientific article

Oxidative stress downstream of mTORC1 but not AKT causes a proliferative defect in cancer cells resistant to PI3K inhibition

scientific article published on 19 December 2016

Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance.

scientific article published on 29 April 2012

Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors

scientific article

Phosphorylation of human eukaryotic elongation factor 1Bgamma is regulated by paclitaxel

scientific article

Poly(ADP-Ribose) Polymerase-1 inhibition potentiates cell death and phosphorylation of DNA damage response proteins in oxidative stressed retinal cells

scientific article published on 05 September 2019

Proteomic analysis of annexin A2 phosphorylation induced by microtubule interfering agents and kinesin spindle protein inhibitors

scientific article published in September 2010

Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells.

scientific article published on 7 April 2018

Vincristine regulates the phosphorylation of the antiapoptotic protein HSP27 in breast cancer cells.

scientific article published on 14 July 2006

eEF2K Activity Determines Synergy to Cotreatment of Cancer Cells With PI3K and MEK Inhibitors

scientific article published on 02 May 2022

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