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List of works by Tung-Tien Sun

A 300 bp 5’ -upstream sequence of a differentiation-dependent rabbit K3 keratin gene can serve as a keratinocyte-specific promoter ⬇️

scientific article published on June 1, 1993

A tissue-specific promoter that can drive a foreign gene to express in the suprabasal urothelial cells of transgenic mice.

scientific article

Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux

scientific article

Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux

scientific article published on 01 June 2001

Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins

scientific article

Allelic loss of p53 gene is associated with genesis and maintenance, but not invasion, of mouse carcinoma in situ of the bladder

scientific article published on 01 January 2003

Alterations in bladder function associated with urothelial defects in uroplakin II and IIIa knockout mice.

scientific article

Altered phenotype of cultured urothelial and other stratified epithelial cells: implications for wound healing.

scientific article

Analysis of differentiation-associated proteins in rat bladder carcinogenesis.

scientific article

Analysis of electroblotted proteins by mass spectrometry: protein identification after Western blotting

scientific article

Anatomy and Physiology of the Urinary Tract: Relation to Host Defense and Microbial Infection

scientific article

Antikeratin antibodies in tumor diagnosis. Distinction between seminoma and embryonal carcinoma

scientific article published on 01 September 1984

Appearance of the keratin pair K3/K12 during embryonic and adult corneal epithelial differentiation in the chick and in the rabbit.

scientific article published in December 1990

Assembly of a membrane receptor complex: roles of the uroplakin II prosequence in regulating uroplakin bacterial receptor oligomerization.

scientific article

Assembly of urothelial plaques: tetraspanin function in membrane protein trafficking.

scientific article

Autologous transplantation of urothelium into demucosalized gastrointestinal segments: evidence for epithelialization and differentiation of in vitro expanded and transplanted urothelial cells.

scientific article published on January 1998

Bacteria-induced uroplakin signaling mediates bladder response to infection

scientific article

Bilateral tubal ectopic pregnancy after in vitro fertilization and embryo transfer

scientific article published on 01 October 1991

Brenner tumors but not transitional cell carcinomas of the ovary show urothelial differentiation: immunohistochemical staining of urothelial markers, including cytokeratins and uroplakins

scientific article published on 01 February 2001

Cell culture of mammalian thymic epithelial cells: growth, structural, and antigenic properties.

scientific article published on January 1984

Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles

scientific article published on 01 January 1994

Cellular basis of urothelial squamous metaplasia: roles of lineage heterogeneity and cell replacement

scientific article

Chromosomal localization of uroplakin genes of cattle and mice

article

Clinical, electron microscopic, and monoclonal antibody studies of intraocular epithelial downgrowth

scientific article

Clonal analysis of the in vivo differentiation potential of keratinocytes.

scientific article published on March 1997

Comparison of limbal and conjunctival autograft transplantation in corneal surface reconstruction in rabbits

scientific article published on 01 April 1990

Comparison of uroplakin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats and mice.

scientific article published in November 1999

Control of a Cell Surface Major Glycoprotein by Epidermal Growth Factor ⬇️

scientific article published on August 19, 1977

Cornea-specific expression of K12 keratin during mouse development.

scientific article published on November 1993

Corneal epithelial stem cells: past, present, and future.

scientific article published in September 2004

Correlation of specific keratins with different types of epithelial differentiation: monoclonal antibody studies.

scientific article

Cultured epithelial cells of cornea, conjunctiva and skin: absence of marked intrinsic divergence of their differentiated states ⬇️

scientific article published on October 6, 1977

Cutaneous ultrastructural features of the flaky skin (fsn) mouse mutation.

scientific article

De Novo Uroplakin IIIa Heterozygous Mutations Cause Human Renal Adysplasia Leading to Severe Kidney Failure

scientific article published on 11 May 2005

Deficiency of pRb family proteins and p53 in invasive urothelial tumorigenesis.

scientific article published on December 2009

Detection of circulating cancer cells expressing uroplakins and epidermal growth factor receptor in bladder cancer patients.

scientific article

Detection of circulating uroplakin-positive cells in patients with transitional cell carcinoma of the bladder.

scientific article

Differential expression of cell cycle regulators in phenotypic variants of transgenically induced bladder tumors: implications for tumor behavior

scientific article published on 01 February 2005

Differentiation of the epidermal keratinocyte in cell culture: formation of the cornified envelope

scientific article published on December 1, 1976

Differentiation-dependent expression of keratins in human oral epithelia.

scientific article published on March 1986

Distinct Glycan Structures of Uroplakins Ia and Ib

scientific article published in Journal of Biological Chemistry

Dual ligand/receptor interactions activate urothelial defenses against uropathogenic E. coli

scientific article

Ectopic expression of a bacterial lacZ gene in the limbic system of transgenic mice

scientific article published on 01 August 1995

Epidermal stem cells

scientific article published on 01 July 1983

Epidermal stem cells: properties, markers, and location.

scientific article

Epithelial growth and differentiation: an overview.

scientific article

Epithelial stem cells: the eye provides a vision.

scientific article published on November 2003

Epithelialization of the corneal endothelium in posterior polymorphous dystrophy

scientific article published on 01 July 1980

Evaluation of the American Academy of Dermatology's National Skin Cancer Early Detection and Screening Program.

scientific article published on June 1996

Excessive trust in authorities and its influence on experimental design

scientific article published on 01 July 2004

Expression of K12 keratin in alkali-burned rabbit corneas

scientific article published on September 1, 1992

Expression of hair-related keratins in a soft epithelium: subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of differentiation.

scientific article

Expression of keratin 5 as a distinctive feature of epithelial and biphasic mesotheliomas. An immunohistochemical study using monoclonal antibody AE14.

scientific article

Expression of keratin and vimentin intermediate filaments in rabbit bladder epithelial cells at different stages of benzo[a]pyrene-induced neoplastic progression ⬇️

scientific article published on July 1, 1981

Expression of keratohyalin-trichohyalin hybrid granules in molluscum contagiosum

scientific article published on 01 February 1996

Expression of specific keratin markers by rabbit corneal, conjunctival, and esophageal epithelia during vitamin A deficiency. ⬇️

scientific article

Expression profiles of tyrosine kinases in cultured follicular papilla cells versus dermal fibroblasts.

scientific article published in August 2004

Extracellular matrix changes in human corneas after radial keratotomy

scientific article published on 01 September 1998

Functional importance of an Sp1- and an NFkB-related nuclear protein in a keratinocyte-specific promoter of rabbit K3 keratin gene.

scientific article

Gene deletion in urothelium by specific expression of Cre recombinase

scientific article published on 19 April 2005

Generation of divergent uroplakin tetraspanins and their partners during vertebrate evolution: identification of novel uroplakins

scientific article (publication date: 23 January 2014)

Hair follicle stem cells.

scientific article

Hair follicle stem cells: present concepts.

scientific article published in May 1995

Human corneal basement membrane heterogeneity: topographical differences in the expression of type IV collagen and laminin isoforms

scientific article published on 01 April 1995

Human epithelial cells cultured from urine: growth properties and keratin staining

scientific article published on 01 October 1980

Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis

scientific article published on 25 January 2007

Identification of an 85-100 kDa glycoprotein as a cell surface marker for an advanced stage of urothelial differentiation: association with the inter-plaque ('hinge') area

scientific article published on 01 January 1992

Identification of mouse mammary epithelial cells by immunofluorescence with rabbit and guinea pig antikeratin antisera

scientific article

Immunofluorescent staining of keratin fibers in cultured cells ⬇️

scientific article published on July 1, 1978

Immunohistochemical study of nasopharyngeal carcinoma using monoclonal keratin antibodies

scientific article published in October 1984

Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies

scientific article

In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: relation to urinary tract infections

scientific article published on September 1996

Interaction between dermal papilla and bulge: the rhino mouse mutation as a model system

scientific article published on 01 December 1991

Interaction of filaggrin with keratin filaments during advanced stages of normal human epidermal differentiation and in ichthyosis vulgaris

scientific article published on 01 September 1991

Interaction of trichohyalin with intermediate filaments: three immunologically defined stages of trichohyalin maturation

scientific article published on 01 January 1992

Interpreting epithelial cancer biology in the context of stem cells: tumor properties and therapeutic implications.

scientific article

Intrinsic and extrinsic regulation of the differentiation of skin, corneal and esophageal epithelial cells

scientific article published on 01 November 1980

Intron evolution: testing hypotheses of intron evolution using the phylogenomics of tetraspanins

scientific article (publication date: 2009)

Involvement of follicular stem cells in forming not only the follicle but also the epidermis

scientific article published on 01 August 2000

Involvement of vps33a in the fusion of uroplakin-degrading multivesicular bodies with lysosomes

scientific article published on 26 May 2009

Irwin Freedberg: physician-scientist and mentor.

scientific article published in March 2006

Keratin classes: molecular markers for different types of epithelial differentiation.

scientific article

Keratin cytoskeletons in epithelial cells of internal organs ⬇️

scientific article published on June 1, 1979

Keratin expression during normal epidermal differentiation.

scientific article published on January 1983

Keratin filaments of corneal epithelial cells

scientific article published on 01 January 1981

Keratin filaments of cultured human epidermal cells. Formation of intermolecular disulfide bonds during terminal differentiation ⬇️

scientific article published on March 25, 1978

Label-retaining cells are preferentially located in fornical epithelium: implications on conjunctival epithelial homeostasis

scientific article published on 01 January 1995

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis

scientific article (publication date: 29 June 1990)

Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity

scientific article

Large scale purification and immunolocalization of bovine uroplakins I, II, and III. Molecular markers of urothelial differentiation

scientific article published on 01 November 1990

MAL facilitates the incorporation of exocytic uroplakin-delivering vesicles into the apical membrane of urothelial umbrella cells.

scientific article published on 9 February 2012

Message of nexin 1, a serine protease inhibitor, is accumulated in the follicular papilla during anagen of the hair cycle

scientific article published on 01 December 1995

Methyl 4-mercaptobutyrimidate as a cleavable crosslinking reagent and its application to the Escherichia coli 30S ribosome ⬇️

scientific article published on August 14, 1973

Microcirculation in chronic viral hepatitis: clinical observation and treatment with traditional Chinese medicine.

scientific article published in August 1986

Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes ⬇️

scientific article published on April 1, 1984

Monoclonal antibody studies of mammalian epithelial keratins: a review.

scientific article published on January 1985

Morphologic and clinical observations in human infection with Babesia microti

scientific article published on 01 August 1983

Mouse skin is particularly susceptible to tumor initiation during early anagen of the hair cycle: possible involvement of hair follicle stem cells.

scientific article published in October 1993

Organization of uroplakin subunits: transmembrane topology, pair formation and plaque composition

scientific article

Origin of the tetraspanin uroplakins and their co-evolution with associated proteins: implications for uroplakin structure and function.

scientific article

Osteopontin gene is expressed in the dermal papilla of pelage follicles in a hair-cycle-dependent manner

scientific article published on 01 December 2001

Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function.

scientific article

Overexpression of epidermal growth factor receptor in urothelium elicits urothelial hyperplasia and promotes bladder tumor growth.

scientific article

Patterns of keratin expression define distinct pathways of epithelial development and differentiation.

scientific article published on January 1987

Phorbol ester preferentially stimulates mouse fornical conjunctival and limbal epithelial cells to proliferate in vivo.

scientific article published on February 1998

Possible mechanisms for the loss of goblet cells in mucin-deficient disorders

scientific article published on 01 June 1984

Posterior polymorphous dystrophy of the cornea: cell culture studies

scientific article published on 01 November 1981

Primary uroepithelial cultures. A model system to analyze umbrella cell barrier function.

scientific article

Properties of an epithelial cell type in culture: the epidermal keratinocyte and its dependence on products of the fibroblast

scientific article published on 01 January 1977

Protein-protein proximity in the association of ribosomal subunits of Escherichia coli: crosslinking of 30 S protein S16 to 50 S proteins by glutaraldehyde or formaldehyde

scientific article published on 01 August 1974

Proteus mirabilis fimbriae- and urease-dependent clusters assemble in an extracellular niche to initiate bladder stone formation.

scientific article published on 4 April 2016

Rab27b association with melanosomes: dominant negative mutants disrupt melanosomal movement.

scientific article

Rabbit conjunctival and corneal epithelial cells belong to two separate lineages.

scientific article published on March 1996

Rapid communication: BamHI and TaqI restriction fragment length polymorphisms in the bovine Uroplakin IA gene

scientific article published on 01 July 1994

Rapid communication: PstI, HindIII, and TaqI restriction fragment length polymorphisms in the bovine Uroplakin IB gene

scientific article published on 01 July 1994

Rapid modulation of keratinocyte differentiation by the external environment.

scientific article published on April 1983

Regulation of K3 keratin gene transcription by Sp1 and AP-2 in differentiating rabbit corneal epithelial cells.

scientific article published on June 1997

Retinoid signaling in progenitors controls specification and regeneration of the urothelium

scientific article

Role of Ha-ras activation in superficial papillary pathway of urothelial tumor formation

scientific article published on 01 April 2001

Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases.

scientific article

SNX31: a novel sorting nexin associated with the uroplakin-degrading multivesicular bodies in terminally differentiated urothelial cells

scientific journal article

Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells

scientific article published on 23 March 2016

Serpins in the human hair follicle

scientific article published on 01 May 2000

Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends.

scientific article

Similarity in the size and number of ribosomal proteins from different prokaryotes.

scientific article published on August 1972

Simple epithelial nature of some simian virus-40-transformed human epidermal keratinocytes ⬇️

scientific article published on December 1, 1984

Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum

scientific article

Specific keratins as molecular markers for neoplasms with a stratified epithelial origin

scientific article published on 01 April 1984

Spiny keratoderma--a demonstration of hair keratin and hair type keratinization

scientific article published on 01 January 1999

Stem Cells of Pelage, Vibrissae, and Eyelash Follicles: The Hair Cycle and Tumor Formationa ⬇️

scientific article published on December 26, 1991

Strategies of epithelial repair: modulation of stem cell and transit amplifying cell proliferation

scientific article published on 01 October 1998

Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-A resolution.

scientific article

Structural basis of urothelial permeability barrier function as revealed by Cryo-EM studies of the 16 nm uroplakin particle.

scientific article published on October 2003

Suprabasal change and subsequent formation of disulfide-stabilized homo- and hetero-dimers of keratins during esophageal epithelial differentiation.

scientific article published on March 1993

Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling

scientific journal article

TaqI and BglII RFLPs for the bovine uroplakin III loci UPK3A and UPK3B

scientific article published on 01 February 1994

Temporally and spatially controllable gene expression and knockout in mouse urothelium.

scientific article

The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies.

scientific article

The Tetraspanin-Associated Uroplakins Family (UPK2/3) Is Evolutionarily Related to PTPRQ, a Phosphotyrosine Phosphatase Receptor

scientific article

The Use of Monoclonal Antibody to Keratin in Human Epidermal Disease: Alterations in Immunohistochemical Staining Pattern ⬇️

scientific article published on September 1, 1983

The bladder as a bioreactor: urothelium production and secretion of growth hormone into urine

scientific article published on 01 January 1998

The fibrillar substructure of keratin filaments unraveled.

scientific article

The functional and structural homology of ribosomal protein S7 of E. coli strains K and MRE600

scientific article published on 01 March 1973

The protein topography of the E. coli 30S ribosomal subunit: a preliminary model E. coli/30S subunit/ribosome/spatial arrangement of proteins

scientific article published on January 31, 1975

The use of aIF, AE1, and AE3 monoclonal antibodies for the identification and classification of mammalian epithelial keratins

scientific article published on 01 January 1984

The use of antikeratin antibodies for the identification of cultured epithelial cells

scientific article published on 01 January 1980

The use of antikeratin antiserum as a diagnostic tool: thymoma versus lymphoma

scientific article published on 01 November 1980

Three-dimensional analysis of the 16 nm urothelial plaque particle: luminal surface exposure, preferential head-to-head interaction, and hinge formation

scientific article published on 01 January 1999

Thrombin potentiates the mitogenic response of cultured fibroblasts to serum and other growth promoting agents

scientific article published on 01 August 1977

Topography of ribosomal proteins of the Escherichia coli 30S subunit as studied with the reversible cross-linking reagent methyl 4-mercaptobutyrimidate

scientific article published on 01 May 1974

Towards the molecular architecture of the asymmetric unit membrane of the mammalian urinary bladder epithelium: a closed "twisted ribbon" structure

scientific article published on 01 May 1995

Transient expression of mouse hair keratins in transfected HeLa cells: interactions between "hard" and "soft" keratins

scientific article published on 01 August 1991

Upper human hair follicle contains a subpopulation of keratinocytes with superior in vitro proliferative potential.

scientific article published on November 1993

Uroplakin I: a 27-kD protein associated with the asymmetric unit membrane of mammalian urothelium.

scientific article

Uroplakin II gene is expressed in transitional cell carcinoma but not in bilharzial bladder squamous cell carcinoma: alternative pathways of bladder epithelial differentiation and tumor formation

scientific article

Uroplakin as a marker for typing metastatic transitional cell carcinoma on fine-needle aspiration specimens

scientific article published on 01 June 2001

Uroplakins as markers of urothelial differentiation.

scientific article

Uroplakins do not restrict CO2 transport through urothelium

scientific article published on 7 February 2012

Urothelial function reconsidered: a new role in urinary protein secretion

scientific article published on 01 June 2001

Urothelial function reconsidered: a role in urinary protein secretion

scientific article published on January 2001

Urothelial hinge as a highly specialized membrane: detergent-insolubility, urohingin association, and in vitro formation

scientific article published on 01 July 1999

Urothelial umbrella cells of human ureter are heterogeneous with respect to their uroplakin composition: different degrees of urothelial maturity in ureter and bladder?

scientific article published on 01 March 2005

Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma

scientific article published on 01 July 1999

Use of nitrocellulose membranes for protein characterization by matrix-assisted laser desorption/ionization mass spectrometry.

scientific article published in July 2006

Voiding pattern analysis as a surrogate for cystometric evaluation in uroplakin II knockout mice.

scientific article published on 19 March 2008

Wnt signals are targets and mediators of Gli function.

scientific article published in May 2001

[Evidence that uroplakins exist in the intermediate cell of mouse bladder epithelium]

scientific article published on 01 March 1995

[Uroplakin III, a specific membrane protein of urothelial umbrella cells, as a histological markers for metastatic transitional cell carcinomas]

scientific article

p53 deficiency provokes urothelial proliferation and synergizes with activated Ha-ras in promoting urothelial tumorigenesis.

scientific article published on January 2004

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