Search filters

List of works by Takumi Misaka

A gustatory cyclic nucleotide-gated channels CNGgust, is expressed in the retina

scientific article published on 01 March 1999

A large increase of sour taste receptor cells in Skn-1-deficient mice does not alter the number of their sour taste signal-transmitting gustatory neurons.

scientific article published on 27 March 2017

A water channel closely related to rat brain aquaporin 4 is expressed in acid- and pepsinogen-secretory cells of human stomach.

scientific article published in March 1996

Accumulation of SNAP25 in mouse gustatory and somatosensory cortices in response to food and chemical stimulation.

scientific article published on 26 May 2012

Acid-induced sweetness of neoculin is ascribed to its pH-dependent agonistic-antagonistic interaction with human sweet taste receptor.

scientific article published on 8 February 2008

Activation of the Chemosensory Ion Channels TRPA1 and TRPV1 by Hydroalcohol Extract of Kalopanax pictus Leaves.

scientific article published on November 2012

Activation of the hTAS2R14 human bitter-taste receptor by (-)-epigallocatechin gallate and (-)-epicatechin gallate.

scientific article

Advanced method for high-throughput expression of mutated eukaryotic membrane proteins in Saccharomyces cerevisiae.

scientific article published on 12 May 2008

Amiloride reduces the sweet taste intensity by inhibiting the human sweet taste receptor.

scientific article

Analysis of aging-dependent changes in taste sensitivities of the senescence-accelerated mouse SAMP1

scientific article published on 20 September 2018

Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation.

scientific article published on 7 July 2008

Aquaporin-9 is expressed in a mucus-secreting goblet cell subset in the small intestine.

scientific article

Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells.

scientific article published on 21 July 2006

Artepillin C, a major ingredient of Brazilian propolis, induces a pungent taste by activating TRPA1 channels

scientific article

Biochemical and genomic analysis of neoculin compared to monocot mannose-binding lectins.

scientific article

Bulky high-mannose-type N-glycan blocks the taste-modifying activity of miraculin

scientific article published on 11 June 2010

Characterization of ligands for fish taste receptors.

scientific article published on May 2007

Characterization of the Human Bitter Taste Receptor Response to Sesquiterpene Lactones from Edible Asteraceae Species and Suppression of Bitterness through pH Control

scientific article published on 01 February 2021

Characterization of the modes of binding between human sweet taste receptor and low-molecular-weight sweet compounds

scientific article

Chimeric yeast G-protein α subunit harboring a 37-residue C-terminal gustducin-specific sequence is functional in Saccharomyces cerevisiae.

scientific article published in January 2012

Construction of a taste-blind medaka fish and quantitative assay of its preference-aversion behavior.

scientific article

Crystal structure of glucansucrase from the dental caries pathogen Streptococcus mutans

scientific article

Crystal structure of neoculin: insights into its sweetness and taste-modifying activity.

scientific article published on 29 March 2006

Crystallization and preliminary X-ray analysis of a glucansucrase from the dental caries pathogen Streptococcus mutans.

scientific article published on 28 August 2010

Cysteine-to-serine shuffling using a Saccharomyces cerevisiae expression system improves protein secretion: case of a nonglycosylated mutant of miraculin, a taste-modifying protein.

scientific article

Dietary flavonoids activate the constitutive androstane receptor (CAR).

scientific article

Dietary zinc status reversibly alters both the feeding behaviors of the rats and gene expression patterns in diencephalon.

scientific article

Differential expression analysis throughout the weaning period in the mouse cerebral cortex.

scientific article published on 16 January 2013

Differential expression of wheat aspartic proteinases, WAP1 and WAP2, in germinating and maturing seeds

scientific article

Establishment of a New Cell-Based Assay To Measure the Activity of Sweeteners in Fluorescent Food Extracts ⬇️

scientific article published on October 20, 2011

Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39 ⬇️

scientific article published on January 25, 2011

Expression of serotonin receptor genes in cranial ganglia

scientific article published on 05 February 2016

Expression of the synaptic exocytosis-regulating molecule complexin 2 in taste buds and its participation in peripheral taste transduction.

scientific article published on 23 March 2015

Extracellular production of neoculin, a sweet-tasting heterodimeric protein with taste-modifying activity, by Aspergillus oryzae.

scientific article published on May 2006

Fluorescence-based optimization of human bitter taste receptor expression in Saccharomyces cerevisiae

scientific article

Food functionality research as a new national project in special reference to improvement of cognitive and locomotive abilities

scientific article published on 10 January 2018

Functional diversity of bitter taste receptor TAS2R16 in primates

scientific article published on 7 March 2012

Gliadain, a gibberellin-inducible cysteine proteinase occurring in germinating seeds of wheat, Triticum aestivum L., specifically digests gliadin and is regulated by intrinsic cystatins.

scientific article published on 20 March 2007

Hepatic gene expression of the insulin signaling pathway is altered by administration of persimmon peel extract: a DNA microarray study using type 2 diabetic Goto-Kakizaki rats

scientific article published on 03 March 2011

Human bitter taste receptors hTAS2R8 and hTAS2R39 with differential functions to recognize bitter peptides

scientific article published on 13 June 2011

Human sweet taste receptor mediates acid-induced sweetness of miraculin ⬇️

scientific article published on September 26, 2011

Hypothalamic neuronal circuits regulating hunger-induced taste modification

scientific article published on 08 October 2019

Identification and modulation of the key amino acid residue responsible for the pH sensitivity of neoculin, a taste-modifying protein

scientific article

Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor

scientific article

L-Theanine elicits umami taste via the T1R1 + T1R3 umami taste receptor.

scientific article

Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter niemann-pick c1-like 1 in caco-2 cells and rats.

scientific article

Methyl syringate, a low-molecular-weight phenolic ester, as an activator of the chemosensory ion channel TRPA1.

scientific article published on 21 December 2012

Microbial production of sensory-active miraculin.

scientific article

Modulation of sweet taste by umami compounds via sweet taste receptor subunit hT1R2.

scientific article published on 8 April 2015

Modulatory Effect of Theaflavins on Apical Sodium-Dependent Bile Acid Transporter (ASBT) Activity

scientific article published in 2021

Molecular cloning and taste bud-specific expression of a novel cyclic nucleotide-gated channel.

scientific article

Neoculin, a taste-modifying sweet protein, accumulates in ripening fruits of cultivated Curculigo latifolia.

scientific article

Neuron differentiation-related genes are up-regulated in the hypothalamus of odorant-inhaling rats subjected to acute restraint stress.

scientific article published in July 2010

Non-acidic compounds induce the intense sweet taste of neoculin, a taste-modifying protein

scientific article published on 07 August 2011

Novel indole and benzothiophene ring derivatives showing differential modulatory activity against human epithelial sodium channel subunits, ENaC β and γ

article

Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages.

scientific article published on 03 February 2014

OPA1 expression in the normal rat retina and optic nerve

scientific article

Participation of the peripheral taste system in aging-dependent changes in taste sensitivity.

scientific article published on 4 July 2017

Photoactive ligands probing the sweet taste receptor. Design and synthesis of highly potent diazirinyl D-phenylalanine derivatives.

scientific article

Positive/Negative Allosteric Modulation Switching in an Umami Taste Receptor (T1R1/T1R3) by a Natural Flavor Compound, Methional

scientific article published in Scientific Reports

Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis

scientific article

Rapid Expansion of Phenylthiocarbamide Non-Tasters among Japanese Macaques.

scientific article published on 22 July 2015

SatB2-Expressing Neurons in the Parabrachial Nucleus Encode Sweet Taste

scientific article published on 01 May 2019

Sensory biology. Evolution of sweet taste perception in hummingbirds by transformation of the ancestral umami receptor.

scientific article

Signal peptide peptidase and its homologs in Arabidopsis thaliana--plant tissue-specific expression and distinct subcellular localization

scientific article

Soy peptides enhance heterologous membrane protein productivity during the exponential growth phase of Saccharomyces cerevisiae

scientific article published on 01 January 2012

Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor

scientific article published on 18 March 2019

Surface plasmon resonance analysis on interactions of food components with a taste epithelial cell model.

scientific article published on November 2010

Tas2r125 functions as the main receptor for detecting bitterness of tea catechins in the oral cavity of mice

scientific article published on 02 July 2018

Taste buds have a cyclic nucleotide-activated channel, CNGgust

scientific journal article

Taste receptor cells express voltage-dependent potassium channels in a cell age-specific manner

scientific article published on 27 July 2006

The dynamin-related mouse mitochondrial GTPase OPA1 alters the structure of the mitochondrial inner membrane when exogenously introduced into COS-7 cells

scientific article published on 05 April 2006

The hepatic genes for immunoproteasome are upregulated by refeeding after fasting in the rat.

scientific article published on 7 June 2010

The human bitter taste receptor, hTAS2R16, discriminates slight differences in the configuration of disaccharides.

scientific article

The response of PKD1L3/PKD2L1 to acid stimuli is inhibited by capsaicin and its pungent analogs.

scientific article published on 16 April 2012

The single pore residue Asp523 in PKD2L1 determines Ca2+ permeation of the PKD1L3/PKD2L1 complex.

scientific article published on 23 December 2010

The use of mammalian cultured cells loaded with a fluorescent dye shows specific membrane penetration of undissociated acetic acid

scientific article published on 01 January 2012

Transgenic labeling of higher order neuronal circuits linked to phospholipase C‐β2–expressing taste bud cells in medaka fish ⬇️

scientific article published on June 1, 2013

Transient receptor potential channel M5 and phospholipaseC-beta2 colocalizing in zebrafish taste receptor cells.

scientific article published in October 2007

Two distinct determinants of ligand specificity in T1R1/T1R3 (the umami taste receptor).

scientific article published on 8 November 2013

Ulex Europaeus Agglutinin-1 Is a Reliable Taste Bud Marker for In Situ Hybridization Analyses.

scientific article published on 30 December 2015

Umami taste dysfunction in patients receiving radiotherapy for head and neck cancer

scientific article published on 11 July 2008

Umami-bitter interactions: the suppression of bitterness by umami peptides via human bitter taste receptor

scientific article

Unilateral nasal obstruction alters sweet taste preference and sweet taste receptors in rat circumvallate papillae

scientific article published on 23 November 2018

Utilization of Oryzacystatin for Regulating the Ripening of Squid Shiokara, a Traditional Japanese Salted and Fermented Seafood ⬇️

scientific article published on October 15, 2010

Variation in ligand responses of the bitter taste receptors TAS2R1 and TAS2R4 among New World monkeys.

scientific article

Wheat cysteine proteases triticain alpha, beta and gamma exhibit mutually distinct responses to gibberellin in germinating seeds

scientific article published on 29 April 2008

pH-Dependent inhibition of the human bitter taste receptor hTAS2R16 by a variety of acidic substances.

scientific article

pH-Dependent structural change in neoculin with special reference to its taste-modifying activity.

scientific article published on 7 November 2009

Paulina is supported by:

About Paulina

Help