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List of works by Manuel Portolés

20 years of leptin: Role of leptin in cardiomyocyte physiology and physiopathology

scientific article

24 h nesfatin-1 treatment promotes apoptosis in cardiomyocytes.

scientific article

A new case of arginase deficiency in a Spanish male

article

ATP synthase subunit alpha and LV mass in ischaemic human hearts

scientific article published on 9 November 2014

Cardiac protein changes in ischaemic and dilated cardiomyopathy: a proteomic study of human left ventricular tissue

scientific article published on October 2012

Circulating Sphingosine-1-Phosphate as A Non-Invasive Biomarker of Heart Transplant Rejection

scientific article published on 25 September 2019

Circulating biomarkers of collagen metabolism in arterial hypertension: relevance of target organ damage.

scientific article

Differences in MEF2 and NFAT transcriptional pathways according to human heart failure aetiology

scientific article

Differential gene expression of C-type natriuretic peptide and its related molecules in dilated and ischemic cardiomyopathy. A new option for the management of heart failure

scientific article published on 15 April 2014

Differential gene expression of cardiac ion channels in human dilated cardiomyopathy

scientific article

Does the calcineurin inhibitor have influence on cytomegalovirus infection in heart transplantation?

scientific article published on 11 December 2013

Effect of L-carnitine on ketone bodies, redox state and free amino acids in the liver of hyperammonemic mice

scientific article published on 01 October 1987

Effect of caffeine on urea biosynthesis and some related processes, ketone bodies, ATP and liver amino acids.

scientific article published in August 1989

Effect of hyperammonemia on brain amino acids in young and adult ferrets.

scientific article published in June 1993

Effects of inhibition of ornithine aminotransferase or of general aminotransferases on urea and citrulline synthesis and on the levels of acetylglutamate in isolated rat hepatocytes

scientific article published on 01 February 1988

Electron Microscopy Reveals Evidence of Perinuclear Clustering of Mitochondria in Cardiac Biopsy-Proven Allograft Rejection

scientific article published in 2022

Endolysosomal two-pore channels regulate autophagy in cardiomyocytes.

scientific article published on 12 January 2016

Endoplasmic reticulum stress induces different molecular structural alterations in human dilated and ischemic cardiomyopathy

scientific article

Ethanol affects calmodulin and the calmodulin-binding proteins neuronal nitric oxide synthase and alphaII-spectrin (alpha-fodrin) in the nucleus of growing and differentiated rat astrocytes in primary culture.

scientific article published on 27 March 2007

Functional networks of nucleocytoplasmic transport-related genes differentiate ischemic and dilated cardiomyopathies. A new therapeutic opportunity

scientific article

Gene expression network analysis reveals new transcriptional regulators as novel factors in human ischemic cardiomyopathy

scientific article

Heart failure entails significant changes in human nucleocytoplasmic transport gene expression

scientific article published on 04 May 2013

Heart failure induces significant changes in nuclear pore complex of human cardiomyocytes.

scientific article

Heart mitochondrial proteome study elucidates changes in cardiac energy metabolism and antioxidant PRDX3 in human dilated cardiomyopathy

scientific article

High-performance liquid chromatographic assay of argininosuccinate: its application in argininosuccinic aciduria and in normal man

scientific article published on 01 January 1986

Human Ischemic Cardiomyopathy Shows Cardiac Nos1 Translocation and its Increased Levels are Related to Left Ventricular Performance

scientific article published on 4 April 2016

Impact of basal heart rate on long-term prognosis of heart transplant patients.

scientific article

Impact of cardiovascular risk factors and inflammatory status on urinary 8-OHdG in essential hypertension

scientific article published on 03 November 2011

Impact of glomerular filtration rate on urinary BNP and NT-proBNP levels in heart failure.

scientific article published on 20 January 2012

In vitro effect of caffeine on some aspects of nitrogen metabolism in isolated rat hepatocytes

scientific article published on 01 October 1988

Incidence of development of obesity after heart transplantation according to the calcineurin inhibitor.

scientific article published in January 2015

Inflammation and apoptosis in hypertension. Relevance of the extent of target organ damage

scientific article published on 07 July 2012

Influence of heart failure on nucleocytoplasmic transport in human cardiomyocytes

scientific article

Influence of heart failure on nucleolar organization and protein expression in human hearts

scientific article published on 08 January 2012

Influence of metabolic syndrome on development of cardiac allograft vasculopathy in the transplanted heart

scientific article published on 01 January 2012

Left ventricular cavity area reflects N-terminal pro-brain natriuretic peptide plasma levels in heart failure.

scientific article

Lesch-Nyhan Syndrome, Caffeine Model: Increase of Purine and Pyrimidine Enzymes in Rat Brain ⬇️

scientific article published on December 1, 1984

Long-term high-protein diet induces biochemical and ultrastructural changes in rat liver mitochondria

scientific article published on 01 September 1988

Long-term prognostic implications of metabolic syndrome in heart transplant recipients.

scientific article published in July 2011

Low density lipoprotein receptor-related protein 1 expression correlates with cholesteryl ester accumulation in the myocardium of ischemic cardiomyopathy patients.

scientific article

Metabolic syndrome in heart transplantation: impact on survival and renal function.

scientific article

Mycophenolate acid vs mycophenolate mofetil therapy.

scientific article published on October 2010

Nesfatin-1 in human and murine cardiomyocytes: synthesis, secretion, and mobilization of GLUT-4

scientific article published on 24 September 2013

New Cell Adhesion Molecules in Human Ischemic Cardiomyopathy. PCDHGA3 Implications in Decreased Stroke Volume and Ventricular Dysfunction

scientific article

Non-ketotic hyperglycinaemia: prenatal diagnosis and detection of heterozygotes with glycine/serine ratios.

scientific article published in January 1987

Obese and nonobese patients with essential hypertension show similar N-terminal proBNP plasma levels

scientific article published on 24 April 2008

Obese subjects with heart failure have lower N-terminal pro-brain natriuretic peptide plasma levels irrespective of aetiology

scientific article published on 05 August 2005

Patients with Dilated Cardiomyopathy and Sustained Monomorphic Ventricular Tachycardia Show Up-Regulation of KCNN3 and KCNJ2 Genes and CACNG8-Linked Left Ventricular Dysfunction

scientific article published on 28 December 2015

Plasma concentration of big endothelin-1 and its relation with plasma NT-proBNP and ventricular function in heart failure patients

scientific article

Prenatal ethanol exposure alters the cytoskeleton and induces glycoprotein microheterogeneity in rat newborn hepatocytes.

scientific article published in May 2004

Protein Inhibitor of NOS1 Plays a Central Role in the Regulation of NOS1 Activity in Human Dilated Hearts.

scientific article published on 02 August 2016

RNA sequencing analysis and atrial natriuretic peptide production in patients with dilated and ischemic cardiomyopathy

scientific article

RNA sequencing analysis identifies new human collagen genes involved in cardiac remodeling.

scientific article published in March 2015

RNA-sequencing analysis reveals new alterations in cardiomyocyte cytoskeletal genes in patients with heart failure

scientific article published on 07 April 2014

Rats fed prolonged high protein diets show an increase in nitrogen metabolism and liver megamitochondria

scientific article published on 01 November 1987

Rats that consume caffeine show decreased brain protein synthesis.

scientific article published in January 1986

Serum markers of apoptosis in the early period of heart transplantation

scientific article published on 22 March 2012

Subjective symptoms related to GSM radiation from mobile phone base stations: a cross-sectional study.

scientific article

Sum of effects of myocardial ischemia followed by electrically induced tachycardia on myocardial function

scientific article published on 31 May 2013

TRPM7 is down-regulated in both left atria and left ventricle of ischaemic cardiomyopathy patients and highly related to changes in ventricular function.

scientific article published on 23 March 2016

The Adipokine Chemerin Induces Apoptosis in Cardiomyocytes.

scientific article published on 20 August 2015

The altered expression of autophagy-related genes participates in heart failure: NRBP2 and CALCOCO2 are associated with left ventricular dysfunction parameters in human dilated cardiomyopathy

article

The role of the nuclear lamins in the pathogenesis of heart failure in patients undergoing cardiac transplantation

scientific article published on 01 July 2009

Thyroid Hormone Levels in Rats Exposed to Alcohol during Development ⬇️

scientific article published on 01 May 1988

Timing, etiology, and location of first infection in first year after heart transplantation

scientific article published on 01 October 2010

Urinary B-type natriuretic peptide levels in the diagnosis and prognosis of heart failure

scientific article published on 01 September 2007

Variability of NT-proBNP and its relationship with inflammatory status in patients with stable essential hypertension: a 2-year follow-up study.

scientific article

XPO1 Gene Therapy Attenuates Cardiac Dysfunction in Rats with Chronic Induced Myocardial Infarction

scientific article published on 25 November 2019

[8-hydroxy-2'-deoxyguanosine and lipid peroxidation in patients with heart failure]

scientific article published on 01 November 2006

[Immunological alterations and selectin values in hypertensive patients treated according to current criteria]

scientific article published on 08 December 2010

[Ischemic preconditioning. Is it always a beneficial phenomenon?]

scientific article published on 01 June 1999

[Long-term prognosis of serum and urine n-terminal proBNP levels and glomerular filtration rate in heart failure patients]

scientific article published on 29 December 2009

[Nuclear changes and p62 expression in ischemic and dilated cardiomyopathy]

scientific article published on 01 December 2007

[Prognostic value of big endothelin-1 prognostic value in patients with heart failure and moderately symptomatic functional class]

scientific article published on 18 April 2009

[Relationship between myocardial modelling and diastolic function in patients with essential hypertension]

scientific article published on 28 October 2011

[Urinary NT-proBNP level: relationship with ventricular function parameters in heart failure]

scientific article published on 01 May 2007

[Urinary levels of B-type natriuretic peptide (BNP) and ventricular systolic dysfunction in heart failure patients]

scientific article published on 01 April 2009

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