List of works by David C. Smith

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors

scientific article published on 27 September 2017

A phase 2 trial of salvage radiation and concurrent weekly docetaxel after a rising prostate-specific antigen level after radical prostatectomy

scientific article published on 9 December 2015

A phase I dose escalation and expansion study of the anticancer stem cell agent demcizumab (anti-DLL4) in patients with previously treated solid tumors.

scientific article

A phase I open-label trial evaluating the cardiovascular safety of regorafenib in patients with advanced cancer.

scientific article published on 18 August 2015

A phase I trial of high-dose continuous-infusion hydroxyurea.

scientific article

A phase I trial of high-dose oral tamoxifen and CHOPE

scientific article published on 01 January 1995

A phase II trial of CI-958 in patients with hormone-refractory prostate cancer.

scientific article

A phase II trial of all-trans-retinoic acid in hormone-refractory prostate cancer: a clinical trial with detailed pharmacokinetic analysis

scientific article published on 01 January 1997

A phase II trial of neoadjuvant nab-paclitaxel, carboplatin, and gemcitabine (ACaG) in patients with locally advanced carcinoma of the bladder

scientific article

A phase II trial of oral diethylstilbesterol as a second-line hormonal agent in advanced prostate cancer.

scientific article published in August 1998

A phase ii trial of oral estramustine and oral etoposide in hormone refractory prostate cancer

scientific article published on 01 September 1997

A randomized phase 2 trial of gemcitabine/cisplatin with or without cetuximab in patients with advanced urothelial carcinoma.

scientific article

A randomized phase II study of cediranib alone versus cediranib in combination with dasatinib in docetaxel resistant, castration resistant prostate cancer patients

scientific article

A sequential treatment approach to myoinvasive urothelial cancer: a phase II Southwest Oncology Group trial (S0219).

scientific article published on 16 April 2009

Academic Cancer Center Phase I Program Development

scientific article

Adjuvant and neoadjuvant therapy in prostate cancer.

scientific article

Advances in prostate cancer chemotherapy: a new era begins.

scientific article

All-trans-retinoic acid modulation of drug-metabolizing enzyme activities: investigation with selective metabolic drug probes

scientific article published on 01 January 1998

American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors.

scientific article published on 7 June 2010

Association between Agent Orange and prostate cancer: a pilot case-control study

scientific article published in April 2004

Change in serum prostate-specific antigen as a marker of response to cytotoxic therapy for hormone-refractory prostate cancer

scientific article published on 01 May 1998

Characterization of bone metastases from rapid autopsies of prostate cancer patients

scientific article published on 9 May 2011

Chemotherapy for hormone refractory prostate cancer.

scientific article

Chemotherapy for localized, high-risk prostate cancer

scientific article published on April 1, 2003

Cilengitide (EMD 121974, NSC 707544) in asymptomatic metastatic castration resistant prostate cancer patients: a randomized phase II trial by the prostate cancer clinical trials consortium

scientific article published on 25 March 2010

Combined-modality therapy with gemcitabine and radiation therapy as a bladder preservation strategy: long-term results of a phase I trial

scientific article published on 30 October 2008

Combined-modality therapy with gemcitabine and radiotherapy as a bladder preservation strategy: results of a phase I trial

scientific article

Course of distress and quality of life in testicular cancer patients before, during, and after chemotherapy: results of a pilot study

scientific article published in December 2003

Development of 2 Bromodomain and Extraterminal Inhibitors With Distinct Pharmacokinetic and Pharmacodynamic Profiles for the Treatment of Advanced Malignancies

scientific article published on 16 September 2019

Dose escalation of oral vinorelbine in combination with estramustine in hormone-refractory adenocarcinoma of the prostate

scientific article published on 01 June 2006

Double-blind, randomized, phase 2 trial of maintenance sunitinib versus placebo after response to chemotherapy in patients with advanced urothelial carcinoma

scientific article

Efficient delivery of radical cystectomy after neoadjuvant chemotherapy for muscle-invasive bladder cancer: a multidisciplinary approach

scientific article published on 19 May 2011

Electrocardiographic Characterization of Ramucirumab on the Corrected QT Interval in a Phase II Study of Patients With Advanced Solid Tumors

scientific article published on 16 March 2016

Enhancement of 1,25-dihydroxyvitamin D3-mediated antitumor activity with dexamethasone

scientific article published on 01 January 1998

Evaluation of the effect of necitumumab on the corrected QT interval in patients with advanced solid tumors.

scientific article published on 16 June 2016

First-in-human multicenter phase I study of BMS-936561 (MDX-1203), an antibody-drug conjugate targeting CD70.

scientific article

High-dose oral tamoxifen, a potential multidrug-resistance-reversal agent: phase I trial in combination with vinblastine

scientific article published on December 2, 1992

Hypercalcemia and neuroendocrine carcinoma of the prostate: a report of three cases and a review of the literature ⬇️

scientific article published on March 1, 1992

Integrative Clinical Genomics of Advanced Prostate Cancer.

scientific article

Integrative clinical genomics of advanced prostate cancer

scientific article

Ixabepilone, mitoxantrone, and prednisone for metastatic castration-resistant prostate cancer after docetaxel-based therapy: a phase 2 study of the Department Of Defense Prostate Cancer Clinical Trials Consortium

scientific article published on 29 December 2010

Lack of pharmacokinetic drug-drug interaction between ramucirumab and paclitaxel in a phase II study of patients with advanced malignant solid tumors.

scientific article published on 05 July 2016

Living with prostate cancer: patients' and spouses' psychosocial status and quality of life

scientific article published on 16 July 2007

Mechanistic Support for Combined MET and AR Blockade in Castration-Resistant Prostate Cancer.

scientific article published on January 2016

Megestrol acetate in the treatment of hormone refractory prostate cancer

scientific article published on 01 June 1997

Melanoma and immunotherapy bridge 2015 : Naples, Italy. 1-5 December 2015

scientific article

Multi-institutional randomized phase II trial of the epothilone B analog ixabepilone (BMS-247550) with or without estramustine phosphate in patients with progressive castrate metastatic prostate cancer.

scientific article published in March 2005

Multigene profiling of CTCs in mCRPC identifies a clinically relevant prognostic signature

scientific article published on 16 February 2018

Neoadjuvant docetaxel and estramustine chemotherapy in high-risk/locally advanced prostate cancer.

scientific article published in April 2003

ORAL CHEMOTHERAPY FOR HORMONE REFRACTORY PROSTATE CANCER

scientific article published on 01 May 1999

Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer

scientific article

Personalized oncology through integrative high-throughput sequencing: a pilot study

scientific article

Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies

scientific article

Phase I study of ixabepilone, mitoxantrone, and prednisone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel-based therapy: a study of the department of defense prostate cancer clinical trials consort

scientific article

Phase I study of vorinostat (suberoylanilide hydroxamic acid, NSC 701852) in combination with docetaxel in patients with advanced and relapsed solid malignancies.

scientific article published on 5 August 2010

Phase I trial of radiation dose escalation with concurrent weekly full-dose gemcitabine in patients with advanced pancreatic cancer.

scientific article published in November 2001

Phase I, Dose-Escalation, Two-Part Trial of the PARP Inhibitor Talazoparib in Patients with Advanced Germline BRCA1/2 Mutations and Selected Sporadic Cancers

scientific article

Phase II Evaluation of Oral Estramustine, Oral Etoposide, and Intravenous Paclitaxel in Patients with Hormone-Sensitive Prostate Adenocarcinoma

scientific article published on 01 June 2007

Phase II Evaluations of Cilengitide in Asymptomatic Patients with Androgen-Independent Prostate Cancer: Scientific Rationale and Study Design

article

Phase II evaluation of early oral estramustine, oral etoposide, and intravenous paclitaxel combined with hormonal therapy in patients with high-risk metastatic prostate adenocarcinoma: Southwest Oncology Group S0032

scientific article

Phase II randomised discontinuation trial of cabozantinib in patients with advanced solid tumours

scientific article published on 20 October 2017

Phase II study of cilengitide (EMD 121974, NSC 707544) in patients with non-metastatic castration resistant prostate cancer, NCI-6735. A study by the DOD/PCF prostate cancer clinical trials consortium

scientific article

Phase II study of first-line sagopilone plus prednisone in patients with castration-resistant prostate cancer: a phase II study of the Department of Defense Prostate Cancer Clinical Trials Consortium

scientific article

Phase II study of oral bis (aceto) ammine dichloro (cyclohexamine) platinum (IV) (JM-216, BMS-182751) given daily x 5 in hormone refractory prostate cancer (HRPC).

scientific article

Phase II trial and pharmacokinetic assessment of intravenous melphalan in patients with advanced prostate cancer

scientific article published on 01 January 1993

Phase II trial of combination nab-paclitaxel, carboplatin and gemcitabine in first line therapy of advanced urothelial carcinoma

scientific article

Phase II trial of copper depletion with tetrathiomolybdate as an antiangiogenesis strategy in patients with hormone-refractory prostate cancer.

scientific article

Phase II trial of oral 1,25-dihydroxyvitamin D (calcitriol) in hormone refractory prostate cancer

scientific article published on 01 September 1995

Phase II trial of oral cyclophosphamide, prednisone, and diethylstilbestrol for androgen-independent prostate carcinoma

scientific article published in October 2003

Phase II trial of oral uracil/tegafur plus leucovorin in patients with hormone-refractory prostate carcinoma

scientific article published in April 2006

Phase II trial of paclitaxel, carboplatin and gemcitabine in patients with locally advanced carcinoma of the bladder.

scientific article published on 18 October 2008

Phase II trial of paclitaxel, estramustine, etoposide, and carboplatin in the treatment of patients with hormone-refractory prostate carcinoma

scientific article

Phase II trial of suramin in patients with metastatic renal cell carcinoma

scientific article published on 01 January 1999

Population pharmacokinetics of hydroxyurea in cancer patients

scientific article published on 01 January 1995

Prospective quality-of-life assessment in patients receiving concurrent gemcitabine and radiotherapy as a bladder preservation strategy

scientific article

Quantitative analysis of ammonia on the breath of patients in end-stage renal failure

scientific article published on 01 July 1997

Randomized clinical trial of a family intervention for prostate cancer patients and their spouses

scientific article published in December 2007

Randomized, double-blind, placebo-controlled phase II trial of maintenance sunitinib versus placebo after chemotherapy for patients with advanced urothelial carcinoma: scientific rationale and study design

scientific article

Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy.

scientific article

Recombinant vaccinia-PSA (PROSTVAC) can induce a prostate-specific immune response in androgen-modulated human prostate cancer

scientific article published on 01 February 1999

Repurposing itraconazole as a treatment for advanced prostate cancer: a noncomparative randomized phase II trial in men with metastatic castration-resistant prostate cancer.

scientific article

Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: results of a first-in-man study.

scientific article

Small-molecule SMAC mimetics as new cancer therapeutics

scientific article

Survival, Durable Response, and Long-Term Safety in Patients With Previously Treated Advanced Renal Cell Carcinoma Receiving Nivolumab

scientific article published on 30 March 2015

THE USE OF PROSTATE-SPECIFIC ANTIGEN AS A SURROGATE END POINT IN THE TREATMENT OF PATIENTS WITH HORMONE REFRACTORY PROSTATE CANCER

scientific article published on 01 May 1997

The use of preferences to measure the benefit of adjuvant radiation therapy for stage I seminoma

scientific article published on 01 July 2002

Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: results of a multicenter phase II National Cancer Institute trial

scientific article published on 01 June 2007

Treatment of biochemical recurrence of prostate cancer with granulocyte-macrophage colony-stimulating factor secreting, allogeneic, cellular immunotherapy

scientific article published on 17 September 2008

Vorinostat in advanced prostate cancer patients progressing on prior chemotherapy (National Cancer Institute Trial 6862): trial results and interleukin-6 analysis: a study by the Department of Defense Prostate Cancer Clinical Trial Consortium [...]

scientific article

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