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List of works by Greg N. Brooke

Advances in genetics: widening our understanding of prostate cancer

scientific article

Allosteric conversation in the androgen receptor ligand-binding domain surfaces.

scientific article

Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells.

scientific article

Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells.

scientific article published on 7 November 2013

Circulating nucleic acids as biomarkers of prostate cancer.

scientific article published on December 2013

Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase.

scientific article published in January 2002

Engineered repressors are potent inhibitors of androgen receptor activity.

scientific article published on February 2014

FUS/TLS is a novel mediator of androgen-dependent cell-cycle progression and prostate cancer growth.

scientific article published on 17 December 2010

Gliotoxin is a dual inhibitor of farnesyltransferase and geranylgeranyltransferase I with antitumor activity against breast cancer in vivo.

scientific article published on January 2004

MSC.sTRAIL Has Better Efficacy than MSC.FL-TRAIL and in Combination with AKTi Blocks Pro-Metastatic Cytokine Production in Prostate Cancer Cells

scientific article published on 21 April 2019

Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression.

scientific article published on 26 November 2007

Mechanisms of androgen receptor repression in prostate cancer

scientific article published on 01 December 2006

Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer

scientific article published on 22 August 2014

Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I.

scientific article published in November 2003

Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens ⬇️

scientific article published on December 19, 2011

Revising the role of the androgen receptor in breast cancer.

scientific article

Role of the HSP90-Associated Cochaperone p23 in Enhancing Activity of the Androgen Receptor and Significance for Prostate Cancer ⬇️

scientific article published on August 16, 2012

The co-chaperone p23 promotes prostate cancer motility and metastasis

scientific article published on 6 September 2014

The role of androgen receptor mutations in prostate cancer progression.

scientific article published on March 2009

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