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List of works by John G Lock

A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime.

scientific article

A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo

scholarly article

Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions.

scientific article published on 9 April 2018

An analysis toolbox to explore mesenchymal migration heterogeneity reveals adaptive switching between distinct modes

scientific article

Cell-matrix adhesion complexes: master control machinery of cell migration.

scientific article published on 06 October 2007

Chemical biology approaches targeting the actin cytoskeleton through phenotypic screening

scientific article published on 19 March 2019

Clathrin-containing adhesion complexes

scientific article published on 17 June 2019

Disentangling Membrane Dynamics and Cell Migration; Differential Influences of F-actin and Cell-Matrix Adhesions

scientific article (publication date: 2015)

Domains of the TGN: coats, tethers and G proteins.

scientific article published on May 2004

E-cadherin transport from the trans-Golgi network in tubulovesicular carriers is selectively regulated by golgin-97

scientific article

GAIP participates in budding of membrane carriers at the trans-Golgi network

scientific article published on 01 March 2003

High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained

scientific article published on 09 October 2019

Integrin-mediated cell attachment induces a PAK4-dependent feedback loop regulating cell adhesion through modified integrin alpha v beta 5 clustering and turnover.

scientific article

KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration

scientific article published on 26 July 2018

Kindlin-2 is expressed in malignant mesothelioma and is required for tumor cell adhesion and migration.

scientific article

Mapping Phenotypic Plasticity upon the Cancer Cell State Landscape Using Manifold Learning

scientific article published in 2022

Non-monotonic cellular responses to heterogeneity in talin protein expression-level.

scientific article published on 22 May 2015

Plasticity in the macromolecular-scale causal networks of cell migration

scientific article (publication date: 2014)

PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation.

scientific article published in October 2010

Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin

scientific article

Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis

Single fluorescent protein-based Ca2+ sensors with increased dynamic range.

scientific article

TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis.

scientific article

Technical advance: live-imaging analysis of human dendritic cell migrating behavior under the influence of immune-stimulating reagents in an organotypic model of lung

scientific article

The GRIP domain is a specific targeting sequence for a population of trans-Golgi network derived tubulo-vesicular carriers.

scientific article published in May 2001

Using Systems Microscopy to Understand the Emergence of Cell Migration from Cell Organization.

scientific article published in January 2018