List of works - Hugo M. Santos

A comparison of depletion versus equalization for reducing high-abundance proteins in human serum

scientific article

A comprehensive factorial design study of variables affecting protein extraction from formalin-fixed kidney tissue samples.

scientific article published on 5 November 2013

A cost-effective method to get insight into the peritoneal dialysate effluent proteome

scientific article published on 20 May 2016

A journey through PROTEOSONICS.

scientific article published on 03 January 2014

A mesofluidic platform integrating on-chip probe ultrasonication for multiple sample pretreatment involving denaturation, reduction, and digestion in protein identification assays by mass spectrometry

scientific article published on 20 January 2014

A methodological approach based on gold-nanoparticles followed by matrix assisted laser desorption ionization time of flight mass spectrometry for the analysis of urine profiling of knee osteoarthritis

scientific article published on 29 June 2015

A new tripodal poly-imine indole-containing ligand: Synthesis, complexation, spectroscopic and theoretical studies

A novel (18)O inverse labeling-based workflow for accurate bottom-up mass spectrometry quantification of proteins separated by gel electrophoresis

scientific article

Absolute quantitative proteomics using the total protein approach to identify novel clinical immunohistochemical markers in renal neoplasms

scientific article published on 06 September 2021

Addendum

scientific article published on 01 August 2015

An assessment of the indirect high intensity ultrasonic assisted cleavage of complex proteomes with immobilized trypsin.

scientific article published on 22 December 2012

An assessment of the ultrasonic probe‐based enhancement of protein cleavage with immobilized trypsin ⬇️

scientific article published on September 7, 2011

An overview on sensing materials depending on the electromagnetic spectra region applied

Analytical Proteomics: An emerging field?

Analytical proteomics. Foreword.

scientific article

Binding of vanadium to human serum transferrin - voltammetric and spectrometric studies

scientific article published on 26 December 2017

Bioinspired Functionalized Nanoparticles as Tools for Detection, Quantification and Targeting of Biomolecules

Can sample treatments based on advanced oxidation processes assisted by high-intensity focused ultrasound be used for toxic arsenic determination in human urine by flow-injection hydride-generation atomic absorption spectrometry?

scientific article

Classifying patients in peritoneal dialysis by mass spectrometry-based profiling

scientific article

Combined proteomic and metallomic analyses in Scrobicularia plana clams to assess environmental pollution of estuarine ecosystems.

scientific article published on 2 September 2016

Complete proteome of a quinolone-resistant Salmonella Typhimurium phage type DT104B clinical strain

scientific article

Could transformation mechanisms of acetylase-harboring pMdT1 plasmid be evaluated through proteomic tools in Escherichia coli?

scientific article

Decision peptide-driven: a free software tool for accurate protein quantification using gel electrophoresis and matrix assisted laser desorption ionization time of flight mass spectrometry.

scientific article

Designing Eu-β-diketonate complexes as a support of ionic liquid crystals (ILCs) with additional luminescent properties

Development of a Robust Ultrasonic-Based Sample Treatment To Unravel the Proteome of OCT-Embedded Solid Tumor Biopsies

scientific article published on 19 June 2019

Development of a fast and efficient ultrasonic-based strategy for DNA fragmentation

article

Direct matrix assisted laser desorption ionization mass spectrometry-based analysis of wine as a powerful tool for classification purposes

scientific article

Dithiothreitol-based protein equalization technology to unravel biomarkers for bladder cancer

scientific article published on 6 December 2017

Editorial: Rational Design of Multi-Functional Nanomaterials

scientific article published on 24 May 2019

Effect of vancomycin on the proteome of the multiresistant Enterococcus faecium SU18 strain

scientific article published on 28 October 2014

Evaluation of the binding of four anti-tumor Casiopeínas® to human serum albumin

scientific article published on 29 July 2017

Exploiting anionic and cationic interactions with a new emissive imine-based β-naphthol molecular probe

Fast human serum profiling through chemical depletion coupled to gold-nanoparticle-assisted protein separation

scientific article

Foreword for special issue splicing 2016.

scientific article

Foreword ultrasonics 2016 special issue

scientific article published on 28 October 2017

From colorimetric chemosensors to metal nanoparticles using two new tyrosine Schiff-base ligands for Cu2+ detection

From visible to far-red excitable chromophores derivatives of vitamin B6. Evaluation as pH-responsive probes and solvatochromic study

Front Cover: Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual‐Color Flag (ChemistryOpen 1/2018).

scientific article published on 2 November 2017

Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual-Color Flag

scientific article published on 15 November 2017

Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual-Color Flag.

scientific article published on 7 November 2017

Improving sample treatment for in-solution protein identification by peptide mass fingerprint using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

scientific article

Interaction of [VIV O(acac)2 ] with Human Serum Transferrin and Albumin

scientific article

Label-free protein quantification after ultrafast digestion of complex proteomes using ultrasonic energy and immobilized-trypsin magnetic nanoparticles

scientific article published on 23 December 2018

Latest developments in sample treatment for 18O-isotopic labeling for proteomics mass spectrometry-based approaches: a critical review.

scientific article published on 04 May 2009

Light and colour as analytical detection tools: a journey into the periodic table using polyamines to bio-inspired systems as chemosensors

scientific article published on 14 June 2010

Mass Spectrometry-based Proteomics: What is it expecting ahead?

scientific article published on 01 August 2016

Mass-Up: an all-in-one open software application for MALDI-TOF mass spectrometry knowledge discovery.

scientific article

Metallothionein responses in the Asiatic clam (Corbicula fluminea) after exposure to trivalent arsenic

article

Modulating the protein content of complex proteomes using acetonitrile.

scientific article published on 31 January 2018

Multiomics Assessment of Gene Expression in a Clinical Strain of CTX-M-15-Producing ST131 Escherichia coli

article

New chemosensors based on thiomacrocycle-containing coumarin-343 fluoroionophor: X-ray structures and previous results on the effect of cation binding on the photophysical properties

New emissive dopamine derivatives as fluorescent chemosensors for metal ions: A CHEF effect for Al(III) interaction

scholarly article by Elisabete Oliveira et al published February 2012 in Inorganica Chimica Acta

Novel nanocomposites based on a strawberry-like gold- coated magnetite (Fe@Au) for protein separation in multiple myeloma serum samples

Novel versatile imine—enamine chemosensor based on 6-nitro-4-oxo-4H-chromene for ion detection in solution, solid and gas-phase: synthesis, emission, computational and MALDI-TOF-MS studies

On-target ultrasonic digestion of proteins

scientific article

Probe-based chemical modulations of tissues for IMS.

scientific article published on 25 May 2012

Proteogenomics: V international Caparica conference on analytical proteomics. V ICAP-2017

article

Proteomic changes driven by urban pollution suggest particulate matter as a deregulator of energy metabolism, mitochondrial activity, and oxidative pathways in the rat brain

scientific article published on 10 June 2019

Proteomics analysis of the peritoneal dialysate effluent reveals the presence of calcium-regulation proteins and acute inflammatory response

scientific article

Proteomics for Drug Resistance on the Food Chain? Multidrug-Resistant Escherichia coli Proteomes from Slaughtered Pigs

scientific article published in June 2016

Proteomics: The clinical link

scientific article published on 23 February 2012

Revisiting the use of gold and silver functionalised nanoparticles as colorimetric and fluorometric chemosensors for metal ions

Rhodamine-Appended Bipyridine: XOR and OR Logic Operations Integrated in an Example of Controlled Metal Migration

scientific article

S2P: A software tool to quickly carry out reproducible biomedical research projects involving 2D-gel and MALDI-TOF MS protein data.

scientific article

Sensing metal ions with two new azomethine–thiophene pincer ligands (NSN): Fluorescence and MALDI-TOF-MS applications

Snap-heated freeze-free preservation and processing of the urine proteome using the combination of stabilizor-based technology and filter aided sample preparation

scientific article published on 24 May 2019

Study of Multiporphyrin Compounds as Colorimetric Sitting-Atop Metal Complexes: Synthesis and Photophysical Studies

scientific article published on 25 November 2015

Sustainable synthesis of luminescent CdTe quantum dots coated with modified silica mesoporous nanoparticles: Towards new protein scavengers and smart drug delivery carriers

Synthesis of Gold Functionalised Nanoparticles with the Eranthis hyemalis Lectin and Preliminary Toxicological Studies on Caenorhabditis elegans

scientific article published on 06 August 2018

Synthesis of functionalized fluorescent silver nanoparticles and their toxicological effect in aquatic environments (Goldfish) and HEPG2 cells

scientific article published on 05 December 2013

Testing the variability of PSA expression by different human prostate cancer cell lines by means of a new potentiometric device employing molecularly antibody assembled on graphene surface.

scientific article published on 11 November 2015

The aurum sample

scientific article published on 01 June 2015

The confidence of blue: A new highly selective bio-inspired coumarin emissive probe for fluoride recognition

Tissue proteomics and imaging mass spectrometry

scientific article published on 01 April 2014

Toxicokinetics of waterborne trivalent arsenic in the freshwater bivalve Corbicula fluminea.

scientific article published on 23 November 2008

Toxicological effects and bioaccumulation in the freshwater clam (Corbicula fluminea) following exposure to trivalent arsenic

scientific article published on 01 October 2007

Trends in ultrasonic-based equipment for analytical sample treatment.

scientific article published on 26 May 2007

Ultrasonic Energy as a Tool for Sample Treatment for the Analysis of Elements and Elemental Speciation

Ultrasonic multiprobe as a new tool to overcome the bottleneck of throughput in workflows for protein identification relaying on ultrasonic energy

scientific article

Ultrasonic-assisted extraction and digestion of proteins from solid biopsies followed by peptide sequential extraction hyphenated to MALDI-based profiling holds the promise of distinguishing renal oncocytoma from chromophobe renal cell carcinoma

scientific article published on 27 July 2019

Ultrasonic-based membrane aided sample preparation of urine proteomes

scientific article published on 3 October 2017

Unparalleled sample treatment throughput for proteomics workflows relying on ultrasonic energy.

scientific article published on 3 August 2017

Unraveling the Organotellurium Chemistry Applied to the Synthesis of Gold Nanomaterials

scientific article published on 20 December 2016

Untangling interactions of a zinc(II) complex containing a coumarin-porphyrin unit with alkaloids in water solutions: a photophysical study.

scientific article published on April 2015

Use of MALDI-TOF mass spectrometry fingerprinting to characterize Enterococcus spp. and Escherichia coli isolates.

scientific article published on 6 March 2015

List of works by Hugo M. Santos

A comparison of depletion versus equalization for reducing high-abundance proteins in human serum

A comprehensive factorial design study of variables affecting protein extraction from formalin-fixed kidney tissue samples.

A cost-effective method to get insight into the peritoneal dialysate effluent proteome

A journey through PROTEOSONICS.

A mesofluidic platform integrating on-chip probe ultrasonication for multiple sample pretreatment involving denaturation, reduction, and digestion in protein identification assays by mass spectrometry

A methodological approach based on gold-nanoparticles followed by matrix assisted laser desorption ionization time of flight mass spectrometry for the analysis of urine profiling of knee osteoarthritis

A new tripodal poly-imine indole-containing ligand: Synthesis, complexation, spectroscopic and theoretical studies

A novel (18)O inverse labeling-based workflow for accurate bottom-up mass spectrometry quantification of proteins separated by gel electrophoresis

Absolute quantitative proteomics using the total protein approach to identify novel clinical immunohistochemical markers in renal neoplasms

Addendum

An assessment of the indirect high intensity ultrasonic assisted cleavage of complex proteomes with immobilized trypsin.

An assessment of the ultrasonic probe‐based enhancement of protein cleavage with immobilized trypsin ⬇️

An overview on sensing materials depending on the electromagnetic spectra region applied

Analytical Proteomics: An emerging field?

Analytical proteomics. Foreword.

Binding of vanadium to human serum transferrin - voltammetric and spectrometric studies

Bioinspired Functionalized Nanoparticles as Tools for Detection, Quantification and Targeting of Biomolecules

Can sample treatments based on advanced oxidation processes assisted by high-intensity focused ultrasound be used for toxic arsenic determination in human urine by flow-injection hydride-generation atomic absorption spectrometry?

Classifying patients in peritoneal dialysis by mass spectrometry-based profiling

Combined proteomic and metallomic analyses in Scrobicularia plana clams to assess environmental pollution of estuarine ecosystems.

Complete proteome of a quinolone-resistant Salmonella Typhimurium phage type DT104B clinical strain

Could transformation mechanisms of acetylase-harboring pMdT1 plasmid be evaluated through proteomic tools in Escherichia coli?

Decision peptide-driven: a free software tool for accurate protein quantification using gel electrophoresis and matrix assisted laser desorption ionization time of flight mass spectrometry.

Designing Eu-β-diketonate complexes as a support of ionic liquid crystals (ILCs) with additional luminescent properties

Development of a Robust Ultrasonic-Based Sample Treatment To Unravel the Proteome of OCT-Embedded Solid Tumor Biopsies

Development of a fast and efficient ultrasonic-based strategy for DNA fragmentation

Direct matrix assisted laser desorption ionization mass spectrometry-based analysis of wine as a powerful tool for classification purposes

Dithiothreitol-based protein equalization technology to unravel biomarkers for bladder cancer

Editorial: Rational Design of Multi-Functional Nanomaterials

Effect of vancomycin on the proteome of the multiresistant Enterococcus faecium SU18 strain

Evaluation of the binding of four anti-tumor Casiopeínas® to human serum albumin

Exploiting anionic and cationic interactions with a new emissive imine-based β-naphthol molecular probe

Fast human serum profiling through chemical depletion coupled to gold-nanoparticle-assisted protein separation

Foreword for special issue splicing 2016.

Foreword ultrasonics 2016 special issue

From colorimetric chemosensors to metal nanoparticles using two new tyrosine Schiff-base ligands for Cu2+ detection

From visible to far-red excitable chromophores derivatives of vitamin B6. Evaluation as pH-responsive probes and solvatochromic study

Front Cover: Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual‐Color Flag (ChemistryOpen 1/2018).

Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual-Color Flag

Green and Red Fluorescent Dyes for Translational Applications in Imaging and Sensing Analytes: A Dual-Color Flag.

Improving sample treatment for in-solution protein identification by peptide mass fingerprint using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Interaction of [VIV O(acac)2 ] with Human Serum Transferrin and Albumin

Label-free protein quantification after ultrafast digestion of complex proteomes using ultrasonic energy and immobilized-trypsin magnetic nanoparticles

Latest developments in sample treatment for 18O-isotopic labeling for proteomics mass spectrometry-based approaches: a critical review.

Light and colour as analytical detection tools: a journey into the periodic table using polyamines to bio-inspired systems as chemosensors

Mass Spectrometry-based Proteomics: What is it expecting ahead?

Mass-Up: an all-in-one open software application for MALDI-TOF mass spectrometry knowledge discovery.

Metallothionein responses in the Asiatic clam (Corbicula fluminea) after exposure to trivalent arsenic

Modulating the protein content of complex proteomes using acetonitrile.

Multiomics Assessment of Gene Expression in a Clinical Strain of CTX-M-15-Producing ST131 Escherichia coli

New chemosensors based on thiomacrocycle-containing coumarin-343 fluoroionophor: X-ray structures and previous results on the effect of cation binding on the photophysical properties

New emissive dopamine derivatives as fluorescent chemosensors for metal ions: A CHEF effect for Al(III) interaction

Novel nanocomposites based on a strawberry-like gold- coated magnetite (Fe@Au) for protein separation in multiple myeloma serum samples

Novel versatile imine—enamine chemosensor based on 6-nitro-4-oxo-4H-chromene for ion detection in solution, solid and gas-phase: synthesis, emission, computational and MALDI-TOF-MS studies

On-target ultrasonic digestion of proteins

Probe-based chemical modulations of tissues for IMS.

Proteogenomics: V international Caparica conference on analytical proteomics. V ICAP-2017

Proteomic changes driven by urban pollution suggest particulate matter as a deregulator of energy metabolism, mitochondrial activity, and oxidative pathways in the rat brain

Proteomics analysis of the peritoneal dialysate effluent reveals the presence of calcium-regulation proteins and acute inflammatory response

Proteomics for Drug Resistance on the Food Chain? Multidrug-Resistant Escherichia coli Proteomes from Slaughtered Pigs

Proteomics: The clinical link

Revisiting the use of gold and silver functionalised nanoparticles as colorimetric and fluorometric chemosensors for metal ions

Rhodamine-Appended Bipyridine: XOR and OR Logic Operations Integrated in an Example of Controlled Metal Migration

S2P: A software tool to quickly carry out reproducible biomedical research projects involving 2D-gel and MALDI-TOF MS protein data.

Sensing metal ions with two new azomethine–thiophene pincer ligands (NSN): Fluorescence and MALDI-TOF-MS applications

Snap-heated freeze-free preservation and processing of the urine proteome using the combination of stabilizor-based technology and filter aided sample preparation

Study of Multiporphyrin Compounds as Colorimetric Sitting-Atop Metal Complexes: Synthesis and Photophysical Studies

Sustainable synthesis of luminescent CdTe quantum dots coated with modified silica mesoporous nanoparticles: Towards new protein scavengers and smart drug delivery carriers

Synthesis of Gold Functionalised Nanoparticles with the Eranthis hyemalis Lectin and Preliminary Toxicological Studies on Caenorhabditis elegans

Synthesis of functionalized fluorescent silver nanoparticles and their toxicological effect in aquatic environments (Goldfish) and HEPG2 cells

Testing the variability of PSA expression by different human prostate cancer cell lines by means of a new potentiometric device employing molecularly antibody assembled on graphene surface.

The aurum sample

The confidence of blue: A new highly selective bio-inspired coumarin emissive probe for fluoride recognition

Tissue proteomics and imaging mass spectrometry

Toxicokinetics of waterborne trivalent arsenic in the freshwater bivalve Corbicula fluminea.

Toxicological effects and bioaccumulation in the freshwater clam (Corbicula fluminea) following exposure to trivalent arsenic

Trends in ultrasonic-based equipment for analytical sample treatment.

Ultrasonic Energy as a Tool for Sample Treatment for the Analysis of Elements and Elemental Speciation

Ultrasonic multiprobe as a new tool to overcome the bottleneck of throughput in workflows for protein identification relaying on ultrasonic energy