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Authors whose works are in public domain in at least one jurisdiction

List of works by Allen D. Roses

A Bgl II polymorphism detected by LDR152 [D19S19].

scientific article published on September 1988

A Genetics-based Biomarker Risk Algorithm for Predicting Risk of Alzheimer's Disease.

scientific article published on January 2016

A PvuII polymorphism detected by pEW404 (D17S64) on chromosome 17.

scientific article

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

scientific article

A comparison of neuropsychological performance between US and Russia: preparing for a global clinical trial

scientific article

A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group

scientific article published on 01 August 1996

A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression.

scientific article

A de novo frame-shift mutation in the tuberin gene ⬇️

scientific article published on August 1, 1995

A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.

scientific article published on 4 December 2012

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

scientific article

A genome-wide investigation of SNPs and CNVs in schizophrenia

scientific article

A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study

scientific article

A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging

scientific article

A molecular genetic study of intracerebral hemorrhage

scientific article published on 01 October 1994

A new human slow skeletal troponin T (TnTs) mRNA isoform derived from alternative splicing of a single gene

scientific article published on March 1994

A new tightly linked DNA probe for myotonic dystrophy

scientific article published on 01 August 1986

A novel splice site mutation (156 + 1G-->A) in the TSC2 gene

scientific article published on 01 January 1997

A polymorphic DNA sequence (174-3.7) on chromosome 19 [D19S58].

scientific article published on December 1989

A prospective study of thymectomy and serum acetylcholine receptor antibodies in myasthenia gravis

scientific article published on 01 August 1982

A roadmap for the prevention of dementia II: Leon Thal Symposium 2008.

scientific article published on March 2009

A single-nucleotide polymorphism tagging set for human drug metabolism and transport

scientific article published on 19 December 2004

A triplet repeat polymorphism in a gene expressed in human hypothalamus

scientific article published in August 1993

AChR antibody titer and clinical response to thymectomy in MG

scientific article published on 01 July 1984

APOE is a major susceptibility gene for Alzheimer's disease

scientific article published on December 1994

APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans

scientific article

APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds

scientific article published on 26 August 2015

African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles.

scientific article published on 26 September 2014

Age at onset in two common neurodegenerative diseases is genetically controlled

scientific article published on March 2002

Age-related congophilic inclusions in the brains of apolipoprotein E-deficient mice.

scientific article published in January 1998

Alzheimer's disease susceptibility genes APOE and TOMM40, and brain white matter integrity in the Lothian Birth Cohort 1936.

scientific article published on 08 January 2014

Alzheimer's disease susceptibility genes APOE and TOMM40, and hippocampal volumes in the Lothian birth cohort 1936.

scientific article

Alzheimer’s disease: diagnostics, prognostics and the road to prevention ⬇️

scientific article published on June 29, 2010

Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease

scientific article published on May 1998

An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease

scientific article published in May 1999

An epidemiologic-based survey of public attitudes towards predictive genetic testing in Russia

scientific article published on 01 May 2010

Analysis of European mitochondrial haplogroups with Alzheimer disease risk

scientific article

Analysis of association at single nucleotide polymorphisms in the APOE region

scientific article published in January 2000

Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K)

scientific article published on 01 July 1999

Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy

scientific article published in Nature

ApoE, Alzheimer's Disease, and Recovery from Brain Stressa ⬇️

scientific article published on September 26, 1997

ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylation

scientific article

ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory

scientific article published in August 2003

Apolipoprotein E E4 allele and risk of dementia

scientific article published in February 1995

Apolipoprotein E Genotyping as a Diagnostic Adjunct for Alzheimer's Disease ⬇️

scientific article published on 01 January 1997

Apolipoprotein E Isoform-Specific Differences in Outcome from Focal Ischemia in Transgenic Mice ⬇️

scientific article published on April 1, 1998

Apolipoprotein E Uptake and Low-Density Lipoprotein Receptor-Related Protein Expression by the NTera2/D1 Cell Line: A Cell Culture Model of Relevance for Late-Onset Alzheimer's Disease ⬇️

scientific article published on January 1, 1997

Apolipoprotein E alleles in sporadic inclusion-body myositis and hereditary inclusion-body myopathy

scientific article published on 01 August 1996

Apolipoprotein E and Alzheimer disease

scientific article

Apolipoprotein E and Alzheimer's disease

scientific article published on 01 January 1996

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

scientific article

Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease

scientific article published in September 1997

Apolipoprotein E genotype and Lewy body disease

scientific article published on 01 January 1995

Apolipoprotein E genotypes in a neuropathological series from the consortium to establish a registry for Alzheimer's disease ⬇️

scientific article published on September 1, 1997

Apolipoprotein E in Creutzfeldt-Jacob disease

Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study

scientific article

Apolipoprotein E is present in hippocampal neurons without neurofibrillary tangles in Alzheimer's disease and in age-matched controls

scientific article published in July 1994

Apolipoprotein E-Deficient Mice Have Increased Susceptibility To Focal Cerebral Ischemia ⬇️

scientific article published on July 1, 1997

Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype

scientific article published in February 1997

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

scientific article

Are APOE ɛ genotype and TOMM40 poly-T repeat length associations with cognitive ageing mediated by brain white matter tract integrity?

scientific article

Assignment of the human slow skeletal troponin T gene to 19q13.4 using somatic cell hybrids and fluorescence in situ hybridization analysis

scientific article

Association between bleomycin hydrolase and Alzheimer's disease in caucasians

scientific article published in November 1998

Association of Single-Nucleotide Polymorphisms of the Tau Gene With Late-Onset Parkinson Disease ⬇️

scientific article published on November 14, 2001

Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations

scientific article published in March 2004

Autologous mixed lymphocyte reaction in patients with myasthenia gravis: correlation with disease activity ⬇️

scientific article published on 01 March 1984

Avid binding of beta A amyloid peptide to its own precursor

scientific article published on 01 August 1993

Beta-amyloid protein-containing inclusions in skeletal muscle of apolipoprotein-E-deficient mice

scientific article published on February 1997

Binding of IgG to amyloid beta A4 peptide via the heavy-chain hinge region with preservation of antigen binding

scientific article published on 01 November 1993

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

scientific article

Blood glucose levels and cortical thinning in cognitively normal, middle-aged adults

scientific article published on 14 April 2016

CAP--advancing the evaluation of preclinical Alzheimer disease treatments

scientific article published on 29 September 2015

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

scientific article

Cardiac involvement in myotonic muscular dystrophy

scientific article published in November 1985

Cellular localization of messenger RNA encoding amyloid-beta-protein in normal tissue and in Alzheimer disease

scientific article

Cerebral metabolic and cognitive decline in persons at genetic risk for Alzheimer's disease

scholarly article

Characterization of APOE and TOMM40 allele frequencies in the Japanese population

scientific article published on 6 September 2017

Characterization of amyloid fibril beta-peptide in familial Alzheimer's disease with APP717 mutations

scientific article published in December 1993

Characterization of the poly-T variant in the TOMM40 gene in diverse populations

scientific article (publication date: 2012)

Chorea-acanthocytosis: a report of three new families and implications for genetic counselling

scientific article

Cis-Acting Human ApoE Tissue Expression Element is Associated with Human Pattern of Intraneuronal ApoE in Transgenic Mice ⬇️

scientific article published on January 1, 1998

Clinical and genetic investigation in autosomal dominant limb-girdle muscular dystrophy

scientific article published on 01 January 1988

Clinical application of apolipoprotein E genotyping to Alzheimer's disease

scientific article published in June 1994

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease ⬇️

scientific article published on June 29, 1995

Clusters of adjacent and similarly expressed genes across normal human tissues complicate comparative transcriptomic discovery

scientific article published on 01 January 2005

Community engagement in diverse populations for Alzheimer disease prevention trials.

scientific article

Complete genomic screen in Parkinson disease: evidence for multiple genes

scientific article

Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.

scientific article published in October 1997

Complete genomic screen in late-onset familial Alzheimer's disease

scientific article published in January 1998

Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease).

scientific article published on 13 June 2006

Complex genetic disease: can genetic strategies in Alzheimer's disease and new genetic mechanisms be applied to epilepsy?

scientific article published on January 1994

Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease

scientific article

Confirmation of linkage in von Hippel-Lindau disease

scientific article published on 01 March 1990

Confirmation of linkage of oculopharyngeal muscular dystrophy to chromosome 14q11.2-q13

scientific article published on 01 November 1996

Confirmation of linkage of oculopharyngeal muscular dystrophy to chromosome 14q11.2-q13 in American families suggests the existence of a second causal mutation

scientific article published on 01 October 1997

Correction: A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia

Corrigendum to "The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer's disease" [Biochim. Biophys. Acta 1863/11 (2017) 2973-2986].

scientific article published on 27 January 2018

Cystatin C mutation in an elderly man with sporadic amyloid angiopathy and intracerebral hemorrhage

scientific article published on 01 November 1995

D2 dopamine receptor A1 allele in Alzheimer disease and aging

scientific article

Defective neuronal sprouting by human apolipoprotein E4 is a gain-of-negative function

scientific article published in May 2002

Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs

scientific article published in July 1995

Design of the Genetics of Early Onset Cardiovascular Disease (GENECARD) study

scientific article published in April 2003

Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment

scientific article

Developing a national strategy to prevent dementia: Leon Thal Symposium 2009.

scientific article

Development of a microsatellite genetic map spanning 5q31–q33 and subsequent placement of the LGMD1A locus between D5S178 and IL9

article

Disease-modifying effects of an SCAF4 structural variant in a predominantly SOD1 ALS cohort

scientific article published on 01 July 2020

Disease-specific target selection: a critical first step down the right road

scientific article

Duchenne muscular dystrophy: detection of deletion carriers by spectrophotometric densitometry

scientific article published on 01 June 1989

Early detection of Alzheimer's disease by combining apolipoprotein E and neuroimaging.

scientific article published in December 1996

Effect of sera from myasthenia gravis patients on acetylcholine receptors in myotube cultures

scientific article published on 01 April 1983

Effects of low doses of pioglitazone on resting-state functional connectivity in conscious rat brain

scientific article

Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

scientific article

Electrocardiographic abnormalities in carriers of Duchenne muscular dystrophy

scientific article published on 01 May 1980

Endoglin gene polymorphism as a risk factor for sporadic intracerebral hemorrhage

scientific article published on 01 May 1997

Evaluation of suspected dementia

scientific article published on 01 December 1996

Evidence for linkage disequilibrium in chromosome 13-linked Duchenne-like muscular dystrophy (LGMD2C)

scientific article

Exclusion mapping of chromosomal regions which cross hybridise to FSHD1A associated markers in FSHD1B

scientific article (publication date: October 1995)

Expression of alpha-3, alpha-5, and beta-4 neuronal acetylcholine receptor subunit transcripts in normal and myasthenia gravis thymus. Identification of thymocytes expressing the alpha-3 transcripts

scientific article published on 01 December 1993

Failure to replicate effect of Kibra on human memory in two large cohorts of European origin

scientific article

Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway

scientific article published in February 1996

Familial inheritance of a DXS164 deletion mutation from a heterozygous female

scientific article

Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts

scientific article published on 10 May 2017

Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: potential genetic and phenotypic heterogeneity

scientific article

Further evidence linking late-onset Alzheimer disease with chromosome 12.

scientific article published in February 1999

Further exclusion of FSHD1B from the telomeric region of 10q

scientific article (publication date: September 1997)

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

scientific article (publication date: 13 August 1993)

Genetic linkage analysis of nerve growth factor (beta) in familial alzheimer's disease ⬇️

scientific article published on August 1, 1991

Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease

scientific article published on 01 April 2003

Genetic studies in Alzheimer's disease with an NACP/alpha-synuclein polymorphism

scientific article published in August 1996

Genetic variation at a single locus and age of onset for Alzheimer's disease.

scientific article

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir

scientific article (publication date: 30 March 2002)

Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions

scientific article published on 26 February 2008

Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry

scientific journal article

Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts

scholarly article by P Muglia et al published 23 December 2008 in Molecular Psychiatry

Genome-wide scan of copy number variation in late-onset Alzheimer's disease

scientific article

Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease

scientific article (publication date: 15 December 2003)

Golden retriever muscular dystrophy: monitoring for success

scientific article published in January 1990

Healthy aging and preclinical dementia: the United States-Israel Longitudinal Database project

scientific article published in November 2010

Hereditary motor and sensory neuropathy, X-linked: a half century follow-up

scientific article published on 01 September 1987

Human apoE3 but not apoE4 rescues impaired astrocyte activation in apoE null mice

scientific article published in February 2003

Human apolipoprotein E accelerates microtubule polymerization in vitro ⬇️

scientific article published on April 3, 1998

Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture

scientific article published on December 1999

Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

scientific article published on January 1996

Human endopeptidase (THOP1) is localized on chromosome 19 within the linkage region for the late-onset alzheimer disease AD2 locus

scientific article

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

scientific article published in March 1996

Identification of Novel Genes in Late-Onset Alzheimer's Disease

article

Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map.

scientific article

Identification of abnormally [32P]-phosphorylated cyanogen bromide cleavage product of erythrocyte membrane spectrin in Duchenne muscular dystrophy

scientific article published in August 1981

Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways

article

Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways

scientific article

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

scientific article published on October 1993

Influence of the susceptibility genes apolipoprotein E-epsilon 4 and apolipoprotein E-epsilon 2 on the rate of disease expressivity of late-onset Alzheimer's disease

scientific article published on March 1995

Inhibition of α-ketoglutarate-and pyruvate dehydrogenase complexes in E. coli by a glutathione S-transferase containing a pathological length poly-Q domain: A possible role of energy deficit in neurological diseases associated with poly-Q expansions

scientific article published on 01 January 1998

Intraneuronal ApoE in human visual cortical areas reflects the staging of Alzheimer disease pathology

scientific article published in December 1998

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

scientific article

Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease

scientific article published in November 1994

Isolation and localization of a slow troponin (TnT) gene on chromosome 19 by subtraction hybridization of a cDNA muscle library using myotonic dystrophy muscle cDNA ⬇️

scientific article published on December 1, 1990

Isolation of a cytochrome oxidase gene overexpressed in Alzheimer's disease brain

scientific article

Lack of association of very low density lipoprotein receptor gene polymorphism with Caucasian Alzheimer's disease

scientific article published in August 1996

Linkage analysis in familial Alzheimer disease: description of the Duke and Boston data sets.

scientific article published on January 1993

Linkage analysis in the spinal muscular atrophy type of facioscapulohumeral disease.

scientific article

Linkage analysis of peripheral neurofibromatosis to DNA markers on chromosome 8.

scientific article

Linkage of Charcot-Marie-Tooth neuropathy type 1a to chromosome 17

scientific article published on 01 May 1989

Linkage of Tunisian autosomal recessive Duchenne-like muscular dystrophy to the pericentromeric region of chromosome 13q.

scientific article

Linkage of a locus (CMT4A) for autosomal recessive Charcot-Marie-Tooth disease to chromosome 8q.

scientific article

Linkage of frontotemporal dementia to chromosome 17: clinical and neuropathological characterization of phenotype

scientific article published in December 1996

Linkage studies in Charcot-Marie-Tooth disease type 2: evidence that CMT types 1 and 2 are distinct genetic entities

scientific article published on 01 March 1992

Linkage studies in familial Alzheimer's disease

scientific article published in January 1989

Linkage studies in peripheral neurofibromatosis.

scientific article

Linkage studies in tuberous sclerosis. Chromosome 9?, 11?, or maybe 14!

scientific article published on January 1991

Linkage studies of late-onset familial Alzheimer's disease

scientific article published in January 1990

Localization of Charcot-Marie-Tooth disease type 1a (CMT1A) to chromosome 17p11.2.

scientific article published in April 1991

Localization of a Gene (CMT2A) for Autosomal Dominant Charcot-Marie-Tooth Disease Type 2 to Chromosome 1p and Evidence of Genetic Heterogeneity

article

Localization of cloned unique DNA to three different regions of chromosome 19: screen for linkage probes for myotonic dystrophy

scientific article

Localization of neuron-specific enolase (NSE) mRNA in human brain

scientific article published on 01 May 1987

Longitudinal modeling of cognitive aging and the TOMM40 effect

scientific article

Medical applications of haplotype-based SNP maps: learning to walk before we run.

scientific article published in November 2002

Memory self-appraisal in middle-aged and older adults with the apolipoprotein E-4 allele.

scientific article published on July 1999

Molecular markers for myoblast transplantation in GRMD

scientific article published on 01 January 1990

Morphological, Biochemical, and Genetic Support for an Apolipoprotein E Effect on Microtubular Metabolisma

scientific article (publication date: 1996)

Morphological, biochemical, and genetic support for an apolipoprotein E effect on microtubular metabolism

scientific article

Mutation analysis of the TSC2 gene in an African-American family

scientific article published in December 1995

Mutation and polymorphism analysis in the tuberous sclerosis 2 (TSC2) gene

scientific article published on 01 August 1998

Myotonic dystrophy: update on progress to define the gene.

scientific article

Myotonic muscular dystrophy. Calcium-dependent phosphatidate metabolism in the erythrocyte membrane

scientific article published in May 1982

Myotonic muscular dystrophy: morphology, histochemistry, and growth characteristics of cultured skin fibroblasts

scientific article published on 01 February 1982

Neonatal myasthenia gravis in the infant of an asymptomatic thymectomized mother

scientific article published on 01 May 1982

Neurodegeneration in the central nervous system of apoE-deficient mice

scientific article published in December 1995

Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684.

scientific article published in August 1999

New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics

scientific article published on May 2016

New applications of disease genetics and pharmacogenetics to drug development.

scientific article published on 03 January 2014

Nicotinic neuronal acetylcholine receptor alpha-3 subunit transcription in normal and myasthenic thymus

scientific article published on 01 June 1993

No association between alpha 1-antichymotrypsin and familial Alzheimer's disease

scientific article published in December 1996

No association between the HLA-A2 allele and Alzheimer disease.

scientific article published on September 1999

No association between very low density lipoprotein receptor (VLDL-R) and Alzheimer disease in American Caucasians

scientific article published in May 1996

No association of alpha1-antichymotrypsin flanking region polymorphism and Alzheimer disease risk in early- and late-onset Alzheimer disease patients

scientific article

No direct correlation between serum antiacetylcholine receptor antibody levels and clinical state of individual patients with myasthenia gravis

scientific article published on 01 February 1981

No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease

scientific article published in March 1998

No genetic effect of alpha1-antichymotrypsin in Alzheimer disease

scientific article published in April 1996

Novel Large Apolipoprotein E‐Containing Lipoproteins of Density 1.006–1.060 g/ml in Human Cerebrospinal Fluid ⬇️

scientific article published on March 1, 1998

O3-02-07: Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways

scholarly article by Jill C. Richardson et al published July 2008 in Alzheimer's and Dementia

Oligomerization of expanded-polyglutamine domain fluorescent fusion proteins in cultured mammalian cells

scientific article published on 01 September 1997

On the utility of data from the International HapMap Project for Australian association studies.

scientific article

Ordered-subsets linkage analysis detects novel Alzheimer disease loci on chromosomes 2q34 and 15q22.

scientific article

Patients with myotonic dystrophy, a possible segmental progeroid syndrome, and Duchenne muscular dystrophy have fibroblasts with normal limits for in vitro lifespan and growth characteristics

scientific article published on 01 May 1981

Perspective on a pathogenesis and treatment of Alzheimer's disease

scientific article

Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility

scientific article published on 11 March 2008

Physical and Genetic Mapping of the CMT4A Locus and Exclusion of PMP-2 as the Defect in CMT4A

scientific article published on 01 July 1995

Pipeline pharmacogenetics: a novel approach to integrating pharmaco-genetics into drug development

scientific article published on January 2009

Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection

scientific article published on 17 August 2012

Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases?

scientific article published in July 1997

Polymorphism in the TOMM40 gene modifies the risk of developing sporadic inclusion body myositis and the age of onset of symptoms ⬇️

scientific article published on September 19, 2013

Polymorphisms in the endothelin-1 (EDN1) are associated with asthma in two populations

scientific article published on 25 October 2007

Prediction for unimpaired subjects is different from diagnosis of demented patients

scientific article published in March 1997

Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center

scientific article published in September 1997

Prenatal diagnosis using deletion studies in Duchenne muscular dystrophy

scientific article published on 01 July 1988

Presenilin-1 polymorphism and Alzheimer's disease

scientific article published on 01 April 1996

Presenilin-1 polymorphism and Alzheimer's disease

scientific article published on 01 June 1996

Presymptomatic and prenatal diagnosis in myotonic dystrophy by genetic linkage studies

scientific article published on 01 April 1990

Promiscuous expression of myosin in myotonic dystrophy

scientific article published on 01 May 1986

Protein: protein interactions in Alzheimer's disease and the CAG triplet repeat diseases

scientific article published on January 1, 1996

Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations

scientific article

Proteomic identification and early validation of complement 1 inhibitor and pigment epithelium-derived factor: Two novel biomarkers of Alzheimer's disease in human plasma.

scientific article

RFLP for Duchenne muscular dystrophy cDNA clone 30-2.

scientific article published on September 1988

RFLP for Duchenne muscular dystrophy cDNA clone 44-1.

scientific article published on July 1988

RFLPs at the D19S19 locus of human chromosome 19 linked to myotonic dystrophy (DM).

scientific article

RFLPs of the gene for the human glycine receptor on the X-chromosome

scientific article published on February 1989

Rapid brain autopsy. The Joseph and Kathleen Bryan Alzheimer's Disease Research Center experience.

scientific article published in June 1997

Recombinant DNA strategies in genetic neurological diseases

scientific article published on June 1983

Recombination of 4p16 DNA markers in an unusual family with Huntington disease.

scientific article

Regionally specific neuronal expression of human APOE gene in transgenic mice ⬇️

scientific article published on April 24, 1998

Reply to 'Haplotype block structure of the cytochrome P450 CYP2C gene cluster on chromosome 10'

article

Reply to “A role for GAPDH in apoptosis and neurodegeneration”

Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study

scientific article

Risky apolipoprotein in brain

scientific article published in Nature

Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons

scientific article

Rosiglitazone induces mitochondrial biogenesis in mouse brain.

scientific article

SNPing away at complex diseases: analysis of single-nucleotide polymorphisms around APOE in Alzheimer disease

scientific article

Sequestration of amyloid beta-peptide

scientific article

Sialylated human apolipoprotein E (apoEs) is preferentially associated with neuron-enriched cultures from APOE transgenic mice

scientific article published in February 1999

Sib-pair linkage analysis in late onset Alzheimer's disease

scientific article published in January 1989

Single-Nucleotide Polymorphism Alleles in the Insulin Receptor Gene Are Associated with Typical Migraine

scientific article published in February 2002

Splicing of an anti-sense Alu sequence generates a coding sequence variant for the alpha-3 subunit of a neuronal acetylcholine receptor

scientific article published in November 1993

Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing

scientific article published on 04 January 2016

TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial.

scientific article published on 18 January 2013

TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype

scientific article published on 20 January 2017

The Alu neurodegeneration hypothesis: A primate-specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease.

scientific article

The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer's disease.

scientific article

The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging

scientific article

The Haw River syndrome: dentatorubropallidoluysian atrophy (DRPLA) in an African-American family

scientific article (publication date: August 1994)

The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research

scientific article published on 28 August 2008

The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease

scientific article published in August 2003

The Role of Upregulated APOE in Alzheimer's Disease Etiology

scientific article published on 9 February 2016

The SSV Evaluation System: A Tool to Prioritize Short Structural Variants for Studies of Possible Regulatory and Causal Variants

scientific article published on 9 June 2016

The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes

scientific article published on 13 June 2014

The apolipoprotein E E4 allele and sex-specific risk of Alzheimer's disease

scientific article published in February 1995

The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes

scientific article

The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective

scientific article published on March 1997

The discovery and early validation of novel plasma biomarkers in mild-to-moderate Alzheimer's disease patients responding to treatment with rosiglitazone

scientific article published on 01 September 2008

The effect of TOMM40 poly‐T length on gray matter volume and cognition in middle‐aged persons with APOEɛ3/ɛ3 genotype ⬇️

scientific article published on July 1, 2011

The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster

scientific article published on 5 January 2017

The genetic contributions of SNCA and LRRK2 genes to Lewy Body pathology in Alzheimer's disease

scientific article

The human NACP/α-synuclein gene: chromosome assignment to 4q21.3–q22 and TaqI RFLP analysis ⬇️

scientific article published on March 20, 1995

The importance of being connected

scientific article published in January 2011

The knockout mouse project

scientific article

The molecular genetic revolution. Its impact on clinical neurology

scientific article published on December 1988

The poliovirus sensitivity (PVS) gene is on chromosome 19q12----q13.2.

scientific article published on 01 August 1988

The role of apolipoprotein E in Alzheimer's disease: pharmacogenomic target selection

scientific article

The role of apolipoprotein E in the nervous system.

scientific article published on April 1994

There is a pathologic relationship between ApoE-epsilon 4 and Alzheimer's disease

scientific article published on 01 July 1995

Thymectomy as primary therapy in myasthenia gravis

scientific article published on 01 January 1987

Thymectomy in late-onset myasthenia gravis

scientific article published on 01 February 1982

Thymocytes and cultured thymic epithelial cells express transcripts encoding alpha-3, alpha-5, and beta-4 subunits of neuronal nicotinic acetylcholine receptors. Preferential transcription of the alpha-3 and beta-4 genes by immature CD4+8+ thymocyte

scientific article published in May 1998

Thymocytes and cultured thymic epithelial cells express transcripts encoding α-3, α-5 and β-4 subunits of neuronal nicotinic acetylcholine receptors: preferential transcription of the α-3 and β-4 genes by immature CD4+8+ thymocytes ⬇️

scientific article published on 01 November 1997

Toxicity of expanded polyglutamine-domain proteins in Escherichia coli

scientific article

Transglutaminase-catalyzed inactivation of glyceraldehyde 3-phosphate dehydrogenase and alpha-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length

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X-linked neuropathy: gene localization with DNA probes

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