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List of works by Graham C. Walker

A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase.

scientific article

A LuxR homolog controls production of symbiotically active extracellular polysaccharide II by Sinorhizobium meliloti

scientific article

A chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivo

scientific article (publication date: 2014)

A highly conserved protein of unknown function in Sinorhizobium meliloti affects sRNA regulation similar to Hfq. ⬇️

scientific article

A highly conserved protein of unknown function is required by Sinorhizobium meliloti for symbiosis and environmental stress protection.

scientific article

A novel exopolysaccharide can function in place of the Calcofluor-binding exopolysaccharide in nodulation of alfalfa by Rhizobium meliloti

scientific article published in February 1989

A role for the umuDC gene products of Escherichia coli in increasing resistance to DNA damage in stationary phase by inhibiting the transition to exponential growth

scientific article

A single amino acid governs enhanced activity of DinB DNA polymerases on damaged templates.

scientific article published in January 2006

A small-scale concept-based laboratory component: the best of both worlds.

scientific article published on January 2006

ATPase-defective derivatives of Escherichia coli DnaK that behave differently with respect to ATP-induced conformational change and peptide release

scientific article

Active site residues critical for flavin binding and 5,6-dimethylbenzimidazole biosynthesis in the flavin destructase enzyme BluB.

scientific article published on 23 April 2012

Alfalfa root nodule invasion efficiency is dependent on Sinorhizobium meliloti polysaccharides

scientific article published in August 2000

Alternative exon splicing controls a translational switch from activator to repressor isoforms of transcription factor CREB during spermatogenesis.

scientific article

Analysis of mRNA synthesis following induction of the Escherichia coli SOS system

scientific article published on 01 September 1984

Antibiotics induce redox-related physiological alterations as part of their lethality.

scientific article

BacA, an ABC transporter involved in maintenance of chronic murine infections with Mycobacterium tuberculosis

scientific article

BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

scientific article

Beta clamp directs localization of mismatch repair in Bacillus subtilis

scientific article published on February 2008

Biological cost of pyocin production during the SOS response in Pseudomonas aeruginosa.

scientific article

Biosynthesis of succinoglycan, a symbiotically important exopolysaccharide of Rhizobium meliloti

scientific article published on 01 July 1993

Biotin labeling of the symbiotically important succinoglycan oligosaccharides of Rhizobium meliloti for identification of putative plant receptors.

scientific article published in June 2001

BluB cannibalizes flavin to form the lower ligand of vitamin B12

scientific article

Brucella abortus bacA mutant induces greater pro-inflammatory cytokines than the wild-type parent strain

scientific article published on 11 December 2006

Bryn Bridges and mutagenesis: exploring the intellectual space.

scientific article published in February 2001

CbrA is a stationary-phase regulator of cell surface physiology and legume symbiosis in Sinorhizobium meliloti.

scientific article

Cell Cycle Control by the Master Regulator CtrA in Sinorhizobium meliloti.

scientific article published on 15 May 2015

Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria.

scientific article

Changing the Culture of Science Education at Research Universities

scientific article published in Science

Characterization of Escherichia coli translesion synthesis polymerases and their accessory factors.

scientific article

Characterization of a novel pyranopyridine inhibitor of the AcrAB efflux pump of Escherichia coli

scientific article

Characterization of novel alleles of the Escherichia coli umuDC genes identifies additional interaction sites of UmuC with the beta clamp.

scientific article published on 24 July 2009

Clp and Lon proteases occupy distinct subcellular positions in Bacillus subtilis.

scientific article published on 08 August 2008

Comparison of responses to double-strand breaks between Escherichia coli and Bacillus subtilis reveals different requirements for SOS induction

scientific article published on 05 December 2008

Competencies: A Cure for Pre-Med Curriculum

scientific article published on 01 November 2011

Complementation of a pKM101 derivative that decreases resistance to UV killing but increases susceptibility to mutagenesis.

scientific article published in June 1985

Conserved bacterial RNase YbeY plays key roles in 70S ribosome quality control and 16S rRNA maturation

scientific article published on 27 December 2012

DNA polymerase V allows bypass of toxic guanine oxidation products in vivo.

scientific article published on 24 February 2007

DNA repair and mutagenesis ⬇️

book

Deficiency of a Sinorhizobium meliloti BacA mutant in alfalfa symbiosis correlates with alteration of the cell envelope

scientific article

Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair

scientific article published in 2022

Differential cleavage of LexA and UmuD mediated by recA Pro67 mutants: implications for common LexA and UmuD binding sites on RecA

scientific article published on 01 February 1998

Differential response of the plant Medicago truncatula to its symbiont Sinorhizobium meliloti or an exopolysaccharide-deficient mutant

scholarly article

Disruption of sitA compromises Sinorhizobium meliloti for manganese uptake required for protection against oxidative stress

scientific article published on 15 December 2006

Effect of o-acyl substituents on the functional behaviour of Rhizobium meliloti succinoglycan

scientific article published on 01 February 1997

Efficient extension of slipped DNA intermediates by DinB is required to escape primer template realignment by DnaQ.

scientific article

Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug.

scientific article published on 28 October 2013

Enteric YaiW is a surface-exposed outer membrane lipoprotein that affects sensitivity to an antimicrobial peptide.

scientific article

Essential role for the BacA protein in the uptake of a truncated eukaryotic peptide in Sinorhizobium meliloti

scientific article published on 12 December 2008

Eukaryotic translesion polymerases and their roles and regulation in DNA damage tolerance

scientific article

Exo-oligosaccharides of Rhizobium sp. strain NGR234 are required for symbiosis with various legumes

scientific article

Exopolysaccharides of Rhizobium: synthesis, regulation and symbiotic function

scientific article published on 01 February 1994

Functional characterization of bacterial sRNAs using a network biology approach ⬇️

scientific article published on August 29, 2011

Genetic analysis of the Sinorhizobium meliloti BacA protein: differential effects of mutations on phenotypes.

scientific article

Genetic and biochemical characterization of a novel umuD mutation: insights into a mechanism for UmuD self-cleavage

scientific article

Genetic interactions between the Escherichia coli umuDC gene products and the beta processivity clamp of the replicative DNA polymerase.

scientific article

Global analysis of cell cycle gene expression of the legume symbiont Sinorhizobium meliloti.

scientific article published on 05 February 2014

Host plant peptides elicit a transcriptional response to control the Sinorhizobium meliloti cell cycle during symbiosis.

scientific article published on 05 February 2014

How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model

scientific article

Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.

scientific article

Identification of novel Sinorhizobium meliloti mutants compromised for oxidative stress protection and symbiosis

scientific article published on 15 December 2006

Identification of the Rhizobium meliloti alcohol dehydrogenase gene (adhA) and heterologous expression in Alcaligenes eutrophus

scientific article published on 01 May 1998

Importance of unusually modified lipid A in Sinorhizobium stress resistance and legume symbiosis.

scientific article published in April 2005

Inferences concerning the ATPase properties of DnaK and other HSP70s are affected by the ADP kinase activity of copurifying nucleoside-diphosphate kinase.

scientific article published in December 1999

Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy?

scientific article published on 17 August 2017

Interactions of Peptides with DnaK and C-Terminal DnaK Fragments Studied Using Fluorescent and Radioactive Peptides ⬇️

scientific article published on August 15, 1998

Interrelations between glycine betaine catabolism and methionine biosynthesis in Sinorhizobium meliloti strain 102F34

scientific article

Lighting torches in the DNA repair field: development of key concepts.

scientific article

Localization of UvrA and effect of DNA damage on the chromosome of Bacillus subtilis.

scientific article

Localization of the plasmid (pKM101) gene(s) involved in recA+lexA+-dependent mutagenesis.

scientific article published in January 1980

Low molecular weight EPS II of Rhizobium meliloti allows nodule invasion in Medicago sativa.

scientific article published on August 1996

Molecular determinants of a symbiotic chronic infection.

scientific article published on January 2008

Mutagenesis and other responses induced by DNA damage in Escherichia coli

scientific article published on 01 August 1982

Mutagenesis and repair deficiencies of Escherichia coli umuC mutants are suppressed by the plasmid pKM101 ⬇️

scientific article published on April 17, 1979

NMR Structure and Dynamics of the C-Terminal Domain from Human Rev1 and Its Complex with Rev1 Interacting Region of DNA Polymerase η

scientific article

NMR studies of succinoglycan repeating-unit octasaccharides from Rhizobium meliloti and Agrobacterium radiobacter

scientific article published on 01 December 1995

New discoveries linking transcription to DNA repair and damage tolerance pathways ⬇️

scientific article published on January 1, 2011

Novel role for the C terminus of Saccharomyces cerevisiae Rev1 in mediating protein-protein interactions.

scientific article published on 21 August 2006

Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics

scientific article

P-azidoiodoacetanilide, a new short photocrosslinker that has greater cysteine specificity than p-azidophenacyl bromide and p-azidobromoacetanilide

scientific article published on 01 December 1995

PMR or the self-complementary oligoribonucleotide CpCpGpG.

scientific article

Plasmid (pKM101)-mediated enhancement of repair and mutagenesis: Dependence on chromosomal genes in Escherichia coli K-12 ⬇️

scientific article published on March 28, 1977

Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis

scientific article

Posttranslational modification of the umuD-encoded subunit of Escherichia coli DNA polymerase V regulates its interactions with the beta processivity clamp

scientific article

Proteasomal regulation of the mutagenic translesion DNA polymerase, Saccharomyces cerevisiae Rev1 ⬇️

scientific article published on January 11, 2011

Proteins required for ultraviolet light and chemical mutagenesis. Identification of the products of the umuC locus of Escherichia coli

scientific article published on 01 February 1983

Proteomic alterations explain phenotypic changes in Sinorhizobium meliloti lacking the RNA chaperone Hfq.

scientific article

Pseudo-B12 joins the cofactor family.

scientific article

REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks

scientific article published on 09 November 2020

Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products.

scholarly article

Regulation of damage-inducible genes in Escherichia coli

scientific article published on 01 September 1982

Restriction endonuclease cleavage map of pKM101: relationship to parental plasmid R46.

scientific article

Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cancer

scientific article published on 03 November 2020

Rhizobium meliloti mutants that fail to succinylate their calcofluor-binding exopolysaccharide are defective in nodule invasion

scientific article published on 01 November 1987

Role of BacA in lipopolysaccharide synthesis, peptide transport, and nodulation by Rhizobium sp. strain NGR234.

scientific article

Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli

scientific article

SOS-regulated proteins in translesion DNA synthesis and mutagenesis

scientific article (publication date: October 1995)

Seeking a niche: putative contributions of the hfq and bacA gene products to the successful adaptation of the brucellae to their intracellular home.

scientific article

Similar requirements of a plant symbiont and a mammalian pathogen for prolonged intracellular survival.

scientific article

Sinorhizobium meliloti bluB is necessary for production of 5,6-dimethylbenzimidazole, the lower ligand of B12

scholarly article

Sinorhizobium meliloti requires a cobalamin-dependent ribonucleotide reductase for symbiosis with its plant host.

scientific article

Skiing the black diamond slope: Progress on the biochemistry of translesion DNA synthesis ⬇️

scientific article published on September 1, 1998

Steric gate variants of UmuC confer UV hypersensitivity on Escherichia coli.

scientific article published on 29 May 2009

Striking complexity of lipopolysaccharide defects in a collection of Sinorhizobium meliloti mutants

scientific article

Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) ζ, and Pol κ ⬇️

scientific article published on August 2, 2012

Structural studies of a novel exopolysaccharide produced by a mutant of Rhizobium meliloti strain Rm1021

scientific article published on 01 May 1990

Structure of the endonuclease domain of MutL: unlicensed to cut.

scientific article

Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapy

scientific article

Symbiotic mutants of Rhizobium meliloti that uncouple plant from bacterial differentiation

scientific article published on 01 April 1985

The Ada protein acts as both a positive and a negative modulator of Escherichia coli's response to methylating agents.

scientific article published on October 1994

The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant ⬇️

scientific article published on October 26, 2010

The Rhizobium meliloti ExoK and ExsH glycanases specifically depolymerize nascent succinoglycan chains ⬇️

scientific article published on April 28, 1998

The Sinorhizobium meliloti RNA chaperone Hfq mediates symbiosis of S. meliloti and alfalfa

scientific article

The Sinorhizobium meliloti sensor histidine kinase CbrA contributes to free-living cell cycle regulation ⬇️

scientific article published on May 31, 2013

The Y-family of DNA polymerases

scientific article (publication date: July 2001)

The critical mutagenic translesion DNA polymerase Rev1 is highly expressed during G(2)/M phase rather than S phase

scholarly article

The effects of the ultraviolet-protecting plasmids pKM101 and R205 on DNA polymerase I activity in Escherichia coli K-12 ⬇️

scientific article published on April 1, 1979

The groE gene products of Escherchia coli are dispensable for mucA+B+-dependent UV mutagenesis ⬇️

scientific article published on September 1, 1994

The highly conserved bacterial RNase YbeY is essential in Vibrio cholerae, playing a critical role in virulence, stress regulation, and RNA processing

scientific article

The type IV secretion system of Sinorhizobium meliloti strain 1021 is required for conjugation but not for intracellular symbiosis.

scientific article

The unusual UBZ domain of Saccharomyces cerevisiae polymerase η

scientific article

To cleave or not to cleave? Insights from the LexA crystal structure.

scientific article

Transcriptional modulator NusA interacts with translesion DNA polymerases in Escherichia coli.

scientific article published on 7 November 2008

Two processivity clamp interactions differentially alter the dual activities of UmuC.

scientific article

UmuD(2) inhibits a non-covalent step during DinB-mediated template slippage on homopolymeric nucleotide runs.

scientific article

Unconventional Ubiquitin Recognition by the Ubiquitin-Binding Motif within the Y Family DNA Polymerases ι and Rev1

scientific article

Unraveling the physiological complexities of antibiotic lethality.

scientific article published on 10 September 2014

Visualization of Mismatch Repair in Bacterial Cells ⬇️

scientific article published on December 1, 2001

umuDC-dnaQ Interaction and its implications for cell cycle regulation and SOS mutagenesis in Escherichia coli.

scientific article

umuDC-mediated cold sensitivity is a manifestation of functions of the UmuD(2)C complex involved in a DNA damage checkpoint control

scientific article

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