List of works - Tobias Schmid

A New Immunomodulatory Role for Peroxisomes in Macrophages Activated by the TLR4 Ligand Lipopolysaccharide

scientific article

A combination of hypoxia and lipopolysaccharide activates tristetraprolin to destabilize proinflammatory mRNAs such as tumor necrosis factor-alpha

scientific article published on 16 July 2010

AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia

publication published on 08 June 2021

Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600 ⬇️

scientific article

Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L.

scientific article

Betulinic acid suppresses NGAL-induced epithelial-to-mesenchymal transition in melanoma ⬇️

scientific article published on June 1, 2013

Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4. ⬇️

scientific article

Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia

scientific article published on 20 February 2018

Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages ⬇️

scientific article published on December 14, 2012

Development of a high-throughput cell-based reporter assay to identify stabilizers of tumor suppressor Pdcd4.

scientific article

Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4

scientific article

Downregulation of programmed cell death 4 by inflammatory conditions contributes to the generation of the tumor promoting microenvironment

scientific article

Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1 ⬇️

scientific article published on October 2, 2012

Erratum: Tristetraprolin regulation of interleukin-22 production.

scientific article published on 18 December 2015

Functional RNA Dynamics Are Progressively Governed by RNA Destabilization during the Adaptation to Chronic Hypoxia

scientific article published on 22 May 2022

Glucocorticoid-induced leucine zipper is downregulated in human alveolar macrophages upon Toll-like receptor activation.

scientific article

HIF-1 and p53: communication of transcription factors under hypoxia.

scientific article

HIF-1alpha and p53 as targets of NO in affecting cell proliferation, death and adaptation.

scientific article

HIF-1α protein is upregulated in HIF-2α depleted cells via enhanced translation

scientific article published on 02 May 2012

Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1α and Epithelial-Mesenchymal Transition

scientific article published on 6 February 2017

IL-4 reduces the proangiogenic capacity of macrophages by down-regulating HIF-1α translation

scientific article published on 4 September 2013

Inactivation of tristetraprolin in chronic hypoxia provokes the expression of cathepsin B.

scientific article

Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages.

scientific article

Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation

scientific article

Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function

scientific article published in 2022

Lights on for low oxygen: a noninvasive mouse model useful for sensing oxygen deficiency

scientific article published on 01 February 2006

Lymphotoxin α, a novel target of posttranscriptional gene regulation by HuR in HepG2 cells

scientific article

Macrophage HIF-2α regulates tumor-suppressive Spint1 in the tumor microenvironment

scientific article published on 22 August 2019

Macrophages attenuate the transcription of CYP1A1 in breast tumor cells and enhance their proliferation

scientific article published in PLoS ONE

MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization.

scientific article published on 17 February 2010

NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.

scientific article published on October 2005

PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

scientific article published on 15 January 2004

Redox control of inflammation in macrophages

scientific article published on 06 March 2013

Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids.

scientific article published in June 2010

Suppression of hypoxia-inducible factor-1α contributes to the antiangiogenic activity of red propolis polyphenols in human endothelial cells.

scientific article published on 25 January 2012

The RNA-binding protein HuR inhibits expression of CCL5 and limits recruitment of macrophages into tumors

scientific article published on 21 July 2017

Translation of TNFAIP2 is tightly controlled by upstream open reading frames

scientific article published on 07 August 2019

Tricyclic guanidine alkaloids from the marine sponge Acanthella cavernosa that stabilize the tumor suppressor PDCD4.

scientific article

Tristetraprolin regulation of interleukin-22 production

scientific article

Tumor hypoxia and cancer progression.

scientific article

Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaB-dependent pathway

scientific article

Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis.

scientific article published on April 2016

p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).

scientific article published on May 2004

uORF-Tools-Workflow for the determination of translation-regulatory upstream open reading frames

scientific article published on 12 September 2019

List of works by Tobias Schmid

A New Immunomodulatory Role for Peroxisomes in Macrophages Activated by the TLR4 Ligand Lipopolysaccharide

A combination of hypoxia and lipopolysaccharide activates tristetraprolin to destabilize proinflammatory mRNAs such as tumor necrosis factor-alpha

AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia

Actinopolysporins A-C and tubercidin as a Pdcd4 stabilizer from the halophilic actinomycete Actinopolyspora erythraea YIM 90600 ⬇️

Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L.

Betulinic acid suppresses NGAL-induced epithelial-to-mesenchymal transition in melanoma ⬇️

Cryptocaryols A-H, α-pyrone-containing 1,3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4. ⬇️

Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia

Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages ⬇️

Development of a high-throughput cell-based reporter assay to identify stabilizers of tumor suppressor Pdcd4.

Diaryl Disulfides as Novel Stabilizers of Tumor Suppressor Pdcd4

Downregulation of programmed cell death 4 by inflammatory conditions contributes to the generation of the tumor promoting microenvironment

Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1 ⬇️

Erratum: Tristetraprolin regulation of interleukin-22 production.

Functional RNA Dynamics Are Progressively Governed by RNA Destabilization during the Adaptation to Chronic Hypoxia

Glucocorticoid-induced leucine zipper is downregulated in human alveolar macrophages upon Toll-like receptor activation.

HIF-1 and p53: communication of transcription factors under hypoxia.

HIF-1alpha and p53 as targets of NO in affecting cell proliferation, death and adaptation.

HIF-1α protein is upregulated in HIF-2α depleted cells via enhanced translation

Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1α and Epithelial-Mesenchymal Transition

IL-4 reduces the proangiogenic capacity of macrophages by down-regulating HIF-1α translation

Inactivation of tristetraprolin in chronic hypoxia provokes the expression of cathepsin B.

Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages.

Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation

Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function

Lights on for low oxygen: a noninvasive mouse model useful for sensing oxygen deficiency

Lymphotoxin α, a novel target of posttranscriptional gene regulation by HuR in HepG2 cells

Macrophage HIF-2α regulates tumor-suppressive Spint1 in the tumor microenvironment

Macrophages attenuate the transcription of CYP1A1 in breast tumor cells and enhance their proliferation

MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization.

NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.

PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.

Redox control of inflammation in macrophages

Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids.

Suppression of hypoxia-inducible factor-1α contributes to the antiangiogenic activity of red propolis polyphenols in human endothelial cells.

The RNA-binding protein HuR inhibits expression of CCL5 and limits recruitment of macrophages into tumors

Translation of TNFAIP2 is tightly controlled by upstream open reading frames

Tricyclic guanidine alkaloids from the marine sponge Acanthella cavernosa that stabilize the tumor suppressor PDCD4.

Tristetraprolin regulation of interleukin-22 production

Tumor hypoxia and cancer progression.

Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaB-dependent pathway

Tumour stroma-derived lipocalin-2 promotes breast cancer metastasis.

p300 relieves p53-evoked transcriptional repression of hypoxia-inducible factor-1 (HIF-1).

uORF-Tools-Workflow for the determination of translation-regulatory upstream open reading frames