Search filters

List of works by Antonio del Sol

A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion

scientific article published on 25 May 2021

A Generalized Gene-Regulatory Network Model of Stem Cell Differentiation for Predicting Lineage Specifiers

scientific article published on 12 August 2016

A complex of the ubiquitin ligase TRIM32 and the deubiquitinase USP7 balances the level of c-Myc ubiquitination and thereby determines neural stem cell fate specification

scientific article published on 13 June 2018

A computational strategy for predicting lineage specifiers in stem cell subpopulations.

scientific article published on 2 September 2015

A differential network analysis approach for lineage specifier prediction in stem cell subpopulations

scientific article

A framework for computational and experimental methods: Identifying dimerization residues in CCR chemokine receptors

scientific article published on 01 September 2005

A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities

A general strategy for cellular reprogramming: The importance of transcription factor cross-repression ⬇️

scientific article published on October 1, 2013

A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition

scientific article

A systems biology approach to identify niche determinants of cellular phenotypes.

scientific article published on 15 September 2016

Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease

scientific article published on 19 June 2017

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood

scientific article published on 27 November 2019

An integrative method to predict signalling perturbations for cellular transitions

scientific article published on 01 July 2019

Author Correction: Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

scientific article published in 2023

Automatic methods for predicting functionally important residues

scientific article published on 01 February 2003

Big-Data-Driven Stem Cell Science and Tissue Engineering: Vision and Unique Opportunities.

scientific article

Bioinformatics Tools for Genome-Wide Epigenetic Research

scientific article published on January 2017

Computational Stem Cell Biology: Open Questions and Guiding Principles

scientific article published on 01 January 2021

Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy

scientific article published on 16 February 2019

Concise review: a population shift view of cellular reprogramming

scientific article published on June 2014

Detecting cellular reprogramming determinants by differential stability analysis of gene regulatory networks

scientific article

Discrete Logic Modelling Optimization to Contextualize Prior Knowledge Networks Using PRUNET.

scientific article published on 9 June 2015

Energetic determinants of protein binding specificity: insights into protein interaction networks

scientific article published in April 2009

Evolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human

scientific article

FIGG: simulating populations of whole genome sequences for heterogeneous data analyses

scientific article

FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age

scientific article published on 26 October 2020

FunRes: resolving tissue-specific functional cell states based on a cell-cell communication network model

scientific article published on 12 November 2020

Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages

scientific article published on 12 February 2016

Gene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain.

scientific article

Gene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease.

scientific article

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

scientific article

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes

scientific article published on 27 August 2013

Hippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.

scientific article published on 20 July 2014

HuR/ELAVL1 drives malignant peripheral nerve sheath tumour growth and metastasis

scientific article published on 21 April 2020

Identification of amino acid residues crucial for chemokine receptor dimerization.

scientific article published on 11 January 2004

Identification of large-scale genomic variation in cancer genomes using in silico reference models

scientific article

Identifying niche-mediated regulatory factors of stem cell phenotypic state: a systems biology approach.

scientific article published on 17 January 2017

Integrating pathways of Parkinson's disease in a molecular interaction map.

scientific article published on 07 July 2013

Integrative Computational Network Analysis Reveals Site-Specific Mediators of Inflammation in Alzheimer's Disease

scientific article published on 2 March 2018

Integrative and perturbation-based analysis of the transcriptional dynamics of TGFβ/BMP system components in transition from embryonic stem cells to neural progenitors

scientific article published on 13 December 2019

Ligand binding and circular permutation modify residue interaction network in DHFR.

scientific article

Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients.

scientific article

Methyl side-chain dynamics prediction based on protein structure.

scientific article

Modeling Cellular Differentiation and Reprogramming with Gene Regulatory Networks

scientific article published on 01 January 2019

Modeling heterogeneity in the pluripotent state: A promising strategy for improving the efficiency and fidelity of stem cell differentiation

scientific article published on 19 June 2016

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

scientific article

Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages

scientific article published in January 2007

Multiomics data integration unveils core transcriptional regulatory networks governing cell-type identity

scientific article published on 24 August 2020

Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages

scientific article published on 08 June 2022

PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells

scientific article published on January 2012

PPARγ population shift produces disease-related changes in molecular networks associated with metabolic syndrome.

scientific article

Predicting missing expression values in gene regulatory networks using a discrete logic modeling optimization guided by network stable states.

scientific article published on 31 August 2012

Prediction of Chromatin Accessibility in Gene-Regulatory Regions from Transcriptomics Data

scientific article

Prediction of disease-gene-drug relationships following a differential network analysis

scientific article published on 14 January 2016

Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms ⬇️

scientific article

Prox1 Is Required for Oligodendrocyte Cell Identity in Adult Neural Stem Cells of the Subventricular Zone

scientific article published on 12 April 2016

Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain

scientific article published on 28 February 2019

RefBool: a reference-based algorithm for discretizing gene expression data.

scientific article

Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere's Disease

scientific article published on 13 December 2017

SeesawPred: A Web Application for Predicting Cell-fate Determinants in Cell Differentiation

scientific article published in Scientific Reports

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

scientific article published in 2022

SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies

scientific article published on 07 November 2019

Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells.

scientific article

Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects

scientific article published on 24 July 2019

Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons

scientific article published on 13 October 2017

Small-world network approach to identify key residues in protein-protein interaction

scientific article published on 01 February 2005

Sorting signal targeting mRNA into hepatic extracellular vesicles

scientific article

Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival.

scientific article published on 28 May 2015

Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis

scientific article published on 30 December 2019

The Importance of Computational Modeling in Stem Cell Research

scientific article published on 13 August 2020

The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity

scientific article published in January 2018

The RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs

scientific article

The modular organization of domain structures: insights into protein-protein binding

scientific article

The origin of allosteric functional modulation: multiple pre-existing pathways

scientific article published on August 2009

Topology of small-world networks of protein-protein complex structures

scientific article published on 19 January 2005

TransSynW: A single-cell RNA-sequencing based web application to guide cell conversion experiments

scientific article published on 08 October 2020

Transcriptional synergy as an emergent property defining cell subpopulation identity enables population shift.

scientific article published on 3 July 2018

Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells

scientific article published on 24 July 2015

TreeDet: a web server to explore sequence space

scientific article

Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus

scientific article

Paulina is supported by:

About Paulina

Help